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| 1 | 小柴胡汤对体外培养人肝癌细胞株HepG2增殖的影响显示文摘目的探讨小柴胡汤45%乙醇提取物对体外培养人肝癌细胞株HepG2增殖的影响及其可能的机理。方法采用ATP-Lite法测定不同浓度小柴胡汤对体外培养的HepG2增殖的作用,同时利用氧自由基清除能(ORAC)法测定样品的抗氧化活性;以LPS刺激小鼠巨噬细胞RAW264.7产生一氧化氮(NO),Griess法测定NO的终产物亚硝酸盐的含量,观察样品对NO生成的影响。结果小柴胡汤在62.5~500mg/L浓度范围内可以显著抑制HepG2增殖,抑制作用呈剂量相关性,计算半数抑制浓度(IC50)为(90.7±23.7)mg/L。小柴胡汤提取物具有一定的抗氧化活性,其抗氧化能力为阳性对照维生素C的1.3倍。小柴胡汤在3.125~50mg/L浓度范围内均可以显著抑制NO的生成(P<0.05,P<0.01)。结论小柴胡汤具有体外抑制人肝癌细胞株HepG2增殖的作用,其抑制作用可能与其抗氧化活性及抑制NO生成有关。 | 廖晖 David J de Vries Linda K Banbury David N Leach | 2010 | 中国中医药信息杂志2010，17，11： | 7 |
| 2 | Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication显示文摘 | Hilde M van der Schaar Lonneke van der Linden Kjerstin H W Lanke Jeroen R P M Strating Gerhard Purstinger Erik de Vries Cornelis A M de Haan Johan Neyts Frank J M van Kuppeveld | 2012 | Cell Research2012，22，11： | 3 |
| 3 | Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial 1显示文摘 | H.H Hartgrink C.J.H van de Velde H Putter I Songun M.E.T Tesselaar E.Klein Kranenbarg J.E de Vries J.A Wils J van der Bijl J.H.J.M van Krieken | 2004 | European Journal of Surgical Oncology2004，，6： | 2 |
| 4 | Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial显示文摘 | Caroline AH Klazen Paul NM Lohle Jolanda de Vries Frits H Jansen Alexander V Tielbeek Marion C Blonk Alexander Venmans Willem Jan J van Rooij Marinus C Schoemaker Job R Juttmann Tjoen H Lo Harald JJ Verhaar Yolanda van der Graaf Kaspar J van Everdingen Al | 2010 | 2010 (9746)2010，，9746： | 2 |
| 5 | Determination of total, soluble, and insoluble dietary fibre in foods-enzymaticgravimetric methods,MES-TRIR buffer collaborative study显示文摘 | Lee S C Prosky L De Vries J W | 1992 | AOAC Int1992，75，： | 1 |
| 6 | FHPG positron emission tomography for detection of herpes simplex virus(HSV) in experimental HSV encephalitis显示文摘 | Buursma AR de Vries EF Garssen J | 2005 | J Virol2005，79，12： | 1 |
| 7 | Efficient recovery of envi- ronmental DNA for expression cloning by indirect extraction meth- ods显示文摘 | Gabor E M de Vries E J Janssen D B | 2003 | FEMS Microbiol Ecol2003，44，2： | 1 |
| 8 | Iron(Ⅱ) complexes with two and three dialkyldithiocarbamate ligands:Mossbanuer and electronic spectra显示文摘 | de Vries J L K F Trooster J M de Bore E | 1973 | Inorg Chem1973，12，11： | 1 |
| 9 | Detection of npt2Ⅱ(Kanamycinresis-tance)gene in genomes of transgenic plants by marker-rescue transforma-tion显示文摘 | VRIES J D WACKERNAGEL W | 1998 | Mol Gen Genet1998，257，： | 1 |
| 10 | Superoxide production is inversely related to complex I activity in inherited complex I deficiency 显示文摘 | VERKAART S KOOPMAN W J VAN EMST-DE VRIES S E | 2007 | Biochim Biophys Acta2007，1772，3： | 1 |
| 11 | Long-term outcome of uterine artery embolization for symptomatic uterine leiomyomas 显示文摘 | Lohle PN Voogt M J De Vries J | 2008 | J Vasc Interv Radiol2008，19，： | 1 |
| 12 | The World Health Organization Quality ofLife Assessment Instrument ( WHOQOL - 100) : Validation study withthe Dutch version 显示文摘 | De Vries J Van Heck G L | 1997 | European Journal of Psychological Assessment1997，13，3： | 1 |
| 13 | Designing a GPS-based mini wave buoy显示文摘 | Vries J J Bv D | 2007 | International Ocean Systems2007，11，3： | 1 |
| 14 | Alonso's theory of movements: Developments in spatial interaction modeling 显示文摘 | De Vries J J Nijkamp P Rietveld P | 2001 | Journal of Geographical Systems2001，3，3： | 1 |
| 15 | Measles vaccination of nonhuman primates provides partial protection against infection with canine distemper vi- rus显示文摘 | de Vries R D Ludlow M Verburgh R J | 2014 | J Virol2014，88，8： | 1 |
| 16 | Lichen planus is as- sociated with human herpesvirus type 7 replication and infiltration of plasmacytoid dendritic cells 显示文摘 | De Vries HI van Marie J Teunissen MB | 2006 | Br J Dermatol2006，154，2： | 1 |
| 17 | The ther -mal and electrical yield of a PV-thermal collector 显示文摘 | Zondag H A De Vries D W D Van Helden W G J | 2002 | Solar energy2002，72，2： | 1 |
| 18 | Structural protein requirements in equine arteritis virus assembly显示文摘 | Wieringa R de Vries A A vander Meulen J | 2004 | J Virol2004，78，13： | 1 |
| 19 | Dendritic-cell immunothera- py:from ex vivo loading to in vivo targeting显示文摘 | Taeken PJ de Vries I J Torensma R | 2007 | Nat Rev Immunol2007，7，10： | 1 |
| 20 | Innovation in Services in Networks of Organi- zations and in the Distribution of Services 显示文摘 | De Vries E J | 2006 | Research Poli- cy2006，35，7： | 1 |
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