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| 1 | Treatment and prognosis of hepatic epithelioid hemangioendothelioma based on SEER data analysis from 1973 to 2014显示文摘Background: Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular origin with an unknown etiology, a low incidence, and a variable natural course. We evaluated the management and prognosis of HEH from the Surveillance, Epidemiology and End Results (SEER) program and changes in treatment modalities of HEH over 30 years. Methods: From 1973 to 2014 in the SEER database, we selected patients diagnosed with HEH. We analyzed the clinical characteristics, patterns of management, and clinical outcomes of patients with HEH. Results: We identi ed 79 patients with HEH (median age: 54.0 years;male to female ratio: 1:2.6). The initial extent of disease was local in 22 (27.8%) patients, regional metastasis in 22 (27.8%), distant metas-tasis in 31 (39.2%) and unknown in 4 (5.1%). The median size of primary tumor was 3.85 cm (interquartile range, 2.50 7.93 cm). Among 74 patients with available management data, the most common manage-ment was no treatment (29/74, 39.2%), followed by chemotherapy only (22/74, 29.7%), liver resection-based (13/74, 17.6%), and transplantation-based therapy (6/74, 8.1%). The 5-year cancer-speci c survival rate was 57.8%. Patients who underwent surgical treatment had signi cantly higher survival than those who underwent non-surgical treatment (5-year survival;88% vs. 49%, P=0.019). Multivariate analysis revealed that surgical therapy was the only independent prognostic factor for survival (hazard ratio: 0.20, P=0.040). Conclusions: Resection or liver transplantation is worth considering for treatment of patients with HEH. | O Kyu Noh Soon Sun Kim Min Jae Yang Sun Gyo Lim Jae Chul Hwang Hyo Jung Cho Jae Youn Cheong Sung Won Cho | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 7 |
| 2 | Enhancement by glutathione depletion of ethanol - induced acute hepatotoxicity in vitro and in vivo 显示文摘 | Strubeh O Younes M Pentz R | 1987 | Toxicology1987，45，2： | 1 |
| 3 | Status of antioxidant enzyme: glutathione peroxidase and total polyphenol level in plasma of Tunisian patients suffering from colorectal and gastric cancer: interaction with clinical outcome显示文摘 | Baroudi O Younes S B Mezlini A | 2013 | Med Oncol2013，30，4： | 1 |
| 4 | NOX4 as the major catalytic component of an endothelial NAD(P)H oxidase显示文摘 | Tetsuro A Takanari K Hiroaki O Teruaki I Youn HH Junichi T | 2004 | Circulation2004，109，： | 1 |
| 5 | Metrics and meth- ods for benchmarking of RF transmitter behavioral models with application to the development of a hybrid memory polynomial model显示文摘 | Hammi O Younes M Ghannouchi F M | 2010 | Broadcasting IEEE Transactions on2010，56，3： | 1 |
| 6 | Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck 显示文摘 | Younes M N Yigitbasi O G Yazici Y D et at | 2007 | Arch Otolaryngol Head Neck Surg2007，133，1： | 1 |
| 7 | Isotope studies of photocatalysis Ti O2-mediated degradation of Dimethyl Phenylphosphonate显示文摘 | Youn C O Yun B William S J | 2003 | Journal of Photochemistry and Photobiology A:Chemistry2003，161，1： | 1 |
| 8 | Enhancement by glutathione deple- tion of ethanol induced acute hepatotoxicity in vitro and in vivo显示文摘 | Strubelt O Younes M Pentz R | 1987 | Toxicology1987，45，2： | 1 |
| 9 | Enhancement by glutathione dep letion of ethanol2induced acute hepatotoxicity in vitro and in vivo 显示文摘 | Strubelt O Younes M Pentz R | 1982 | Toxicology1982，45，2： | 1 |
| 10 | Isola- tion, serologic and molecular characterization of the first G3 caprine rotavirus 显示文摘 | Lee J B Youn S J Nakagomi T Park S Y Kim T J Song C S Jang H K Kim B S Nakagomi O | 2003 | Arch Virol2003，148，4： | 1 |
| 11 | The anomalous codeposition of tungsten in the presence of nickel显示文摘 | YOUNES M O ZHU L GILEADI E | 2003 | Electrochimca Acta2003，48，18： | 1 |
| 12 | The anomalous codeposition of tungsten in the presence of nickel显示文摘 | YOUNES M O ZHU L GILEADI E | 2003 | Electroehimica Acta2003，48，18： | 1 |
| 13 | Effects of the integrinlinked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck显示文摘 | Younes M N Yigitbasi O G Yazici Y D | 2007 | Arch Otolaryngol Head Neck Surg2007，133，1： | 1 |
| 14 | In vitro assessment of platelet storage lesion in leucoreduced random donor platelet concentrates显示文摘 | Ahmed AS Leheta O Younes S | 2010 | Blood Transfus2010，8，1： | 1 |
| 15 | Metrics and methods for benchmarking of RF transmitter behavioral models with application to the development of a hybrid memory polynomial Model 显示文摘 | Hammi O Younes M and Ghannouchi F M | 2010 | IEEE Transactions on Broadcasting2010，56，3： | 1 |
| 16 | Lymphocytes subsets in osteoarthritis versus rheumatoid arthritis显示文摘 | Leheita O Abed Elrazek NY Younes S | | 0，，2： | 1 |
| 17 | Enhancement by glutathione depletion of ethanol-induced acute hepatotoxicity in vitro and in vivo显示文摘 | Strubelt O Younes M Pentz R | 1987 | Toxicology1987，45，2： | 1 |
| 18 | An accurate complexity-reduced 'PLUME' model for behavioral modeling and digital predistortion of RF power amplifiers 显示文摘 | Younes M and Hammi O | 2011 | IEEE Transactions on Industrial Electronics2011，58，4： | 1 |
| 19 | Electroplating of amorphous thin films of tungsten/nickel alloys显示文摘 | Younes O Zhu L Rosenberg Y | 2001 | Langmuir2001，17，12： | 1 |
| 20 | Isotope studies of photocatalysis TiO2-mediated degradation of dimethyl phenylphosphonate显示文摘 | Youn C O Yun B William S J | 2003 | J Photochem and Photobio A: Chem2003，161，： | 1 |
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