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| 1 | Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis:Systematic review and meta-analysis显示文摘AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and Cochrane databases was conducted. The search terms used included(laparoscopic OR laparoscopy) AND(hepatic or liver) AND(surgery or resection) AND 'hepatocellular carcinoma' AND(cirrhosis or cirrhotic). Furthermore, to widen the search, we also used the 'related articles' section. Studies reporting a comparison of outcomes and methods of open vs laparoscopic hepatic resection for HCC in patients with liver cirrhosis were included. Meta-analysis of results was performed using a random effects model to compute relative risk(RR) and for dichotomous variablesand standard mean differences(SMD) for continuous variables.RESULTS: A total of 420 patients from 4 cohort studies were included in final analysis. Patients undergoing laparoscopic procedures had statistically less blood loss compared to the open cohort, SMD of-1.01(95%CI:-1.23-0.79), P < 0.001, with a reduced risk of transfusion, RR = 0.19(95%CI: 0.09-0.38), P < 0.001. A wider clearance at tumour resection margins was achieved following a laparoscopic approach, SMD of 0.34(95%CI: 0.08-0.60), P = 0.011. No significant difference was noted between laparoscopic and open resection operative times, SMD of-0.15(95%CI: 0.35-0.05), P = 0.142. The overall RR of suffering from postoperative morbidity is 0.25 in favour of the open surgery cohort(95%CI: 0.17-0.37), P < 0.001. Patients under-going laparoscopic surgery had significantly shorter length of stays in hospital compared to the open cohort, SMD of-0.53(95%CI:-0.73 to-0.32), P < 0.001.CONCLUSION: This review suggests that laparoscopic resection of hepatocellular carcinoma in patients with cirrhosis is safe and may provide improved patient outcomes when compared to the open technique. | Ahmed Twaij Philip H Pucher Mikael H Sodergren Tamara Gall Ara Darzi Long R Jiao | 2014 | World Journal of Gastroenterology2014，20，25： | 16 |
| 2 | Methods to Simulate Airborne Sound Transmission at Railway Door Panels with Deterministic Wave Theoretical Approaches显示文摘 | Helmut Schaffer Ernst Pucher | 2013 | 材料科学与工程(中英文A版)2013，3，11： | 2 |
| 3 | Poly: synthesis, crystallinity, and hydrolytic sensitivity in solution and the solid state显示文摘 | Allcock H R Pucher S R | 1994 | Macromolecules1994，27，5： | 1 |
| 4 | Synthesis of Poly(orgnaophosphazenes) with Glycolic Acid Ester and Lactic Acid Ester Side Groups: Prototypes for New Bioerodible Polymers显示文摘 | Alleock H R Pucher S R Scopelianos A G | 1994 | Macromolecules1994，27，1： | 1 |
| 5 | State of the science: chronic periodontitis and systemic health 显示文摘 | Otomo-Corgel J Pucher JJ Rethman MP | 2012 | J Evid Based Dent Pract2012，12，3： | 1 |
| 6 | Infrastructure, programs, and policies to increase bicycling: An international review 显示文摘 | PUCHER J DILL J HANDY S | 2010 | Preventive Medicine2010，50，： | 1 |
| 7 | Surgical ward round quality and impact on variable patient outcomes显示文摘 | Pucher PH Aggarwal R Darzi | 2014 | Ann Surg2014，259，2： | 1 |
| 8 | Bioerodible Polymers with a Phosphorusnitrogen Backbone 显示文摘 | Allcock H R Kwon S Pucher S R | 1990 | Polym Prep1990，31，2： | 1 |
| 9 | State of the sci- ence:chronic periodontitis and systemic health 显示文摘 | Otomo-Corgel J Pucher JJ Rethman MP | 2012 | J Evid Based Dent Pract2012，12，3： | 1 |
| 10 | Cycling Down Under: A Comparative Analysis of Bicycling Trends and Policies in Sydney and Melbourne 显示文摘 | Pucher J Greaves S Garrard J | 2010 | Journal of Transport Geography2010，19，2： | 1 |
| 11 | Bicycling Renaissance in North America显示文摘 | Pucher J Komanoff C Shimek P | 2009 | Transportation Research A2009，33，： | 1 |
| 12 | Poly :synthesis, erystallinity and hydrolytic sensitivity in solution and the solid state 显示文摘 | ALLCOCK H R PUCHER S R SCOPELIANOS A G | 1994 | Macromolecules1994，27，5： | 1 |
| 13 | Poly as substrates for the controlled re- lease of small molecules显示文摘 | ALLCOCK H R PUCHER S R SCOPELIANOS A G | 1994 | Biomaterials1994，15，8： | 1 |
| 14 | Synthesis of poly(orgnaophosphazenes) with glycolic acid ester and lac- tic acid ester side groups:prototypes for new bioerodible polymers 显示文摘 | ALLCOCK H R PUCHER S R SCOPELIANOS A G | 1994 | M acromolecules1994，27，： | 1 |
| 15 | Structure-Activity Relationship in D-,r-A-:r-D-Based Photoinitia- tors for the Two-Photon-Induced Photopolymerization Process 显示文摘 | PUCHER N ROSSPEINTNER A SATZINGER V | 2009 | Macromolecules2009，42，17： | 1 |
| 16 | Paving paths to software radio design显示文摘 | Lee Pucher | 2001 | Communication Systems design2001，7，6： | 1 |
| 17 | Urban transport trends and pol- icies in China and India: impacts of rapid eco- nomic growth显示文摘 | PUCHER J | 2007 | Transport Reviews2007，27，4： | 1 |
| 18 | Kinetics of biochar liquefaction显示文摘 | FEINER R SCHWAIGER N PUCHER H | 2014 | Bioenergy Research2014，7，4： | 1 |
| 19 | Sustainabl M Transport in Freiburg: Lessons from Germany's Environmental Capital 显示文摘 | BUEHLER R PUCHER J | 2011 | International Journal of Sustainable Transportation2011，，5： | 1 |
| 20 | Infrastructure,programs,and policies to increase bicycling:an international review显示文摘 | Pucher J Dill J Handy S | 2010 | Prev Med2010，50，1： | 1 |
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