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| 1 | Evaluation of modified hemodilution combined therapy in the treatment of acute ischemic stroke in the elderly显示文摘BACKGROUND: Thrombolysis therapy is not suitable for the elderly patients with acute ischemic stroke who delayed to be diagnosed for more than 3 hours, but traditional medicine is also not very ideal. OBJECTIVE: To observe the clinical therapeutic effect of modified hemodilution combined therapy applied in elderly patients with acute cerebral thrombosis and analyze the mechanism of this therapeutic method. DESIGN: 1∶1 paired grouping according to gender and controlled observation. SETTING: Department of Internal Medicine, Chengzhanyuan District, First Hospital Affiliated to Zhejiang University. PARTICIPANTS: Totally 90 elderly patients with acute ischemic stroke who received the treatment in the Cadre Ward and Mental Ward, Department of Internal Medicine, Chengzhanyuan District, First Hospital Affiliated to Zhejiang University from March 1996 to June 2004 were recruited. They all met the diagnosis criteria revised by the Fourth Academic Conference of National Cerebrovascular Diseases in 1995 and were diagnosed as acute ischemic stroke by skull CT. They were informed of therapeutic plan and detected items. According to 1∶1 paired principle in gender, 90 enrolled patients were assigned into treated group (n=45) and control group (n=45). There were 39 male and 6 female in the treatment group, and they were aged (76±6)years, ranging from 71 to 84 years, and hospitalized at the 14th to 76th hours after onset. There were 39 male and 6 female in the control group, and they were aged (76±6)years , ranging from 70 to 82 years, and hospitalized at the 16th to 72th hours after onset. METHODS: Therapeutic method: Patients of treated group received modified hemodilution combined therapy. 200 mL whole blood of patients was exchanged with 500 mL dextran-40 (including 20 mL danshen parenteral solution and 32 mg heparin) at the beginning of therapy; From the 2nd day, compound huangqi tea bag (Huangqi mainly, including danshen, honghua, chuanxiong, shishao and a little acetyl salicylic acid) was made, twice a day, 1 bag once. At the same time, the above-mentioned dextran-40 liquid of 500 mL was intravenously injected, once a day, 14 days in total; On the 6th day after therapy, the above-mentioned aseptic autoblood stored in refrigerator at 4 ℃ was transfused back into the patients following pre-treatment of high-concentration oxygenation and ultraviolet irradiation by light quantum instrument. Patients of control group were intravenously injected of 0.4 g venoruton(Traditional Chinese medicine compound parenteral solution for promoting blood circulation and removing blood stasis ) and 50 g/L glucose of 500 mL, 75 mg acetosal was taken orally, once a day, 14 days in total. ② Measurement and observation of index: Blood coagulation index, change of platelet aggregation rate and change of hemorrheology of patients in two groups were monitored before and after therapy. The level of blood lipid of patients in two groups was measured with American Beckman automatic biochemistry analyzer. Blood flow rate of middle cerebral artery of resting electrocardiogram were measured with American HP SONOS 2500 sonoscope. Neuro-dysfunction score revised in the national conference (1995) was used to evaluate the recovery of neurological function of the patients in two groups at the 3rd, 5th, 7th and 14th days after therapy. ③Therapeutic effect and adverse effect were observed at the same time. MAIN OUTCOME MEASURES: ① Changes of coagulation index, blood lipid level and hemorheology; ② Blood flow rate of middle cerebral artery and NDS of patients with acute ischemic stroke in two groups; ③Adverse effect of drug. RESULTS: Totally 90 patients were enrolled in the experiment. One patient from treated group died of hyperosmolar nonketotic diabetic coma of complicated diabetes mellitus. One patient from control group died of severe pulmonary infection. The rest 88 patients entered the stage of result analysis. ① Change of coagulation index and platelet aggregation rate: prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) of patients after therapy were significantly longer than those before therapy in the treated group and those after therapy in control group [After therapy in treated group: (18.4±1.9), (41.8±2.1), (19.7±1.7) s, Before therapy in treated group: (13.4±1.3), (35.8±1.3), (12.5±0.9) s, After