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| 1 | How to Make Capsules Containing Rejuvenators for Their Use in Asphalt Concrete显示文摘Rejuvenators are products designed to restore original properties to oxidized asphalt binders by restoring the original ratio of asphaltenes to maltenes. But,for a rejuvenator to be successful,it must penetrate the pavement surface. Besides,application of a rejuvenator will also reduce the skid resistance of the pavement. To solve this,these rejuvenators can be encapsulated and mixed in asphalt concrete. Once the stress in the capsules reaches a certain threshold,the particles break and the rejuvenator is released,giving back the original properties of the pavement. The objective of this paper is to show how these capsules behave and define the most appropriate testing methods to find their effect on asphalt concrete. For this,two different types of rejuvenators will be encapsulated and their effect on the properties of the capsules investigated. Besides,the release mechanisms of the capsules will be unravelled. | GARCIA A SCHLANGEN E VAN DE VEN M F C | 2010 | 武汉理工大学学报2010，32，17： | 7 |
| 2 | Percutaneous radiofrequency ablation for early hepatocellular carcinoma: Risk factors for survival显示文摘AIM: To evaluate outcomes of radiofrequency ablation(RFA) therapy for early hepatocellular carcinoma(HCC) and identify survival- and recurrence-related factors. METHODS: Consecutive patients diagnosed with early HCC by computed tomography(CT) or magnetic resonance imaging(MRI)(single nodule of ≤ 5 cm, or multi-(up to 3) nodules of ≤ 3 cm each) and who underwent RFA treatment with curative intent between January 2010 and August 2011 at the Instituto do Cancer do Estado de S o Paulo, Brazil were enrolled in the study. RFA of the liver tumors(with 1.0 cm ablative margin) was carried out under CT-fluoro scan and ultrasonic image guidance of the percutaneous ablation probes. Procedure-related complications were recorded. At 1-mo post-RFA and 3-mo intervals thereafter, CT and MRI were performed to assess outcomes of complete response(absence of enhancing tissue at the tumor site) or incomplete response(enhancing tissue remaining at the tumor site). Overall survival and diseasefree survival rates were estimated by the Kaplan-Meier method and compared by the log rank test or simple Cox regression. The effect of risk factors on survival was assessed by the Cox proportional hazard model. RESULTS: A total of 38 RFA sessions were performed during the study period on 34 patients(age in years: mean, 63 and range, 49-84). The mean follow-up time was 22 mo(range, 1-33). The study population showed predominance of male sex(76%), less severe liver disease(Child-Pugh A, n = 26; Child-Pugh B, n = 8), and single tumor(65%). The maximum tumor diameters ranged from 10 to 50 mm(median, 26 mm). The initial(immediately post-procedure) rate of RFAinduced complete tumor necrosis was 90%. The probability of achieving complete response was significantly greater in patients with a single nodule(vs patients with multi-nodules, P = 0.04). Two patients experienced major complications, including acute pulmonary edema(resolved with intervention) and intestinal perforation(led to death). The 1- and 2-year overall survival rates were 82% and 71%, respectively. Sex, tumor size, initial response, and recurrence status influenced survival, but did not reach the threshold of statistical significance. Child-Pugh class and the model for end-stage liver disease score were identified as predictors of survival by simple Cox regression, but only Child-Pugh class showed a statistically significant association to survival in multiple Cox regression analysis(HR = 15; 95%CI: 3-76 mo; P = 0.001). The 1-and 2-year cumulative disease-free survival rates were 65% and 36%, respectively. CONCLUSION: RFA is an effective therapy for local tumor control of early HCC, and patients with preserved liver function are the best candidates. | Luciana Kikuchi Marcos Menezes Aline L Chagas Claudia M Tani Regiane SSM Alencar Marcio A Diniz Venncio AF Alves Luiz Augusto Carneiro D’Albuquerque Flair José Carrilho | 2014 | World Journal of Gastroenterology2014，20，6： | 5 |
