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| 1 | Biofilm formation in clinical isolates of nosocomial Acinetobacter baumannii and its relationship with multidrug resistance显示文摘Objective: To check biofilm formation by Acinetobacter baumannii(A. baumannii)clinical isolates and show their susceptibility to different antibiotics and investigate a possible link between establishment of biofilm and multidrug resistance.Methods: This study was performed on clinical samples collected from patients with nosocomial infections in three hospitals of Tehran. Samples were initially screened by culture and biochemical tests for the presence of different species of Acinetobacter. Identifications were further confirmed by PCR assays. Their susceptibilities to 11 antibiotics of different classes were determined by disc diffusion method according to Clinical and Laboratory Standards Institute guidelines. The ability to produce biofilm was investigated using methods: culture on Congo red agar, microtiter plate, and test tube method.Results: From the overall clinical samples, 156 specimens were confirmed to contain A. baumannii. The bacteria were highly resistant to most antibiotics except polymyxin B.Of these isolates, 10.26% were able to produce biofilms as shown on Congo red agar.However, the percentage of bacteria with positive biofilm in test tube, standard microtiter plate, and modified microtiter plate assays were 48.72%, 66.66%, and 73.72%, respectively. At least 92% of the biofilm forming isolates were multidrug resistant.Conclusions: Since most of the multidrug resistant strains produce biofilm, it seems necessary to provide continuous monitoring and determination of antibiotic susceptibility of clinical A. baumannii. This would help to select the most appropriate antibiotic for treatment. | Ebrahim Babapour Azam Haddadi Reza Mirnejad Seyed-Abdolhamid Angaji Nour Amirmozafari | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，6： | 13 |
| 2 | The effect of peers support on postpartum depression:a single - blind randomized clinical trial显示文摘 | Kamalifard M Yavarikia P Babapour Kheiroddin J | 2013 | J Caring Sci2013，2，3： | 1 |
| 3 | GABAergic control of food intake in the meat typechickens 显示文摘 | JONAIDI H BABAPOUR V DENBOW D M | 2002 | Physiol Behav2002，76，45： | 1 |
| 4 | Neuroendoscopic placement of Ommaya reservoir into a cystic craniopharyngioma显示文摘 | Joki T Oi S Babapour B | | 0，，： | 1 |
| 5 | Chemical stimulation of the lateral hypothalamus by carbachol attenuated the formalin- induced pain behaviors in rats显示文摘 | Ezzatpanah S Babapour V Sadeghi B | 2015 | Pharmacol Biochem Behav2015，129，： | 1 |
| 6 | Dermatosis papuiosa nigra in a young child显示文摘 | Babapour R Leach J Levy H | 1993 | Pediatr Dermatol1993，10，4： | 1 |
| 7 | GABAergic control of food intake in the lneat-type chickens显示文摘 | Jonaidi H Babapour V Denbow D M | | 0，，4： | 1 |
| 8 | Fetal hydrocephalus,interauterine diagno- sis and therpy considerations: an experimental rat model 显示文摘 | Babapour B Oi S Boozari B | 2005 | Childs NervSyst2005，，21： | 1 |
