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| 1 | A handy review of carpal tunnel syndrome:From anatomy to diagnosis and treatment显示文摘Carpal tunnel syndrome(CTS) is the most commonly diagnosed disabling condition of the upper extremities. It is the most commonly known and prevalent type of peripheral entrapment neuropathy that accounts for about 90% of all entrapment neuropathies. This review aims to provide an outline of CTS by considering anat-omy, pathophysiology, clinical manifestation, diagnostic modalities and management of this common condition, with an emphasis on the diagnostic imaging evaluation. | Mohammad Ghasemi-rad Emad Nosair Andrea Vegh Afshin Mohammadi Adam Akkad Emal Lesha Mohammad Hossein Mohammadi Doaa Sayed Ali Davarian Tooraj Maleki-Miyoab Anwarul Hasan | 2014 | World Journal of Radiology2014，6，6： | 24 |
| 2 | Low gradient ascites: A seven-year course review显示文摘AIM: To study the patients with low gradient ascites in hospitals of Guilan Province (northern Iran).METHODS: Patients admitted in hospitals of Guilan Province with low gradient ascites from 1993 to 2000 were enrolled in the study. Serum and ascitic fluid albumin levels were determined by biochemical reactions. The serum-ascitic albumin gradient (SAAG) less than 1.1 g/dL was considered low. Statistical analysis was performed with SPSS 9.0software and P<0.05 was considered statistically significant.RESULTS: Of the 148 patients enrolled in the study, 72(48.6%) were males and 76 (51.4%) were females with a mean age of 59.03±13.54 years. Tuberculous peritonitis was the most frequent cause of low gradient ascites in 68 (45.9%). Other most frequent causes were cancer in 62 (41.9%), nephrotic syndrome in 9 (6%), pancreatitis in 6 (4%). Peritoneal cancer was found in 22 (35%),ovarian and gastric cancers were found in 14 (22.5%)and 12 (19.3%), respectively. All of which were the causes of ascites. The mean SAAG was 0.68±0.19 g/dL. The mean serum and ascitic fluid albumin concentrations were higher in tuberculous patients (P<0.006), but lactate dehydrogenase (LDH) level was higher in cancer patients (P<0.0001). In peritoneal tuberculosis, mean ascitic glucose concentration was significantly lower than other patients (P<0.0001).CONCLUSION: Tuberculosis should be considered in all patients with low gradient ascites especially in developing countries (like Iran), as the first cause of ascites. In the approach to patients with low gradient ascites, ascitic fluid glucose, and LDH level are useful indicators for decision making. | Fariborz Mansour-Ghanaei Afshin Shafaghi Amir-Hossein Bagherzadeh Mohammad-Sadegh Fallah | 2005 | World Journal of Gastroenterology2005，11，15： | 15 |
| 3 | 口腔护理对危重症患者口腔健康状况和呼吸机相关性肺炎预防的影响显示文摘目的:本研究的目的是明确口腔护理措施对重症监护室患者口腔健康状况和呼吸机相关性肺炎发生率的影响。方法:本临床实验纳入2015-2016年间的100名患者,随机分为对照组(接受护士的口腔护理)和干预组(接受研究人员的系统口腔护理)。根据干预组患者的口腔健康状况,按照Beck口腔护理频次评价表(BOAS)确定需要接受口腔护理的频次。每次护理均包括调整气管内套管压力、用牙膏刷牙、使用抗菌药和嘴唇保湿。口腔检查采用BOAS和口腔黏膜菌斑量表评分,肺炎监测采用临床肺部感染评分。结果:第1~5天,两组患者的BOAS评分有统计学差异(P<0.001);第3~5天,两组患者的口腔黏膜菌斑评分有统计学差异(P<0.001);第3天和第5天,对照组肺炎发生率分别为10%(5例)和14%(7例),干预组肺炎发生率分别为4%(2例)和10%(5例),Fisher检验无统计学差异(P=0.538),但与对照组相比,干预组肺炎的发生率降低。结论:与传统的口腔护理措施比较,系统口腔护理虽然没有显著降低危重症患者呼吸机相关性肺炎的发生率,但显著改善了其口腔健康状况和口腔黏膜菌斑评分。 | Abdullah Haghighi Vida Shafipour Masoumeh Bagheri-Nesami Afshin Gholipour Baradari Jamshid Yazdani Charati | 2017 | 中国护理管理2017，17，3： | 14 |
