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| 1 | Use of rifaximin in gastrointestinal and liver diseases显示文摘Rifaximin is a broad spectrum oral antibiotic with antimicrobial activity against Gram-positive and Gramnegative aerobic and anaerobic bacteria. It is poorly absorbed and thus has a highly favorable safety profile. Rifaximin has been shown to be effective in the treatment of traveler's diarrhea, functional bloating and irritable bowel syndrome, small bowel bacterial overgrowth and in the prevention of recurrent overt hepatic encephalopathy. In addition, there is emerging evidence for a possible beneficial effect of rifaximin in the treatment of uncomplicated diverticular disease and in the prevention of recurrent diverticulitis. The use of rifaximin is associated with a low incidence of development, or persistence of spontaneous bacterial mutants. Moreover, the development of important drug resistance among extra-intestinal flora during rifaximin therapy is unlikely because of minimal systemic absorption and limited cross-resistance of rifaximin with other antimicrobials. This review addresses the current and emerging role of rifaximin in the treatment of gastrointestinal and liver disorders. | Rani H Shayto Rachel Abou Mrad Ala I Sharara | 2016 | World Journal of Gastroenterology2016，22，29： | 10 |
| 2 | Difficult biliary cannulation: Historical perspective, practical updates, and guide for the endoscopist显示文摘Despite improvements in endoscopic technologies and accessories, development of advanced endoscopy fellowship programs, and advances in ancillary imaging techniques, biliary cannulation in endoscopic retrograde cholangiopancreatography(ERCP) can still be unsuccessful in up to 20% of patients, even in referral centers. Once cannulation has been deemed to be difficult, the risk of post-ERCP pancreatitis and technical failure inherently increases. A number of factors, including endoscopist experience and patient anatomy, have been associated with difficult biliary cannulation, but predicting a case of difficult cannulation a priori is often not possible. Numerous techniques such as pancreatic guidewire and stenting, early pre-cut, and rendezvous may be employed when standard approaches fail. Data regarding the rate of success and adverse events of these techniques have been variable, though most studies suggest that pancreatic duct stenting generally reduces the rate of post-ERCP pancreatitis in instances of difficult biliary cannulation. Here we provide a review on difficult biliary cannulation and discuss how the choice of which techniques to employ and how to best employ them should be individualized and take into account the skill of the endoscopist, the disorder being treated, the anatomy of the patient, and the available biomedical literature. | Rani Berry James Y Han James H Tabibian | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，1： | 8 |
| 3 | Per-oral endoscopic myotomy for achalasia: An American perspective显示文摘Achalasia is an uncommon esophageal motility disorder characterized by the selective loss of enteric neurons leading to absence of peristalsis and impaired relaxation of the lower esophageal sphincter.Per-oral endoscopic myotomy(POEM) is a novel modality for the treatment of achalasia performed by gastroenterologists and surgeons.It represents a natural orifice transluminal endoscopic surgery(NOTES) approach to Heller myotomy.POEM has the minimal invasiveness of an endoscopic procedure that can duplicate results of the surgical Heller myotomy.POEM is conceptually similar to a surgical myotomy without the inherent external incisions and post-operative care associated with surgery.Initial high success and low complications rates promise a great future for this technique.In fact,POEM has been successfully performed on patients with end-stage achalasia as an initial treatment reserving esophagectomy for those without good response.The volume of POEMs performed worldwide has grown exponentially.In fact,surgeons who have performed Heller myotomy have embraced POEM as the preferred intervention for achalasia.However,the niche of POEM remains to be defined and long term results are awaited.We describe our experience with POEM having performed the first POEM outside of Japan in 2009,the evolution of our technique,and give our perspective on its future. | David Friedel Rani Modayil Shahzad Iqbal James H Grendell Stavros N Stavropoulos | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，9： | 8 |
| 4 | A Theory of Economic Development 显示文摘 | Ranis G Fei J H | 1961 | American Economic Review1961，，9： | 1 |
| 5 | Health-care-associated infections:risk factors and epidemiology from an intensive care unit in Northern India显示文摘 | DattaP Rani H Chauhan R | 2014 | Indian J Anaesth2014，58，1： | 1 |
| 6 | Idiopathic infantile arterial calcification with thrombotic mieroangiopathy--a unique case 显示文摘 | Rani H Rao R Rao U | 2010 | Fetal Pediatr Pathol2010，29，6： | 1 |
| 7 | A theory of economic development显示文摘 | Fei J C H Ranis G | 1961 | American Economic Review1961，，57： | 1 |
| 8 | A theory of economic development显示文摘 | Ranis Gustav Fei J C H | 1961 | American Economic Review1961，51，： | 1 |
| 9 | Health-care-associated infections:risk factors and epidemiology from an intensive care unit in Northern India显示文摘 | Datta P Rani H Chauhan R | 2014 | Indian J Anaesth2014，58，1： | 1 |
| 10 | The Ranis-Fei Model of Economic Development: a Reply 显示文摘 | RANIS G FEI J C H | 1963 | American Economic Review1963，53，3： | 1 |
| 11 | A theory of economic development显示文摘 | Ranis G Fei J C H | 1961 | American Economic Review1961，，4： | 1 |
| 12 | Capital-labor Ratios in Theory and in History: Reply 显示文摘 | FEI J C H RANIS G | 1964 | American Economic Review1964，54，6： | 1 |
| 13 | Density Functional Study of the Phase Behavior of Asymmetric Binary Dipolar Mixtures 显示文摘 | Rany G M Klapp S H L | 2004 | Phys Rev E2004，69，： | 1 |
| 14 | Phase Behavior of Bi-Disperse Ferrocolloids 显示文摘 | Rany G M Klapp S H L | 2004 | Phys Rev E2004，70，： | 1 |
| 15 | A Theory of Economic Development显示文摘 | RANIS G FEI J H | 1997 | American Economic Review1997，，51： | 1 |
| 16 | Spatial patterns of DNA replication,protein synthesis,and oxygen concentration within bacterial biofilms reveal diverse physiological states 显示文摘 | Rani S A Pitts B Beyenal H | 2007 | J Baeteril2007，189，： | 1 |
| 17 | A Theory of Economic Development 显示文摘 | Ranis G Fei J C H | 1961 | The American Economic Review1961，51，4： | 1 |
| 18 | A lattice dynamical investigation of the raman and the infrared frequencies of the cubic A2Sn207 pyrochlores 显示文摘 | GUPTA H C BROWN S RANI N | 2001 | International Journal of Inorganic Materials2001，3，7： | 1 |
| 19 | A theory of economic development显示文摘 | Ranis G Fei J C H | 1961 | The American Economic Review1961，51，4： | 1 |
| 20 | Study of predictive controller tuning methods显示文摘 | Rani K Y Unbehauen H | 1997 | Automatica1997，33，12： | 1 |
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