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173篇 您的检索式：作者名="Rainov"

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	题名	作者	年代	出处	被引量
1	STI571对恶性多发性神经胶质母细胞瘤(GBM)的体外抑瘤作用显示文摘目的:研究酪氨酸激酶抑制剂(STI571)对恶性胶质瘤细胞的肿瘤生物学调节作用。方法:用免疫组化法探查血小板源生长因子(PDGF)及其受体在T98G,U87MG,LNZ308,RG四种胶质瘤细胞的表达;MTT法用于检查STI571/TMZ单独或联合应用对胶质瘤细胞的增殖抑制作用,STI571诱导的细胞凋亡途径由流式细胞仪检测,免疫印迹杂交法用来探查STI571抵抗细胞的蛋白激酶网络变化。结果:所用胶质瘤细胞均不同程度的表达PDGF及受体。STI571与TMZ相互协同作用于胶质瘤细胞株T98G;10滋mol/LSTI571可部分抑制所测胶质瘤细胞增殖、可完全抑制其形成集落;高于10滋mol/L浓度的STI571可快速诱导胶质瘤细胞凋亡或坏死;胶质瘤细胞株T98G与STI571长期共培养后,瘤细胞蛋白激酶网络有较大改变。结论:研究表明,PDGF受体酪氨酸激酶抑制剂STI571有较强的抑制恶性胶质瘤细胞(GBM)增殖的作用并可能与其他化疗药物协同抗肿瘤。	任欢李殿俊 Rainov NG	2004	中国肿瘤临床2004，31，15：	3
2	From the cover: neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas显示文摘	Aboody KS Brown A Rainov NG		0，，：	2
3	Direct anterior fixation of odontoid fractures with a hollow spreading screw system显示文摘	Rainov NG Heidecke V Burkert W	1996	Acta Neurochir ( wien)1996，138，：	1
4	Urokinase infusion for severe intraventricular hemorrhage 显示文摘	Rainov NG Burkert WL	1995	Acta Neurochirurgica1995，134，：	1
5	A phase Ⅲ clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme显示文摘	Rainov NG	2000	Hum Gene Ther2000，11，：	1
6	Transcranial Doppler sonography in adult hydrocephalic patients显示文摘	Nikolai G Rainov JB Weise WB	2000	Neurosurg Rev2000，23，1：	1
7	Neural stem cells display extensive tropism for pathology in adult brain:Evidence from intracraniai gliomas显示文摘	Aboody KS Brown A Rainov NG	2000	PNAS2000，97，12：	1
8	Intracellular localization of Herpes simplex virus type 1 thymidine kinase fused to diferent fluorescent proteins depends on choice of fluorescent tag显示文摘	Ariane Sling Andreas Simm Nikolai G Rainov	2002	FEBS Letters2002，527，：	1
9	Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas显示文摘	Aboody KS Brown A Rainov NG	2000	Proc Natl Acad Sci USA2000，97，12：	1
10	Liposome-mediated transfer of the Bcl-2 gene results in neuroprotection after in vivo transient focal cerebral ischemia in an animal model 显示文摘	Cao Y J Shibata T Rainov N G	2002	Gene Therapy2002，9，6：	1
11	Neural stem cells diplay extensive tropism for pathology in adult brain:evidence frointracranial gliomas显示文摘	Aboody KS Brown A Rainov NG	2000	Proc Natl Acad Sci USA2000，97，12：	1
12	Neural stem cells display extensive tropism for pathology in adult brain:Evidence from intracranial gliomas显示文摘	Aboody KS Brown A Rainov NG	2000	Proc Natl Acad Sei USA2000，97，12：	1
13	A phase Ⅲ clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant surgical resection and radiation in adults with previously untreated glioblastoma multiforme显示文摘	RAINOV N G	2000	Hum Gene Ther2000，11，17：	1
14	Results and outcome of neu- rosurgical treatment for extradural metastases in the cervical spine 显示文摘	Heidecke V Rainov NG Burkert W	2003	Acta Neurochir (Wien)2003，145，10：	1
15	A chimeric fusion protein of eytoehrome CYP4Bi and green fluorescent protein for detection of pro - drug activating gene delivery and for gene therapy in malignant glioma显示文摘	Rainov NG Sena- Esteves M Fraefel C	1998	Adv Exp Med Biol1998，451，：	1
16	A Phase Ⅲ Clinical Evaluation of Herpes Simplex Virus Type I Thymidine Kinase and Ganciclovir Gene Therapy as an Adjuvant to Surgical Resection and Radiation in Adults with Previously Untreated Glioblastoma Multiforme显示文摘	Rainov N G	2000	Hum Gene Ther2000，11，17：	1
17	Neural stem cells display extensive tropism for pathology in adult brain:evidence from in tracr- anial gliomas显示文摘	Aboody KS Brown A Rainov NG t al	2000	Proc Natl Acad Sci USA2000，97，12：	1
18	Urokinase infusion for severe in-traventricular hemorrhage 显示文摘	Rainov NG Burkert WL	1995	Acta Neurochir (Wien)1995，134，：	1
19	Neural stem cells display extensive tropism for pathology in adult brain:Evidence from intracranial gliomas 显示文摘	Aboody KS Brown A Rainov NG	2000	Proc Natl Acad USA2000，97，12：	1
20	Ultrasound-guided endoscopic fenestration of the third ventricular floor for non-communicating hydrocephalus显示文摘	Rieger A Rainov NG Sanchin L	1996	Minim Invasive Neurosurg1996，39，1：	1

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