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51篇 您的检索式:作者名="Patrick Clark"
    题名 作者 年代 出处 被引量
1Two-Year Outcomes After Sirolimus-Eluting Stent Implantation显示文摘Giora Weisz Martin B. Leon David R. Holmes Dean J. Kereiakes Mel R. Clark Barry M. Cohen Stephen G. Ellis Patrick Coleman Carolyn Hill Chunxue Shi Donald E. Cutlip Richard E. Kuntz Jeffrey W. Moses 2006Journal of the American College of Cardiology2006,,7:2
2Interaction between castanospermine an immunosuppressant and cyclosporin A in rat cardiac transplantation显示文摘AIM: To investigate the interaction between castanospermine and cyclosporin A(Cs A) and to provide an explanation for it.METHODS: The alkaloid castanospermine was prepared from the seeds of Castanospermum austral consistently achieving purity. Rat heterotopic cardiac transplantation and mixed lymphocyte reactivity were done using genetically inbred strains of PVG(donor) and DA(recipient). For the mixed lymphocyte reaction stimulator cells were irradiated with 3000 rads using a linear accelerator. Cyclosporin A was administered by gavage and venous blood collected 2 h later(C_2). The blood levels of Cs A(Neoral) were measured by immunoassay which consisted of a homogeneous enzyme assay(EMIT) on Cobas Mira. Statistical analyses of interactions were done by an acceleratedfailure time model with Weibull distribution for allograft survival and logistic regression for the mixed lymphocyte reactivity.RESULTS: Castanospermine prolonged transplant survival times as a function of dose even at relatively low doses. Cyclosporin A also prolonged transplant survival times as a function of dose particularly at doses above 2 mg/kg. There were synergistic interactions between castanospermine and Cs A in the prolongation of cardiac allograft survival for dose ranges of Cs A by castanospermine of(0 to 2) mg/kg by(0 to 200) mg/kg(HR = 0.986; 95%CI: 0.981-0.992; P < 0.001) and(0 to 3) mg/kg by(0 to 100) mg/kg(HR = 0.986; 95%CI: 0.981-0.992; P < 0.001) respectively. The addition of castanospermine did not significantly increase the levels of cyclosporin A on day 3 or day 6 for all doses of Cs A. On the contrary, cessation of castanospermine in the presence of Cs A at 2 mg/kg significantly increased the Cs A level(P = 0.002). Castanospermine inhibited mixed lymphocyte reactivity in a dose dependent manner but without synergistic interaction. CONCLUSION: There is synergistic interaction between castanospermine and Cs A in rat cardiac transplantation. Neither the mixed lymphocyte reaction nor the metabolism of Cs A provides an explanation.Adrian D Hibberd David A Clark Paul R Trevillian Patrick Mcelduff 2016World Journal of Transplantation2016,6,1:2
3Relative sensi- tivity of six estuarine fishes to carbophenothi on chloropyrifosand fenvalerate 显示文摘CLARK J R JAMES M PATRICK J 1985Ecotoxicol Environ Saf1985,10,:1
4Relative sensitivity of six estuarine fishes to carbophenothion, chloropyrifos and fenvalerate显示文摘Clark J R James M Patrick J 1985Ecotoxicol Environ Saf1985,10,:1
5The Nucleus 22-channel cochlear implant system显示文摘Patrick J F Clark G M 1991Ear Hear1991,12,4:1
6A Method for Calibrating Deterministic Forecasts of Rare Events显示文摘Marsh Patrick T Kain John S Lakshmanan Valliappa Clark Adam J Hitchens Nathan M Hardy Jill 2012EN2012,,2:1
7Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual显示文摘S.Eva Singletary Craig Allred Pandora Ashley Lawrence W Bassett Donald Berry Kirby I Bland Patrick I Borgen Gary M Clark Stephen B Edge Daniel F Hayes Lorie L Hughes Robert V.P Hutter Monica Morrow David L Page Abram Recht Richard L Theriault Ann Thor Don 2003Surgical Clinics of North America2003,,4:1
8Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide显示文摘Straub Adam C Clark Katherine A Ross Mark A Chandra Ashwin G Li Song Gao Xiang Pagano Patrick J Stolz Donna B Barchowsky Aaron 2008Journal of Clinical Investigation2008,,12:1
9Relative Sensitivity of Six Estuarine Fishes to Carbophenothion,Chloropyrifos and Fenvalerate 显示文摘Clark J R James M Patrick J 1985Ecotoxicol Environ Saf1985,10,:1
10Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) Study: A Prospective, Randomized Control Trial显示文摘Stephen P. Hoole Patrick M. Heck Linda Sharples Sadia N. Khan Rudolf Duehmke Cameron G. Densem Sarah C. Clarke Leonard M. Shapiro Peter M. Schofield Michael O’Sullivan David P. Dutka 2009Circulation2009,,6:1
11Amniotic fluid concentrations of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 during pregnancy and labor显示文摘Gregory J. Locksmith Penny Clark Patrick Duff George R. Saade Gregory S. Schultz 2001American Journal of Obstetrics and Gynecology2001,,2:1
12Fronto‐temporal alterations within the first 200 ms during an attentional task distinguish major depression, non‐clinical participants with depressed mood and healthy controls: A potential biomarker?显示文摘Andrew. H. Kemp Patrick J. Hopkinson Daniel F. Hermens Donald L. Rowe Alexander L. Sumich C. Richard Clark Wilhelmus Drinkenburg Nadia Abdi Rebecca Penrose Alexander McFarlane Philip Boyce Evian Gordon Leanne M. Williams 2008Hum Brain Mapp2008,,2:1
13Association Between IVUS Findings and Adverse Outcomes in Patients With Coronary Artery Disease显示文摘Patrick A. Calvert Daniel R. Obaid Michael O’Sullivan Leonard M. Shapiro Duncan McNab Cameron G. Densem Peter M. Schofield Denise Braganza Sarah C. Clarke Kausik K. Ray Nick E.J. West Martin R. Bennett 2011JACC: Cardiovascular Imaging2011,,8:1
14Comparison of local sine wave modeling with harmonic phase analysis for the assessment of myocardial strain显示文摘Christopher A. Miller Alex Borg David Clark Christopher D. Steadman Gerry P. McCann Patrick Clarysse Pierre Croisille Matthias Schmitt 2013J. Magn. Reson. Imaging2013,,:1
15Inherited deleterious variants in GALNT12 are associated with CRC susceptibility显示文摘Erica Clarke Roger C. Green Jane S. Green Krista Mahoney Patrick S. Parfrey H. Banfield Younghusband Michael O. Woods 2012Hum Mutat2012,,7:1
16Design and fabrication of the banded electrode array显示文摘CLARK G M SHEPHERD R K PATRICK J F 1983Annals of the New York Academy of Sciences1983,405,:1
17Comparing the Acidity of Hydride and η2-Dihydrogen Complexes of Transition Metals显示文摘 Dean E Wilcox Scott Robert A 1990Inorg Chem1990,29,:1
18Waterborne and sediment - source toxicities of six organic AChEmi- cals to grass shrimp ( Palaemonetes pugio) and amphi- oxus (Branchiostoma caribaeum) 显示文摘Clark J R Patrick J M Moore J C 1987Arch Environ Contain Toxicol1987,,16:1
19Promising strategies to minimize secondary brain injury after head trauma显示文摘Hülya Bayr Robert S. B. Clark Patrick M. Kochanek 20032003 (1 Su)2003,,1:1
20Relative sensitivity of six estuarine fishes to carbophenothion, chloropyrifos and fenvalerate 显示文摘CLARK J R JAMES M PATRICK J 1985Eeotoxieol Environ Saf1985,10,3:1
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