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| 1 | Colorectal cancer:Metastases to a single organ显示文摘Colorectal cancer(CRC) is a common malignancy worldwide. In CRC patients, metastases are the main cause of cancer-related mortality. In a group of metastatic CRC patients, the metastases are limited to a single site(solitary organ); the liver and lungs are the most commonly involved sites. When metastatic disease is limited to the liver and/or lungs, the resectability of the metastatic lesions will dictate the management approach and the outcome. Less commonly, the site of solitary organ CRC metastasis is the peritoneum. In these patients, cytoreduction followed by hyperthermic intraperitoneal chemotherapy may improve the outcome. Rarely, CRC involves other organs, such as the brain, bone, adrenals and spleen, as the only site of metastatic disease. There are limited data to guide clinical practice in these cases. Here, we have reviewed the disease characteristics, management approaches and prognosis based on the metastatic disease site in patients with CRC with metastases to a single organ. | Sina Vatandoust Timothy J Price Christos S Karapetis | 2015 | World Journal of Gastroenterology2015，21，41： | 30 |
| 2 | Optoelectronic devices based on two-dimensional transition metal dichalcogenides显示文摘在过去几年里,二维(2D ) 转变金属 dichalcogenide (TMDC ) 材料吸引了研究社区的增加的注意由于他们的唯一的电子、光的性质,从当放大材料从时,联合到 indirect-to-direct bandgap 转变的山谷纺纱对单层多层。这些性质在通讯,计算,和保健的宽广领域里用重要应用正在恳求电子的小说和 optoelectronic 设备的发展。当材料厚度减少从时, TMDC 家庭的特色之一是发生的 indirect-to-direct bandgap 转变对单层多层,它为许多 photonic 应用是有利的。TMDC 也为与对他们也没有格子失配问题的层厚度的原子水平的控制构造大量 heterostructures 表明了崭新的灵活性和通用性。作为结果,在有另外的 2D 材料的联合的分层的 TMDC 为在宽广操作上认识到新奇高效的 optoelectronic 设备有潜力光谱范围。在这篇文章,我们在 2D TMDC 和 optoelectronic 设备研究的合成考察最近的进步。我们也讨论面对 2D 材料的家庭的可伸缩的应用的挑战并且在这些材料为 nanophotonics 技术的未来代提供的机会上提供我们的观点。 | He Tian Matthew L. Chin Sina Najmaei Qiushi Guo Fengnian Xia Hart Wang Madan Dubey | 2016 | Nano Research2016，9，6： | 22 |
| 3 | DA201型大孔吸附树脂分离银杏叶提取物中银杏内酯A、B、C和白果内酯的研究显示文摘 | 何珺 何照范 张勇民 Pierre Sina■ | 2004 | 中草药2004，35，12： | 17 |
| 4 | Two-dimensional MXenes for lithium-sulfur batteries显示文摘Rechargeable lithium-sulfur(Li-S)batteries have attracted significant research attention due to their high capacity and energy density.However,their commercial applications are still hindered by challenges such as the shuttle effect of soluble lithium sulfide species,the insulating nature of sulfur,and the fast capacity decay of the electrodes.Various efforts are devoted to address these problems through questing more conductive hosts with abundant polysulfide chemisorption sites,as well as modifying the separators to physically/chemically retard the polysulfides migration.Two dimensional transition metal carbides,carbonitrides and nitrides,so-called MXenes,are ideal for confining the polysulfides shuttling effects due to their high conductivity,layered structure as well as rich surface terminations.As such,MXenes have thus been widely studied in Li-S batteries,focusing on the conductive sulfur hosts,polysulfides interfaces,and separators.Therefore,in this review,we summarize the significant progresses regarding the design of multifunctional MXene-based Li-S batteries and discuss the solutions for improving electrochemical performances in detail.In addition,challenges and perspectives of MXenes for Li-S batteries are also outlined. | Chuanfang(John)Zhang Linfan Cui Sina Abdolhosseinzadeh Jakob Heier | 2020 | InfoMat2020，2，4： | 16 |
