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| 1 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 2 | Educated consumers don't believe artificial meat is the solution to the problems with the meat industry显示文摘The production of in vitro meat by cell culture has been suggested by some scientists as one solution to address the major challenges facing our society. Firstly, consumers would like the meat industry to reduce potential discomfort of animals on modern farms, or even to avoid killing animals to eat them. Secondly, citizens would like meat producers to reduce potential environmental deterioration by livestock and finally, there is a need to reduce world hunger by increasing protein resources while the global population is predicted to grow rapidly. According to its promoters, artificial meat has a potential to make eating animals unnecessary, to reduce carbon footprint of meat production and to satisfy all the nutritional needs and desires of consumers and citizens. To check these assumptions, a total of 817 educated people(mainly scientists and students) were interviewed worldwide by internet in addition to 865 French educated people. We also interviewed 208 persons(mainly scientists) after an oral presentation regarding artificial meat. Results of the three surveys were similar, but differed between males and females. More than half of the respondents believed that 'artificial meat' was feasible and realistic. However, there was no majority to think that artificial meat will be healthy and tasty, except respondents who were in favour of artificial meat. A large majority of the respondents believed that the meat industry is facing important problems related to the protection of the environment, animal welfare or inefficient meat production to feed humanity. However, respondents did not believe that artificial meat will be the solution to solve the mentioned problems with the meat industry, especially respondents who were against artificial meat. The vast majority of consumers wished to continue to eat meat even they would accept to consume less meat in a context of increasing food needs. Only a minority of respondents(from 5 to 11%) would recommend or accept to eat in vitro meat instead of meat produced from farm animals. Despite these limitations, 38 to 47% of the respondents would continue to support research on artificial meat, but a majority of them believed that artificial meat will not be accepted by consumers in the future, except for respondents who were in favour of artificial meat. We speculated that the apparent contradictory answers to this survey expressed the fact that people trust scientists whoare supposed to continuously discover new technologies potentially useful in a long term future for the human beings, but people also expressed concern for their health and were not convinced that artificial meat will be tasty, safe and healthy enough to be accepted by consumers. | Aurélie Hocquette Carla Lambert Clémentine Sinquin Laure Peterolff Zoé Wagner Sarah P F Bonny André Lebert Jean-Franois Hocquette | 2015 | Journal of Integrative Agriculture2015，14，2： | 11 |
| 3 | Cell Therapy Based on Adipose Tissue-Derived Stromal Cells Promotes Physiological and Pathological Wound Healing显示文摘 | T G. Ebrahimian F Pouzoulet C Squiban V Buard M André B Cousin P Gourmelon M Benderitter L Casteilla R Tamarat | 2009 | Arteriosclerosis, Thrombosis, and Vascular Biology2009，，4： | 2 |
| 4 | Genetic ancestry analysis in non-alcoholic fatty liver disease patients from Brazil and Portugal显示文摘AIM:To study the association between genetic ancestry,non-alcoholic fatty liver disease(NAFLD) metabolic characteristics in two cohorts of patients,from Brazil and Portugal. METHODS:We included 131 subjects from Brazil [(n = 45 with simple steatosis(S. Steatosis) and n = 86 with nonalcoholic steatohepatitis(NASH)] and 90 patients from Portugal(n = 66,S. Steatosis; n = 24,NASH). All patients had biopsy-proven NAFLD. In histologic evaluation NAFLD activity score was used to assess histology and more than 5 points defined NASH in this study. Patients were divided into two groups according to histology diagnosis:simple steatosis or non-alcoholic statohepatitis. Genetic ancestry was assessed using real-time polymerase chain reaction. Seven ancestry informative markers(AT3-I/D,LPL,Sb19.3,APO,FYNull,PV92,and CKMM) with the greatest ethnicgeographical differential frequencies(≥ 48%) were used to define genetic ancestry. Data were analyzed using R PROJECTS software. Ancestry allele frequencies between groups were analyzed by GENEPOP onlineand the estimation of genetic ancestry contribution was evaluated by ADMIX-95 software. The 5% alpha-error was considered as significant(P < 0.05). RESULTS:In the Brazilian sample,NASH was significantly more frequent