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| 1 | A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘 | King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse | 2017 | Journal of Geriatric Cardiology2017，14，12： | 5 |
| 2 | Pandemic of the aging society—sporadic cerebral small vessel disease显示文摘Age-related sporadic cerebral small vessel disease(CSVD)has gained increasing attention over the past decades because of its increasing prevalence associated with an aging population.The widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers’understanding in the in vivo evolution of CSVD,its impact upon the brain,its risk factors,and the mechanisms that explain the various clinical manifestation associated with sporadic CSVD.In this review,we aimed to provide an update on the pathophysiology,risk factors,biomarkers,and the determinants and spectrum of the clinical manifestation of sporadic CSVD. | Alexander Yuk Lun Lau Bonaventure Yiu Ming Ip Ho Ko Bonnie Yin Ka Lam Lin Shi Karen Ka Yan Ma Lisa Wing Chi Au Yannie Oi Yan Soo Thomas Wai Hong Leung Adrian Wong Vincent Chung Tong Mok | 2021 | Chinese Medical Journal2021，，2： | 3 |
| 3 | HBsAg Seroclearance in Chronic Hepatitis B in Asian Patients: Replicative Level and Risk of Hepatocellular Carcinoma显示文摘 | Man–Fung Yuen Danny Ka–Ho Wong James Fung Philip Ip David But Ivan Hung Kevin Lau John Chi–Hang Yuen Ching–Lung Lai | 2008 | Gastroenterology2008，，4： | 2 |
| 4 | Accuracy of Risk Scores for Patients With Chronic Hepatitis B Receiving Entecavir Treatment显示文摘 | Grace Lai–Hung Wong Henry Lik–Yuen Chan Hoi–Yun Chan Pete Chi–Hang Tse Yee–Kit Tse Christy Wing–Hin Mak Stanley King–Yeung Lee Zoe Man–Yi Ip Andrew Ting–Ho Lam Henry Wing–Hang Iu Joyce May–Sum Leung Vincent Wai–Sun Wong | 2013 | Gastroenterology2013，，5： | 2 |
| 5 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 6 | On comparison of jump point detection for an exchange rate series显示文摘The main purpose of this paper is to investigate the detection of jump points of a discontinuous function in the presence of a noise by the wavelet approach. A computing algorithm of our method is proposed and then applied to the daily exchange rate of US Dollar against Deutsche Mark. All the points detected by our method reflect very strong economic and political impacts. Other statistical methods to detect jump points have also been applied to the same exchange rate data. Our proposed method has produced more convincing empirical results than others. | IP Wai-Cheung, WONG Heung, XIE Zhongjie & LUAN YihuiDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China Department of Probability and Statistics, Peking University, Beijing 100871, China | 2004 | Science China Mathematics2004，47，1： | 2 |
| 7 | IL-3,5 and GM-CSF-induced adhesion molecule expression on eosinophils by p38 MAPK and NF-κB显示文摘 | Wong CK Ip WK Lam CWK | 2003 | Am J Respir Cell Mol Biol2003，29，： | 1 |
| 8 | Risk factors associated with life- threatening rickettsial infections 显示文摘 | Lee N Ip M Wong B | 2008 | Am J Trop Med Hyg2008，78，6： | 1 |
| 9 | Comparison of gluteal fasciocutaneous rotational flaps and myocutaneous flaps for the treatment of sacral sores显示文摘 | Wong TC Ip FK | 2006 | Int Orthop2006，30，1： | 1 |
| 10 | Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4,joint macrophages,granulocyte-macrophage colony-stimulating factor,interleukin-6,and leukemia inhibitory factor显示文摘 | Lawlor KE Wong PK Campbell IK van Rooijen N Wicks IP | 2005 | Arthritis Rheum2005，52，12： | 1 |
| 11 | Enhanced production of astaxanthin by the green microalga Chlorella zofingiensis in mixotrophic culture显示文摘 | IP P WONG K CHEN F | 2004 | Process Biochemistry2004，9，11： | 1 |
| 12 | A new framework of simultaneous-fauh diagnosis using pairwise probabilistic multi-label classification for time- dependent modes显示文摘 | VONG C M WONG P K IP W F | 2013 | IEEE Transaction on Industrial Electronics2013，60，8： | 1 |
| 13 | Induction of IL-6 in co-culture of bronchial epithelial cells and eosinophils is regulated by p38 MAPK and NF-kappaB显示文摘 | Wang CB Wong CK Ip WK | 2005 | Allergy2005，11，： | 1 |
| 14 | Acid-forming capacity of lead-zinc mine tailings and its implications for mine rehabilitation显示文摘 | Wong J W C Ip C M Wong M H | 1998 | Environmental Geochemistry and Health1998，20，： | 1 |
| 15 | The recovery of some components of the renin-angiotensin system in the rat pancreas after chronic exposure to hypoxic condition显示文摘 | Ip SP Wong TP Tsai S J | 2003 | J Mol Endocrinol2003，31，3： | 1 |
| 16 | p70 S6 kinase and actin dynamics: A perspec tire显示文摘 | Ip CK Wong AS | 2012 | Spermatogenesis2012，2，1： | 1 |
| 17 | Quantitative ar~alysis of lincomycin in animal tissues and bovine milk by liquid chromatography electrospray ionization tandem mass spectrometry显示文摘 | Sin D W Wong Y Ip A C | 2004 | Journal of Pharmaeeutieal and Biomedical Analysis2004，34，3： | 1 |
| 18 | Association of interleukin-10 pro- moter polymorphisms with systemic lupus erythematosus 显示文摘 | Chong WP Ip WK Wong WH | 2004 | Genes Immun2004，5，6： | 1 |
| 19 | Saralasin, a nonspecific angiotensin Ⅱ receptor antagonist, attenuates oxidative stress and tissue injury in cerulien-induced acute pancreatitis显示文摘 | Ip SP Tsang SW Wong TP | 2003 | Pancreas2003，26，3： | 1 |
| 20 | Virtual brush: A model-based synthesis of Chinese calligraphy显示文摘 | Wong H T F Ip H H S | 2000 | Computer & Graphics2000，24，1： | 1 |
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