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| 1 | Functional Recovery After Acute Myocardial Infarction显示文摘 | Robin Nijveldt Aernout M. Beek Alexander Hirsch Martin G. Stoel Mark B.M. Hofman Victor A.W.M. Umans Paul R. Algra Jos W.R. Twisk Albert C. van Rossum | 2008 | Journal of the American College of Cardiology2008，，3： | 1 |
| 2 | Long-term outcome after an early invasive versus selective invasive treatment strategy in patients with non-ST-elevation acute coronary syndrome and elevated cardiac troponin T (the ICTUS trial): a follow-up study显示文摘 | Alexander Hirsch Fons Windhausen Jan GP Tijssen Freek WA Verheugt Jan Hein Cornel Robbert J de Winter | 2007 | The Lancet . 2007 (9564)2007，，9564： | 1 |
| 3 | Relation Between the Assessment of Microvascular Injury by Cardiovascular Magnetic Resonance and Coronary Doppler Flow Velocity Measurements in Patients With Acute Anterior Wall Myocardial Infarction显示文摘 | Alexander Hirsch Robin Nijveldt Joost D.E. Haeck Aernout M. Beek Karel T. Koch José P.S. Henriques Rene J. van der Schaaf Marije M. Vis Jan Baan Robbert J. de Winter Jan G.P. Tijssen Albert C. van Rossum Jan J. Piek | 2008 | Journal of the American College of Cardiology2008，，23： | 1 |
| 4 | Pulse pressure variation does not reflect stroke volume variation in mechanically ventilated rats with lipopolysaccharide‐induced pneumonia显示文摘 | Thomas GV Cherpanath Lonneke Smeding Wim K Lagrand Alexander Hirsch Marcus J Schultz Johan AB Groeneveld | 2014 | Clin Exp Pharmacol Physiol2014，，1： | 1 |
| 5 | Techniques for can- cellation of interfering multiple reflections in terahertz time- domain measurements 显示文摘 | Hirsch O Alexander P Gladden L F | 2008 | Microelectronics Journal2008，39，： | 1 |
| 6 | A proinflammatory monocyte response is associated with myocardial injury and impaired functional outcome in patients with ST-segment elevation myocardial infarction显示文摘 | Anja M. van der Laan Alexander Hirsch Lourens F.H.J. Robbers Robin Nijveldt Ingrid Lommerse Ronak Delewi Pieter A. van der Vleuten Bart J. Biemond Jaap Jan Zwaginga Wim J. van der Giessen Felix Zijlstra Albert C. van Rossum Carlijn Voermans C. Ellen van d | 2012 | American Heart Journal2012，，1： | 1 |
| 7 | Long-term outcome after an early invasive versus selective invasive treatment strategy in patients with non-ST-elevation acute coronary syndrome and elevated cardiac troponin T (the ICTUS trial): a follow-up study显示文摘 | Alexander Hirsch Fons Windhausen Jan GP Tijssen Freek WA Verheugt Jan Hein Cornel Robbert J de Winter | 2007 | The Lancet2007，，9564： | 1 |
| 8 | Limitations of Quantitative Blush Evaluator(QuBE)as myocardial perfusion assessment method on digital coronary angiograms显示文摘Background and Aim: Quantitative Blush Evaluator (QuBE) is a software application that allows quantifyingmyocardial perfusion in coronary angiograms after a percutaneous coronary intervention. QuBE has somelimitations such as the application of a crude filter to remove large scale structures and the absence of correctionfor cardiac motion. This study investigates the extent of these limitations and we hypothesize that enhancedimage analysis methods can provide improvements.Methods: We calculated QuBE scores of 117 patients from the HEBE Trial and determined its association withthe Myocardial Blush Grade (MBG) score. Accuracy of large-structure removal is qualitatively assessed forvarious sizes of a median filter. The influence of cardiac motion was evaluated by comparing the blush curveand QuBE score of the native QuBE with manually motion-corrected QuBE for 40 patients. The effect ofdifferent kernel sizes and motion correction to a potential improvement of the association between QuBE scoreand MBG was studied.Results: In our population, there was no significant association between QuBE score and MBG (p = 0.14).Median filters of various kernel sizes were unable to remove large structure related noise. Variations in filtersand cardiac movement correction did not result in an improvement in the association with MBG scores(observer 1: p = 0.66;observer 2: p = 0.72).Conclusions: There was no significant association of QuBE with MBG scores in our population, whichsuggests that QuBE is not suitable for a quantitative assessment of myocardial perfusion. Alternative kernelsizes for the large structure removal filter and cardiac motion correction did not improve QuBE performance.Relevance for patients: Further improvements of QuBE to overcome its inherent limitations are necessary inorder to establish QuBE as a reliable myocardial perfusion assessment method. | Haryadi Prasetya Marcel A.M.Beijk Praneeta R.Konduri Thabiso Epema Alexander Hirsch Pim van der Harst Ed van Bavel Bas A.J.M.de Mol Henk A.Marquering | 2017 | Journal of Clinical & Translational Research2017，3，4： | 0 |
| 9 | 破裂和未破裂颅内动脉瘤栓塞治疗实践标准显示文摘弹簧圈栓塞最初被设计并经美国食品药品监督管理局批准用于治疗显微外科手术夹闭风险高的脑动脉瘤,但目前该方法越来越被认为是颅内动脉瘤的一线治疗方法。动脉瘤血管内治疗技术已有长足进步,新器材的研发使得以前因血管解剖结构复杂而无法填塞的动脉瘤也得以治疗,从而扩大了血管内治疗的适应证。而且,血管内弹簧圈栓塞已成为当前动脉瘤血管内治疗的主流方法;医学文献证明,在特定患者人群中,弹簧圈栓塞的转归优于外科手术夹闭。最近的一份美国心脏协会(AmericanHeartAssociation,AHA)科学声明指出,对于适合治疗的脑动脉瘤,不论是血管内栓塞还是显微外科手术夹闭,均为破裂动脉瘤I级推荐治疗方法和未破裂动脉瘤的11a级推荐治疗方法。在这两组患者中,治疗利大于弊。一个在血管显微神经外科、神经重症监护和介入神经外科方面有着丰富经验的多学科团队最有利于对颅内动脉瘤的处理实施最佳的技术。神经血管联合写作组此前已发表过一份联合声明,提出了有关脑血管介入治疗的培训和认证的推荐意见。 | Athos Patsalides Ketan R Bulsara Daniel P Hsu Todd Abruzzo Sandm Narayanan Mahesh V Jayaraman Gary Duckwiler Richard Paul Klucznik Michael Kelly Joshua A Hirsch Don Heck Jeffery Stmshine Don Frei Michael J Alexander Huy M Do Philip M Meyers 邱忠明(译) 张君(译) 徐格林(译) | 2013 | 国际脑血管病杂志2013，21，6： | 0 |
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