| 4 | Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response显示文摘AIM: To investigate the co-incidence of apoptosis, autophagy, and unfolded protein response(UPR) in hepatitis B(HBV) and C(HCV) infected hepatocytes.METHODS: We performed immunofluorescence confocal microscopy on 10 liver biopsies from HBV and HCV patients and tissue microarrays of HBV positive liver samples. We used specific antibodies for LC3β, cleaved caspase-3, BIP(GRP78), and XBP1 to detect autophagy, apoptosis and UPR, respectively. AntiHCV NS3 and anti-HBs antibodies were also used to confirm infection. We performed triple blind counting of events to determine the co-incidence of autophagy(LC3β punctuate), apoptosis(cleaved caspase-3), and unfolded protein response(GRP78) with HBV and HCV infection in hepatocytes. All statistical analyses were performed using SPSS software for Windows(Version 16 SPSS Inc, Chicago, IL, United States). P-values < 0.05 were considered statistically significant. Statistical analyses were performed with Mann-Whitney test to compare incidence rates for autophagy, apoptosis, and UPR in HBV- and HCV-infected cells and adjacent noninfected cells.RESULTS: Our results showed that infection of hepatocytes with either HBV and HCV induces significant increase(P < 0.001) in apoptosis(cleavage of caspase-3), autophagy(LC3β punctate), and UPR(increase in GRP78 expression) in the HCV- and HBVinfected cells, as compared to non-infected cells of the same biopsy sections. Our tissue microarray immunohistochemical expression analysis of LC3β in HBV^(Neg) and HBV^(Pos) revealed that majority of HBVinfected hepatocytes display strong positive stainingfor LC3β. Interestingly, although XBP splicing in HBVinfected cells was significantly higher(P < 0.05), our analyses show a slight increase of XBP splicing was in HCV-infected cells(P > 0.05). Furthermore, our evaluation of patients with HBV and HCV infection based on stage and grade of the liver diseases revealed no correlation between these pathological findings and induction of apoptosis, autophagy, and UPR.CONCLUSION: The results of this study indicate that HCV and HBV infection activates apoptosis, autophagy and UPR, but slightly differently by each virus. Further studies are warranted to elucidate the interconnections between these pathways in relation to pathology of HCV and HBV in the liver tissue. | Behzad Yeganeh Adel Rezaei Moghadam Javad Alizadeh Emilia Wiechec Seyed Moayed Alavian Mohammad Hashemi Bita Geramizadeh Afshin Samali Kamran Bagheri Lankarani Martin Post Payam Peymani Kevin M Coombs Saeid Ghavami | 2015 | World Journal of Gastroenterology2015，21，47： | 13 |
| 5 | Ankylosing spondylitis: A state of the art factual backbone显示文摘Ankylosing spondylitis(AS) is a chronic inflammatory disease that affects 1% of the general population. As one of the most severe types of spondyloarthropathy, AS affects the spinal vertebrae and sacroiliac joints, causing debilitating pain and loss of mobility. The goal of this review is to provide an overview of AS, from the pathophysiological changes that occur as the disease progresses, to genetic factors that are involved with its onset. Considering the high prevalence in the population, and the debilitating life changes that occur as a result of the disease, a strong emphasis is placed on the diagnostic imaging methods that are used to detect this condition, as well as several treatment methods that could improve the health of individuals diagnosed with AS. | Mohammad Ghasemi-rad Hosam Attaya Emal Lesha Andrea Vegh Tooraj Maleki-Miandoab Emad Nosair Nariman Sepehrvand Ali Davarian Hamid Rajebi Abdolghader Pakniat Seyed Amirhossein Fazeli Afshin Mohammadi | 2015 | World Journal of Radiology2015，7，9： | 13 |
| 6 | GIS-based spatial analysis of urban traffic accidents: Case study in Mashhad, Iran显示文摘There is a growing concern in traffic accident rate in recent years. Using Mashhad city(Iran second populous city) traffic accident records as case study, this paper applied the combination of geo-information technology and spatial-statistical analysis to bring out the influence of spatial factors in their formation. The aim of the study is to examine 4 clustering analyses to have a better understanding of traffic accidents patterns in complex urban network. In order to deploy the clustering technique in urban roads, 9331 point features for inner city traffic accidents during 12 months have been registered according to their x and y