| 5 | Assessment of the anterior chamber parameters after laser iridotomy in primary angle close suspect using Pentacam and gonioscopy显示文摘AIM:To evaluate the changes in the anterior segment parameters of the subjects with primary angle closure suspect(PACS) before and after laser iridotomy(LI) using the Pentacam and gonioscopy. METHODS:Forty-eight eyes of 48 PACS were included.Anterior chamber angle(ACA),central anterior chamber depth(ACD),anterior chamber volume(ACV) and central corneal thickness(CCT) were recorded from the Pentacam before and one month after LI.ACA was graded according to Shaffer classification using Goldmann gonioscopy.RESULTS:ACA increased significantly from 25.59±4.41 to 26.46±4.33 degrees(P=0.009) and ACV changed from 85.97±16.07mm3to 99.25±15.83mm3(P=0.000).The changes in ACD,CCT and intraocular pressure were non-significant(P>0.05).Gonioscopy showed significant widening of the Shaffer angle in 4 quadrants(P<0.001).CONCLUSION:Pentacam can serve as the objective instrument in assessing the efficacy of LI. | Alireza Esmaeili Behzad Barazandeh Sina Ahmadi Alireza Haghi Seyed Mahdi Ahmadi Hosseini Fereshteh Abolbashari | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 8 |
| 6 | Electrochemical measurements used for assessment of corrosion and protection of metallic materials in the field:A critical review显示文摘Corrosion degradation is detrimental to metal structures as it shortens their lifetime and leads to huge economic losses and unexpected disasters.Therefore,the detection and monitoring of corrosion degradation is of great importance.Herein,we briefly review the state-of-the-art electrochemical methods,instrumentation(based on virtual instrumentation),and advanced sensor/probes that are used in the field for the assessment of corrosion damage.Typical corrosion monitoring results,some of which have been obtained at Tianjin University in the past 30 years,for metallic materials and organic coating/metal systems in atmospheric,marine,and soil conditions in the field are presented.Detection methods,data analysis,and theoretical and mathematical models regarding each corrosion system are discussed,and the challenges,problems and possible solutions for each case are suggested.Lastly,future developments,such as wireless,intelligent,and automatic electrochemical measurement,that will augment the present electrochemical methods of evaluating corrosion degradation are summarized. | Da-Hai Xia Cheng-Man Deng Digby Macdonald Sina Jamali Douglas Mills Jing-Li Luo Michael G.Strebl Mehdi Amiri Weixian Jin Shizhe Song Wenbin Hu | 2022 | Journal of Materials Science & Technology2022，，17： | 8 |
| 7 | Progress in the development of vaccines for hepatitis C virus infection显示文摘The hepatitis C virus(HCV), first described in 1989, is now a leading cause of liver cirrhosis and hepatocellular carcinoma. With more than 170 million people infected globally, this virus is a major public health issue. The current standard therapy is based on interferon in combination with ribavirin. This costly therapy often fails to completely clear the infection and is associated with adverse side effects. Recent anti-HCV therapies are interferon-free direct-acting antiviral(DAA) regimens for HCV, including simeprevir, sofosbuvir, and ledipasvir, which have effects on non-structural proteins. DAA regimens have several advantages, such as specifically targeting HCV viral replication, accompanied by very high sustained virological response rates and lower side effects like flu-like syndrome. These facts plus the fact that most HCV cases progress to chronic infection suggest the potential need for an efficient HCV vaccine. Different innovative methods, including methods based on peptide, recombinant protein, DNA, vector-based, and virus-like particles, have been introduced for the development of HCV vaccines. An extensive number of studies have been published on these vaccines, and some vaccines were even tested in clinical trials. In the current review, progress in the development of preventive and therapeutic vaccines against the HCV is reviewed in the context of peptide vaccines, recombinant protein vaccines, HCV-like particle, DNA vaccines and viral vectors expressing HCV genes. | Faezeh Ghasemi Sina Rostami Zahra Meshkat | 2015 | World Journal of Gastroenterology2015，21，42： | 6 |
