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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-anal- ysis 显示文摘 | Chu S G Becker R C Berger P B | 2010 | J Thromb Haemost2010，8，1： | 1 |
| 3 | Identifying optimal spec- tral bands from in situ measurements of Great Lakes coastal wetlands using second-derivative analysis显示文摘 | BECKER B L LUSCH D P QI J U | 2005 | Remote Sensing of Environment2005，97，： | 1 |
| 4 | Separate effects of ischemia and reperfusion on vascular permeability in ventilated ferret lungs显示文摘 | Becker P M Pearse D B Permutt S etal | 1992 | J Appl Physiol1992，73，6： | 1 |
| 5 | Significant leukocyte and platelet retention during pulmonary passage after declamping of the aorta in CABG patients显示文摘 | Massaudy P Zahler S Becker B F | 1999 | Eur J Med Res1999，4，： | 1 |
| 6 | A General Rule for Disk and Hemisphere Partition into Equal-area Cells显示文摘 | BECKERS B BECKERS P | 2012 | Computational Geometry2012，45，7： | 1 |
| 7 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 8 | Online Peer-to-Peer Lending-a Literature显示文摘 | Bachmann A Becker A Buerckner D Hilker M Kock F Lehmann M Tiburtius P Funk B | | 0，，02： | 1 |
| 9 | Fatigue life prediction for cord-rubber composite tires using a global-local finite element method显示文摘 | Han Y H Becker E B Farhenthold E P | 2004 | Tire Science and Technology2004，32，1： | 1 |
| 10 | Moleular background of VS and weak C expression in blacks显示文摘 | Faas B W Beckers E M Wildoer P | 1997 | Transfusion1997，37，1： | 1 |
| 11 | HR as a Source Ofshareholder Value : Research and Recommendations 显示文摘 | Becker B Huseiid M Pickus P Spratt M | 1997 | Human Resource Management1997，36，1： | 1 |
| 12 | Identifying optimal spectral bands from in situ measurements of Great Lakes coastal wetlands using second-derivative analysis显示文摘 | BECKER B L DAVID P L QI J G | 2005 | Remote Sensing of Environment2005，97，2： | 1 |
| 13 | Renal disease and hypertension in non-insulin-dependent diabetes mellitus显示文摘 | Ismail N Becker B Strzelczyk P | 1999 | Kidney Int1999，55，1： | 1 |
| 14 | Increased extracellular dopamine in the nucleus accumbens and striatum of the female rat during paced copulatory behavior 显示文摘 | Mermelstein P G Becker J B | 1995 | Behav Neurosci1995，109，2： | 1 |
| 15 | Histone acetyhtion: A switch between repressive and permissive chromatin 显示文摘 | Eberharter A Becker P B | 2002 | EMBO Rep2002，3，： | 1 |
| 16 | Candida albicans septin mutants are defective for invasive growth and virulence显示文摘 | Warenda A J Kauffman S Sherrill T P Becker J M Konopka J B | 2003 | Infect Immun2003，71，： | 1 |
| 17 | Stochastic Optim ization of Multiple Reservoir System Operation显示文摘 | Braga B P F Yeh WW-G Becker L Barros M T E | 1991 | Journal of Water Resources Planning and Management1991，117，4： | 1 |
| 18 | Utstein-style guidelines for uniform reporting of laboratory CPR research显示文摘 | IDRIS A H BECKER L B ORNATO J P | 1996 | Circulation1996，94，9： | 1 |
| 19 | Histone acetylation: a switch between repressive and permissive chromatin 显示文摘 | Eberharter A Becker P B | 2002 | EMBO Rep2002，3，： | 1 |
| 20 | Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis 显示文摘 | Ammori B J Becker KL Kite P | 2003 | Pancreas2003，27，： | 1 |
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