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| 1 | Genome resequencing and transcriptome profiling reveal structural diversity and expression patterns of constitutive disease resistance genes in Huanglongbing-tolerant Poncirus trifoliata and its hybrids显示文摘Huanglongbing(HLB)is the most destructive bacterial disease of citrus worldwide.While most citrus varieties are susceptible to HLB,Poncirus trifoliata,a close relative of Citrus,and some of its hybrids with Citrus are tolerant to HLB.No specific HLB tolerance genes have been identified in P.trifoliata but recent studies have shown that constitutive disease resistance(CDR)genes were expressed at much higher levels in HLB-tolerant Poncirus hybrids and the expression of CDR genes was modulated by Candidatus Liberibacter asiaticus(CLas),the pathogen of HLB.The current study was undertaken to mine and characterize the CDR gene family in Citrus and Poncirus and to understand its association with HLB tolerance in Poncirus.We identified 17 CDR genes in two citrus genomes,deduced their structures,and investigated their phylogenetic relationships.We revealed that the expansion of the CDR family in Citrus seems to be due to segmental and tandem duplication events.Through genome resequencing and transcriptome sequencing,we identified eight CDR genes in the Poncirus genome(PtCDR1-PtCDR8).The number of SNPs was the highest in PtCDR2 and the lowest in PtCDR7.Most of the deletion and insertion events were observed in the UTR regions of Citrus and Poncirus CDR genes.PtCDR2 and PtCDR8 were in abundance in the leaf transcriptomes of two HLB-tolerant Poncirus genotypes and were also upregulated in HLB-tolerant,Poncirus hybrids as revealed by real-time PCR analysis.These two CDR genes seem to be good candidate genes for future studies of their role in citrus-CLas interactions. | Nidhi Rawat Brajendra Kumar Ute Albrecht Dongliang Du Ming Huang Qibin Yu Yi Zhang Yong-Ping Duan Kim D Bowman Fred G Gmitter Jr Zhanao Deng | 2017 | Horticulture Research2017，4，1： | 5 |
| 2 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 4 |
| 3 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘 | M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D’Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia | 2008 | Ultraschall in Med2008，，01： | 4 |
| 4 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet . 2001 (9286)2001，，9286： | 4 |
| 5 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | 2001 (9286)2001，，9286： | 4 |
| 6 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘 | M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D'Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia | 2008 | Ultraschall in Med2008，，01： | 3 |
| 7 | Comparison between UV spectroscopy and nirs to assess humification process during sewage sludge and green wastes co-composting显示文摘 | Remy Albrecht Jean Le Petit Gérard Terrom Claude Périssol | 2010 | Bioresource Technology2010，，6： | 2 |
| 8 | Comparative transcriptome analysis during early fruit development between three seedy citrus genotypes and their seedless mutants显示文摘Identification of genes with differential transcript abundance(GDTA)in seedless mutants may enhance understanding of seedless citrus development.Transcriptome analysis was conducted at three time points during early fruit development(Phase 1)of three seedy citrus genotypes:Fallglo(Bower citrus hybrid(Citrus reticulata×C.reticulata×C.paradisi)×Temple(C.reticulata×C.sinensis)),grapefruit(C.paradisi),Pineapple sweet orange(C.sinensis),and their seedless mutants.Seed abortion in seedless mutants was observed at 26 days post anthesis(Time point 2).Affymetrix transcriptomic analysis revealed 359 to 1077 probe sets with differential transcript abundance in the comparison of seedless versus seedy fruits for each citrus genotypes and time points.The GDTA identified by 18 microarray probe sets were validated by qPCR.Hierarchical clustering analysis revealed a range of GDTA associated with development,hormone and protein metabolism,all of which may reflect genes associated with seedless fruit development.There were 14,9 and 12 genes found exhibiting similar abundance ratios in all three seedless versus seedy genotype comparisons at time point 1,2 and 3,respectively.Among those genes were genes coding for an aspartic protease and a cysteine protease,which may play important roles in seedless fruit development.New insights into seedless citrus fruit development may contribute to biotech approaches to create seedless cultivars. | Shujian Zhang Qingchun Shi Ute Albrecht Robert G Shatters Jr Ric Stange Greg McCollum Shuo Zhang Chengming Fan Ed Stover | 2017 | Horticulture Research2017，4，1： | 2 |
| 9 | Expression of the receptor protein tyrosine kinase myk-1/htk in normal andmalignant mammary epithelium 显示文摘 | Berclaz G Andres AC Albrecht D | 1996 | Biochem Biophys ResCommun1996，226，3： | 1 |
| 10 | Novel molecular and cellular strategies in cancer therapy 显示文摘 | Kohler G Albrecht B Fisch P | 1998 | In Vivo1998，12，1： | 1 |
| 11 | Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation显示文摘 | Breier G Albrecht U Sterrer S | 1992 | Development1992，114，2： | 1 |
| 12 | Predictive microbial biochemistry-from molecular fossils to procaryotic membranes显示文摘 | Ourisson G Albrecht P Rohmer M | 1982 | Trends in Biochemical Sciences1982，7，： | 1 |
| 13 | Dicnamine-mediated in- verse-electron-demand hetero-Diels-Alder reaction by using an enanti- oselective H-bond-directing strategy显示文摘 | Albrecht L Dickmeiss G Weise C F | 2012 | Angew Chem Int Ed Engl2012，51，13： | 1 |
| 14 | The Amino-Acid Sequence of Bovine Glutathione Peroxidase显示文摘 | Wolfgang A. GüNZLER Gerd J. STEFFENS Adelbert GROSSMANN Sung-Man A. KIM Fritz ?TTING Albrecht WENDEL Leopold FLOHé | 2009 | Hoppe-Seyler′s Zeitschrift für physiologische Chemie2009，，1： | 1 |
| 15 | Plasma Resonance Enhancement of Raman Scattering by Pyridine Adsorbed on Silver or Gold Sol Particles of Size Comparable to the Excitation Wavelength显示文摘 | CREIGHTON J A BLATCHFORD C G ALBRECHT M G | 1979 | J Chem Soc1979，75，： | 1 |
| 16 | Acquired neuromyoniaand peripheral neuropathy in a patient with Hodgkin,s disease 显示文摘 | Lahrmann H Albrecht G Drlicek M | 2001 | Muscle Nerve2001，24，： | 1 |
| 17 | Asymmetric organocata- lyric formal -cycloadditions via bifunctional H-bond directing di- enamine catalysis显示文摘 | Albrecht L Dickmeiss G Ceus-Acosta F | 2012 | J Am Chem Soc2012，154，5： | 1 |
| 18 | ORION:Clearing near-earth space debris using a 20 kW,530 nm,earth-based,re- petitively pulsed laser显示文摘 | Phipps C R Albrecht G Friedman H | 1996 | Laser and Particle Beams1996，14，1： | 1 |
| 19 | Molecular mechanisms of lymphangiogen- esis in development and cancer 显示文摘 | Albrecht I Christofori G | 2011 | Int J Dev Biol2011，55，45： | 1 |
| 20 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘 | M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D’Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia | 2008 | Ultraschall in Med2008，，01： | 1 |
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