| 8 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011，17，45： | 6 |
| 9 | Red Ginseng for Type 2 Diabetes Mellitus:A Systematic Review of Randomized Controlled Trials显示文摘客观红人参(RG,人参属人参 C ·迈耶) 是为对待类型 2 糖尿病 mellitus (DM ) 的广泛地使用的植物之一。然而,为类型 2 DM 的 RG 的有效性的系统的评论都不是可得到的。这系统的评论试图与类型 2 DM 在病人为 RG 的有效性评估当前的证据。 | Sina Kim Byung-Cheul Shin Myeong Soo Lee Hyangsook Lee Edzard Ernst | 2011 | Chinese Journal of Integrative Medicine2011，17，12： | 5 |
| 10 | Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study显示文摘当时,新兴的证据建议了 cytoreductive 前列腺切除术(CRP ) 允许优异 oncologic 控制与照顾雄激素剥夺标准的电流相比治疗独自一个。然而,在变形前列腺癌症(mPCa ) 的 cytoreduction 的安全和利益没被证明。因此,我们评估了在最新与 mPCa 诊断的人跟随 CRP 的复杂并发症的发生。在四个第三级的外科的中心从 2006 ~ 2014 经历了 CRP 的 68 个病人的一个总数与为临床上局部性的前列腺癌症(PCa ) 经历了激进的前列腺切除术的 598 个人相比。尿不能自制被定义为任何垫的使用。CRP 有更长起作用的时间(200 min 对 140 min, P < 0.0001 ) 并且更高估计的血损失(250 ml 对 125 ml, P < 0.0001 ) 与控制组相比。然而,外套(8.82% 对 5.85%) 和主要复杂并发症率(4.41% 对 2.17%) 在二个组之间是可比较的。重要地,尿不能自制率在在外科以后 1 年在 CRP 组是显著地更高的(57.4% 对 90.8% , P < 0.0001 ) 。Univariate 逻辑分析证明估计的血损失在 unadjusted 模型两个都是 perioperative 复杂并发症的唯一的独立预言者(或:1.18;95% CI:1.02-1.37;P = 0.025 ) 并且外科调整类型的模型(或:1.17;95% CI:1.01-1.36;P = 0.034 ) 。在结论, CRP 比激进的前列腺切除术更挑战性、与尿不能自制的尤其是更高的发生联系。不过, CRP 是为选择谁的 PCa 病人的一个技术上可行、安全的手术与节点积极或多骨的转移在场当由富有经验的外科医生表现了时。未来的、多机构的临床的试用当前是在进行之中的验证这个概念。 | Dae Keun Kim Jaspreet Singh Parihar Young Suk Kwon Sinae Kim Brian Shinder Nara Lee Nicholas Farber Thomas Ahlering Douglas Skarecky Bertram Yuh Nora Ruel Wun-lae Kim Koon Ho Rha Isaac Yi Kim | 2018 | Asian Journal of Andrology2018，20，1： | 5 |
| 11 | Sodium alendronate loaded poly(L-lactideco-glycolide)microparticles immobilized on ceramic scaffolds for local treatment of bone defects显示文摘Bone tissue regeneration in critical-size defects is possible after implantation of a 3D scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling and healing.Sodium alendronate(Aln),a widely used anti-osteoporosis drug,exhibits strong inhibitory effect on bone resorption performed by osteoclasts.Thus,we propose a new approach for the treatment of bone defects in craniofacial region combining biocompatible titanium dioxide scaffolds and poly(L-lactide-co-glycolide)microparticles(MPs)loaded with Aln.The MPs were effectively attached to the surface of the scaffolds’pore walls by human recombinant collagen.Drug release from the scaffolds was characterized by initial burst(2466% of the drug released within first 24 h)followed by a sustained release phase(on average 5 mg of Aln released per day from Day 3 to Day 18).In vitro tests evidenced that Aln at concentrations of 5 and 2.5 mg/ml was not cytotoxic for MG-63 osteoblast-like cells(viability between 8166% and 9863% of control),but it prevented RANKL-induced formation of osteoclast-like cells from macrophages derived from peripheral blood mononuclear cells,as shown by reduced fusion capability and decreased tartrateresistant acid phosphatase 5b activity(5665% reduction in comparison to control after 8 days of culture).Results show that it is feasible to design the scaffolds providing required doses of Aln inhibiting osteoclastogenesis,reducing osteoclast activity,but not affecting osteoblast functions,which may be beneficial in the treatment of critical-size bone tissue defects. | Lucja Rumian Cornelia Wolf-Brandstetter Sina Roβler Katarzyna Reczynska Hanna Tiainen Havard J.Haugen Dieter Scharnweber Elzbieta Pamula | 2020 | Regenerative Biomaterials2020，7，3： | 5 |
