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| 1 | Physical exercise in the prevention and treatment of Alzheimer’s disease显示文摘Dementia is one of the greatest global challenges for health and social care in the 21st century.Alzheimer’s disease(AD),the most common type of dementia,is by no means an inevitable consequence of growing old.Several lifestyle factors may increase,or reduce,an individual’s risk of developing AD.Much has been written over the ages about the benefits of exercise and physical activity.Among the risk factors associated with AD is a low level of physical activity.The relationship between physical and mental health was established several years ago.In this review,we discuss the role of exercise(aerobic and resistance)training as a therapeutic strategy for the treatment and prevention of AD.Older adults who exercise are more likely to maintain cognition.We address the main protective mechanism on brain function modulated by physical exercise by examining both human and animal studies.We will pay especial attention to the potential role of exercise in the modulation of amyloid b turnover,inflammation,synthesis and release of neurotrophins,and improvements in cerebral blood flow.Promoting changes in lifestyle in presymptomatic and predementia disease stages may have the potential for delaying one-third of dementias worldwide.Multimodal interventions that include the adoption of an active lifestyle should be recommended for older populations. | Adrian De la Rosa Gloria Olaso-Gonzalez Coralie Arc-Chagnaud Fernando Millan Andrea Salvador-Pascual Consolacion Garcıa-Lucerga Cristina Blasco-Lafarga Esther Garcia-Dominguez Aitor Carretero Angela G.Correas Jose Vina Mari Carmen Gomez-Cabrera | 2020 | Journal of Sport and Health Science2020，9，5： | 32 |
| 2 | Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes. | Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu | 2016 | Fungal Diversity2016，，5： | 2 |
| 3 | How utilizing the genes involved in drought tolerance could tackle the climate change-related food crisis?显示文摘The global population is expected to increase by 10 billion by 2050,the demand for food and water is also likely to increase.Several factors intensify the growing water scarcity,such as inefficient water use in the food value chain and inadequate infrastructure to save water.The changing climate also exacerbates the rising temperature by making the drier areas drier and negatively impacting agriculture production in most parts of the world.A decrease in precipitation has been observed in the tropics and sub-tropics,such as the Sahel region of Southern Africa,the Mediterranean,South Asia,and the Southwest of US since 1970(http://gffzz73fdc6a2db374da3sxqkux5wqf66p6p6k.ffgz.tsg.suse.edu.cn). | Angela Fernando Michael Selvaraj Manabu Ishitani Kazuo Nakashima Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki | 2021 | Molecular Plant2021，14，10： | 1 |
| 4 | Clinical and economic impact of procalcitonin to shorten antimicrobial therapy in septic patients with proven bacterial infection in an intensive care setting显示文摘 | Rodrigo Octavio Deliberato Alexandre R. Marra Paula Rodrigues Sanches Marines Dalla Valle Martino Carlos Eduardo dos Santos Ferreira Jacyr Pasternak Angela Tavares Paes Lilian Moreira Pinto Oscar Fernando Pav?o dos Santos Michael B. Edmond | 2013 | Diagnostic Microbiology & Infectious Disease2013，，3： | 1 |
| 5 | Agreement between IOLMaster 500 and Pentacam HR for keratometry assessment in type 2 diabetic and nondiabetic patients显示文摘AIM:To evaluate inter-device agreement of anterior keratometry obtained by the IOLMaster 500 and Pentacam HR in type 2 diabetic and non-diabetic patients.METHODS:Corneal measurements were sequentially performed in 60 diabetes mellitus(DM)and 48 age and sex-matched controls undergoing cataract surgery.Variables recorded included flat and steep keratometry,mean keratometry(Km),astigmatism magnitude,axis location,JO and J45 components.Bland-Altman plots and intraclass correlation coefficients were used for examination of agreement.Subgroup analyses were performed for astigmatism magnitude,diabetes duration,hemoglobin A1c(HbA1c)levels and diabetic retinopathy(DR)stage.RESULTS:Agreement for Km and astigmatism magnitude were considered good and moderate,with 95%limits of agreement(LoA)of-1.09 to 1.23 diopters(D)and-0.83 to 0.86 D in DM group,respectively;and-0.59 to 0.72 D and-0.98 to 0.75 D in non-DM group,respectively.In contrast,the 95%LoA for corneal axis exceeded the clinically relevant margins in both groups.In