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| 1 | Single-phase high-entropy intermetallic compounds(HEICs): bridging high-entropy alloys and ceramics显示文摘High-entropy intermetallic compounds(HEICs)were fabricated by mechanical alloying and spark plasma sintering to fill a knowledge gap between the traditional high-entropy alloys(HEAs)and emerging highentropy ceramics(HECs).Notably,several four-or five-component equimolar aluminides,such as the B2-phase(Fe1/5 Co1/5 Ni1/5 Mn1/5 Cu1/5)Al,have been made into single-phase HEICs for the first time.Thermodynamic modeling and a reversible,temperature-dependent,phase-stability experiment suggest that such B2-phase HEICs are entropy-stabilized phases.The structure of these HEICs resembles that of HECs with high-entropy mixing of fo ur or five elements of nearly equal fractions in one and only one sublattice,but with significant(10%)anti-site defects(differing from typical HECs).A new phase stability rule for forming single B2-phase HEICs is proposed.Five additional HEICs of predominantly D022 phases have also been made.This study broadens the families of equimola r,single-phase,high-entropy materials that have been successfully fabricated. | Naixie Zhou Sicong Jiang Timothy Huang Mingde Qin Tao Hu Jian Luo | 2019 | Science Bulletin2019，64，12： | 8 |
| 2 | A novel near-infrared light responsive 4D printed nanoarchitecture with dynamically and remotely controllable transformation显示文摘Four-dimensional (4D) printing is an emerging and highly innovative additive manufacturing process by which to fabricate pre-designed,self-assembly structures with the ability to transform over time.However,one of the critical challenges of 4D printing is the lack of advanced 4D printing systems that not only meet all the essential requirements of shape change but also possess smart,dynamic capabilities to spatiotemporally and instantly control the shape-transformation process.Here,we present a facile 4D printing platform which incorporates nanomaterials into the conventional stimuli-responsive polymer,allowing the 4D printed object to achieve a dynamic and remote controlled,on-time and position shape transformation.A proof-of-concept 4D printed brain model was created using near-infrared light (NIR) responsive nanocomposite to evaluate the capacity for controllable 4D transformation,and the feasibility of photothermal stimulation for modulating neural stem cell behaviors.This novel 4D printing strategy can not only be used to create dynamic 3D patterned biological structures that can spatiotemporally control their shapes or behaviors of transformation under a human benign stimulus (NIR),but can also provide a potential method for building complex self-morphing objects for widespread applications. | Haitao Cui Shida Miao Timothy Esworthy Se-jun Lee Xuan Zhou Sung Yun Hann Thomas J.Webster Brent T.Harris Lijie Grace Zhang | 2019 | Nano Research2019，12，6： | 3 |
| 3 | EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation显示文摘Dear Editor,oll-like receptor 4(TLR4)is a key receptor sensing bacterial lipopolysaccharide(LPS),and is the most investigated member of the Tol-like receptor family(Kawai and Akira,2007;Kayagaki et al,2013;Klein et al.,2015).Cell surface TLR4 expression is determined by the balance between receptor trafficking from the Golgi apparatus to the cell membrane,and internalization of the cell surface receptor into endosomal compartments(Saltoh,2009).In bone mar-row-derived macrophages(BMDM),we observed LPS-in-duced EGFR phosphorylation on the surface of BMDM,and this was inhibited by pretreatment with PD168393 or TAPI-1(Fig.S1).Next,we measured dynamic changes in cell sur-face TLR4 expression after LPS treatment.At6,12,and 24 h after LPS treatment,TLR4 expression on the surface of BMDM was increased^2-,~6-,and^9-fold,respectively,as compared with controls. | Jing Tang Bowei Zhou Melanie JScott Linsong Chen Dengming Lai Erica KFan Yuehua Li Qiang Wu Timothy RBilliar Mark AWilson Ping Wang Jie Fan | 2020 | Protein & Cell2020，11，2： | 2 |
| 4 | Effect of particle degradation on electrostatic sensor measurements and flow characteristics in dilute pneumatic conveying显示文摘 | Wei Chen Jianyong Zhang Timothy Donohua Kenneth Williams Ruixue Cheng Mark Jones Bin Zhou | 2017 | Particuology2017，15，4： | 2 |