| 12 | Influence of alumina on mineralogy and environmental properties of zinc-copper smelting slags显示文摘An iron-silicate slag, from a zinc-copper smelting process, and mixtures of this slag with 5wt%, 10wt%, and 15wt% alumina addition were re-melted, semi-rapidly solidified, and characterized using scanning electron microscopy equipped with energy dispersive spectroscopy, and X-ray diffraction. The FactSage TM 6.2 thermodynamic package was applied to compare the stable phases at equilibrium conditions with experimental characterization. A standard European leaching test was also carried out for all samples to investigate the changes in leaching behaviour because of the addition of alumina. Results show that the commonly reported phases for slags from copper and zinc production processes (olivine, pyroxene, and spinel) are the major constituents of the current samples. A correlation can be seen between mineralogical characteristics and leaching behaviours. The sample with 10wt% alumina addition, which contains high amounts of spinels and lower amounts of the other soluble phases, shows the lowest leachabilities for most of the elements. | Sina Mostaghel Caisa Samuelsson Bo Bjrkman | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，3： | 4 |
| 13 | Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury显示文摘 | Yumiko Imai Keiji Kuba G. Greg Neely Rubina Yaghubian-Malhami Thomas Perkmann Geert van Loo Maria Ermolaeva Ruud Veldhuizen Y.H. Connie Leung Hongliang Wang Haolin Liu Yang Sun Manolis Pasparakis Manfred Kopf Christin Mech Sina Bavari J.S. Malik Peiris Ar | 2008 | Cell2008，，2： | 4 |
| 14 | Thiopurines in inflammatory bowel disease revisited显示文摘Although a great variety of new drugs have been introduced for the therapy of inflammatory bowel diseases so far,a definite cure of the disease is still out of scope.An anti-inflammatory approach to induce remission followed by maintenance therapy with immunosupressants is still the mainstay of therapy.Thiopurines comprising azathioprine and its active metabolite mercaptopurine as well as tioguanine,are widely used in the therapy of chronic active inflammatory bowel disease(IBD).Their steroid sparing potential and efficacy in remission maintenance are out of doubt.Unfortunately,untoward adverse events are frequently observed and may preclude further administration or be life threatening.This review will focus on new aspects of thiopurine therapy in IBD,its efficacy and safety. | Florian Br Christian Sina Klaus Fellermann | 2013 | World Journal of Gastroenterology2013，19，11： | 3 |
| 15 | Effects of humidity on shear behavior of bamboo显示文摘Bamboo is a naturally occurring biological composite, however its microstructure and hence its properties are very complex compared to the manmade composites. Due to optimization, it can be assumed that the variation in properties along the thickness of the culm be a smooth transition for better bonding strength between layers and to prevent non uniformity in stress concentration. As a consequence,biological structures are complicated and functionally graded. Hence, a realistic model that can capture the mechanical performance of bamboo is valuable in future design of robust multifunctional composites.This paper presents the results of experimental and numerical studies on the torsional(shear) properties of bamboo. The hierarchical and multi-scale structure of bamboo and the distribution of micro-scale fibers are revealed via laser scanning and atomic force microscopy. This information was incorporated into a finite element model to analyze the mechanical behavior of bamboo under torsion and to estimate the shear modulus of bamboo along the fibers. Moreover, the effects of humidity and therefore water content on the mechanical properties of bamboo were evaluated by performing torsion tests on samples maintained in environments with different humidities. Increasing the humidity does not cause a drop in the shear modulus, however, a jump in the shear modulus did occur at around 60% humidity. Results of this study indicate that the highest strength values in samples occurred in environments with humidity levels between 60% and 80% and undergo a significant drop after that. In higher humidities, the samples behave more ductile. | Sina Askarinejad Peter Kotowski Faezeh Shalchy Nima Rahbar | 2015 | Theoretical & Applied Mechanics Letters2015，5，6： | 3 |
