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| 1 | Diagnostic and prognostic value of minor elevated cardiac troponin levels for percutaneous coronary intervention-related myocardial injury:a prospective,single-center and double-blind study显示文摘Cardiac troponin-I(cTnI) and-T(cTnT) are sensitive and specific markers of myocardial injury.However,the role of increased cTnI and cTnT in percutaneous coronary intervention(PCI)-related myocardial injury remains controversial.In this prospective,single-center and double-blind study,we aimed to determine the diagnostic and prognostic value of cTnI as well as cTnT(cTns) in PCI-related myocardial injury in a Chinese population.A total of 1,008 patients with stable angina pectoris and non-ST-segment elevation acute coronary syndrome were recruited.The levels of cTnI and cTnT were examined before and after PCI.All patients were followed up for26±9 months to observe the incidence of major adverse cardiac events(MACEs).Our results showed that postPCI cTnI and/or cTnT levels were increased to more than the 99^(th) percentile upper reference limit(URL) in 133(13.2%) patients,among which 22(2.2%) were more than 5×99^(th) percentile URL.By univariate analysis,an elevation in cTns after PCI was not an independent predictor of increased MACEs,HR 1.35(P = 0.33,95%CI:0.74-2.46).In conclusion,our data demonstrate that the incidence of PCI-related myocardial injury is not common in a Chinese population and minor elevated cTns levels may not be a sensitive prognostic marker for MACEs. | Min Zhang Huiwei He Ze-Mu Wang Zhihui Xu Ningtian Zhou Zhengxian Tao Bo Chen Chunjian Li Tiebing Zhu Di Yang Liansheng Wang Zhijian Yang | 2014 | The Journal of Biomedical Research2014，28，2： | 12 |
| 2 | Comparison Between the Audible Noises Generated from Single Corona Source Under DC and AC Corona Discharge显示文摘The corona-generated audible noise(AN)factor is an important consideration in the design and operation of ultrahigh voltage direct current(DC)and alternate current(AC)transmission lines.Due to the differences in discharge process and corona-generated space charges between the DC and AC corona discharge,the audible noise from DC and AC corona has different characteristics.This paper conducts a series of experiments by measuring the time-domain waveforms of the audible noise from a single corona source under DC and AC voltage.Sound pressure pulses are extracted from a correlation analysis,and then a detailed comparison of the basic characteristics of DC and AC corona-generated AN in time-domain and frequency spectrum is given.Results from this paper stand to contribute to an explanation of existing results in AN measurement and analysis from DC and AC transmission lines. | Xuebao Li Xiang Cui Tiebing Lu Donglai Wang Wenzuo Ma Xingming Bian | 2015 | CSEE Journal of Power and Energy Systems2015，1，3： | 8 |
| 3 | Assessment of the immune responses to Treponema pallidum Gpd DNA vaccine adjuvanted with IL-2 and chitosan nanoparticles before and after Treponema pallidum challenge in rabbits显示文摘Syphilis is a multistage,sexually transmitted disease caused by the spirochete,Treponema pallidum(Tp).A significantly high incidence of syphilis has been reported in several countries,including China,and there is an urgent need for the development of efficacious vaccines against syphilis.DNA vaccines are a major breakthrough in the field of vaccination with several advantages over traditional vaccines.Animal model studies of Tp DNA vaccines have not been reported elsewhere but our previous reports describe the development of a single-gene Tp DNA vaccine and preclinical immunization study.In this study,chitosan(CS) nanoparticles were used as a vector and an interleukin-2 expression plasmid(pIL-2) as an adjuvant to enhance a TpGpd DNA vaccine candidate(pTpGpd) in a rabbit Tp skin challenge model.At week 8 after the first immunization,three rabbits from each group were used to determine cytokine measurements and spleen lymphocyte proliferation assay.pTpGpd in combination with pIL-2 wrapped with CS led to the greatest enhancement of anti-TpGpd antibodies and T-cell proliferation.During infection,levels of anti-TpGpd antibodies and T-cell proliferation were measured.Both the serum special IgG and IL-2,interferon-γ were significantly increased by the co-injection of the IL-2 plasmid compared with the injection of TpGpd DNA alone(P<0.05).Furthermore,IL-2 plasmid coinjection efficiently enhanced the antigen-specific lymphocyte proliferation response.Additionally,the ratios of positive skin lesions