therapy in control group: (16.9±1.5), (39.1±1.1), (11.9±2.1) s, P < 0.05];Concentration of fibrinogen (Fbg) after therapy was significantly lower than that before therapy in the treated group and that after therapy in control group[After therapy in treated group: (3.4±0.4) g/L; Before therapy in treated group: (4.3±0.7) g/L; After therapy in control group:(4.0±0.6) g/L; P < 0.05]. Platelet aggregation rate decreased from (37.92 ±0.85)% before therapy to (26.42±1.01)% after therapy (P < 0.01). ②Change of blood lipid level: Levels of total cholesterol (TC), triacylglycerol(TG) and low density lipoprotein cholesterol (LDL-C) of patients after therapy were significantly lower than those before therapy in treated group and those after therapy in control group [After therapy in treated group: (5.2±0.9), (1.9±0.9), (2.08±1.1) mmol/L, before therapy in treated group:(5.9±1.2), (2.8±0.9), (3.94±0.5) mmol/L, After therapy in control group: (6.0±1.1), (2.6±0.8), (3.84±0.9) mmol/L,P < 0.05]. ③ Change of hemorheology index: Hematocrit of patients of treated group was significantly lower after therapy than before therapy [Before therapy: (43.84±4.55)%;After therapy: (40.48±4.02)%;P < 0.05]. ④ Blood flow rate of middle cerebral artery of patients of treated group was significantly lower before therapy than after therapy [(90±1.2),(97±2.1) cm/s,P < 0.01]. ⑤ NDS of patients in treated group was significantly lower than of control group 14 days after therapy. The total effective rate after therapy was significantly higher in the treated group than in the control group (93%,78%, P < 0.05). ⑥There was no obvious adverse effect. CONCLUSION: Modified hemodilution combined therapy can improve hemorheology, decrease hematocrit, increase blood flow rate of middle cerebral artery, so as to improve the impaired clinical neurological function of elderly patients with acute cerebral thrombosis through anticoagulation and antiplatelet aggregative activity as well as regulating blood lipid. | Yue Chen Guangbai Xie | 2006 | Neural Regeneration Research2006，1，2： | 1 |
| 2 | Twisted Duality Symmetry and Integrability of Hybrid Superstring on AdS2 × S^2显示文摘 | XIE Xiao-Ning | 2007 | Communications in Theoretical Physics2007，48，4X： | 0 |
| 3 | Support-free interior carving for 3D printing显示文摘Recent interior carving methods for functional design necessitate a cumbersome cut-and-glue process in fabrication.Wepropose a method to generate interior voids which not only satisfy the functional purposes but are also support-free during the 3D printing process.We introduce a support-free unit structure for voxelization and derive the wall thicknesses parametrization for continuous optimization.Wealso design a discrete dithering algorithm to ensure the printability of ghost voxels.The interior voids are iteratively carved by alternating the optimization and dithering.We apply our method to optimize the static and rotational stability,and print various results to evaluate the efficacy. | Yue Xie Xiang Chen | 2017 | Visual Informatics2017，1，1： | 3 |
| 4 | Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial ifbrillation显示文摘 | Yue L Xie J Nattel S | | 0，，04： | 1 |
| 5 | Organocatalytic and direct asymmetric vinylogous Michael addition of α,α-dicyanoolefins to unsaturated aldehydes显示文摘 | XIE Jian-wu YUE Lei XUE Dong | | 0，，14： | 1 |
| 6 | RACK1 suppresses gastric tumorigenesis by stabilizing the β-catenin destruction complex显示文摘 | Yue Zhendeng Dong Xie | 2012 | Gastroenterology2012，142，： | 1 |
| 7 | Dynamic risk management in petroleum project investment based on a variable precision rough set model显示文摘 | Xie G Yue W Y Wang S Y | | 0，，： | 1 |
| 8 | Brief review:Anesthetic neuro-toxicity in the elderly,cognitive dysfunction and Alzheimer's disease显示文摘 | Bittner EA Yue Y Xie Z | | 0，，02： | 1 |
| 9 | Brief review:anesthetic neurotoxicity in the elderly,cognitive dysfunction and Alzheimer's disease显示文摘 | Bittner EA Yue Y Xie Z | | 0，，02： | 1 |