| 16 | Phlebotomus papatasi and Meriones libycus as the vector and reservoir host of cutaneous leishmaniasis in Qomrood District,Qom Province,central Iran显示文摘Objective:To determine the sand flies species responsible for most transmission of Leishmania major(L major) to human,as well as to determine the main reservoir hosts of the disease. Methods:Sand flies were collected using sticky papers and mounted in Puri’s medium for species identification.Rodents were trapped by live Sherman traps.Both sand flies and rodents were subjected to molecular methods for detection of leishmanial parasite.Results:Phlebotomus papatasi(P.papatasi) was the common species in outdoor and indoor resting places.Employing PCR technique only three specimens of 150 P.papatasi(2%) were found naturally infected by parasites with a band of 350 bp which is equal to the L major parasite.Forty six rodents were captured by Sherman traps and identified.Microscopic investigation on blood smear of the animals for amastigote parasites revealed 1(3.22%) infected Meriones libycus(M.libycus). Infection of this animal to L.major was confirmed by PCR against rDNA loci of the parasite. Conclusions:This is the first molecular report of parasite infection of both vector(P.papatasi) and reservoir(M.libycus) to L major in the region.The results indicated that P.papatasi was the primary vector of the disease and circulating the parasite between human and reservoirs and M. libycus was the most important host reservoir for maintenance of the parasite source in the area. | Rassi Yavar Saghafipour Abedin Abai Mohammad Reza Oshaghi Mohammad Ali Rafizadeh Sina Mohebail Mehdi Yaaghobi-Ershadi Mohammad Reza Mohtarami Fatemeh Farzinnia Babak | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 3 |
| 17 | Combinatorial design-based quasi-cyclic LDPC codes with girth eight显示文摘This paper presents a novel regular Quasi-Cyclic (QC)Low Density Parity Check (LDPC)codes with columnweight three and girth at least eight.These are designed on the basis of combinatorial design in which subsets applied for the construction of circulant matrices are determined by a particular subset.Considering the nonexistence of cycles four and six in the structure of the parity check matrix,a bound for their minimum weight is proposed.The simtdations conducted confirm that without applying a masking technique,the newly implemented codes have a performance similar to or better than other well-known codes.This is evident in the waterfall region, while their error floor at very low Bit Error Rate (BER)is expected. | Sina Vail Narges Rezvani Majid | 2018 | Digital Communications and Networks2018，4，4： | 3 |
| 18 | Reliability-based robust multi-obj ective optimization of a 5-DOF vehicle vibration model subjected to random road profiles显示文摘Ride and handling are two paramount factors in design and development of vehicle suspension systems.Conflicting trends in ride and handling characteristics propel engineers toward employing multi-objective optimization methods capable of providing the best trade-off designs compromising both criteria simultaneously.Although many studies have been performed on multi-objective optimization of vehicle suspension system,only a few of them have used probabilistic approaches considering effects of uncertainties in the design.However,it has been proved that optimum point obtained from deterministic optimization without taking into account the effects of uncertainties may lead to high-risk points instead of optimum ones.In this work,reliability-based robust multi-objective optimization of a 5 degree of freedom(5-DOF) vehicle suspension system is performed using method of non-dominated sorting genetic algorithm-Ⅱ(NSGA-Ⅱ) in conjunction with Monte Carlo simulation(MCS) to obtain best designs considering both comfort and handling.Road profile is modeled as a random function using