and ulcer lesions in groups immunized with pTpGpd were significantly lower than those of the pIL-2,CS or pIL-2 mixed with CS control groups(P<0.001).CS vectored and pIL-2 adjuvanted pTpGpd immunized animals exhibited the lowest rates of positive skin tests(8.33%) and ulcer lesions(4.17%) and the fastest recovery(42 d).These experiments indicate that co-injection of a pIL-2 plasmid with pTpGpd DNA vaccine wrapped with CS can significantly strengthen the long-term stability of immune response during infection,efficiently improve the protective effect against T.pallidum spirochetes infection and attenuate syphilitic lesion development. | ZHAO FeiJun ZHANG XiaoHong LIU ShuangQuan ZENG TieBing YU Jian GU WeiMing ZHANG YueJun CHEN Xi WU YiMou | 2013 | Science China(Life Sciences)2013，56，2： | 8 |
| 4 | Modeling of an ionized electric field on the building near the UHVDC transmission line显示文摘In this paper,a 3D upstream finite element method is developed to analyze the ionized electric field around the UHVDC transmission lines including the building near it.The ionized electric field around the building is reduced due to the shielding effect of the building and the shielding distance is about three times its height.The ionized electric field including the human body model on the building and away from the building is also taken into account.The ionized electric field distortion ratio of the human body model is discussed in this paper.The distortion ratios for the positions on the building are less than those on the ground. | ZHEN YongZan CUI Xiang LU TieBing | 2014 | Science China(Technological Sciences)2014，57，4： | 7 |
| 5 | Calculation Model for the Propagation of Audible Noise from High Voltage Transmission Lines显示文摘Audible noise from high voltage transmission lines’ corona discharge has become one of the decisive factors affecting design of high voltage transmission lines, thus it is very important to study the spatial propagation characteristics of audible noise for its accurate pre- diction. A calculation model for the propagation of audible noise is presented in this paper, which is based on the basic equation of the sound wave and can involve the influences of the atmosphere absorption and ground effects. The effects of different ground impedances and the atmospheric attenuation on the distribution of sound pressure level are discussed in this paper. The results show that the atmospheric absorp- tion may increase the attenuation of the audible noise, and the ground surface affects both the amplitude and phase of the sound. The spatial distribution fluctuates considering the ground effects. The atmospheric attenuation and the ground effect are closely related to the frequency of the noise. In the frequency range of the audible noise, the influence of atmospheric attenuation on the spatial propagation characteristics is more obvious in high frequency while ground has significant influences in low frequency. | LI Xuebao CUI Xiang LU Tiebing HE Jiamei | 2013 | 高电压技术2013，39，8： | 6 |
| 6 | Geochemistry of ore-forming fluids and geological significance of the Kuoerzhenkuola gold field in Xinjiang, China显示文摘The Kuoerzhenkuola gold field (including the Kuoerzhenkuola and the Buerkesidai gold deposits) is the most important one in the Sawuer gold belt, northern Xinjiang, China. Iso-topic studies including D, O, He, C, S, Pb and Sr reveal that the ore-forming fluids of the Kuo-erzhenkuola and the Buerkesidai deposits shared the same source: the water of ore fluids was magmatic water and minor meteoric water; the mineralizers and ore materials derived mainly from mantle beneath the island arc, and partially from crust. The ore-forming fluids of two depos-its are a mixture of mantle-derived fluids incorporated by crust-derived fluid, and meteoric water. Based on these results, combined with the consideration of the tectonic setting and geological features, we suggest that the two gold deposits in the Kuoerzhenkuola gold field, Sawur gold belt share the same genesis, and are volcanogenic hydrothermal gold deposits occurring in the same caldera. | SHEN Ping SHEN Yuanchao LIU Tiebing LI Guangming ZENG Qingdong | 2005 | Science China Earth Sciences2005，48，11： | 3 |
