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1Big data storage technologies: a survey显示文摘对于容量快速增长、日趋多元化的大数据,业界亟需开发可行性更好的存储工具。为满足大数据存储需求,存储机制已经形成从传统数据管理系统到No SQL技术的结构化转移。然而,目前可用的大数据存储技术无法为持续增长的异构数据提供一致、可扩展和可用的解决方案。在科学实验、医疗保健、社交网络和电子商务等实际应用中,存储是大数据分析的第一步。截至目前,亚马逊、谷歌和阿帕奇等公司形成了大数据存储方案的行业标准,但尚未有关于大数据存储技术性能和容量提升的深入调查和文献报告。本文旨在对目前可用于大数据的最先进的存储技术进行全面调查,提供了一个明确的大数据存储技术分类方法,以帮助数据分析师和研究人员了解和选择更适合其需求的存储机制。我们使用布鲁尔的CAP定理比较和分析了现有存储方法,评估了不同存储架构的性能,讨论了存储技术的意义、应用及其对其他类别数据的支持。为了加快部署可靠和可扩展的存储系统,文中还突出了未来研究面临的几个挑战。Aisha SIDDIQA Ahmad KARIM Abdullah GANI 2017Frontiers of Information Technology & Electronic Engineering2017,18,8:15
2旱区农业雨水资源利用与生态系统可持续性:2013干旱农业和生态系统可持续性国际会议综述显示文摘随着全球气候变化的日益凸显,旱区农业和生态系统可持续性发展越来越受到世界各国政府和生态学家的关注。本文综述了2013年10月14—18日在兰州大学举行的干旱农业和生态系统可持续性国际会议全部28场学术报告,围绕'旱区雨水资源高效利用与生态系统可持续管理'的主题,分别从干旱农业面临的机遇和挑战、雨水资源高效利用、旱区生物多样性保护、生态信息系统构建、生态系统可持续管理和加强发展中国家之间的国际合作等几个方面进行了总结。文章最后围绕生态系统圈层管理理论,总结了最近几年在旱区农业水资源利用和生态系统管理方面的最新进展,构建了生态保育和农业生产之间的耦合关系图,为气候变化下旱区粮食安全、农户生计改善、生态系统可持续管理和社会经济协调发展提供理论依据。王慧莉 田涛 王建永 Asfa Batool 赵旭喆 莫非 Nudrat Aisha Akram 熊友才 2014生态学杂志2014,33,11:12
3猫尾木挥发油对美洲斑潜蝇产卵驱避作用研究(英文)显示文摘采用室内生物测定和电生理学的方法研究了猫尾木挥发油对美洲斑潜蝇产卵驱避作用以及美洲斑潜蝇对该挥发油的行为反应和触角电位活性.生物测定结果表明,每棵豆苗施用1~5μL挥发油,大部分处理的落卵量明显低于对照,其中5μL剂量效果最好,干扰作用指数(IIPC)和驱避率分别为0.289、55.14%.这表明挥发油对美洲斑潜蝇具有明显的产卵驱避作用.四臂嗅觉仪测试中对挥发油的第一选择率明显较低,处理的停留时间大部分低于对照,进入次数仅在250mL/min流量时处理明显降低.雌雄虫对挥发油的嗅觉反应无差异.美洲斑潜蝇对挥发油表现明显的触角电位活性,且随着挥发油浓度增大而增大.触角电位活性与挥发油量之间的关系符合模型Y=43.414e0.3691X.应用GC—MS分离出猫尾木挥发油主要含有21种化合物,其中邻苯二甲酸二丁酯含量最高,占56.55%,其次为邻苯二甲酸二乙基己酯和1-壬烯-3-醇,分别占9.8%和6.64%.AISHA Habita 永跃 曾玲 2007华南农业大学学报2007,28,1:6
4多孔介质中热层滞流中辐射效应和均相–非均相反应的熔化传热(英文)显示文摘本文研究了不同厚度多孔介质中的饱和热层滞点流的熔化传热。进一步研究了均相–非均相反应和辐射效应对传热性能的影响。熔融传热和均相反应现象在金属纯化、焊接工艺、电渣熔炼、生化系统、催化和工业中得到了广泛应用。利用同伦过程给出了问题的收敛解。讨论了几个相关参数,速度、热场和浓度分布。本文还描述了摩擦系数和Nusselt数的图解。反应物的浓度由于非均相和均相反应参数强度的变化而降低。由于熔融现象的存在,在较高的辐射参数下,流体温度下降。M.JAVED M.FAROOQ S.AHMAD Aisha ANJUM 2018Journal of Central South University2018,25,11:4
5Trichoderma-Induced Improvement in Growth, Photosynthetic Pigments, Proline, and Glutathione Levels in Cucurbita pepo Seedlings under Salt Stress显示文摘Salt stress is one of the major abiotic stress in plants.However,traditional approaches are not always efficient in conferring salt tolerance.Experiments were conducted to understand the role of Trichoderma spp.(T.harzianum and T.viride)in growth,chlorophyll(Chl)synthesis,and proline accumulation of C.pepo exposed to salinity stress.There were three salt stress(50,100,and 150 mM NaCl)lavels and three different Trichoderma inoculation viz.T.harzianum,T.viride,and T.harzianum+T.viride.Salt stress significantly declined the growth in terms of the shoot and root lengths;however,it was improved by the inoculation of Trichoderma spp.C.pepo inoculated with Trichoderma exhibited increased synthesis of pigments like chl a,chl b,carotenoids,and anthocyanins under normal conditions.It was interesting to observe that such positive effects were maintained under salt-stressed conditions,as reflected by the amelioration of the salinity-mediated decline in growth,physiology and antioxidant defense.The inoculation of Trichoderma spp.enhanced the synthesis of proline,glutathione,proteins and increased the relative water content.In addition,Trichoderma inoculation increased membrane stability and reduced the generation of hydrogen peroxide.Therefore,Trichoderma spp.can be exploited either individually or in combination to enhance the growth and physiology of C.pepo under saline conditions.Mona H.Soliman Taghreed S.Alnusaire Nessreen FAbdelbaky Aisha A.M.Alayafi Mirza Hasanuzzaman Mohamed M.Rowezak Mohamed El-Esawi Amr Elkelish 2020Phyton-International Journal of Experimental Botany2020,89,3:4