power spectral density(PSD) which is in better accordance with reality.To accommodate the robust approach,the variance of all objective functions is also considered to be minimized.Also,to take into account the reliability criterion,a reliability-based constraint is considered in the optimization.A deterministic optimization has also been performed to compare the results with probabilistic study and some other deterministic studies in the literature.In addition,sensitivity analysis has been performed to reveal the effects of different design variables on objective functions.To introduce the best trade-off points from the obtained Pareto fronts,TOPSIS method has been employed.Results show that optimum design point obtained from probabilistic optimization in this work provides better performance while demonstrating very good reliability and robustness.However,other optimum points from deterministic optimizations violate the regarded constraints in the presence of uncertainties. | Abolfazl Khalkhali Morteza Sarmadi Sina Yousefi | 2017 | Journal of Central South University2017，24，1： | 2 |
| 19 | Effect of Low-Pressure Nitrogen DC Plasma Treatment on the Surface Properties of Biaxially Oriented Polypropylene, Poly (Methyl Methacrylate) and Polyvinyl Chloride Films显示文摘In this study, commercial biaxially oriented polypropylene (BOPP), polyvinyl chloride (PVC) and poly (methyl methacrylate) (PMMA) films were treated with nitrogen plasma over different exposure times in a Pyrex tube surrounded by a DC variable magnetic field. The chemical changes that appeared on the surface of the samples were investigated using Fourier transform infrared (FT-IR) spectroscopy and attenuated total reflectance Fourier transform infrared (ATR- FTIR) spectroscopy after treatment for 2 min, 4 min and 6 min in a nitrogen plasma chamber. Effects of the plasma treatment on the surface topographies and contact angles of the untreated and plasma treated films were also analyzed by atomic force microscopy (AFM) and a contact angle measuring system. The results show that the plasma treated films become more hydrophilic with an enhanced wettability due to the formation of some new polar groups on the surface of the treated films. Moreover, at higher exposure times, the total surface energy in all treated films increased while a reduction in contact angle occurred. The behavior of surface roughness in each sample was completely different at higher exposure times. | S. Hamideh MORTAZAVI Mahmood GHORANNEVISS Soheil PILEHVAR Sina ESMAEILI Shamim ZARGHAM S. Ebrahim HASHEMI Hamzeh JODAT | 2013 | Plasma Science and Technology2013，15，4： | 2 |
| 20 | Machine-learning driven global optimization of surface adsorbate geometries显示文摘The adsorption energies of molecular adsorbates on catalyst surfaces are key descriptors in computational catalysis research.For the relatively large reaction intermediates frequently encountered,e.g.,in syngas conversion,a multitude of possible binding motifs leads to complex potential energy surfaces(PES),however.This implies that finding the optimal structure is a difficult global optimization problem,which leads to significant uncertainty about the stability of many intermediates.To tackle this issue,we present a global optimization protocol for surface adsorbate geometries which trains a surrogate machine learning potential on-the-fly.The approach is applicable to arbitrary surface models and adsorbates and minimizes both human intervention and the number of required DFT calculations by iteratively updating the training set with configurations explored by the algorithm.We demonstrate the efficiency of this approach for a diverse set of adsorbates on the Rh(111)and(211)surfaces. | Hyunwook Jung Lena Sauerland Sina Stocker Karsten Reuter Johannes T.Margraf | 2023 | npj Computational Materials2023，，1： | 2 |
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