| 9 | Size variation and optical absorption of sol-gel Ag nanoparticles doped SiO2 thin film 显示文摘 | Babapour A Akhavan O Moshfegh A Z | 2006 | Thin Solid Films2006，515，2： | 1 |
| 10 | GABAergie control of food intake in the meat-type chickens显示文摘 | Jonaidi H Babapour V Denbow D M | 2002 | Physiol Behav2002，76，45： | 1 |
| 11 | Glutamate ionotropic and metabotropic receptors affect feed intake in broiler cockerels显示文摘 | Baghbanzadeh A Babapour V | | 0，，： | 1 |
| 12 | 显示文摘 | Babapour A O | 2006 | Thin Solid Films2006，515，： | 1 |
| 13 | GABAergic control offood intake in the meat - type chickens 显示文摘 | JONAIDI H BABAPOUR V DENBOW D M | 2002 | Physiol Behav2002，76，45： | 1 |
| 14 | Size variation and optical absorption of sol-gel Ag nanoparti- cles doped SiO2 thin film显示文摘 | Babapour A Akhavan O Moshfegh A Z | 2006 | Thin Solid Films2006，515，： | 1 |
| 15 | Neuroen- doscopic placement of Ommaya reservoir into a cystic craniophatyn$ioma显示文摘 | Joki T Oi S Babapour B | 2002 | Childs Nerv Syst2002，18，11： | 1 |
| 16 | Fetal hydrocephalus,intrauterine diagnosis and therapy considerations:An experimental rat model显示文摘 | Babapour B Oi S Boozari B | 2005 | Childs Nerv Syst2005，21，5： | 1 |
| 17 | Fetal hydrocephalus,intrauterine diagnosis and therapy considerations:An experimental rat model显示文摘 | Babapour B Oi S Boozari B | 2005 | Childs Nerv Syst2005，21，5： | 1 |
| 18 | Neuroendoscopic placement of Ommaya reservoir into a cystic craniopharyngioma显示文摘 | Joki T Oi S Babapour B | 2002 | Childs Nerv Syst2002，18，11： | 1 |
| 19 | Intracerebroven-tricular injection of lipopolysaccharide increases gene ex-pression of connexin32 gap junction in rat hippocampus显示文摘 | Abbasian M Sayyah M Babapour Y | 2013 | Basic Clin Neurosci2013，4，4： | 1 |
| 20 | Expression of connexin 30 and connexin 32 in hippocampus of rat during epileptogenesis in a kindling model of epilepsy显示文摘理解位于 epileptogenesis 下面的分子、细胞的机制的目的产出新卓见进可以最终阻止癫痫的潜在的治疗。差距连接(GJ ) 创造在邻近的房间之间的直接细胞间的水管并且被蛋白质子单元把 connexins (Cxs ) 称为的 hexameric 形成。在 Cxs 的表示的变化影响 GJ 通讯并且能从而调制电的分泌物的传播。马头鱼尾的怪兽是涉及 epileptogenesis 的主要区域之一并且在 Cx30 在星形细胞被表示, Cx32 在神经原和 oligodendrocytes 存在的地方,有在不同房间类型之间的 GJ 的一个宽网络。在现在的学习,我们在点燃 epileptogenesis 期间在老鼠马头鱼尾的怪兽评估了 Cx30 和 Cx32 表示的变化。方法老鼠 stereotaxically 与在 basolateral 杏仁之类刺激并且记录电极被植入,它每天电子上在 afterdischarge 阀值被刺激一次。在 mRNA 和蛋白质层次, Cx30 和 Cx32 的表示在开始在马头鱼尾的怪兽被测量,在中间(在焦点的发作的获得以后),并且在结束(在概括发作的建立以后)点燃的进程,由即时 PCR 和西方的污点。结果 Cx30 mRNA 表示是在点燃并且在焦点的发作的获得以后的开始的 upregulated。当动物获得了概括发作时,当时,它是 downregulated。在点燃的开始的 Cx30 mRNA 的 Overexpression 与各自的起始的蛋白质增加一致。此后,没有变化在点燃期间在蛋白质丰富被发现。关于 Cx32,在概括发作和没有另外的重要变化的获得在点燃期间在 mRNA 和蛋白质丰富被检测以后, mRNA 表示减少了。我们在马头鱼尾的怪兽推测那 Cx32 GJ 通讯的结论不贡献点燃 epileptogenesis。然而,对在马头鱼尾的怪兽的 perivascular 区域局部性的 Cx30 astrocytic 网络是在点燃从周围清除 excitotoxic 分子的开始的 overexpressed。 | Bijan Akbarpour Mohammad Sayyah Vahab Babapour Reza Mahdian Siamak Beheshti Ahmad Reza Kamyab | 2012 | Neuroscience Bulletin2012，28，6： | 1 |
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