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| 1 | Should multi-gene panel testing replace limited BRCA1/2 testing? A review of genetic testing for hereditary breast and ovarian cancers显示文摘Clinical testing of patients for hereditary breast and ovarian cancer syndromes began in the mid-1990s with the identification of the BRCA1 and BRCA2 genes.Since then,mutations in dozens of other genes have been correlated to increased breast,ovarian,and other cancer risk.The following decades of data collection and patient advocacy allowed for improvements in medical,legal,social,and ethical advances in genetic testing.Technological advances have made it possible to sequence multiple genes at once in a panel to give patients a more thorough evaluation of their personal cancer risk.Panel testing increases the detection of mutations that lead to increased risk of breast,ovarian,and other cancers and can better guide individualized screening measures compared to limited BRCA testing alone.At the same time,multi-gene panel testing is more time-and cost-efficient.While the clinical application of panel testing is in its infancy,many problems arise such as lack of guidelines for management of newly identified gene mutations,high rates of variants of uncertain significance,and limited ability to screen for some cancers.Through on-going concerted efforts of pooled data collection and analysis,it is likely that the benefits of multi-gene panel testing will outweigh the risks in the near future. | Nimmi S Kapoor Kimberly C Banks | 2016 | World Journal of Surgical Procedures2016，6，1： | 2 |
| 2 | Laboratory studies with nine amidinohydrazones,a promising new class of bait eoxieants for control of red imported fire ants显示文摘 | Williams D F Lofgren C S Banks W A | 1980 | Journal of Economic Entomology1980，73，： | 1 |
| 3 | Analysis of RC beams strong thinned with mechanically fastened FRP (MF-FRP) strips 显示文摘 | Bank L C Aurora D | 2007 | Composite Structure2007，79，2： | 1 |
| 4 | An askl-p38 signalling pathway mediates hydrogen peroxide-induced toxicity in ng108-15 neuronal cells显示文摘 | Nomura K Lee M Banks C Lee G Morris BJ | | 0，，： | 1 |
| 5 | A model specification for FRP composites for civil engineering structures显示文摘 | Lawrence C Bank T.Russell Gentry Benjamin P Thompson Jeffrey S Russell | 2003 | Construction and Building Materials2003，，6： | 1 |
| 6 | Influence of inoculum to substrate ratio on the biochemical methane potential of maize in batch tests显示文摘 | Raposo F Banks C J Siegert I | 2006 | Process Biochemistry2006，41，： | 1 |
| 7 | Effect of Dietary Calcium and Vitamin D3 on Calcium and Phosphorus Retention in White Pekin Ducklings 显示文摘 | Rush J K Angel C R Banks K M | 2005 | Poult Sci2005，84，： | 1 |
| 8 | Electroanalytical determination of cadmium(II)and lead(II)using an in-situbismuth film modified edge plane pyrolytic graphite electrode显示文摘 | KACHOOSANGI R T BANKS C E JI X | 2007 | Analytical Sciences2007，23，3： | 1 |
| 9 | Effects of extraction conditions and alkali type on yield and composition of wheat straw hemicellulose显示文摘 | LAWTHER J M SUN R C BANKS W B | 1996 | J Appl Polym Sci1996，60，11： | 1 |
| 10 | The synthesis of1,2-cyclohexanedione dioxime(nioxime)显示文摘 | Rauh E G Smith G F Banks C V | 1945 | Journal of Organic Chemistry1945，10，： | 1 |
| 11 | The usability of digestate in organic farming显示文摘 | Clements L J Salter A M Banks C J | 2012 | Water Sci Technol2012，66，9： | 1 |
| 12 | An overview of graphene in energy production and storage appli- cations显示文摘 | BROWNSON D A C KAMPOURIS D K BANKS C E | 2011 | J Power Source2011，196，： | 1 |
| 13 | Community-based rangeland management in western China: Rationale, pilot proj- ect experiences, and policy implications 显示文摘 | BANKS T RICHARD C LI P | 2003 | Mountain Research and Development2003，23，2： | 1 |
| 14 | Comparison of several sulfluramid bait formulations for control of the red imported fire ant (Hymenoptera:Fotmicidae)显示文摘 | Banks W A Las A S Adams C T | 1992 | Journal of Entomological Science1992，27，： | 1 |
| 15 | The interaction between Cu, Pb, Zn and Ni in their biosorption onto polyurethane-immobilised Sphagnum moss 显示文摘 | ZHANG Y BANKS C | 2005 | Journal of Chemical Technology and Biotechnology2005，80，11： | 1 |
| 16 | Shear properties of pultruded glass FRP materials 显示文摘 | Bank L C | 2014 | American Society of Civil Engineers2014，2，2： | 1 |
| 17 | The dangers of proton pump inhibitor therapy 显示文摘 | Owen C Marks DJ Banks M | 2014 | Br J Hosp Med (Lond)2014，75，7： | 1 |
| 18 | Metal nanoparti-cles and related materials supported on carbon nano-tubes :methods and applications 显示文摘 | Wildgoose G Banks C Compton R | 2006 | Small2006，2，2： | 1 |
| 19 | Low temperature oxidation behavior of reactively sputtered TiN by X-ray photoelectron spectroscopy and contact resistance measurements显示文摘 | ERNSBERGER C NICKERSON J SMITH T MILLER A E BANKS D | 1986 | J Vac Sei Technol A1986，，6： | 1 |
| 20 | Comparison of efficacy of hyaluronan and hylan G-F 20 in osteoarthritis显示文摘 | Sripada P Pritchard C Bankes PF | 1999 | Arthritis Rheum1999，42，： | 1 |
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