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1抗磷脂综合征诊疗指南显示文摘静脉血栓主要指深静脉血栓形成(deep vein thrombosis,DVT),最常见的部位为腓肠肌静脉,其次为股静脉。深静脉血栓形成相当多见,在美国人群的年发病率为0.1%,每年有超过20万人患DVT,大约10%的DVT患者发生肺栓塞。欧美国家对DVT的诊治与病因研究做了大量的工作,特别是近年来随着临床检验技术与分子生物学的发展,易栓症的各种发病机制已相继发现。约一半的易栓症患者的病因可被确定。 我国尚无DVT的统计资料,一般的印象是低于西方人群,但临床病例日益增多,有的医院已建立了专科病房。总的来讲,我国在心脑血管疾病方面做的工作较多,但对DVT的研究还处于早期阶段,在深度与广度上与国际水平还有较大的距离。另一方面,中国人易栓症发生情况与西方人似有较大的差别。因子VLeiden仅发现两例,凝血酶原G20210A变异尚未见报导。近年来我国血液学会对静脉血栓栓塞的诊断与治疗提出了一系列的指导意见,我们组织翻译了有关资料供有关医务人员参考,以期进一步提高我国DVT的诊断与防治水平,并希望对确定我国DVT诊断与治疗的原则及发展规划有一定的意义。我们将分5个专题介绍这些指导意见,本期介绍的'抗磷脂综合征诊疗指南';'有症状门诊病人深静脉血栓形成的诊断,临床评价和D-二聚体分析可能减少对影像学诊断的需要'。Greaves M Cohen H Machin SJ Mackie I 白艳艳 王兆钺 2004国外医学(输血及血液学分册)2004,27,5:9
2The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase显示文摘Suicide genes have recently emerged as an attractive alternative therapy for the treatment of various types of intractable cancers.The efficacy of suicide gene therapy relies on efficient gene delivery to target tissues and the localized concentration of final geneproducts.Chang DY Yoo SW Hong Y Kim S Kim SJ Yoon SH Cho KG Paek SH Lee YD Kim SS Suh-Kim H 2010中国神经肿瘤杂志2010,8,2:3
3To be Strategically Struggling against Resignation: The Lived Experience of Being Cared for in Forensic Psychiatric Care显示文摘Ulrica H? rberg Reet Sj? gren Karin Dahlberg 2012Issues in Mental Health Nursing2012,,11:2
4Aluminum inhibits the H^+ - ATPase activity by permanently altering the plasma membrane surface potentials in squash roots显示文摘Ahn SJ Sivagum M Osawa H 2001Physiol2001,126,:1
5Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J 2004Proc Natl Acad Sci USA2004,101,26:1
6Endogenous opioids: biology and function 显示文摘Akil H Watson SJ Young E 1984Annu Rev Neurosci1984,7,:1
7Experimental epiretinal proliferation induced by intravitreal red blood cells显示文摘Miller B Miller H Ryan SJ 1986Am J Ophthalmol1986,102,2:1
8Use of primates in research:a global overview显示文摘CARLSSON H SCHAPIRO SJ FARAH I 2004Am J Primatol2004,63,4:1
9The effects of insulin,and insulin-like growth factors Ⅰ and Ⅱ on human ovarian follicles in long-term culture显示文摘Louhio H Hovatta O Sj(o)berg J 2000Mol Hum Reprod2000,6,8:1
10Mammalian genotoxicity assessment of methylene blue in plasma: implications for virus inactivation 显示文摘Wagner SJ Cifone MA Murli H 1995Transfusion1995,35,4:1
11Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia in the UK:A population-based study of incidence and survival显示文摘Passmore SJ Chessells JM Kempski H 2003Br J Haematol2003,121,5:1
12Identification of novel, functional genetic variants in the human matrix metalloproteinase - 2 gene:role of Spl in allele - specific transcriptional regulation显示文摘Price SJ Greaves DR Watkins H 2001J Biol Chem2001,276,10:1
13Endogenous thyrotropin and triiodothyronine concentrations in individuals with thyroid cancer 显示文摘Jonklaas J Nsouli-Maktabi H Soldin SJ 2008Thyroid2008,18,9:1
14Single port access(SPA) chelecystectomy:a completely trznsumbilical approach显示文摘Podolsky ER Rottman SJ Poblete H 2009J Laparoendosc Adv Surg Tech A2009,19,2:1
15Humanization of an anti- vascularer endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders显示文摘Presta LG Chen H O'Connor SJ 1997Cancer Res1997,57,20:1
16Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimer's disease显示文摘Hampel H Teipel SJ Padberg F Brain Research0,,:1
17Neogenin: a multi-functional receptor regulating diverse developmental processes显示文摘Cole SJ Bradford DK Cooper H M 2007Int J Bio- chem Cell Biol2007,39,9:1
18Single port access(SPA) cholecystectnmy: a completely transumbilical approach 显示文摘Podolsky ER Rottman SJ Poblete H 2009J La- paroendose Adv Surg Tech A2009,19,2:1
19Psychometric properties of the korean version of the overactive bladder questionnaire (OAB-q) in a korean population显示文摘Oh SJ Son H Kim SW 2012Int Neurourol2012,16,2:1
20PEDF improves cardiac function in rats with acute myocardial infarction via inhibiting vascular permeability and cardiomyocyte apoptosis显示文摘ZHANG H WANG Z FENG SJ et ol 2015Int J Mol Sci2015,16,3:1
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