| 3 | Durable Asphalt Pavements Are Self Healing显示文摘The traffic volume and the number of heavy vehicles are growing continuously. Considering the continuous traffic flow and the limited time available for road maintenance,it is very important to design a durable pavement system. Asphalt pavements with a healing capability are believed to be very useful since they can extend the pavement service life thanks to rest periods and hot summers. In order to design durable asphalt pavements,research in understanding and upgrading the self-healing capability of bituminous materials in time is of major importance. The self healing capability of bituminous mastic was evaluated in this research with a direct tension healing test. In the test program,different healing times,crack status and modifications were applied. The results indicate that elastic recovery and flow capacity are important factors for the self healing capability of bituminous materials at different crack phases as simulated with the direct tension test. | QIU J VAN DE VEN M F C WU S P YU J Y MOLENAAR A A A | 2010 | 武汉理工大学学报2010，32，17： | 2 |
| 4 | Aherative forms of fit in contingency theory 显示文摘 | Drazin R de Ven A H V | 1985 | Administrative Science Quarterly1985，30，： | 1 |
| 5 | Designing work within and between organizations 显示文摘 | Sinha K K Van de Ven A H | 2005 | Organization Science2005，16，4： | 1 |
| 6 | Structuring cooperative relationships between organizations显示文摘 | Ring P S A H Van De Ven | 1992 | Strategic Management Journal1992，7，13： | 1 |
| 7 | Effects of simvastatin treatment on oxidant/ antioxidant state and ultrastructure of strepto-zotocin-diabetic rat lung显示文摘 | Ozansoy G Güven C Ceylan A | 2005 | Cell Biochem Funct2005，23，6： | 1 |
| 8 | Delayed surgical treatmentof supracondylar humerus fractures in children using a me-dial approach显示文摘 | Eren A Güven M Erol B | 2008 | J Child Orthop2008，2，1： | 1 |
| 9 | Oral Decontam- ination with Chlorhexidine Reduces the Incidence of Ven- tilator-associated Pneumonia显示文摘 | Koeman M Van Der Ven A Hak E | 2006 | Am J Resp Cri Care Med2006，173，12： | 1 |
| 10 | Addition of zoledronic acid to neoadjuvant chemotherapy does not enhance tumor response in patients with HER2 negative stage II/III breast cancer: the NEOZOTAC trial (BOOG 2010 -01 ) 显示文摘 | Charehbili A van de Ven S Smit VT | 2014 | Ann Oncol2014，25，5： | 1 |
| 11 | Learning the Innovation Journey Order out of Chaos?显示文摘 | Cheng Y T Van de Ven A H | 1996 | Organization Science1996，，7： | 1 |
| 12 | Central problems in the management of innovation显示文摘 | Van de Ven A | 1986 | Management Science1986，32，5： | 1 |
| 13 | A collective action mod- el of institutional innovation 显示文摘 | Hargrave T J Van de Ven A H | 2006 | Academy of Management Review2006，31，4： | 1 |
| 14 | Charac- teristics of two-component epoxy modified bitumen 显示文摘 | Xiao Y van de Ven M F C Molenaar A A A | 2010 | Ma- ter Struct2010，44，： | 1 |
| 15 | Developmental processes of cooperative inter organizational relationships 显示文摘 | Ring P S Van de Ven A H | 1994 | Academy of Management Review1994，19，1： | 1 |
| 16 | Preferred conformations of some 2-pyridyl substituted thiourea derivatives显示文摘 | Kascheres A Ven J | 1991 | J Heterocyclic Chem1991，28，： | 1 |
| 17 | The effect of calcium ions on the efficiency of polyethylene oxide-cofactor retention aid systems显示文摘 | Van de Ven T G M Qasaimeh M A Pigeon C | 2007 | Colloids Sur:2007，297，1： | 1 |
| 18 | Different Ap2 proaches to Assessment of Design and Management of Sustain2 able U rban Water System显示文摘 | Michiel A Rijsberman Frans H M. van de Ven | | 0，，03： | 1 |
| 19 | A framework for under- standing the emergence of new industries 显示文摘 | VAN DER VEN A GARUD R | 1989 | Manage- ment and Policy1989，，4： | 1 |
| 20 | An Empirical Evaluation of the Internal Corporate Venturing Process 显示文摘 | Garud R Van de Ven A H | 1992 | Strategic Management Journal1992，，13： | 1 |
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