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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Different types of scaffolds for reconstruction of the urinary tract by tissue engineering显示文摘 | Brehmer B Rohrmann D Becker C | 2007 | Urol Int2007，78，1： | 1 |
| 3 | CT of coronary artery disease显示文摘 | SCHOEPF U J BECKER C R OHNESORGE B M | 2004 | Radiology2004，23，1： | 1 |
| 4 | Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-anal- ysis 显示文摘 | Chu S G Becker R C Berger P B | 2010 | J Thromb Haemost2010，8，1： | 1 |
| 5 | Volumetric analysis of simulated alveolar cleft defects and bone grafts using cone beam computed tomography 显示文摘 | Amirlak B Tang C J Becker D | 2013 | Plast Reeonstr Surg2013，131，4： | 1 |
| 6 | Cardiac imaging with rapid retrospective ECG synchronized multilevel spiral CT显示文摘 | Ohnesorge B Flohr T Becker C | 2000 | Radiology2000，40，4： | 1 |
| 7 | Cardiac imaging by means of electrocardiographically gated multisection spiral CT: initial experience显示文摘 | Ohnesorge B Flohr T Becker C | 2000 | Radiology2000，217，2： | 1 |
| 8 | Cardiac imaging by means electrocardiographically gated multisection spiral CT: initial experience显示文摘 | Ohnesorge B Flohr T Becker C | 2000 | Radiology2000，217，2： | 1 |
| 9 | Human follicle- stimulating hormone beta -subunit gene encodes multiple messenger ribonucleic acids显示文摘 | Jameson J L Becker C B Lindell C M | 1958 | Mol Endocrinol1958，2，9： | 1 |
| 10 | Real-time quantitative polymerase chain reaction to assess gene transfer显示文摘 | Becker K Pan D Whitley C B | 1999 | Hum Gene Ther1999，10，： | 1 |
| 11 | Different types of scaffolds for reconstruction of the urinary tract by tissue engineering 显示文摘 | Brehmer B Rohrmann D Becker C | 2007 | Urol Int2007，78，1： | 1 |
| 12 | Reasons for the lack of argumentation and debate in the Far East显示文摘 | | 1986 | International Journal of Intercultural Relations1986，10，1： | 1 |
| 13 | Factors relating to the use of physical restraints in psychogeriatric care:A paradigm for elder abuse显示文摘 | Bredthauer D Becker C Eichner B | 2005 | Z Gerontol Geriatr2005，38，1： | 1 |
| 14 | Material trend mechanism and Stahlund Breton material 显示文摘 | DENKENA B TONSHOFF H K BECKER J C | 2003 | Industrial Diamond Review2003，11，： | 1 |
| 15 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 16 | Cardiac imaging by means of electroeardiographically gated muhisection spiral CT: initial experience 显示文摘 | Ohnesorge B Flohr T Becker C | 2000 | Radiology2000，217，4： | 1 |
| 17 | Different types of scaf- folds for reconstruction of the urinary tract by tissue engineering 显示文摘 | Brehmer B Rohrmann D Becker C | 2007 | Urol Int2007，78，1： | 1 |
| 18 | Multislice helical CT of the heart with retrospective ECG gating: reduction of radiation exposure by ECG-controlled tube current modulation显示文摘 | Jakobs T F Becker C R Ohnesorge B M | 2002 | Eur Radial2002，12，： | 1 |
| 19 | Real-time quantitative polymerase chain reaction to assess gene transfer 显示文摘 | Becker K Pan D Whitley C B | 1999 | Hum GeneTher1999，10，15： | 1 |
| 20 | Factors of Contribute to Genetic Variation for Nutrient Efficiency of Crop Plants 显示文摘 | Sattelmacher B Horst W J Becker H C | 1994 | Plant Soil1994，157，： | 1 |
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