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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | 急性儿茶酚胺暴露引起可逆的无心脏细胞再生的心肌细胞损伤显示文摘儿茶酚胺增加心脏收缩力,但暴露于高浓度儿茶酚胺或长时间暴露可引起心脏损伤。最近的一项研究表明,小鼠单次皮下注射异丙肾上腺素(isoproterenol,ISO;200 mg/kg)导致急性心肌细胞死亡(8%-10%),但在1个月之内心脏完整修复。心脏再生是通过内源性原癌基因蛋白质cKit+心脏干细胞介导新的心肌细胞形成。 | 刘莉 叶鹏 Wallner M Duran JM Mohsin S Troupes CD Vanhoutte D Borghetti G Vagnozzi RJ Gross P Yu D Trappanese DM Kubo H Toib A Sharp TE Harper SC Volkert MA Starosta T Feldsott EA Berretta RM Wang T Barbe MF Molkentin JD Houser SR | 2016 | 中华高血压杂志2016，24，8： | 4 |
| 3 | Tracheal gas insufflation-pressure control versus volume control ventilation 显示文摘 | Imanaka H Kacmarek RM Ritz R | 1996 | Am J Respir Crit Care Med1996，153，3： | 2 |
| 4 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 5 | Human autoantibodies to carcinoembryonic antigen (CEA) induced by a vaccinia-CEA vaccine 显示文摘 | Conry RM Allen KO Lee H | 2000 | ClinCancer Res2000，6，1： | 2 |
| 6 | HATs on and beyond chromatin 显示文摘 | Chert H Tini M Evans RM | 2001 | Curr Opin Cell Biol2001，13，2： | 1 |
| 7 | Development of clinical dosage forms for a poorly water soluble drug Ⅰ : application of polyethylene glycol-polysorbate 80 solid dispersioncartier system显示文摘 | Dannenfelser RM He H Joshi Y | 2004 | J Pharm Sci2004，93，5： | 1 |
| 8 | Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo)than in secondary glioblastomas显示文摘 | Fujisawa H Reis RM Nakamura M | 2000 | Lab Invest2000，80，1： | 1 |
| 9 | Interrupting reperfusion as a stroke therapy:isehemic postconditioning reduces infarct size after fo- cal ischemia in rats 显示文摘 | Zhao H Sapolsky RM Steinberg GK | 2006 | J Cereb Blood Flow Metab2006，26，9： | 1 |
| 10 | Systemic therapy for metastatic colorectal cancer:current options,current evidence显示文摘 | Kelly H Goldberg RM | 2005 | Clin Oncol2005，23，20： | 1 |
| 11 | Prevalence of frailty in community-dwelling older persons:a systematic review显示文摘 | Collard RM Boter H Schoevers RA | 2012 | J Am Geriatr Soc2012，60，8： | 1 |
| 12 | Assessment of right ventricular functioh using echocardiographic speckle tracking of the tricuspid annular motion:comparison with cardiac magnetic resonance显示文摘 | Ahmad H Mori-Avi V Lang RM | 2011 | Echocardiography2011，2，： | 1 |
| 13 | Comparison of FOLFIRI with or without cetuximab in patients with re- sected stage Ⅲ colon cancer: NCCTG (alliance) inter-group trial N0147显示文摘 | Jocelin H Suresh GN Michelle RM | 2014 | Clin Colorectal Cancer2014，13，2： | 1 |
| 14 | Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology显示文摘 | Dubinsky RM Kabbani H E1-Chami Z | 2005 | Neurology2005，63，6： | 1 |
| 15 | Estimating risk of recurrence in differentiated thyroid cancer after total thyroidectomy and radioactive iodine remnant ablation:using response to therapy variables to modify the initial risk estimates predicted by the new American Thyroid Association staging system显示文摘 | Tuttle RM Tala H Shah J | 2010 | Thyroid2010，20，12： | 1 |
| 16 | (R)-alpha-lipoic acid reverses the age-related loss in GSH redox staus in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis显示文摘 | Su JH Wang H Liu RM | 2004 | Arch Bioehem Biophys2004，423，1： | 1 |
| 17 | Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium显示文摘 | Hudde T Rayner SA Comer RM Weber M Isaacs JD Waldmann H | 1999 | Gene Ther1999，6，5： | 1 |
| 18 | Role of ultrasound in the management of thyroid nodules显示文摘 | Watters DA A H - Huja AT Evans RM | 1992 | Am J Surg1992，164，： | 1 |
| 19 | Hair follicle stem cells显示文摘 | Lavker RM Sun TT Oshima H | 2003 | J Investig Dermatol Symp Proc2003，8，1： | 1 |
| 20 | Myocardial protection by preconditioning of heart with losartan, an angiotensin II type 1-receptor blocker显示文摘 | Sato M Engelman RM Otani H | 2000 | Circulation2000，102，： | 1 |
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