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37篇 您的检索式：作者名="TamerL"

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	题名	作者	年代	出处	被引量
1	Cementomimetics——constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides显示文摘Cementum is the outer-,mineralized-tissue covering the tooth root and an essential part of the system of periodontal tissue that anchors the tooth to the bone. Periodontal disease results from the destructive behavior of the host elicited by an infectious biofilm adhering to the tooth root and left untreated,may lead to tooth loss. We describe a novel protocol for identifying peptide sequences from native proteins with the potential to repair damaged dental tissues by controlling hydroxyapatite biomineralization. Using amelogenin as a case study and a bioinformatics scoring matrix,we identified regions within amelogenin that are shared with a set of hydroxyapatite-binding peptides (HABPs) previously selected by phage display. One 22-amino acid long peptide regions referred to as amelogenin-derived peptide 5 (ADP5) was shown to facilitate cell-free formation of a cementum-like hydroxyapatite mineral layer on demineralized human root dentin that,in turn,supported attachment of periodontal ligament cells in vitro. Our findings have several implications in peptide-assisted mineral formation that mimic biomineralization. By further elaborating the mechanism for protein control over the biomineral formed,we afford new insights into the evolution of protein-mineral interactions. By exploiting small peptide domains of native proteins,our understanding of structure-function relationships of biomineralizing proteins can be extended and these peptides can be utilized to engineer mineral formation. Finally,the cementomimetic layer formed by ADP5 has the potential clinical application to repair diseased root surfaces so as to promote the regeneration of periodontal tissues and thereby reduce the morbidity associated with tooth loss.	Mustafa Gungormus Ersin E Oren Jeremy A Horst Hanson Fong Marketa Hnilova Martha J Somerman Malcolm L Snead Ram Samudrala Candan Tamerler Mehmet Sarikaya	2012	International Journal of Oral Science2012，4，2：	5
2	Molecular biomimetics:nanotechnology through biology显示文摘	Sarikaya M Tamerler C Jen A K		0，，09：	1
3	显示文摘	Tamerler C Dincer S Heidel D	2003	Progress in Organic Coating2003，47，：	1
4	Molecular biomimetics: utilizing nature's molecular ways in practical engineering显示文摘	Tamerler C Sarikaya M	2007	Acta Biomater2007，3，3：	1
5	Materials assembly andformation using engineered polypeptides 显示文摘	Sarikaya M Tamerler C Schwartz DT	2004	Annu Rev Med Res2004，34，1：	1
6	Molecular biomimetics: nanotechnology through biology 显示文摘	Sarikaya M Tamerler C Jen AK	2003	Nat Mater2003，2，9：	1
7	Biomimetic muhifunc- tional molecular coatings using engineered proteins显示文摘	Tamerler C Dincer S Heidel D	2003	Pro Org Coat2003，47，：	1
8	Genetically engineered polypeptides for inorganies: a utility in biological materials sci- ence and engineering显示文摘	Tamerler C Kaear T Sahin D	2007	Mat Sci Eng C2007，27，：	1
9	Production of swainsonine from Metarhizium anisopliae instirred-tank and air-lift reactors 显示文摘	Tamerl Er-Yildir C Adlard M W KESHAVARZ K	1997	Biotechnol Lett1997，19，9：	1
10	Molecular biomimetics: utilizing na- ture's molecular ways in practical engineering显示文摘	Tamerler C Sarikaya M	2007	Aeta Bioma- ter2007，3，：	1
11	Molecular biomimetics: nanotechnology through biology显示文摘	Sarikaya M Tamerler C Jen AK	2003	Nat Mater2003，2，9：	1
12	Molecular biomimetics:nanotechnology through biology显示文摘	SARIKAYA M TAMERLER C JEN AK		0，，：	1
13	Molecular biomimet- ies: nanoteehnology through biology 显示文摘	Sarikaya M Tamerler C Jen AK	2003	Nat Mater2003，2，9：	1
14	Molecular biomimeties:utilizing nature's molecular ways in practical engineering显示文摘	Tamerler C Sarikaya M	2007	Acta Biomateriala2007，3，：	1
15	Materials assembly and formation using engineered polypeptides显示文摘	Sarikaya M Tamerler C Schwartz D T	2004	Annu Rev Mater Res2004，34，：	1
16	Materials specificity and directed assembly of a gold-binding peptide显示文摘	Tamerler C Duman M Oren E E	2006	Small2006，2，：	1
17	Effect of pH on physiology of Metarhizium anisopliae for production of swainsonine显示文摘	Candan Tamerler Millie Ullah Maxwell W Adlard Tajalli Keshavarz	1998	FEMS Microbiology Letters1998，，1：	1
18	Molecular biomimetics:nanotechnology through biology显示文摘	Sarikaya M Tamerler C Jen AK-Y	2003	Nat Mater2003，2，：	1
19	Genetically designed peptide-based molecular materials显示文摘	Tamerler C Sarikaya M	2009	ACS Nano2009，3，：	1
20	Evolutionary engineering of multiple-stress resistant Saccharomyces cerevisiae 显示文摘	Cakar Z P Seker U O Tamerler C	2005	FEMS Yeast Res2005，5，：	1

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