6Effect of glycyrrhizic acid and 18β-glycyrrhetinic acid on the differentiation of human umbilical cord-mesenchymal stem cells into hepatocytes显示文摘BACKGROUND End-stage liver disease is a global health complication with high prevalence and limited treatment options.Cell-based therapies using mesenchymal stem cells(MSCs)emerged as an alternative approach to support hepatic regeneration.In vitro preconditioning strategies have been employed to strengthen the regenerative and differentiation potential of MSCs towards hepatic lineage.Chemical compounds of the triterpene class;glycyrrhizic acid(GA)and 18β-glycyrrhetinic acid(GT)possess diverse therapeutic properties including hepatoprotection and anti-fibrosis characteristics.They are capable of modulating several signaling pathways that are crucial in hepatic regeneration.Preconditioning with hepato-protective triterpenes may stimulate MSC fate transition towards hepatocytes.AIM To explore the effect of GA and GT on hepatic differentiation of human umbilical cord-MSCs(hUC-MSCs).METHODS hUC-MSCs were isolated and characterized phenotypically by flow cytometry and immunocytochemistry for the expression of MSC-associated surface molecules.Isolated cells were treated with GA,GT,and their combination for 24 h and then analyzed at three time points;day 7,14,and 21.qRT-PCR was performed for the expression of hepatic genes.Expression of hepatic proteins was analyzed by immunocytochemistry at day 21.Periodic acid Schiff staining was performed to determine the functional ability of treated cells.RESULTS The fusiform-shaped morphology of MSCs in the treatment groups in comparison with the untreated control,eventually progressed towards the polygonal morphology of hepatocytes with the passage of time.The temporal transcriptional profile of preconditioned MSCs displayed significant expression of hepatic genes with increasing time of differentiation.Preconditioned cells showed positive expression of hepatocyte-specific proteins.The results were further corroborated by positive periodic acid Schiff staining,indicating the presence of glycogen in their cytoplasm.Moreover,bi-nucleated cells,which is the typical feature of hepatocytes,were also seen in the preconditioned cells.CONCLUSION Preconditioning with glycyrrhizic acid,18β-glycyrrhetinic acid and their combination,successfully differentiates hUC-MSCs into hepatic-like cells.These MSCs may serve as a better therapeutic option for degenerative liver diseases in future.Abiha Fatima Tuba Shakil Malick Irfan Khan Aisha Ishaque Asmat Salim 2021World Journal of Stem Cells2021,13,10:3
7Gastric endoscopic submucosal dissection as a treatment for early neoplasia and for accurate staging of early cancers in a United Kingdom Caucasian population显示文摘AIM To investigate the efficacy of endoscopic submucosal dissection(ESD) at diagnosing and treating superficial neoplastic lesions of the stomach in a United Kingdom Caucasian population.METHODS Data of patients treated with or considered for ESD at a tertiary referral center in the United Kingdom were retrieved for a period of 2 years(May 2015 to June 2017) from the electronic patient records of the hospital. Only