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		题名	作者	年代	出处	被引量
	1	Characterization and phylogenetic analysis of novel polyene type antimicrobial metabolite producing actinomycetes from marine sediments:Bay of Bengal India显示文摘Objective:To isolate and indentify the promising antimicrobial metabolite producing Streptomyces strains from marine sediment samples from Andraprudesh coast of India.Methods:Antagonistic aetinomycetes were isolated by starch casein agar medium and modified nutrient agar medium with 1%glucose used as a base for primary screening.Significant antimicrobial metabolite producing strains were selected and identified by using biochemical and 16S rDNA level.Minimum inhibitory concentrations of the organic extracts were done by using broth micro dilution method.Results:Among the 210 actinomyeetes,64.3%exhibited activity against Gram positive bacteria,48.5%showed activity towards Cram negative bacteria,38.8%exhibited both Cram positive and negative bacteria and 80.85%isolates revealed significant antifungal activity.However,five isolates AP-5,AP-18,AP-41 and AP-70 showed significant antimicrobial activity.The analysis of cell wall hydrolysates showed the presence of LL-diaminopimelic acid and glycine in all the isolates.Sequencing analysis indicated that the isolates shared 98.5%-99.8%sequence identity to the 16S rDNA gene sequences of the Streptomyces taxons.The antimicrobial substances were extracted using hexane and ethyl acetate from spent medium in which strains were cultivated at 30X for five days.The antimicrobial activity was assessed using broth micro dilution technique.Each of the culture extracts from these five strains showed a typical polyenelike property.The lowest minimum inhibitory concentrations of ethyl acetate extracts against Escherichia coli and Cumularia lunula were 67.5 and 125.0μg/mL,respectively.Conclusions:It can be concluded that hexane and ethyl acetate soluble extracellular products of novel isolates are effective against pathogenic bacteria and fungi.	Valan Arasu M Asha KRT Duraipandiyan V Ignacimuthu S Agastian P	2012	Asian Pacific Journal of Tropical Biomedicine2012，2，10：	5
	2	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis显示文摘	Arasu P Ellis LA Iglesias R	1994	Mol Biochem Parasitol1994，65，：	1
	3	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis 显示文摘	Arasu P Ellis LA Iglesias R	1994	Mol Biocbem Parasitol1994，65，2：	1
	4	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis显示文摘	Arasu P Ellis L A Iglesias R	1994	Mol Biochem Parasitol1994，65，2：	1
	5	New families of binary sequence pairs with two-level and three-level correlation 显示文摘	Peng X P Xu C Q Arasu K T	2012	IEEE Trans Inf Theory2012，58，11：	1
	6	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis显示文摘	Arasu P Ellis LA Iglesial R	1994	Mol Biochem parasitol1994，65，2：	1
	7	Evaluation of endogenous reference genes for real-time PCR quantification of gene expression in A ncylostoma cartinum 显示文摘	Trivedi S Arasu P	2005	Mol Biochem Parasitol2005，143，2：	1
	8	Gene expression profiles associated with the transition to parasitism in Ancylostoma caninum larvae显示文摘	Moser JM Freitas T Arasu P	2005	Mol Biochem Parasitol2005，143，：	1
	9	Molecular analysis of antigenstargeted by protective antibodies in rapid expulsion of Trichinella spiralis显示文摘	Arasu P Ellis L Iglesias R	1994	Mol Biochem Parasitol1994，65，：	1
	10	Tandemly arranged gene clusters of malar- ial parasites that are highly conserved and transcribed 显示文摘	Vaidya AB Arasu P	1987	Mol Biochem Parasit1987，22，23：	1
	11	, Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichindla spiralis 显示文摘	Arasu P Ellis L A Iglesias R	1994	Mol Biochem Parasitol1994，65，：	1
	12	Temporal regulation of lin-14 by the antagonistic action of two other heterochronie genes, lin-4 and lin-28显示文摘	Arasu P Wightman B Ruvkun G	1991	Gene Dev1991，5，10：	1
	13	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis 显示文摘	Arasu P Ellis LA Iglesias R	1994	Mol Biochem Parasitol1994，65，2：	1
	14	Molecular analysis of antigens targeted by protective antibodies in rapid expulsion of Trichinella spiralis 显示文摘	Arasu P Ellis LA Iglesias R	1994	Mol Biochem Parasitol1994，65，2：	1
	15	Molecular analysis of antigens targeted by protective antibodies m rapld expulslon of Trichinella spiralis 显示文摘	Arasu P Ellis L A Iglesias R	1994	Mol Biochem Parasitol1994，65，2：	1

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