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| 1 | Pentoxifylline versus prednisolone for severe alcoholic hepatitis:A randomized controlled trial显示文摘AIM:To compare the efficacy of pentoxifylline and prednisolone in the treatment of severe alcoholic hepatitis,and to evaluate the role of different liver function scores in predicting prognosis.METHODS:Sixty-eight patients with severe alcoholic hepatitis(Maddrey score≥32)received pentoxifylline(n=34,groupⅠ)or prednisolone(n=34,groupⅡ) for 28 d in a randomized double-blind controlled study,and subsequently in an open study(with a tapering dose of prednisolone)for a total of 3 mo,and were followed up over a period of 12 mo.RESULTS:Twelve patients in groupⅡdied at the end of 3 mo in contrast to five patients in groupⅠ.The probability of dying at the end of 3 mo was higher in groupⅡas compared to groupⅠ(35.29%vs 14.71%,P=0.04;log rank test).Six patients in groupⅡ developed hepatorenal syndrome as compared to none in groupⅠ.Pentoxifylline was associated with a significantly lower model for end-stage liver disease(MELD)score at the end of 28 d of therapy(15.53±3.63 vs 17.78±4.56,P=0.04).Higher baseline Maddrey score was associated with increased mortality.CONCLUSION:Reduced mortality,improved risk-benefit profile and renoprotective effects of pentoxifylline compared with prednisolone suggest that pentoxifylline is superior to prednisolone for treatment of severe alcoholic hepatitis. | Binay Krishna De Subhabrata Gangopadhyay Deep Dutta Sumanta Das Baksi Adyapad Pani Pramit Ghosh | 2009 | World Journal of Gastroenterology2009，15，13： | 26 |
| 2 | Anti-leukemic and anti-angiogenic effects of D-Limonene on K562-implanted C57BL/6 mice and the chick chorioallantoic membrane model显示文摘Background: D-Limonene, a monoterpene from citrus fruit has been found to have chemopreventive and chemotherapeutic activities in various types of cancers. In this study, we evaluated the in vivo effect of D-Limonene on a K562-induced model of chronic myeloid leukemia(CML) in C57 BL/6 mice.Method: The tail vein injection model of K562 cells in immunocompromised C57 BL/6 mice was developed and evaluated for characteristics of the disease. The mice were treated with D-Limonene and evaluated for haematological parameters. We also evaluated the effect of D-Limonene on angiogenesis using the chick chorioallantoic membrane(CAM) assay.Results: In a complete blood count, a significant dose-dependent reduction in white blood cell, neutrophil and lymphocyte counts, but an elevation in red blood cell count and haemoglobin content was observed with D-Limonene treatment compared to the disease control or untreated group. In the CAM assay, D-Limonene produced a significant dose-dependent reduction in number of blood vessels in treatment groups compared to the vehicle-treated group.Conclusion: These studies suggest promising anti-leukemic and anti-angiogenic effects of D-Limonene in the treatment of CML. | Bhavini B.Shah Ruma Baksi Kiranj K.Chaudagar Manish Nivsarkar Anita A.Mehta | 2018 | Animal Models and Experimental Medicine2018，1，4： | 2 |
| 3 | Internal fixation of ununited femoral neck fraetures combined with muscle-pedicle bone grafting显示文摘 | Baksi D P | 1986 | J Bone Joint Surg1986，68，2： | 1 |
| 4 | Spectrophometer determination of salicylic acid in pharmaceutical formulation using as a colour developer显示文摘 | | 1989 | Analyst1989，110，： | 1 |
| 5 | Bone metabolism during antler growth in female reindeer显示文摘 | Dr. Samarendra N. Baksi Jarrett W. Newbrey | 1989 | Calcified Tissue International1989，，5： | 1 |
| 6 | Internal fixation of ununited femoral neck fractures combined with muscle-pedicle bone grafting显示文摘 | Baksi DP | | 0，，2： | 1 |
| 7 | A comparison of pharmacokinetics of felodipine in elderly and young sud]ects显示文摘 | Baksi AK Edwards JS Ahr G | 1991 | Br J Clin Pharmacol1991，31，3： | 1 |
| 8 | Long - term results ofdecompression and muscle - pedicle bone grafting forosteonecrosis of the femoral head 显示文摘 | Baksi D P Pal A K Baksi D D | 2009 | Int Orthop2009，33，1： | 1 |
| 9 | Treatment of osteonecrosis of the femoral head by drilling and muscle-pedicle bone grafting显示文摘 | Baksi DP | | 0，，2： | 1 |
| 10 | Calculating economy -wide energy intensity decline rate: The role of sectoral output and energy shares显示文摘 | SOHAM BAKSI CHRIS GREEN | 2007 | Energy Policy2007，，35： | 1 |
| 11 | 40Ar/39Ar dating of the Brunhes-Matuyama geomagnetic field reversal显示文摘 | Baksi A Hsu V Mcwilliams M O | 1992 | Science1992，256，： | 1 |
| 12 | Does a combination of two radiographs increase accuracy in detecting acid-induced periapical lesions and does it approach the accuracy of cone-beam computed tomography scanning显示文摘 | Sogur E Grondahl HG Baksi BG | 2012 | J Endod2012，38，2： | 1 |
| 13 | Prosthetic replacement of elbow for intercondylar fractures(recent or ununited)of humerus in the elderly显示文摘 | Baksi DP Pal AK Baksi D | | 0，，08： | 1 |
| 14 | Toxicity and mAChRs binding activity of Cassiopea xamachana venom from Puerto Rican coasts 显示文摘 | Radwan FF Roman LG Baksi K | 2005 | Toxicon2005，45，1： | 1 |
| 15 | Effect of propylthiouracil-induced hypothyroidism on serum levels of luteinizing hormone and follicle-stimulating hormone in the rat显示文摘 | Baksi S N | 1973 | J Endocriol1973，59，： | 1 |
| 16 | Dynamic analysis of vibrato- ry insertion process显示文摘 | KILIKEVICIUS S BAKSYS B | 2011 | Assembly Automation2011，31，3： | 1 |
| 17 | Imaging of root canal fillings : a comparison of subjective image quality between limited cone-beam CT, storage phosphor and film radiography 显示文摘 | Sogur E Baksi BG Grondahl HG | 2007 | Int Endod J2007，40，3： | 1 |
| 18 | A study of magneto-thermoelastic problems with thermal relaxation and heat sources in a three-dimensional infinite rotating elastic medium 显示文摘 | Baksi A Bera R K Debnath L | 2005 | International Journal of Engineering Science2005，43，： | 1 |
| 19 | Training programme for peer advisers in diabetes and the expert patients in diabetes显示文摘 | Baksi AK Al-Mrayat M Hogan D | 2005 | Pract Diab Int2005，22，2： | 1 |
| 20 | Internal fixation of united femoral fracture combined with muscle-pedicle bone grafting显示文摘 | Baksi D P | 1986 | J Bone Joint Surg1986，6，： | 1 |
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