Caucasian patients were included. Primary outcomes were curative resection(CR) and were defined as ESD resections with clear horizontal and vertical margin and an absence of lympho-vascular invasion, poor differentiation and submucosal involvement on histological evaluation of the resected specimen. Secondary end-points were reversal of dysplasia at 12 mo endoscopic follow-up and/or at the latest follow up. Change in histological diagnosis pre and post ESD was also analysed.RESULTS Twenty-four patients were initially identified with intention to treat. 19 patients were eligible after mapping gastroscopy and ESD was attempted on a total of 25 ESD lesions, 4 of which failed and had to be aborted mid-procedure. Out of 21 ESD performed, en-bloc resection was achieved in 71.4% of cases. Resection was considered complete on endoscopy in 90.5% of cases compared to only 38.1% on histology. A total of 6 resections were considered curative(28%), 5 noncurative(24%) and 10 indefinite for CR or non-CR(24%). ESD changed the histological diagnosis in 66.6% of cases post ESD. Endoscopic follow-up in the 'indefinite' group and CR group showed that 50% and 80% of patients were clear of dysplasia at the latest follow-up respectively; 2 cases of recurrence were observed in the 'indefinite'group. Survival rate for the entire cohort was 91.7%.CONCLUSION This study provides early evidence for the efficacy of ESD as a therapeutic and diagnostic intervention in Caucasian populations and supports its application in the United Kingdom.Aisha Sooltangos Matthew Davenport Stephen McGrath Jonathan Vickers Siba Senapati Kurshid Akhtar Regi George Yeng Ang 2017World Journal of Gastrointestinal Endoscopy2017,9,12:3
8Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier显示文摘More than 40%of HIV infections occur via female reproductive tract(FRT)through heterosexual transmission.Epithelial cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexually transmitted pathogens.These sentient cells recognize and respond to external stimuli by induction of a range of carefully balanced innate immune responses.Previously,we have shown that in response to HIV-1 gp120,the genital epithelial cells(GECs)from upper reproductive tract induce an inflammatory response that may facilitate HIV-1 translocation and infection.In this study,we report that the endometrial and endocervical GECs simultaneously induce biologically active interferon-β(IFNβ)antiviral responses following exposure to HIV-1 that act to protect the epithelial tight junction barrier.The innate antiviral response was directly induced by HIV-1 envelope glycoprotein gp120 and addition of gp120 neutralizing antibody inhibited IFNβproduction.Interferon-βwas induced by gp120 in upper GECs through Toll-like receptor 2 signaling and required presence of heparan sulfate on epithelial cell surface.The induction of IFNβwas dependent upon activation of transcription factor IRF3(interferon regulatory factor 3).The IFNβwas biologically active,had a protective effect on epithelial tight junction barrier and was able to inhibit HIV-1 infection in TZM-bl indicator cells and HIV-1 replication in T cells.This is the first report that recognition of HIV-1 by upper GECs leads to induction of innate antiviral pathways.This could explain the overall low infectivity of HIV-1 in the FRT and could be exploited for HIV-1 prophylaxis.Aisha Nazli Sara Dizzell Muhammad Atif Zahoor Victor H Ferreira Jessica Kafka Matthew William Woods Michel Ouellet Ali A Ashkar Michel J Tremblay Dawn ME Bowdish Charu Kaushic 2019Cellular & Molecular Immunology2019,16,2:2