| 7 | Cloning and characterization of vernalization-related gene (ver203F) cDNA 3'end显示文摘Based on the cDNA fragment sequence of vernalization-related gene verc203 cloned by differential screening in our lab, the 5′primer has been designed. The cDNA 3′end of ver203 gene (1 197 bp) has been cloned by the RACE method. And it is identified by Northern blotting that its expression is special in vernalization treatment. After comparing the sequence in the nucleotide sequence databases of Genbank, EMBL and DDBJ, the gene has homology with Hordeum vulgare jesmonate-induced protein gene. It is suggested that this gene might be related to the signal transduction mediated by jamonate. | YONG Weidong, CHONG Kang , LIANG Tiebing, XU Zhihong , TAN Kehui and ZHU Zhiqing Research Center for Molecular and Developmental Biology, Institute of Botany, Chinese Academy of Sciences , Beijing 100093, China Shanghai Institute of Plant Physiology , Chinese Academy of Sciences , Shanghai 200032, China Corresponding authors | 1999 | Chinese Science Bulletin1999，44，14： | 3 |
| 8 | Experimental investigation on correlation of corona-induced vibration and audible noise from DC conductor显示文摘In this study,the corona-induced vibration and audible noise(AN)on stranded conductor from positive and negative corona discharges were measured and analysed.The experiments were conducted in a semi-anechoic chamber to reduce the inferences from environment.For the measurement of vibration,the conductor was kept in dry condition without water drops on the conductor,which is different from previous investigations and can reveal the contributions of corona-generated space charges on the corona-induced vibration.Besides,the measurement of vibration on the conductor was performed by using a laser vibrometer which was a non-contact measurement device for measuring the vibration velocity.Furthermore,waveforms of corona-induced vibration and AN were measured simultaneously to analyse the correlation between them.The time and frequency domains characteristics of the vibration velocity and AN from negative and positive corona discharge are carefully analysed and no correlated relationship in time and frequency domains can be found in the two corona effects.It can be concluded that disturbance of air molecules caused by the vibration of conductor does not contribute the corona-generated AN. | Xuebao Li Xiang Cui Tiebing Lu Donglai Wang Renhua Peng Xingming Bian | 2016 | High Voltage2016，1，3： | 3 |
| 9 | Influence of AC Voltage on the Positive DC Corona Current Pulses in a Wire-cylinder Gap显示文摘In the development of hybrid HVDC and HVAC transmission lines,the study of radio interference is an important issue.Positive corona current pulses from high voltage transmission lines are the main source of radio interference.In this paper,the design of a wire-cylinder gap electrode system is presented to study the influence of AC voltage on the characteristics of positive corona current pulses.The study shows that the mode of the current pulses is different from that of either DC or AC corona discharge.Waveform parameters of the pulses,such as rise time,half wave time,duration time,repetition rates,average amplitude,and time intervals of secondary pulses are all statistically analyzed in this study.The empirical formulas for the repetition rates with different AC voltages are presented.A theoretical explanation based on an ion cloud model is given to reveal the mechanism behind the influence of AC voltage on positive corona discharge.The experimental results could provide some references for the prediction of radio interference from hybrid AC/DC transmission lines. | Zhenguo Wang Tiebing Lu Xiang Cui Xuebao Li Huseyin Hiziroglu | 2016 | CSEE Journal of Power and Energy Systems2016，2，4： | 3 |
| 10 | Analysis of Dielectric Particles Charging and Motion in the Direct Current Ionized Field显示文摘When evaluating the electromagnetic environment of high voltage direct current(HVDC)powers lines,a fundamental factor to consider is the ionized field at ground level.China’s rapid industrialization and urbanization has led to haze pollution episodes.Ions generated by the corona discharge on the surface of HVDC power lines can adhere to haze particles,giving rise to variations in space charge density,which then impact the ionized field.In this paper,the charging and motion characteristics of the dielectric particle are investigated.The saturation charge amount of the particle and its contribution to the charge density are calculated in the spherical coordinates using the governing equations of the electric field.The terminal setting velocity is calculated based on the Stokes flow of particles in the gravitational and electrical fields.The mobility of the charged particle is also analyzed.This paper will serve as a valuable reference for the modeling and calculation of the ionized field of HVDC transmission lines,with the presence of dielectric particles. | Zhilong Zou Xiang Cui Tiebing Lu | 2016 | CSEE Journal of Power and Energy Systems2016，2，1： | 3 |
