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| 1 | Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains 显示文摘 | TORREY E F BARCI B M WEBSTER M J | 2005 | Biol Psychiatry2005，57，3： | 1 |
| 2 | Prevalence of IFNL3 rs4803217 single nucleotide polymorphism and clinical course of chronic hepatitis C显示文摘AIM To evaluate the association of IFNL3(IL28B) SNP rs4803217 with severity of disease and treatment outcome in chronic hepatitis C(CHC).METHODS The study enrolled 196 CHC Polish patients(82 women and 114 men in age 20-64) infected with hepatitis C virus(HCV) genotype 1. They were treatment na?ve and qualified to pegylated interferon alpha(PEG-IFN-α) and ribavirin(RBV) therapy. The analyzed baseline parameters included: degree of inflammation, stage of fibrosis, viral load as well as alanine aminotransferase(ALT), asparagine aminotransferase(AST) and total bilirubin(TBIL). The analysis of response to therapy included: sustained virological response(SVR), defined as undetectable serum HCV RNA level six month after completion of 48-wk therapy, and relapse, defined as achieving undetectable viral load at the end of treatment but not SVR. HCV genotyping and HCV RNA quantification were performed using commercially available tests. DNA was isolated from peripheral blood mononuclear cells or from buccal cell swabs. In addition to rs4803217, also single nucleotide polymorphisms(SNPs)(rs12979860, rs8099917 and rs12980275) of known significance in predicting of HCV clearance were analyzed. SNPs were determined by high resolution melt analysis and confirmed by sequencing of amplicons. RESULTS Frequency of rs4803217 genotypes in studied group was as follows: 27.55%; 54.59% and 17.86% for CC, CA and AA, respectively. The rs4803217 SNP, similar to other analyzed SNPs, was not associated with severity of CHC(grade of inflammation, stage of fibrosis, baseline viral load as well as biochemical parameters: ALT, AST, TBIL). It was demonstrated that the rs4803217 C allele is associated with SVR(C vs A: P < 0.0001; dose of C allele: P = 0.0002) and nonrelapse(C vs A: P = 0.001; dose of C allele: P = 0.002). Moreover, it was found that patients with CC genotype have significantly higher response rates as compared with CA/AA patients(P < 0.0001), whereas patients carrying A allele are significantly predisposed to relapse after treatment(P = 0.0007). Moreover, the association of rs4803217 with SVR was comparable to that of rs12979860 and stronger as observed for rs12980275 and rs8099917. Association of rs4803217 with relapse, was the strongest as compared with the other SNPs. The analysis of combined rs4803217 and rs8099917 genotypes demonstrated that additional genotyping of rs8099917 had no significant impact on the prediction of SVR. Multivariate analysis revealed that among analyzed SNPs only rs4803217 is an independent predictor of SVR(P = 0.016) and relapse(P = 0.024). CONCLUSION The rs4803217 SNP is a strong, independent and superior predictor of SVR and relapse in HCV genotype 1 infected CHC patients treated with PEG-IFN-α and RBV. | Bogna Swiatek-Koscielna Ewelina Kaluzna Ewa Strauss Jerzy Nowak Iwona Bereszyńska Ewelina Gowin Jacek Wysocki Jolanta Rembowska Dominika Barcińska Iwona Mozer-Lisewska Danuta Januszkiewicz-Lewandowska | 2017 | World Journal of Gastroenterology2017，23，21： | 1 |
| 3 | Longitudinal analysis of herpes simplex virus - specific CD4+ cell clonotypes in infected tissues and blood 显示文摘 | Barcy S Huang ML Corey L | 2005 | J Infect Dis2005，191，12： | 1 |
| 4 | Makers of viral in monozygotic twins discordant for chronic fatigue syndrome显示文摘 | Koelle DM Barcy S Huang ML et al | 2002 | CID2002，35，1： | 1 |
| 5 | Reinvestigation of the alpha-decays of ^249 Cf and ^233 U 显示文摘 | AKA A K ARDISSON G BARCI V | 1996 | Nucl & Methods in Phys Res A1996，369，： | 1 |
| 6 | Molecular abnormalities of the hippocampus in severe psychiatric illness : postmortem findings from the Stanley Neuropa- thology Consortium显示文摘 | Knable MB Barci BM Webster M J | 2004 | Mol Psychia- try2004，9，62： | 1 |
| 7 | Family therapy in a transitional society显示文摘 | Furedi J Barcy M Kapusi G | 1993 | Psychiatry1993，56，4： | 1 |
| 8 | Complete modeling of rotary ultrasonic motors actuated by raveling flexural waves显示文摘 | BAOX BARCY | 2000 | Proceedings of SPIE2000，3992，： | 1 |
| 9 | Long Term Persistence of Herpes Simplex Virus-Specific CD8+ CTL in Persons with Frequently Recurring Genital Herpes显示文摘 | Posavad C M Huang M L Barcy S | 2000 | J Immunol2000，165，2： | 1 |
| 10 | Wavelet based fractal analysis of DNA sequences 显示文摘 | Ameodo A d' Aubenton-Carafa Y Barcy E | 1996 | Physica D1996，，96： | 1 |
| 11 | 显示文摘 | Posavad CM Huang ML Barcy S | 2000 | J Immunol2000，165，2： | 1 |
| 12 | Long term persistence of herpes simplex virus-specific CD8^+ CTL in persons with frequently recurring genital herpes显示文摘 | Posavad C M Huang M L Barcy S | 2000 | J Immunol2000，165，2： | 1 |
| 13 | A New Method of Rotor Resistance Estimation for Vector Controlled In- duction Machines 显示文摘 | Wade Scott Dunnigan Matthew W Willions Barcy W | 1997 | IEEE Transactions on Industral Electronics1997，44，2： | 1 |
| 14 | Neurochemical markers for schizophrenia,bipolar disorder,and major depression in postmortem brains显示文摘 | Torrey EF Barci BM Webster MJ | | 0，，03： | 1 |
| 15 | 波兰生活用纸零售市场的发展显示文摘2018年,波兰居家用生活用纸的人均消费量接近7kg,在东欧仅次于克罗地亚和斯洛文尼亚,是俄罗斯的两倍多。预计到2023年,波兰居家用生活用纸人均消费量将接近法国和英国等西欧主要发达市场的水平。由于消费基数较高,预计在2018-2023年期间,波兰生活用纸零售量的年均复合增长率将放缓至5%,2023年生活用纸的零售量将达到34万t。尽管随着市场的发展,增长速度放缓不可避免,但波兰生活用纸零售市场估计仍有13万t的需求潜力。 | Eka Barcys | 2020 | 生活用纸2020，20，3： | 0 |
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