9具有二元化学反应和活化能的压缩流体的磁流体动力学(英文)显示文摘研究了在外加磁场作用下,黏性流体在压缩通道中的运动规律。热量和质量传输过程涉及温度依赖的二元化学反应和修正的Arrhenius活化能函数理论,但是该理论尚未揭示挤压流动机理。在无滑移壁边界条件下,流场、热场和质量场通过无量纲、高度非线性的常微分方程来控制。采用一种收敛性稳定的解析方法求解边值问题。对各种新出现参数的流速场、温度场和流体浓度分布的图进行了详细的研究,获得了表面摩擦、Nusselt和Sherwood数并以图表形式表现。结果表明,流体温度随着占主导地位的无量纲反应速率σ和活化能E的增加而升高。然而,σ和E的增加随着流体浓度的增加而下降。当前研究应用于许多工程和工业过程包括聚合物工业、压缩和注塑成型、润滑系统、纸张的生产、塑料薄膜的成型。在化学工程和地热领域,可以利用磁场来控制核冷却反应、核或化学系统、双分子反应、生化过程和导电聚合物流动。在这些应用的推动下,此研究已得到发展。S.AHMAD M.FAROOQ N.A.MIR Aisha ANJUM M.JAVED 2019Journal of Central South University2019,26,5:2
10GC/GCMS analysis of the petroleum ether and dichloromethane extracts of Moringa oleifera roots显示文摘Objective:To explore the phytochemical constituents from petroleum ether and diehloromethane extracts of Moringa oleifera(M.oleufera)roots using GC/GC—MS.Methods:A total of 5.11 kg fresh and undried crashed root of M.oleifera were cut into small pieces and extracted with petroleum ether and diehloromethane(20 L.each) at room temperature for 2 d.The concentrated extracts were subjected to their GC—MS analysis.Results:The GC-MS analysis of the petroleum ether and diehloromethane extracts of M.oleifern roots,which showed promising biological activities,has resulted in the identification 102 compounds.These constituents belong to 15 classes of compounds including hydrocarbons,fatty acids,esters,alcohols,isolhioeyanate.thiocyanale,pyrazine,aromalics.alkamides.cyanides,steroids,halocompounds.urea and N-hydroxyimine derivatives,unsaturated alkenamides.alkyne and indole.GC/GC-MS studies on petroleum ether extraet of the roots revealed that it contained 39 compounds,belonging to nine classes.Cyclooctasulfur S8 has been isolated as a pure compound from the extract.The major compounds identified from petroleum ether extract were trans-13-clocosene(37.9%).nonacosane(32.6%).cycloartenol(28.6%) nonadecanoic acid(13.9%) and cyclooctasulfur S8(13.9%).Dichloromethane extract of the roots was composed of 63 compounds of which nasimizinol(58.8%) along with oleic acid(46.5%),N—benzyl-N-(7—cyanato heptanamide(38.3%),N—benzyl-N—(1—chlorononyl) amide(30.3%),bis[3—benzyl prop-2-ene]-1-one(19.5%) and N.N-dibeuzyl—2-ene pent 1.5—diamide(11.6%) were the main constituents.Conclusions:This study helps to predict the formula and structure of active molecules which can be used as drugs.This result also enhances the traditional usage of M.oleifera which possesses a number of bioactive compounds.Shaheen Faizi saima sumbul Muhammed Ali Versiani Rubeena Saleem Aisha Sana Hira Siddiqui 2014Asian Pacific Journal of Tropical Biomedicine2014,4,8:2
11Primary epithelial tumours of the appendix in a black population:A review of cases显示文摘AIM:To determine the prevalence,histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population.METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between January 1987 and June 2007 were selected.Relevant pathologic and clinical data were extracted with supplementation from patient charts where available.Non-epithelial tumours were excluded.The total number of appendectomy specimens over the period was also ascertained.RESULTS:Forty-two primary epithelial tumours were identified out of 6 824 appendectomies yielding a prevalence rate of approximately 0.62%.Well- differentiated