| 11 | Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight显示文摘Neuropeptide Y(NPY) is widely expressed in the central nervous system and influences many physiological processes.It is located within the rat quantitative trait locus(QTL) for alcohol preference on chromosome 4.Alcohol-nonpreferring(NP) rats consume very little alcohol,but have significantly higher NPY expression in the brain than alcohol-preferring(P) rats.We capitalized on this phenotypic difference by creating an Npy knockout(KO) rat using the inbred NP background to evaluate NPY effects on alcohol consumption.Zinc finger nuclease(ZNF) technology was applied,resulting in a 26-bp deletion in the Npy gene.RT-PCR,Western blotting and immunohistochemistry confirmed the absence of Npy mRNA and protein in KO rats.Alcohol consumption was increased in Npy^(+/-) but not Npy^(-/-) rats,while Npy^(-/-) rats displayed significantly lower body weight when compared to Npy^(+/+) rats.In whole brain tissue,expression levels of Npy-related and other alcohol-associated genes,Npy1 r,Npy2r,Npy5 r,Agrp,Mc3 r,Mc4r,Crh and CrMr,were significantly greater in Npy^(-/-) rats,whereas Pome and Crhr2 expressions were highest in Npy^(+/-) rats.These findings suggest that the NPY-system works in close coordination with the melanocortin(MC) and corticotropin-releasing hormone(CRH) systems to modulate alcohol intake and body weight. | Bin Qiu Richard L.Bell Yong Cao Lingling Zhang Robert B.Stewart Tamara Graves Lawrence Lumeng Weidong Yong Tiebing Liang | 2016 | Journal of Genetics and Genomics2016，43，7： | 2 |
| 12 | Electric Field Calculations of Residential Houses near UHVDC Lines Using 3D Reconstruction Method显示文摘Prediction of electric field impact on residential houses is required in the design of UHVDC transmission lines.The calculation of electric field distribution on houses is a 3D problem,however,the effectiveness of some 2D calculation meth-ods has been validated by specific reduced-scale experimental models.The 2D methods are simple in operation and quick in computation compared with the 3D methods.In this paper,the deviation ranges of 2D electric field calculation results on houses are discussed.Then,a 3D electric field reconstruction method is proposed to correct the 2D results according to the size and location of the houses.The 3D electric field distribution on the houses can be obtained based on efficient 2D calculations,and a direct 3D calculation is avoided.Finally,the validity of the calculation methods is verified by the measurement results of a full-scale experimental system. | Donglai Wang Tiebing Lu Xiang Cui Li Xie Luxing Zhao Yong Ju Jiayu Lu | 2019 | CSEE Journal of Power and Energy Systems2019，5，4： | 2 |
| 13 | The role of varied metal protrusions on the conductor surfaces in corona discharge subjected to DC high voltages显示文摘Conductor corona performance is significant in the evaluation of electromagnetic environment for high voltage power transmission lines. The influence of artificial contaminated conductors on corona discharge was studied and turned out to be complicated. The ionized field strength on the corona cage was measured by field mill. Meanwhile, photos of corona plumes were photographed and grayed to quantitate the corona discharge intensity. Subsequently, a calculation model for equivalent electric field strength coefficient was established to evaluate the discharge intensity of conductors in coaxial cylindrical electrode. It could be found the computational results achieved an agreement with the observed experimental phenomena. By means of simulation results, a reasonable explanation was given to the finding that the closer the distance between the two protrusions was, the lower the corona discharge intensity and higher corona inception voltage of the conductors would be. In summary, the distributions of corona sources played an important role in the corona discharge and this work would provide an important reference for the evaluation of corona effects on the surface of contaminated conductors. | XU JiaYu XU Peng ZHANG Qian CUI Xiang BIAN XingMing LU TieBing LI HaiBing | 2018 | Science China(Technological Sciences)2018，61，8： | 2 |