the total sample,only 41 eyes(38%)had a smaller than 5-degree difference.Diabetes duration,HbA1c levels and DR stage were not found to significantly affect agreement.Logistic regression showed that higher corneal power(P=0.021)and astigmatism magnitude(P=0.011)were associated with a decreased risk of having a difference in axis location greater than 10-degrees.CONCLUSION:In both groups,IOLMaster and Pentacam agree well for corneal power and moderately for astigmatism.However,axis location disagreement is frequent in eyes with flatter corneas and small amounts of astigmatism. | Joao N Beato Joao Esteves-LeANDro David Reis Rita Matos Manuel Falcao Vítor Rosas Angela Carneiro FernANDo Falcao-Reis | 2020 | International Journal of Ophthalmology(English edition)2020，13，6： | 1 |
| 6 | Pre and post-natal exposure to ambient level of air pollution impairs memory of rats: the role of oxidative stress显示文摘 | Ana C.T. Zanchi Lucas S. Fagundes Fernando Barbosa Rosane Bernardi Claudia Ramos Rhoden Paulo H.N. Saldiva Angela Cristina do Valle | 2010 | Inhalation Toxicology2010，，11： | 1 |
| 7 | A Clearinghouse for Genome-Edited Crops and Field Testing显示文摘Latin America was commonly called'sleeping giant'for its humid tropics and land base relative to its population size.The International Center for Tropical Agriculture(ClAT,by.its Spanish acronym)was initiated in 1967 to serve three important zones-coastal plains,savannahs,and“hot,humid jungles.”In line,the research areas were organized to be fitted as appropriate into these important ecological zones.Over the 50 years,CIAT has been a forerunner in developing and disseminating improved crop varieties and agricultural technologies,including its pioneering approaches in the tropics. | Angela Fernando Michael Selvaraj Paul Chavarriaga Sandra Valdes Joe Tohme | 2021 | Molecular Plant2021，14，1： | 1 |
| 8 | Distribution of the antifungal agents sordarins across filamentous fungi显示文摘 | Francisca Vicente Angela Basilio Gonzalo Platas Javier Collado Gerald F. Bills Antonio González Del Val Jesús Martín José R. Tormo Guy H. Harris Deborah L. Zink Michael Justice Jennifer Nielsen Kahn Fernando Peláez | 2009 | Mycological Research2009，，6： | 1 |
| 9 | Discrimination of organic coffee via Fourier transform infrared–photoacoustic spectroscopy显示文摘 | Fernando Gordillo‐Delgado Ernesto Marín Diego Mauricio Cortés‐Hernández Claudia Mejía‐Morales Angela Janet García‐Salcedo | 2012 | J Sci Food Agric2012，，11： | 1 |
| 10 | Impact of hormonal modulation at proestrus on ovarian responses and uterine gene expression of suckled anestrous beef cows显示文摘Background: This study evaluated the impact of hormonal modulation at the onset of proestrus on ovarian response and uterine gene expression of beef cows.Methods: A total of 172 anestrous beef cows were assigned to one of four groups according to the treatment with estradiol cypionate(ECP) and/or equine chorionic gonadotropin(eCG) [CON(n = 43), ECP(n = 43), eCG(n = 44)and ECP + eCG(n = 42)].Results: ECP-treated cows(ECP and ECP + eCG groups) presented greater occurrence of estrus(44.6% vs. 65.4%; P = 0.01) and pregnancy per AI [47.1% vs. 33.3%; P = 0.07], but similar progesterone(P4) concentration at subsequent diestrus than cows not treated with ECP(CON and eCG groups). Nonetheless, eCG-treated cows(eCG and ECP + eCG groups) presented larger follicle at timed AI(12.6 ± 0.3 vs. 13.5 ± 0.3 mm; P = 0.03), greater ovulation rate(96.5%vs. 82.6%; P = 0.008) and greater P4 concentration at d 6(3.9 ± 0.2 vs. 4.8 ± 0.2 ng/mL; P = 0.001) than cows not treated with eCG(CON and ECP groups). Next, cows with a new corpus luteum 6 d after TAI were submitted to uterine biopsy procedure. Uterine fragments [CON(n = 6), ECP(n = 6)] were analyzed by RNA-Seq and a total of 135 transcripts were differentially expressed between groups(73 genes up-regulated by ECP treatment). Subsequently,uterine samples were analyzed by q PCR(genes associated with cell proliferation). ECP treatment induced greater abundance of PTCH2(P = 0.07) and COL4 A1(P = 0.02), whereas suppressed EGFR(P = 0.09) expression. Conversely, eCG treatment increased abundance of HB-EGF(P = 0.06), ESR2(P = 0.09), and ITGB3(P = 0.05), whereas it reduced transcription of ESR1(P = 0.05). Collectively, supplementation with ECP or eCG at the onset of proestrous of anestrous beef cows influenced ovarian responses, global and specific endometrial gene expression.Conclusion: Proestrus estradiol regulate the endometrial transcriptome, particularly stimulating proliferative activity in the endometrium. | Manoel Francisco de Sá Filho Angela Maria Gonella-Diaza Mariana Sponchiado Marcio Ferreira Mendanha Guilherme Pugliesi Roney dos Santos Ramos Sónia Cristina da Silva Andrade Gustavo Gasparin Luiz Lehmann Coutinho Marcelo Demarchi Goissis Fernando Silveira Mesquita Pietro Sampaio Baruselli Mario Binelli | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 0 |