neuroendocrine cell tumours(carcinoids,47.6%)and benign non-endocrine cell tumours(adenomas,45.2%)were most common with nearly equal frequency.The median age was 43 years,with no sex predilection.Carcinoid tumours occurred in younger patients(mean age 32 years),with a male-to-female ratio of 1.2:1.A clinical diagnosis of acute appendicitis was the most common reason for appendectomy(57.1%)and was histologically confirmed in 75%(18 of 24)of cases.In total,16.7%of cases were diagnosed after incidental appendectomy.CONCLUSION:Appendiceal epithelial tumours arerare in our experience,and are represented principally by carcinoid tumours and adenomas.Carcinoid tumours occurred in younger patients but were slightly more common in men than women.Tumours were not suspected clinically and were diagnosed incidentally in specimens submitted for acute appendicitis supporting the need for histological evaluation in all resection specimens.Rondell Patrell Darrell Graham Nadia Patricia Williams Kamille Aisha West 2009World Journal of Gastroenterology2009,15,12:2
12Influence of catalytic systems on process of model object hydrogenation显示文摘On the basis of b-FeOOH,Fe(OA)_(3),Fe_(3)O_(4) iron and spherical catalysts NiO/SiO_(2),Fe_(2)O_(3)/SiO_(2) derived from slag waste coals of heating electrical stations,the hydrogenation of model polycyclic hydrocarbon at presence of nanodimensioned catalysts antracene was studied.On the example of conversion of anthracene,it was shown that upon release of hydrogenation of the product yield and degradation of polycyclic hydrocarbons in the hydrogenation,the mentioned catalyst systems appeared to be in the following order:nanoparticles b-FeOOH,Fe(OA)_(3) and Fe_(3)O_(4)[spherical catalysts NiO/SiO_(2),Fe_(2)O_(3)/SiO_(2)[commercial cobalt-molybdenum catalyst.The results showed that the catalysts studied are promising catalysts for the hydrogenation of polycyclic hydrocarbons and may be used for direct coal liquefaction.Murzabek Ispolovich Baikenov Gulzhan Gausilevna Baikenova Bolat Shaimenovich Sarsembayev Alma Baimagambetova Tateeva Almas Tusipkhan Aisha Zharasovna Matayeva 2014International Journal of Coal Science & Technology2014,1,1:2
13Safety and efficacy of Hansenula-derived PEGylated-interferon alpha-2a and ribavirin combination in chronic hepatitis C Egyptian children显示文摘AIM:To investigate the safety and efficacy of a Hansenula-derived PEGylated(polyethylene glycol)interferon(IFN)-alpha-2a(Reiferon Retard)plus ribavirin customized regimen in treatment-na?ve and previously treated(non-responders and relapsers)Egyptian children with chronic hepatitis C infection.METHODS:Forty-six children with chronic hepatitis C virus(HCV)infection were selected from three tertiary pediatric hepatology centers.Clinical and laboratory evaluations were undertaken.Quantitative polymerase chain reaction(PCR)for HCV-RNA was performed before starting treatment,and again at 4,12,24,48,72wk during treatment and 6 mo after treatment cessation.All patients were assigned to receive a weekly subcutaneous injection of PEG-IFN-alpha-2a plus daily oral ribavirin for 12 wk.Thirty-four patients were treatment-na?ve and 12 had a previous treatment trial.Patients were then divided according to PCR results into two groups.GroupⅠincluded patients who continued treatment on a weekly basis(7-d schedule),while groupⅡincluded patients who continued treatment on a 