location in geographic information system(GIS). The mentioned areas were analyzed by kernel density estimation(KDE) using ARCMAP and two other analyses using SANET 4th edition software so that the results of network analysis can be compared with traditional KDE method. In addition, this research introduces five classifications for determining the eventfulness of the under study area based on standard deviation and to make priority in creating security in the area.The nearest neighbor and K-function output analysis consist of four curves and regarding the fact that for all fatal, injury and property damage only crashes, the observed value curve is above the 5% confidence interval. Accidents in the study region are more clustered than expected by random chance. The importance of this study is to use GIS as a management system for accident analysis by combination of spatial-statistical methods. | Gholam Ali Shafabakhsh Afshin Famili Mohammad Sadegh Bahadori | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，3： | 8 |
| 7 | Reserve estimation of an open pit mine under price uncertainty by real option approach显示文摘Reserve estimation is a key to find the correct NPV in a mining project. The most important factor in reserve estimation is the metal price. Metal price fluctuations in recent years were exaggerated, and imposed a high degree of uncertainty to the reserve estimation, and in consequence to the whole mine planning procedure. Real option approach is an efficient method of decision making in the uncertain conditions. This approach has been used for evaluation of defined natural resources projects until now. This study considering the metal price uncertainty used real option approach to prepare a methodology for reserve estimation in open pit mines. This study was done on a copper cylindrical deposit, but the achieved methodology can be adjusted for all kinds of deposits. This methodology was comprehensively described through the examples in such a manner that can be used by the mine planners. | AKBARI Afshin Dehkharghani OSANLOO Morteza SHIRAZI Mohsen Akbarpour | 2009 | Mining Science and Technology2009，19，6： | 8 |
| 8 | New Optimization Method, the Algorithms of Changes, for Heat Exchanger Design显示文摘Heat exchangers are widely used in the process engineering such as the chemical industries,the petroleum industries,and the HVAC applications etc.An optimally designed heat exchanger cannot only help the optimization of the equipment size but also the reduction of the power consumption.In this paper,a new optimization approach called algorithms of changes (AOC) is proposed for design and optimization of the shell-tube heat exchanger.This new optimization technique is developed based on the concept of the book of changes (I Ching) which is one of the oldest Chinese classic texts.In AOC,the hexagram operations in I Ching are generalized to binary string case and an iterative process,which imitates the I Ching inference,is defined.Before applying the AOC to the heat exchanger design problem,the new optimization method is examined by the benchmark optimization problems such as the global optimization test functions and the travelling salesman problem (TSP).Based on the TSP results,the AOC is shown to be superior to the genetic algorithms (GA).The AOC is then used in the optimal design of heat exchanger.The shell inside diameter,tube outside diameter,and baffles spacing are treated as the design (or optimized) variables.The cost of the heat exchanger is arranged as the objective function.For the heat exchanger design problem,the results show that the AOC is comparable to the GA method.Both methods can find the optimal solution in a short period of time. | TAM Houkuan TAM Lapmou TAM Sikchung CHIO Chouhei GHAJAR Afshin J | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 6 |