| 11 | Going deep:Roots,carbon,and analyzing subsoil carbon dynamics显示文摘Agricultural practices currently contribute to the emission of approximately 10%–12%atmospheric greenhouse gasses,with tillage agriculture accelerating soil disruption and carbon dioxide release.Nevertheless,various options exist,such as converting new lands for agriculture,promoting healthier plant-based diets,adopting advanced management technologies,and minimizing food loss.However,these measures alone are insufficient to ensure environmental sustainability within planetary boundaries. | Ezhilmathi Angela Joseph Fernando Michael Selvaraj Yusaku Uga Wolfgang Busch Hunt Bowers Joe Tohme | 2024 | Molecular Plant2024，17，1： | 0 |
| 12 | The power of phenomics:Improving genebank value and utility显示文摘Genebanks are considered the'crown jewels'of research organizations,as they safeguard valuable plant genetic resources and address the emerging challenges posed by climate-related constraints(Anglin et al.,2018).Currently,7.4 million accessions have been conserved in 1750 gene banks worldwide.Of these,only 10%are being used for crop improvement(Commission on Genetic Resources for Food and Agriculture,2010).The limited availability of passport data and the challenge of characterizing trait attributes of accessions at large scale are some of the challenges to relate their true value(Tadesse et al.,2019).Obtaining traits such as agronomic or nutritional characteristics requires extensive field phenotyping and multiple site testing over several seasons.This will create value with accurate evaluation of genotype-by-environmental variation in a given trait.The use of low-cost high-throughput phenotyping(HTP)methods to characterize the genotypic and phenotypic representations of genebank genetic resources,otherwise known as genebank phenomics,will help in understanding crops'potential for use in breeding programs with desirable traits. | Ezhilmathi Angela Joseph Fernando Michael Selvaraj Kioumars Ghamkhar | 2023 | Molecular Plant2023，16，7： | 0 |
| 13 | How Africa Is Promoting Agricultural Innovations and Technologies amidst the COVID-19 Pandemic显示文摘The COVID-19 pandemic has left an indelible mark on Africa's Agribusiness sector.Millions of households whose livelihoods depend on farming are facing a huge food crisis.To mitigate these effects,the African Agricultural Technology Foundation(AATF)gathered a panel of renowned agricultural experts through an interactive webinar themed'Promotion of Agricultural Technologies and Innovations for Agri-Business Resilience in Africa in the Wake of COVID-19',the first in a series of several interactive seminars to be held virtually until the end of December 2020.These seminars will focus on several topics specific to agricultural transformation,which revolve around smallholder farmers in Sub-Saharan Africa(SSA)and aim to help them come out of the cataclysmic effect of COVID-19 and recover their business and livelihoods. | Angela Joseph Fernando | 2020 | Molecular Plant2020，13，10： | 0 |
| 14 | LUCC (Land Use and Cover Change) and the Environmental-Economic Accounts System in Brazil显示文摘 | Rodrigo de Campos Macedo Mauricio Zacharias Moreira Eloisa Domingues Angela Maria Resende Couto Gama Fabio Eduardo de Giusti Sanson Felipe Wolk Teixeira Fernando Peres Dias Femando Yutaka Yamaguchi Luiz Roberto de Campos Jacintho | 2013 | Journal of Earth Science and Engineering2013，3，12： | 0 |
| 15 | Frontline remote sensing tool to locate hidden traits in root and tuber crops显示文摘Root and tuber crops(RTCs)play an important role in alleviating poverty,improving health and nutrition,and providing excellent opportunities for improving the livelihoods of smallholder farmers in countries like sub-Saharan Africa.Starch roots and tubers are edible starch materials that are stored in the subterranean stems,roots(cassava and sweet potatoes),rhizomes(canna and arrow roots),corms(taros and cocoyams),and tubers(potatoes and yams)(Chandrasekara and Kumar,2016). | Ezhilmathi Angela Joseph Fernando Michael Gomez Selvaraj Alfredo Delgado Ismail Rabbi Peter Kulakow | 2022 | Molecular Plant2022，15，10： | 0 |
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