5-d schedule.Patients from either group who were PCR-negative at week 48,but had at least one PCRpositive test during therapy,were assigned to have an extended treatment course up to 72 wk.The occurrence of adverse effects was assessed during treatment and follow up.The study was registered at www.ClinicalTrials.gov(NCT02027493).RESULTS:Only 11 out of 46(23.9%)patients showed a sustained virological response(SVR),two patients were responders at the end of treatment;however,they were lost to follow up at 6 mo post treatment.Breakthrough was seen in 18(39.1%)patients,one patient(2.17%)showed relapse and 14(30.4%)were non-responders.Male gender,short duration of infection,low viral load,mild activity,and mild fibrosis were the factors related to a better response.On the other hand,patients with high viral load and absence of fibrosis failed to respond to treatment.Before treatment,liver transaminases were elevated.After commencing treatment,they were normalized in all patients at week 4 and were maintained normal in responders till the end of treatment,while they increased again significantly in non-responders(P=0.007 and 0.003 at week 24 and 72 respectively).The 5-d schedule did not affect the response rate(1/17 had SVR).Treatment duration(whether 48 wk or extended course to 72 wk)gave similar response rates(9/36 vs 2/8 respectively;P=0.49).Type of previous treatment(short acting IFN vs PEG-IFN)did not affect the response to retreatment.On the other hand,SVR was significantly higher in previous relapsers than in previous non-responders(P=0.039).Only mild reversible adverse effects were observed and children tolerated the treatment well.CONCLUSION:Reiferon Retard plus ribavirin combined therapy was safe.Our customized regimen did not influence SVR rates.Further trials on larger numbers of patients are warranted.Suzan El Naghi Tawhida Y Abdel-Ghaffar Hanaa El-Karaksy Elham F Abdel-Aty Mona S El-Raziky Aleef A Allam Heba Helmy Hanaa A El-Araby Behairy E Behairy Mohamed A El-Guindi Hatem El-Sebaie Aisha Y Abdel-Ghaffar Nermin A Ehsan Ahmed M El-Hennawy Mostafa M Sira 2014World Journal of Gastroenterology2014,20,16:2
14Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia显示文摘Kristi A Sacco Angelo Termine Aisha Seyal 2005Arch Gen Psychiatry2005,62,6:1
15The flipped classroom for medical students显示文摘Helen Morgan Karen McLean Chris Chapman James Fitzgerald Aisha Yousuf Maya Hammoud 2015Clin Teach2015,,3:1
16Comparison Using Gas Chromatography -- Mass Spectrometry and Target Ion Response显示文摘Aisha of Gasolines T Barnes Julia A Dolan 2004Journal of Forensic Sciences2004,49,5:1
17Leukemia inhhibitory factor:Role in human mesenchymal stem cells mediated immunosuptor:Role in human mesenchymal stem cells mediated immunosuppression显示文摘Aisha N Christelle M Sandrine B 2008Cell Immuol2008,253,1:1
18Cytotoxic activity of Catharanthus roseus (Apocynaceae) crude extracts and pure compounds against human colorectal carcinoma cell line 显示文摘Siddiqui M J Ismail Z Aisha A F A 2010lntern J Pharmacol2010,6,1:1
19Kashin-Beck disease andsayiwak disease in China: prevalence and a comparison of theclinical manifestations, familial aggregation, and heritability显示文摘Lu AL Guo X Aisha MM 2011Bone2011,48,2:1
20Neurophysiological aspects of primary insomnia:Implications for its treatment显示文摘Aisha C Edwin V Raymond C 2006Sleep Med Revi2006,,4:1
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