| 5 | Predictors and long-term prognosis of early and late recurrence for patients undergoing hepatic resection of hepatocellular carcinoma: a large-scale multicenter study显示文摘Recurrence is common among patients undergoing hepatic resection for hepatocellular carcinoma(HCC),which greatly limits long-term survival.We aimed to identify predictors and long-term prognosis of early and late recurrence after HCC resection.Methods:Multicenter data of patients who underwent HCC resection between 2002 and 2016 were analyzed.Recurrence was divided into early(≤2 years)and late recurrence(>2 years after surgery).Predictors of early and late recurrence,and prognostic factors of post-recurrence survival(PRS)were identified by univariate and multivariate analyses.Results:Among 1,426 patients,554(38.8%)and 348(24.4%)developed early and late recurrence,respectively.Independent predictors associated with early recurrence included preoperative alpha-fetoprotein level>400μg/L,resection margin<1 cm,and tumor size>5.0 cm,multiplicity,macrovascular and microvascular invasion,and satellites of the initial tumor at the first diagnosis of HCC;independent predictors associated with late recurrence included male,cirrhosis,and tumor size>5.0 cm,multiplicity,macrovascular and microvascular invasion,and satellites of the initial tumor.Patients with early recurrence had a lower likelihood of undergoing potentially curative treatments for recurrence(37.2%vs.48.0%,P<0.001)and a worse median PRS(13.5 vs.36.6 months,P<0.001)vs.patients who had late recurrence.Multivariate analysis revealed that early recurrence and irregular postoperative surveillance were independently associated with worse PRS[hazard ratio(HR)=1.250,95%CI:1.016-1.538,P=0.035;and HR=1.983,95%CI:1.677-2.345,P<0.001].Conclusions:Predictors associated with early and late recurrence after curative resection for patients with HCC were generally same,although several did differ.Patients with late recurrence had better long-term survival than patients with early recurrence. | Wen-Tao Yan Chao Li Lan-Qing Yao Hai-Bo Qiu Ming-Da Wang Xin-Fei Xu Ya-Hao Zhou Hong Wang Ting-Hao Chen Wei-Min Gu Jian-Hong Zhong Han Wu Timothy M.Pawlik Wan Yee Lau Feng Shen Tian Yang | 2023 | Hepatobiliary Surgery and Nutrition2023，12，2： | 2 |
| 6 | Myeloperoxidase-Generated Oxidants Modulate Left Ventricular Remodeling but Not Infarct Size After Myocardial Infarction显示文摘 | Nikolay Vasilyev Timothy Williams Marie-Luise Brennan Samuel Unzek Xiaorong Zhou Jay W. Heinecke Douglas R. Spitz Eric J. Topol Stanley L. Hazen Marc S. Penn | 2005 | Circulation2005，，18： | 1 |
| 7 | Variability of Monsoon Climate in East Asia at the End of the Last Glaciation显示文摘 | Zhou Weijian Douglas J. Donahue Stephen C. Porter Timothy A. Jull Li Xiaoqiang Minze Stuiver An Zhisheng Eiji Matsumoto Dong Guangrong | 1996 | Quaternary Research1996，，3： | 1 |
| 8 | A study of the role of ion–molecule chemistry in the formation of sporadic sodium layers显示文摘 | Stephen C. Collins John M.C. Plane Michael C. Kelley Timothy G. Wright Pavel Soldán Timothy J. Kane Andrew J. Gerrard Brent W. Grime Rosie J. Rollason Jonathan S. Friedman Sixto A. González Qihou Zhou Michael P. Sulzer Craig A. Tepley | 2002 | Journal of Atmospheric and Solar-Terrestrial Physics2002，，7： | 1 |
| 9 | RhoA Mutations Identified in Diffuse Gastric Cancer显示文摘 | Jin Zhou Yoku Hayakawa Timothy C. Wang Adam J. Bass | 2014 | Cancer Cell2014，，1： | 1 |
| 10 | Intrinsic GUS-like activities in seed plants显示文摘 | Ching-yeh Hu Paula P. Chee Robert H. Chesney James H. Zhou Paul D. Miller W. Timothy O’Brien | 1990 | Plant Cell Reports1990，，1： | 1 |
| 11 | Highresolution evidence from southern China of an earlyHoloceneoptimum and a mid 2 Holocene dry eventduring the past 18 000years显示文摘 | Zhou Weijian Yu Xuefeng Timothy A J | 2004 | Quaternary Re-search2004，，62： | 1 |
| 12 | High - resolution evidence from southern China of an early Hol- ocene optimum and a mid- Holocene dry event during the past 18,000 years 显示文摘 | ZHOU W J YU X F TIMOTHY A J | 2004 | Quaternary Research2004，62，1： | 1 |
| 13 | Rate and influence of respiratory virus co-infection on pandemic (H1N1) influenza disease显示文摘 | Frank P. Esper Timothy Spahlinger Lan Zhou | 2011 | Journal of Infection2011，，4： | 1 |
| 14 | Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glu- curonosyhransferase 1A1 substrates/inhibitors 显示文摘 | Zhou J Timothy S | 2011 | Drug Metab Dispos2011，39，2： | 1 |
| 15 | High-resolution evidence from southern China of an early Holocene optimum and a mid-Holocene dry event during the past 18,000 years 显示文摘 | Zhou W J Yu X F Timothy Jull A J | 2004 | Quaternary Research2004，62，1： | 1 |
| 16 | Synergistic inactivation of Escherichia coli and MS-2 coliphage by chloramine and cupric chloride显示文摘 | Timothy M Straub Charles P Gerba Xia Zhou | 1995 | Wat Res1995，29，3： | 1 |
| 17 | High-resolution evidence from southern China of an early Holocene optimum and a mid-Holocene dry event during the past 18,000 years显示文摘 | Zhou W J Yu X F Timothy Jull A J | 2004 | Quaternary Research2004，62，1： | 1 |
| 18 | Synergistic inactivation of Esckerichia Coli and MS - 2 coliphage by chloramine and cupric chloride 显示文摘 | Timothy M Straub Charles P Gerba Xia Zhou | 1995 | Water Research1995，29，3： | 1 |
| 19 | Proteomic analysis of protein complexes显示文摘 | Zhou Ming Timothy D Veenstra | 2007 | Proteomics2007，7，16： | 1 |
| 20 | White matter lesion load is associated with resting state functional MRI activity and amyloid pet but not FDG in mild cognitive impairment and early alzheimer’s disease patients显示文摘 | Yongxia Zhou Fang Yu Timothy Q. Duong | 2015 | J. Magn. Reson. Imaging2015，，1： | 1 |
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