among the elderly patients with diabetes(NASH 56 ± 1.1 years old vs S. Steatosis 51 ± 1.5 years old,P = 3.7 x 10-9),dyslipidemia(NASH 63% vs S. Steatosis 37%,P = 0.009),higher fasting glucose levels(NASH 124 ± 5.2 vs S. Steatosis 106 ± 5.3,P = 0.001) and Homeostatic Model of Assessment index > 2.5 [NASH 5.3(70.8%) vs S. Steatosis 4.6(29.2%) P = 0.04]. In the Portuguese study population,dyslipidemia was present in all patients with NASH(P = 0.03) and hypertension was present in a larger percentage of subjects in the S. Steatosis group(P = 0.003,respectively). The genetic ancestry contribution among Brazilian and Portuguese individuals with NASH was similar to those with S. Steatosis from each cohort(Brazilian cohort:P = 0.75; Portuguese cohort:P = 0.97). Nonetheless,the genetic ancestry contribution of the Brazilian and Portuguese population were different,and a greater European and Amerindian ancestry contribution was detected in the Portuguese population while a higher African genetic ancestry contribution was observed in Brazilian population of both NASH and S. Steatosis groups.CONCLUSION:There was no difference between the genetic ancestry contribution among Brazilian and Portuguese individuals with NASH and S. Steatosis from each cohort. | Lourianne Nascimento Cavalcante Jose Tadeu Stefano Mariana V Machado Daniel F Mazo Fabiola Rabelo Kiyoko Abe Sandes Flair Jose Carrilho Helena Cortez-Pinto Andre Castro Lyra Claudia P de Oliveira | 2015 | World Journal of Hepatology2015，7，10： | 2 |
| 5 | Large-scale portfolio optimization 显示文摘 | Andre F P | 1984 | Manage- ment Science1984，31，10： | 1 |
| 6 | Strategic quality competition and the porter hypothesis 显示文摘 | Andre J F Gonzalez P | 2009 | Journal of Environmental Economics and Management2009，57，6： | 1 |
| 7 | Analysis of 13000 unique citrus clusters associated with fruit quality ,production and salinity tolerance显示文摘 | TEROL J CONESA A COLMENERO J CERCOS M TADEO F AGUSTI J ALOS E ANDRES F SOLER G BRUMOS J IGLESIAS D GOTZ S LEGAZ F ARGOIUT X COURTOIS B OLLITRAULT P DOSSART C WINCKER P MORILLON R TALON M | 2007 | BMC Genomics2007，8，： | 1 |
| 8 | Electrical field in the resistivity me- dium (slag) of the ESR process: influence on ingot production and quality 显示文摘 | Medina S F Andres M P | 1987 | Ironmaking and Steelmaking1987，14，3： | 1 |
| 9 | Preclinical characterization of 1-7F9,a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells显示文摘 | Romagne F Andre P Spee P | 2009 | Blood2009，114，13： | 1 |
| 10 | Adjustable EDFA gaine qualization filter for DWDM channels based on a single LPG excit- ed by flexural acoustic waves 显示文摘 | Marques Carlos A F Oliveira Roberson A Pohl Alex- andre A P | 2012 | Optics Communica- tions2012，285，18： | 1 |
| 11 | Rate coefficient for reaction SiO+Si2O2 at T=10-1 000 K显示文摘 | André S P Francisco C A Alberico B F | 2006 | J Phys Chem A2006，110，13： | 1 |
| 12 | Wurmian deglaciation of western Lake Geneva (Switzerland) based on seismic stratigraphy显示文摘 | Julien F Stephanie G Andre P | 2011 | Quaternary Science Reviews2011，30，3： | 1 |
| 13 | Effect of biomass particle size and air superficial velocity on the gasification process in a downdraft fixed bed gasifier:An experimental and modelling study显示文摘 | Tinaut Francisco V Melgar Andrés Pérez Juan F | | 0，，11： | 1 |
| 14 | Phase Ⅲ,randomized,double-blind,placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab-resistant,advanced breast cancer (BOLERO-3)显示文摘 | O' Regan R Ozguroglu M Andre F Toi M Jerusalem G Wilks S Isaacs C Xu B Masuda N Arena FP Yardley D Yap YS Mukhopadhyay P Douma S El-Hashimy M Taran T Sahmoud T Lebwohl D Gianni L | | 0，，15： | 1 |
| 15 | Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection显示文摘 | Andrés F Daeui P Jong B | | 0，，： | 1 |
| 16 | Impact of chemoradiotherapy after disease control with chemotherapy in locally advanced pancreatic adenocarcinoma in GERCOR phase Ⅱ and Ⅲ studies 显示文摘 | Huguet F Andre T Hammel P | 2007 | J Clin Oncol2007，25，3： | 1 |
| 17 | Effect of salt stress on antioxidative enzymes and lipid peroxidation in leaves and roots of salt-tolerant and salt-sensitive maize genotypes显示文摘 | ANDR(E) A D N A JOS(E)T P JOAOUIM E F | 2006 | Environmental and Experimental Botany2006，56，： | 1 |
| 18 | Proteome analysis of Acetobacter pasteurianus during acetic acid fermentation显示文摘 | Andrés-Barrao C Saad MM Chappuis ML Boffa M Perret X Pérez RO Barja F | | 0，，06： | 1 |
| 19 | A hybrid meta-lear-ning architecture for multi-objective optimization of SVM parameters显示文摘 | Péricles B C Ricardo B C André P L F | 2014 | Neurocomputing2014，143，2： | 1 |
| 20 | Molecular characteriza- tion of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array显示文摘 | Andre F Job B Dessen P | 2009 | Clinical Can- cer Research2009，15，2： | 1 |
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