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58篇 您的检索式:作者名="BLOME S"
    题名 作者 年代 出处 被引量
1One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients.Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh 2011Hepatobiliary & Pancreatic Diseases International2011,10,4:8
2Development of a highly sensitive real-time RT-PCR protocol for the detection of Classical swine fever virus independent of the 5'untranslated region 显示文摘Leifer I Blome S Beer M 2011Journal of Virological Methods2011,171,1:1
3Characterization of African swine fever virus Caucasus isolate in European wild boars显示文摘Gabriel C Blome S Malogolovkin A 2011Emerg Infect Dis2011,17,12:1
4Transcardiopulmonary vs pulmonary arterial thermodilution methods for hemodynamic monitoring of burned patients 显示文摘Kuntscher MV Blome - Eberwein S Pelzer M 2002J Burn Care Rehabil2002,23,1:1
5High virulence of Afri- can swine fever virus caucasus isolate in European wild boars of all ages显示文摘Blome S Gabriel C Dietze K 2012Emerg Infect Dis2012,18,4:1
6Classical swine fever virus detection:results of a real-time reverse transcription poly- merase chain reaction ring trial conducted in the framework of the European network of excellence for epizootie disease diag- nosis and control显示文摘Hoffmann B Blome S Bonilaufi P et a/ 2011J Vet Diagn Invest2011,23,5:1
7Supplementation of 1% l-glutamine to milk replacer does not overcome the growth depression in calves caused by soy protein concentrate显示文摘Drackley J K Blome R M Bartlett K S 2006J Dairy Sci2006,89,:1
8First assessment of classical swine fever marker vaccine can didate CP7 E2alf for oral immunization of wild boar under field conditions显示文摘Feliziani F Blome S Petrini S Giammarioli M Iscaro C Scveri G Convito L Pietschmann J Beer M De Mia G M 2014Vaccine2014,32,18:1
9Development and validation of aharmonized TaqMan-based triplex real-time RT-PCR protocolfor the quantitative detection of normalized gene expressionprofiles of seven porcine cytokines 显示文摘Petrov A Beer M Blome S 2014PLoS One2014,9,08:1
10Classical swine fever virus in South-Eastern Europe retrospective analysis of the disease situation and molecular epidemiology 显示文摘Blome S Grotha I Moennig V 2010Vet Microbiol2010,146,34:1
11Differentiation of C-strain 'Riems' or CP7 E2alf vaccinated animals from animals infected by classical swine fever virus field strains using real-time RT-PCR显示文摘Leifer I Depner K Blome S 2009Journal of virological methods2009,158,12:1
12Transcardiopul- monary thermal dye versus single thermodilution methods for assessment of intrathoracic blood volume and extravascular lung water in major bum resuscitation显示文摘Kuntscher MV Czermak C Blome - Eberwein S 2003J Bum Care Rehabiol2003,24,:1
13Modern adjuvants do not enhance the efficacy of an inactivated African swine fever virus vaccine preparation显示文摘Blome S Gabriel C Beer M 2014Vaccine2014,32,:1
14Classical swine fe- ver virus in South-Eastern Europere-ospeetive analysis of the disease situation and molecular epidemiology显示文摘Blome S Grotha I Moennig V 2010Vet Micmbiol2010,146,34:1
15Classical swine fever virus in South-eastern Europe retrospective analysis of the disease situation and molecular epidemiology显示文摘Blome S Grotha I Moennig V 2010Vet Microbiol2010,146,34:1
16Enantioselective high-performance liquid chromatography assay of(+)R-and(-)S-alpha-lipoic acid in human plasma显示文摘Niebch G Buehele B Blome J Grieb S 1997Chirality1997,9,1:1
17Pathogenesis of classical swine fever--similarities to viral hemorrhagic fevers:a review显示文摘Lange A Blome S Moennig V 2011Bed Munch Tierarzd Wochenschr2011,124,12:1
18Analysis of spatiotemporal patterns of African swine fever cases in Russian wild boar does not reveal an endemic situation显示文摘Lange M Siemen H Blome S 2015Preventive Veterinary Medicine2015,117,:1
19Development of a highly sensi-tive real-time RT-PCR protocol for the detection of classicalswine virus independent of the 5/ untranslatedregion 显示文摘Leifer I Blome S Beer M 2011TheJournal of Virology Methods2011,171,1:1
20Diagnostic meth- ods for detection of classical swine fever virus - Status quo and new developments 显示文摘GREISER- WILKE I BLOME S MOENNIG V 2007Vaccine2007,25,30:1
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