| 9 | 插电式混合电动汽车动力系结构的非线性约束优化(英文)显示文摘为了优化插电式混合电动汽车(PHEV)动力系(例如发动机功率、电动机功率、相关经济效率)构件尺寸,使用了'粒子群优化'(PSO)方法。对于非线性约束优化问题,PSO方法比常规优化方法更有效、经济。用动力系反洗工具箱(PSAT)方法,构建了新的带有优化配置的PHEV动力系的模型系。仿真计算结果表明:运用PSO优化构件的汽车,具有同等的驾驶性能,在燃料消耗上达30%的改进。 | Emrah T.YILDIZ Quazi FAROOQI Sohel ANWAR Yaobin CHEN Afshin IZADIAN | 2012 | 汽车安全与节能学报2012，3，1： | 5 |
| 10 | GIS-based method for detecting high-crash-risk road segments using network kernel density estimation显示文摘Identifying high-crash-risk road segments provides safety specialists with an insight to better understanding of crash patterns and enhancing road safety management.The common hotspot identification methods are not robust enough to visualize the underlying shape of crash patterns since they neglect the spatial properties of crash data.Spatial traffic accidents have the tendency to be dependent,a phenomenon known as spatial autocorrelation.Values over distance are more or less similar than expected for randomly associated observations.Modeling the spatial variations can properly be explained in terms of first-and second-order properties.The first-order properties,describe the way of varying the expected value of point pattern in space which can be due to changes in the substantial properties of the local environment,while second-order effects describe the interactive effects of events explaining on how the events are interacted.Considering the discrete nature of crash data and the limited access to exact locations where crashes occur,it is likely that a continuous surface drawn from discrete points will better reflect crash density,present a more realistic picture of crash distribution.Network kernel density estimation(NKDE)is a nonparametric approach for events distributed over one-dimensional space which facilitates estimating the density at any location in the study region not just at the location where the event occurs.NKDE for road safety applications enables the extraction and visualization of crash density along roadways The application of suggested method was illustrated for Arak-Khomein rural road in Markazi province,Iran and the stability of hazardous segments by examining the resulted network estimated density during the three years of study(2006–2008)was investigated.The result of this paper helps the traffic engineers and safety specialists to determine the segments which demand more safety attentions from both transportation authorities and drivers and request assigning the resources such as budget and time. | Afshin Shariat MOHAYMANY Matin SHAHRI Babak MIRBAGHERI | 2013 | Geo-Spatial Information Science2013，16，2： | 5 |
| 11 | Combined heat and power economic dispatch problem using firefly algorithm显示文摘 | Afshin YAZDANI T. JAYABARATHI V. RAMESH T. RAGHUNATHAN | 2013 | Frontiers in Energy2013，7，2： | 5 |
| 12 | Effects of Matricaria chamomilla Extract on Growth and Maturation of Isolated Mouse Ovarian Follicles in a Three-dimensional Culture System显示文摘 | Hamed Shoorei Arash Khaki Nava Ainehchi Mohammad Mehdi Hassanzadeh Taheri Moloud Tahmasebi Giti Seyedghiasi Ziba Ghoreishi Majid Shokoohi Amir Afshin Khaki Sayed Haidar Abbas Raza | 2018 | Chinese Medical Journal2018，，2： | 4 |
| 13 | Combined heat and power economic dispatch problem using the invasive weed optimization algorithm显示文摘 | T. JAYABARATHI Afshin YAZDANI V. RAMESI T. RAGHUNATHAN | 2014 | Frontiers in Energy2014，8，1： | 4 |
| 14 | A simulation study of water injection and gas injectivity scenarios in a fractured carbonate reservoir:A comparative study显示文摘Regarding the enormous demands of numerous industries to fossil fuels,it is essential to select the proper enhanced oil recovery approaches for vertical and horizontal wells to supply the demands with the optimum expenditure.Water and gas injectivity as the secondary enhanced oil recovery techniques would be preferentially considered regarding their low costs of performances rather than chemical recovery and thermal techniques.Injected gas tends to push oil through pores or cracks in the