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7篇 您的检索式:作者名="Ari Le"
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1How does financial literacy impact on inclusive finance?显示文摘Inclusive finance is a core concept of finance that makes various financial products and services accessible and affordable to all individuals and businesses,especially those excluded from the formal financial system.One of the leading forces affecting people’s ability to access financial services in rural areas is financial literacy.This study investigated the impacts of financial knowledge on financial access through banking,microfinance,and fintech access using the Bangladesh rural population data.We employed three econometrics models:logistic regression,probit regression,and complementary log–log regression to examine whether financial literacy significantly affects removing the barriers that prevent people from participating and using financial services to improve their lives.The empirical findings showed that knowledge regarding various financial services factors had significant impacts on getting financial access.Some variables such as profession,income level,knowledge regarding depositing and withdrawing money,and knowledge regarding interest rate highly affected the overall access to finance.The study’s results provide valuable recommendations for the policymaker to improve financial inclusion in the developing country context.A comprehensive and long-term education program should be delivered broadly to the rural population to make a big stride in financial inclusion,a key driver of poverty reduction and prosperity boosting.Morshadul Hasan Thi Le Ariful Hoque 2021Financial Innovation2021,7,1:5
2Cell:癌基因“遗传平衡”或会影响患者对癌症疗法的反应显示文摘进行癌症疗法的选择越来越需要确定肿瘤细胞中是否含有一些特殊突变的癌基因会驱动癌细胞异常生长。并且确定是否癌细胞会对特殊药物耐受或敏感.近日来自加州大学旧金山分校的研究人员就通过研究发现。以常见的癌基因KRAs突变为例。患者对疗法的反应往往会随着肿瘤的不断进化而发生改变。相关研究刊登于国际杂志Cell上。Michael R. Burgess Eugene Hwang Rana Mroue Craig M. Bielski Anica M. Wandler Benjamin J. Huang Ari J. Firestone Amy Young Jennifer A. Lacap Lisa Crocker Saurabh Asthana Elizabeth M. Davis Jin Xu Keiko Akagi Michelle M. Le Beau Qing Li Benjamin Haley David Stokoe Deepak Sampath Barry S. Taylor Marie Evangelista Kevin Shannon 2017现代生物医学进展2017,17,18:2
3The SYNTAX score:an angiographic tool grading the complexity of coronary artery disease显示文摘Georgios S Marie-Angèle MB Arie PK 2005EuroIntervention2005,1,:1
4Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II显示文摘Vasim Farooq David van Klaveren Ewout W Steyerberg Emanuele Meliga Yvonne Vergouwe Alaide Chieffo Arie Pieter Kappetein Antonio Colombo David R Holmes Michael Mack Ted Feldman Marie-Claude Morice Elisabeth St?hle Yoshinobu Onuma Marie-angèle Morel Hector 2013The Lancet2013,,9867:1
5Stenting versus thrombolysis in acute myocardial infarction trial显示文摘Le May MR labinaz M Aries RF 2001JACC2001,37,:1
6Fuel-ion diffusion in shock-driven inertial confinement fusion implosions显示文摘The impact of fuel-ion diffusion in inertial confinement fusion implosions is assessed using nuclear reaction yield ratios and reaction histories.In T3He-gas-filled(with trace D)shock-driven implosions,the observed TT/T3He yield ratio is∼23lower than expected from temperature scaling.InD3He-gas-filled(with trace T)shock-driven implosions,the timing of theD3He reaction history is∼50 ps earlier than those of the DT reaction histories,and average-ion hydrodynamic simulations cannot reconcile this timing difference.Both experimental observations are consistent with reduced T ions in the burn region as predicted by multi-ion diffusion theory and particle-in-cell simulations.Hong Sio Chikang Li Cody E.Parker Brandon Lahmann Ari Le Stefano Atzeni Richard D.Petrasso 2019Matter and Radiation at Extremes2019,4,5:0
7A Th2-score in the tumor microenvironment as a predictive biomarker of response to Bacillus Calmette Guérin in patients with non-muscle invasive bladder carcinoma:A retrospective study显示文摘Intravesical Bacillus Calmette Guerin(BCG)is the gold standard therapy for intermediate/high-risk nonmuscle invasive bladder cancer(NMIBC).However,the response rate is~60%,and 50%of non-responders will progress to muscle-invasive disease.BCG induces massive local infiltration of inflammatory cells(Th1)and ultimately cytotoxic tumor elimination.We searched for predictive biomarker of BCG response by analyzing tumor-infiltrating lymphocyte(TIL)polarization in the tumor microenvironment(TME)in pre-treatment biopsies.Pre-treatment biopsies from patients with NMIBC who received adequate intravesical instillation of BCG(n=32)were evaluated retrospectively by immunohistochemistry.TME polarization was assessed by quantifying the T-Bet+(Th1)and GATA-3+(Th2)lymphocyte ratio(G/T),and the density and degranulation of EPX+eosinophils.In addition,PD-1/PD-L1 staining was quantified.The results correlated with BCG response.In most non-responders,Th1/Th2 markers were compared in pre-and post-BCG biopsies.ORR was 65.6%in the study population.BCG responders had a higher G/T ratio and a greater number of degranulated EPX+cells.Variables combined into a Th2-score showed a significant association with higher scores in responders(p=0.027).A Th2-score cut-off value>48.1 allowed discrimination of responders with 91%sensitivity but lower specificity.Relapse-free survival was significantly associated with the Th2-score(p=0.007).In post-BCG biopsies from recurring patients,TILs increased Th2-polarization,probably reflecting BCG failure to induce a pro-inflammatory status and,thus,a lack of response.PD-L1/PD-1 expression was not associated with the response to BCG.Our results support the hypothesis that a preexisting Th2-polarized TME predicts a better response to BCG,assuming a reversion to Th1 polarization and antitumor activity.GUSTAVO MARTÍN VILLOLDO MARÍA TERESA POMBO MARIANA ARIS JOAQUÍN CHEMI PABLO MANDÓ SUPRIYA NAGARAJU JUAN CAMEAN ADRIÁN BURIONI DEBORAH EGEA MORA AMAT JOSÉLEÓN MELLADO JOSÉMORDOH ALBERTO VILLARONGA MARÍA MARCELA BARRIO 2023Oncology Research2023,31,2:0
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