| 10 | Arsenite Removal from Simulated Groundwater by Biogenic Schwertmannite: A Column Trial显示文摘To assess the feasibility of biogenic schwertmannite to act as a sorbent for removing arsenite from groundwater, a series of biogenic schwertmannite-packed column adsorption experiments were conducted on simulated As(III)-containing groundwater. Empty bed contact time (EBCT), As(III) concentration in effluent, and the removal efficiency of As(III) through the column were investigated at pH 8.0 and temperature 25 ± 0.5℃. The results showed that the breakthrough curves were mainly dependent on EBCT values when the influent As(III) concentration was 500 μg L^(-1) and the optimum EBCT was 4.0 min. When the effluent As(III) concentration reached 10 and 50 μg L^(-1) , the breakthrough volumes for the schwertmannite adsorption column were 4 200 and 5 600 bed volume (BV), with As(III) adsorption capacity of 2.1 and 2.8 mg g^(-1) , respectively. Biogenic schwertmannite could be regenerated by 1.0 mol L^(-1) NaOH solution, and more than 80% of As(III) adsorbed on the surface of schwertmannite could be released after 3 successive regenerations. The breakthrough volume for the regenerated schwertmannite-packed column still maintained 4 000-4 200 BV when the As(III) concentration in effluent was below 10 μg L^(-1) . Compared with other sorbents for As(III) removal, the biogenic schwertmannitepacked column had a higher breakthrough volume and a much higher adsorption capacity, implying that biogenic schwertmannite was a highly efficient and potential sorbent to purify As(III)-contaminated groundwater. | XIE Yue ZHOU Li-Xiang | 2013 | Pedosphere2013，23，3： | 1 |
| 11 | Neimark-Sackerpitchfork bifurcationof the symmetric period fixed point of the Poincaremap in a three-degree-of-freedom vibro-impact sys-tem 显示文摘 | Yue Y Xie J | 2013 | International Journal of Non-Linear Me-chanics2013，48，： | 1 |
| 12 | Characterization of BoL-ryosphaeria dothidea,the causal agent of grapevine canker in China显示文摘 | Yan Jiye Xie Yue YaoShengwei | 2012 | Australasian Plant Pathology2012，41，4： | 1 |
| 13 | Lyapunov exponents and coexistence of attractors in vibro-impaet systems with symmetric two- sided rigid constraints显示文摘 | Yue Y Xie J H | 2009 | Physics Letters A2009，373，2324： | 1 |
| 14 | Study of Factors Influencing China-ASEAN Agricultural Product Trade Development in the Context of'the Belt and Road'显示文摘This paper reviewed and analyzed the current situations and influencing factors of the bilateral agricultural product trade development in China-ASEAN Free Trade Area(CAFTA),which has important practical significance for promoting the in-depth development of the free trade area and has guiding significance for precise policy implementation.Based on the status of import and export trade of agricultural products in CAFTA from 2013 to 2017,it constructed a trade gravity model.With the aid of Stata 14.0 software,it explored major factors influencing the development of bilateral agricultural trade from the total amount of agricultural products import and export and Commodity Indexes for the Standard International Trade Classification,Revision 3(SITC Rev.3)agricultural product classification data.The empirical regression results show that the GDP of ASEAN countries,the ratio of agricultural added value to GDP,and the per capita gross national income(GNI)measured based on the purchasing power parity(PPP)exchange rate have the greatest impact on agricultural product trade in CAFTA in the context of'the Belt and Road'(B&D).Based on empirical research,it came up with recommendations including adjusting the import and export structure of agricultural products,enhancing product competitive advantages,and implementing diversified markets. | Yanyu YUE Dongdi XIE | 2020 | Asian Agricultural Research2020，12，8： | 0 |
| 15 | Lax Connection of Strings in γ-Deformed Backgrounds显示文摘在我们考虑在 γ-deformed 广告3× S 3宣传的古典绳的这篇论文,背景在广告3部门上由 TsT 转变产生了,它被描述为这个组歧管 SL ( 2 , R ),然后,我们证明有扭曲的边界条件的绳的 U ( 1 )水流等于在 γ-deformed 背景的那些。用 TsT 转变,我们能在 γ-deformed 背景导出本地宽松的连接和 monodromy 矩阵与光谱参数,它保证绳理论的古典 integrability。 | XIE Xiao-Ning YUE Rui-Hong | 2008 | Communications in Theoretical Physics2008，49，5： | 0 |
| 16 | Projected relationship between ENSO and following-summer rainfall over the middle reaches of the Yangtze River valley based on CMIP6 simulations显示文摘厄尔尼诺—南方涛动(ENSO)对长江中游夏季降水(YRSR)的年际变化影响较大.基于CMIP6模式数据,本文预估了未来ENSO与长江中游夏季降水关系的变化.与1979~2014年相似,SSP5-8.5高排放情景下ENSO-YRSR的关系仍表现为前冬发生厄尔尼诺(拉尼娜)后,长江中游夏季降水为正异常(负异常).同时,仍然受三个物理过程影响:前冬ENSO影响次年夏季印度洋海温(ENSO-TIO SST),印度洋海温异常进而影响菲律宾对流(TIO SST-PSC),菲律宾对流对长江中游夏季降水产生影响(PSC-YRSR).例如,(1)5个CMIP6好模式的中位数和20个EC-Earth3好子集的中位数均预估ENSO-YRSR在2015~2100年大部分时段保持显著正相关关系,因为上述三个物理过程的相关关系在未来也显著.(2)30个CMIP6模式的中位数和56个EC-Earth3子集的中位数预估ENSO-YRSR关系略有增强;主要是因为上述三个物理过程在未来变强.(3)5个CMIP6好模式的中位数预估ENSO-YRSR关系仍强于30个CMIP6模式的中位数结果,主要是因为前者预估的TIO SST-PSC和PSC-YRSR关系更强.未来将关注ENSO-YRSR预估的不确定性来源. | Yue Sui Guoping Xie | 2023 | Atmospheric and Oceanic Science Letters2023，16，6： | 0 |