matrix block and lead them to the production well.Therefore,injection of gas may significantly increase the recovery factor in these reservoirs.In this research,different injection scenarios in a fractured carbonate reservoir in the west of Iran are being simulated by the PVT modules of Eclipse software.The purpose of this research is to analyze the possibility of gradually increasing the extent of recovery by injecting carbon dioxide,methane,and water,and different injectivity patterns are considered in this research.The selection of injectivity patterns is severely based on the highest recycling rate of gas injection on different injection scenarios,and the injectivity scenarios were being compared with the natural depletion scenario.Consequently,Co2 injection(about 60%)had the highest oil recovery factor and CH4 and TB(about 54%and 53%)injectivity scenarios had the second and third highest rate of the oil recovery factor. | Afshin Davarpanah Behnam Mirshekari A.Armin Razmjoo | 2019 | Petroleum Research2019，4，3： | 4 |
| 15 | Efficacy of saccharomyces boulardii with antibiotics in acute amoebiasis显示文摘AIM: To compare the efficacy of antibiotics therapy alone with antibiotics and saccharomyces boulardii in treatment of acute amebiasis.METHODS: In a double blind, random clinical trial on patients with acute intestinal amoebiasis, 57 adult patients with acute amoebiasis, diagnosed with clinical manifestations (acute mucous bloody diarrhea) and amebic trophozoites engulfing RBCs found in stool were enrolled in the study.Regimen 1 induded metronidazole (750 mg Tid) and iodoquinol (630 mg Tid) for 10 days. Regimen 2 contained capsules of lyophilized saccharomyces boulardii (250 mg Tid) orally in addition to regimen 1. Patients were re-examined at two and four weeks after the treatment, and stool examination was performed at the end of week 4. Student′s t-test, χ2and McNemar′s tests were used for statistical analysis.RESULTS: Three patients refused to participate. The other 54 patients were randomized to receive either regimen 1 or regimen 2 (Groups 1 and 2 respectively, each with 27patients). The two groups were similar regarding their age,sex and clinical manifestations. In Group 1, diarrhea lasted 48.0±18.5 hours and in Group 2,12.0±3.7 hours (P<0.0001).In Group 1, the durations of fever and abdominal pain were 24.0±8.8 and 24.0±7.3 hours and in Group 2 they were 12.0±5.3 and 12.0±3.2 hours, respectively (P<0.001).Duration of headache was similar in both groups. At week 4, amebic cysts were detected in 5 cases (18.5 %) of Group 1 but in none of the Group 2 (P<0.02).CONCLUSION: Adding saccharomyces boulardii to antibiotics in the treatment of acute amebiasis seems to decrease the duration of clinical symptoms and cyst passage. | Fariborz Mansour-Ghanaei Najaf Dehbashi Kamyar Yazdanparast Afshin Shafaghi | 2003 | World Journal of Gastroenterology2003，9，8： | 3 |
| 16 | Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells显示文摘Background: The objective of this study was to study how changing the ratio of Lys to Thr, Lys to His, and Lys to Val affects the expression of lipogenic genes and micro RNA(mi RNA) in bovine mammary epithelial cells.Results: Triplicate cultures with the respective 'optimal' amino acid(AA) ratio(OPAA = Lys:Met 2.9:1; Thr:Phe 1.05:1;Lys:Thr 1.8:1; Lys:His 2.38:1; Lys:Val 1.23:1) plus rapamycin(OPAARMC; positive control), OPAA, Lys:Thr 2.1:1(LT2.1),Lys:Thr 1.3:1(LT1.3), Lys:His 3.05:1(LH3.0), or Lys:Val 1.62:1(LV1.6) were incubated in lactogenic medium for 12 h.The expression of 15 lipogenic genes and 7 mi RNA were evaluated. Responses to LT2.1, LT1.3, LH3.0, and LV1.6relative to the control(OPAARMC) included up-regulated expression of ACSS2, FABP3, ACACA, FASN, SCD, LPIN1,INSIG1, SREBF1, PPARD, and NR1H3(commonly known as LXR-α). Furthermore, LV1.6 up-regulated expression of ACSL1, DGAT1, and RXRA and down-regulated PPARG expression. Although