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| 1 | Cholangiocyte anion exchange and biliary bicarbonate excretion显示文摘主要小管胆汁沿着被几个因素包括荷尔蒙, innervation/neuropeptides,和胆汁的成分影响的胆道经历使液化和硷化的一个过程。在 canaliculi 和胆汁管的酸式碳酸盐的排泄是到所谓的胆汁盐独立人士流动的产生的一个重要贡献者。酸式碳酸盐通过经由 AE2/SLC4A2-mediated Cl-/HCO3- 交换通过 Cl- 隧道,和进一步的酸式碳酸盐分泌物的激活包含氯化物流出的平行机制从 hepatocytes 和 cholangiocytes 被分泌。高血糖素和分泌素是似乎在他们的目标房间(为前者的 hepatocytes 和为后者的 cholangiocytes ) 很同样行动的二相关荷尔蒙。这些荷尔蒙与他们的特定的 G 联合蛋白质的受体交往,引起营地的细胞内部的层次和营地依赖者 Cl- 和 HCO3- 的激活的增加能分泌的机制。hepatocytes 和 cholangiocytes 看起来有在的营地应答的细胞内部的泡有房间 specific Cl- 隧道的 AE2/SLC4A2 colocalizes (在 cholangiocytes 并且还没的 CFTR 在 hepatocytes 决定了) 并且 aquaporins (在 hepatocytes 的 AQP8 和在 cholangiocytes 的 AQP1 ) 。到小管或 cholangiocyte lumenal 膜和进一步的 exocytosis 的这些泡的导致营地的协调交通国王与网导致水的增加的渗透的力量和被运动充满酸式碳酸盐的胆液排泄增多。 | Jesús M Banales Jesús Prieto Juan F Medina | 2006 | World Journal of Gastroenterology2006，12，22： | 10 |
| 2 | MicroRNAs in biliary diseases显示文摘Cholangiopathies are a group of diseases primarily or secondarily affecting bile duct cells, and result in cholangiocyte proliferation, regression, and/or transformation. Their etiopathogenesis may be associated with a broad variety of causes of different nature, which includes genetic, neoplastic, immune-associated, infectious, vascular, and drug-induced alterations, or being idiopathic. miRNAs, small non-coding endogenous RNAs that post-transcriptionally regulate gene expres sion, have been associated with pathophysiological processes in different organs and cell types, and are postulated as potential targets for diagnosis and therapy. In the current manuscript, knowledge regarding the role of miRNAs in the development and/or progression of cholangiopathies has been reviewed and the most relevant findings in this promising field of hepatology have been highlighted. | Patricia Munoz-Garrido Maite García-Fernández de Barrena Elizabeth Hijona Miguel Carracedo JoséJ G Marín Luis Bujanda Jesús M Banales | 2012 | World Journal of Gastroenterology2012，18，43： | 2 |
| 3 | Up-regulation of microRNA 506 leads to decreased C1-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis显示文摘 | Banales JM Saez E Uriz M | 2012 | Hepatology2012，56，2： | 1 |
| 4 | SR-FTIR spectroscopic preliminary findings of non-cancerous, cancerous, and hyperplastic human prostate tissues显示文摘 | PALUSZKIEWICZ C KWIATEK WM BANAL A | 2007 | Vibrat Spectrosco2007，43，1： | 1 |
| 5 | Procalcito- nin is useful in identifying bacteraemia among children with pneu- monia显示文摘 | Nascimento- Carvalho CM Cardoso MR Banal A | 2010 | Scand J Infect Dis2010，42，9： | 1 |
| 6 | Alcohol consumption on pancreatic diseases 显示文摘 | HERREROS VILLANUEVA M HIJONA E BANALES J M | 2013 | World J Gas- troenterol2013，19，5： | 1 |
| 7 | The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD) 显示文摘 | Banales JM Masyuk TV Gradilone SA | 2009 | Hepatology2009，49，1： | 1 |
| 8 | Comparison of Cyfra21-1 and SCC assays in head and neck tumours显示文摘 | Hacene K Berthelot-Ruff E | 2001 | Tumour Biol2001，22，1： | 1 |
| 9 | A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs显示文摘 | Unger EF Banal S Shou M | 1993 | Cardiovasc-Res1993，27，5： | 1 |
| 10 | Adenosine deaminase in the diagnosis of tuberculous pleural effusions显示文摘 | Banales JL Pineda PR Fitzerald JM | 1991 | Chest1991，，99： | 1 |
| 11 | Increased C-reactive protein level after coronary stent implantation in patients with stable conronary artery disease显示文摘 | Almagor M Keren A Banal S | 2003 | Am Heart J2003，145，2： | 1 |
| 12 | Matrix metalloproteinase‐10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair显示文摘 | Oihane Garcia‐Irigoyen Simone Carotti Maria U. Latasa Iker Uriarte Maite G. Fernández‐Barrena Maria Elizalde Raquel Urtasun Umberto Vespasiani‐Gentilucci Sergio Morini Jesús M. Banales William C. Parks Jose A. Rodriguez Josune Orbe Jesús Prieto Jose A. Pá | 2014 | Liver Int2014，，7： | 1 |
| 13 | Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD显示文摘 | Sergio A. Gradilone Tatyana V. Masyuk Bing Q. Huang Jesus M. Banales Guillermo L. Lehmann Brynn N. Radtke Angela Stroope Anatoliy I. Masyuk Patrick L. Splinter Nicholas F. LaRusso | 2010 | Gastroenterology2010，，1： | 1 |
| 14 | Evaluation of adenosine deaminasea ctivity in the Myobac teriumtuber culousiscul ture supernatants显示文摘 | PEREZ L BANALES J L RIVERA E | 1999 | Arch Med Res1999，30，5： | 1 |
| 15 | Shared apical sorting of anion exchanger isoforms AE2a, AE2b 1 , and AE2b 2 in primary hepatocytes显示文摘 | Victoria Aranda I?igo Mart??nez Saida Melero Jon Lecanda Jesús M. Banales Jesús Prieto Juan F. Medina | 2004 | Biochemical and Biophysical Research Communications2004，，3： | 1 |
| 16 | Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs显示文摘 | Banal S Jaklitach MT Shou M | 1994 | Circulation1994，89，5： | 1 |
| 17 | Reading and subeortical auditory function显示文摘 | Banal K Horniekel J Skoe E | 2009 | Cereb Cortex2009，19，11： | 1 |
| 18 | The sig- nificance of genetics for cholangiocarcinoma developmem显示文摘 | MARONI L PIERANTONELLI I BANALES JM | 2013 | Ann Transl Med2013，1，3： | 1 |
| 19 | Angiogenesic- induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs 显示文摘 | BANAl S JAKLISCH MT SHOU M | 1994 | Circulation1994，89，： | 1 |
| 20 | Tyrphostin AGL- 2043 during reduces neointimal formation in porcine coronary arteries 显示文摘 | Banal S Gertz SD Gavish L | 2004 | Cardiovasc Res2004，64，1： | 1 |
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