| 17 | Preparation of Zn-doped TiO_2 nanotubes electrode and its application in pentachlorophenol photoelectrocatalytic degradation显示文摘Zn-doped titanium oxide (TiO2) nanotubes electrode was prepared on a titanium plate by direct anodic oxidation and immersing method in sequence. Field emission scanning electron microscopy (FESEM) showed that the Zn-doped TiO2 nanotubes were well aligned and organized into high density uniform arrays with diameter ranging from 50 to 90 nm. The length and the thickness were about 200 and 15 nm respectively. TiO2 anatase phase was identified by X-ray diffraction (XRD). X-ray photoelectronspec-troscopy (XPS) indicated that Zn ions were mainly located on the surface of TiO2 nanotubes in form of ZnO clusters. Compared with TiO2 nanotubes electrode,about 20 nm red shift in the spectrum of UV-vis absorption was observed. The degradation of pentachlorophenol (PCP) in aqueous solution under the same condition (initial concentration of PCP: 20 mg/L; concentration of Na2SO4: 0.01 mol/L and pH: 7.03) was carried out using Zn-doped TiO2 nanotubes electrode and TiO2 nanotubes electrode. The degradation rates of PCP using Zn-doped TiO2 nanotubes electrode were found to be twice and 5.8 times as high as that using TiO2 nanotubes electrode by UV radiation (400 μw/cm2) and visible light radiation (4500 μw/cm2),respectively. 73.5% of PCP was removed using Zn-doped TiO2 nanotubes electrode against 48.5% removed using TiO2 nanotubes electrode in 120 min under UV radiation. While under visible light radiation,the degradation efficiency of PCP was 18.4% using Zn-doped TiO2 nano-tubes electrode against 3.2% using TiO2 nanotubes electrode in 120 min. The optimum concentration of Zn doping was found to be 0.909%. The PCP degradation efficiencies of the 10 repeated experiments by Zn-doped TiO2 nanotubes electrode were rather stable with the deviation within 3.0%. | ZHAO HuiMin CHEN Yue QUAN Xie RUAN XiuLi | 2007 | Chinese Science Bulletin2007，52，11： | 14 |
| 18 | Microstructure of Cu-based Amorphous Composite Coatings on AZ91D Magnesium Alloy by Laser Cladding显示文摘To improve the sliding wear resistance of AZ91D magnesium alloy,Cu-based amorphous composite coatings made of Cu47Ti34Zr11Ni8 and Cu47Ti34Zr11Ni8+20 wt pct SiC powders were fabricated on AZ91D magnesium alloy by laser cladding,respectively.SEM(scanning electron microscopy),EDS(energy dispersive X-ray spectroscopy),XRD(X-ray diffraction) and TEM(transmission electron microscopy) techniques were employed to study the phases of the coatings.The results show that the coatings mainly consist of amorphous phase and different intermetallic compounds.The reason of formation of amorphous phase and the function of SiC particles were explained in details. | Kaijin Huang Changsheng Xie T.M. Yue | 2009 | Journal of Materials Science & Technology2009，25，4： | 8 |
| 19 | Spatial distribution of black carbon emissions in China显示文摘Based on the official statistics,locally measured emission factors,and the vehicular emission factor model most suitable for China,we developed a black carbon(BC)emission inventory for 2008 in China and at a spatial resolution of 0.5°×0.5°.In 2008,the total BC emissions in China were 1604.94 Gg.Industry and the residential sector were the dominant contributors,estimated at 695.03Gg and 636.02 Gg of BC,respectively.Together,these two source types contributed 82.9% of the total emissions.Emissions from transportation were 194.63 Gg,accounting for 12.1% of the total.Since emission contributions from different sectors showed significant spatial diversity among the 31 administrative districts,we divided the districts into four categories:industry contribution district,residential contribution district,industry and residential contribution district,and transportation contribution district.As for energy consumption,coal and biofuel contributed 51.0% and 32.2%,respectively,of the total emissions.Spatially,BC emissions in China were unevenly distributed,higher in the east and lower in the west,corresponding to regional economic development and rural population density.High emission districts,covering 5.7% of the territory,contributed 41.2% of the total emissions.Shanxi,Hebei,Shandong,Henan,and Sichuan were the largest contributors to national BC emissions. | ZHANG Nan QIN Yue XIE ShaoDong | 2013 | Chinese Science Bulletin2013，58，31： | 4 |
| 20 | X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma显示文摘 | Ying Xie Shufeng Liu Yue Zhao Zhanjun Guo Jinsheng Xu | 2014 | Tumor Biology2014，，10： | 3 |
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