no effect of OPAA on expression of PPARG was observed, compared with the control, OPAA up-regulated expression of the PPAR targets ACSS2, FABP3,ACACA, FASN, SCD, LPIN1, INSIG1, and SREBF1. Compared with the control, the expression of the anti-lipogenic MIR27 AB was down-regulated by OPAA, LT2.1, LT1.3 and LH3.0. In contrast, compared with the control, the expression of the pro-lipogenic MIR21 was up-regulated by LT2.1, LT1.3, LH3.0, and LV1.6.Conclusions: The observed up-regulation of lipogenic gene networks and the changes in expression of key mi RNA involved in the control of lipogenic balance are indicative of a potentially important role of EAA ratios and m TOR signaling in the regulation of milk fat synthesis. | Shanshan Li Afshin Hosseini Marina Danes Carolina Jacometo Jianxin Liu Juan J.Loor | 2016 | Journal of Animal Science and Biotechnology2016，7，4： | 3 |
| 17 | Removal of methyl orange from aqueous solution by Azolla filicoloides:Synthesis of Fe_3O_4 nano-particles and its surface modification by the extracted pectin of Azolla显示文摘有从 Azolla filicoloides (FN-EP ) 的房间墙的提取果胶的修改 Fe3O4 nano 粒子能独自从 Azolla (EPA ) 作为水溶性的偶氮的染料把甲基橘子从比 Azolla 和提取果胶好的浪费水移开。它能由于与 nano 粒子在有约束力的果胶以后挤满举起的主要的功能的组的更多。热力学的研究显示出那个吸附平衡常数(KL ) ,最大的吸附能力(Qmax ) 与减少的温度被增加(发热) 。由在一个批反应堆的 FN-EP 的染料的最大的举起能力(Qmax ) 是在 5, 25 和 50 潣摮湥慳楴湯漠 ? 的 0.533, 0.498 和 0.446 mmol/g ? 桰湥汹湥摥慩業敮 ? 楷桴ㄠ水搭捩牡潢祮 ? 潣灭畯摮 ? 湩琠敨瀠敲敳据 ? 景挠瑩楲? 捡摩愠晦牯敤 ? 桴 ? 潣牲獥潰摮湩 ? 畱湩硯污湩 ? 敤楲慶楴敶 ? 湩栠杩敨 ? 楹汥獤愠 ? 潲浯琠浥数慲畴敲椠 ? 瑥慨潮 ? 愠摮洠獯 ? 景琠敨爠慥瑣潩獮眠牥 ? 潣灭敬整 ? 湩吗? | Roohan Rakhshaee Masoud Giahi Afshin Pourahmad | 2011 | Chinese Chemical Letters2011，22，4： | 3 |
| 18 | Anti-oxidative role of quercetin derived from Allium cepa on aldehyde oxidase(OX-LDL)and hepatocytes apoptosis in streptozotocininduced diabetic rat显示文摘Objective:To study the role of Quercetin in streptozotocin-induced diabetes in rals.Methods:Wistar male rat(n=40) were allocated into three groups,control group(n=10) and Quercetin(QR) group received 15 mg/kg(IP) QR.(n=10),and diabetic group that received 55 mg/kg(IP)streptozotocin(STZ)(n=20) which was subdivided to two groups of 10;STZ group and treatment group.Treatment group received 55mg/kg(IP) STZ plus 15 nig/kg QR,daily lor 4 weeks,respectively:however,the control group just received an equal volume of distilled water dailv(IP).Diabetes was induced by a single(IP) injection of streptozotocin(55 mg/kg).Animal-were kept in standard condition.Twenty-eight days after inducing diabetic,5 mL blood were collected for TAC,MPA and Ox-LDL levels and liver tissues of rat in whole groups were removed then prepared for apoptosis analysis by Tunel method.Results:Apoptotic cells significantly decreased in group that has received 15 mg/kg(IP) Quercetin(P<0.05) in comparison to experimental groups(P<0.05).Conclusions:Since in our study 15 nig/kg(IP) Quercetin have significantly Preventive ellecl on liver cells damages by reducing number of apoptotic cells in Liver,so it seems that using it can be effective for treatment in diabetic rat. | Mina Bakhshaeshi Arash Khaki Fatemeh Fathiazad Amir Afshin Khaki Elham Ghadamkheir | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，7： | 2 |
| 19 | Phase II trial of Sorafenib in conjunction with chemotherapy and as maintenance therapy in extensive-stage small cell lung cancer显示文摘 | Neelesh Sharma Nathan Pennell Myles Nickolich Balazs Halmos Patrick Ma Tarek Mekhail Pingfu Fu Afshin Dowlati | 2014 | Investigational New Drugs2014，，2： | 2 |
| 20 | Associations of a TLR4 single-nucleotide polymorphism with H. pylori associated gastric diseases in iranian patients显示文摘 | Nader Bagheri Fatemeh Azadegan-Dehkordi Hosein Sanei Afshin Taghikhani Ghorbanali Rahimian Loghman Salimzadeh Morteza Hashemzadeh-Chaleshtori Mahmoud Rafieian-kopaei Maryam Shirzad Hedayatollah Shirzad | 2013 | Clinics and Research in Hepatology and Gastroenterology2013，，： | 2 |
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