| 14 | A new depth-integrated non-hydrostatic model for free surface flows显示文摘A new depth-integrated model deploying a non-hydrostatic pressure distribution is presented.With the pressure divided into hydrostatic and dynamic components,the horizontal momentum equations were obtained by integrating the Navier-Stokes equations from the bottom to the free surface.The vertical momentum equation,in which the convective and viscosity terms were omitted,was approximated by the Keller-box scheme.The model has two steps.First,the dynamic pressure gradient terms were discretized semi-implicitly and the other terms were in explicit scheme.Second,the velocities expressed as the unknown dynamic pressure were substituted into the continuity equation,resulting in a five-diagonal symmetric matrix linear system that was solved by the conjugate gradient method.The model was validated with the propagation of a solitary wave and sinusoidal wave,indicating that it can predict free surface flows well. | GUO XiaoMing KANG Ling JIANG TieBing | 2013 | Science China(Technological Sciences)2013，56，4： | 2 |
| 15 | Multifractal analysis of resting state fMRI series in default mode network: age and gender effects显示文摘Age-related changes of resting state in default mode network(DMN)may provide new clues to the developing mechanism of normal brain as well as early diagnosis and therapy of some neuropsychiatric disorders.The application of multifractal theory to functional magnetic resonance imaging(fMRI)signals has recently raised increasing attention.We aim to explore the multifractal characteristics underlying the resting state functional magnetic resonance imaging(rs-fMRI)series extracted from DMN,and two issues are mainly discussed:(1)whether there exist multifractals in rs-fMRI series;(2)whether it is possible to distinguish between the different ages or genders by means of multifractal characteristics.Results demonstrated the existence of multifractals in rs-fMRI series in DMN.In addition,slight differences between young subjects and middle-aged or elderly subjects can be successfully detected by Dasa,a modified measure we proposed.Furthermore,it is revealed that the rs-fMRI series from young subjects possess smaller averaged scale index and weaker long range correlation,while those from middle-aged or elderly people present increasing averaged scale index andstronger long range correlation.Whereas no significant statistical differences has been found between male and female group.Our results,therefore,highlight the potential usefulness of multifractal analysis in fMRI series of a certain brain region,and provide important insights into healthy aging in DMN. | Huangjing Ni Xiaolin Huang Xinbao Ning Chengyu Huo Tiebing Liu De Ben | 2014 | Chinese Science Bulletin2014，59，25： | 2 |
| 16 | Analysis of the electric field and ion current density under ultra high- voltage direct-current transmission lines based on finite element method显示文摘 | Lu Tiebing Feng Hail Zhao Zhibin | 2007 | IEEE Transactions on Magnetics2007，43，4： | 1 |
| 17 | Time-domain analysis of transient electromagnetic field generated by aerial busbars above lossy soil显示文摘 | LU Tiebing CUI Xiang YIN Haoliu | 2002 | IEEE Transactions on Magnetics2002，38，2： | 1 |
| 18 | Analysis of the electric field and ion current density under ultra high-voltage direct-current transmission lines based on finite element method显示文摘 | Lu Tiebing Feng Han Zhao Zhibin | 2007 | IEEE Transactions onMagnetics2007，43，4： | 1 |
| 19 | Analysis of the ionized field under HVDC transmission lines in the presence of wind based on upstream finite element method 显示文摘 | Lu Tiebing Feng Han Cui Xiang | 2010 | IEEE Transactions on Magnetics2010，46，8： | 1 |
| 20 | ASurvey on Treatment of Hyperlipidemia inPatients with Coronary Artery Disease显示文摘A retrospective analysis was made on the lipid level and management of those patients who experienced coronary angiography for suspected coronary artery disease and those who suffered from acute myocardial infarction admitted to our department from 1994 to 1997. It revealed: ①Incidence of elevated serum lipids (especially total cholesterol) was higher in patients with CHD than those without CHD; ② No significant difference of serum lipids in patients with single or multi vessel disease was seen except higher serum lipids in patients with multi vessel disease; ③Management for elevated lipid in our cases was not active, even neglected in our clinic practice. Attention should be paid on these problems. | Yang Zhijian(杨志健)\ Yang Bing(杨 兵) Zhu Tiebing(朱铁兵) Huang Jun(黄 峻) Wang Haiyan(王海燕) Cao Kejiang(曹克将)\ Zhang Fumin(张馥敏) Ma Wenzhu Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P. R. China | 1999 | The Journal of Biomedical Research1999，23，2： | 1 |
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