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| 1 | Enterocytes’tight junctions:From molecules to diseases显示文摘Tight junctions(TJs)are structures between cells where cells appear in the closest possible contact.They are responsible for sealing compartments when epithelial sheets are generated.They regulate the permeability of ions,(macro)molecules and cells via the paracellular pathway.Their structure at the electron microscopic level has been well known since the 1970s;however,only recently has their macromolecular composition been revealed.This review first examines the major macromolecular components of the TJs(occludin,claudins,junctional adhesion molecule and tricellulin)and then the associated macromolecules at the intracellular plaque[zonula occludens(ZO)-1,ZO-2,ZO-3,AF-6,cingulin,7H6].Emphasis is given to their interactions in order to begin to understand the mode of assembly of TJs.The functional significance of TJs is detailed and several mechanisms and factors involved are discussed briefly.Emphasis is given to the role of intestinal TJs and the alterations observed or speculated in diverse disease states.Specifically,intestinal TJs may exert a pathogenetic role in intestinal(inflammatory bowel disease,celiac disease)and extraintestinal diseases (diabetes type 1,food allergies,autoimmune diseases).Additionally,intestinal TJs may be secondarily disrupted during the course of diverse diseases,subsequently allowing the bacterial translocation phenomenon and promoting the systemic inflammatory response,which is often associated with clinical deterioration.The major questions in the field are highlighted. | Stelios F Assimakopoulos Ismini Papageorgiou Aristidis Charonis | 2011 | World Journal of Gastrointestinal Pathophysiology2011，2，6： | 8 |
| 2 | 考试测评与语言能力标准对接中的若干问题显示文摘在教育改革背景下,对考试测评与语言能力标准的对接需求显著增加,这不仅体现在对学生语言能力进步的监测上,也体现在标准化考试的使用过程中。将考试的内容和分数与语言能力标准中的不同等级进行对接,可以增强考试分数在不同教育背景下的可解释性。通过对语言测评与CEFR对接研究的分析,讨论考试测评与语言能力框架对接中的一些重要问题,并对《中国英语能力等级量表》与考试的对接提出建议。 | Spiros Papageorgiou 刘洋(译) | 2019 | 中国考试2019，0，8： | 5 |
| 3 | 结肠的腺癌和麦芽淋巴瘤的同时的出现: 一系列三个盒子显示文摘 Simultaneous development of adenocarcinoma and primary B cell lymphoma of mucosa-associated lymphoid tissue(MALT) lymphoma of the colon is rare;only one case has so far been reported out of 13 cases with the coexistence of colonic adenocarcinoma with involvement of the colon by lymphoma.We hereby present three more cases,two females(aged 75 and 71 years) and a male(aged 72 years).All three underwent colectomy based on a preoperative biopsy revealing colonic carcinoma.Histological examination of the resection specimens disclosed a colonic adenocarcinoma in two cases,whereas a tubulovillous adenoma with superficial foci of intraepithelial adenocarcinoma was seen in the thirdcase.Moreover,in all three cases,a coexisting MALT lymphoma was diagnosed in the colon(1 case),in both colon and adjacent lymph nodes(1 case) or in colonic lymph nodes and omentum(1 case).In the last case,a post-operative bone marrow biopsy revealed extensive infiltration of the bone marrow,due to which the patient received postoperative chemotherapy.Diagnostic and treatment issues are briefly discussed. | Theodoros Argyropoulos Periklis Foukas Maria Kefala Panagiotis Xylardistos Sotirios Papageorgiou Nikolaos Machairas Evmorfia Boltetsou Anastasios Machairas Ioannis G Panayiotides | 2012 | World Journal of Gastrointestinal Oncology2012，4，4： | 4 |
| 4 | 分娩所致Valsalva视网膜病变治疗方法的探讨(英文)显示文摘目的:讨论孕妇Valsalva视网膜病变保守或手术治疗方法的选择。方法:一健康孕妇在自然阴道分娩时,右眼底发生黄斑前玻璃体后界膜下出血,本文报道其保守治疗的效果。结果:右眼发病3wk时积血收缩,视力为眼前手动,但病程6mo时,积血溶解,视力恢复至6/5。结论:大多数Valsalva视网膜病变能够自愈。对一些难治性病例,采用Nd:YAG激光行内界膜切开具有一定的效果。而早期玻璃体切除术的增殖膜切除,对预防眼底新生血管膜的发生也具有一定的效果。 | Konstantinos I Papageorgiou Rashmi G Mathew AlexanderS Ioannidis Ajay Sinha Petros S Andreou | 2007 | 国际眼科杂志2007，7，3： | 3 |
| 5 | Strategic supply chain optimization for the pharmaceutical industries显示文摘 | Lazaros G Papageorgiou Guillermo E Rotstein Nilay Shah | 2001 | Ind Eng Chem Res2001，40，1： | 2 |
| 6 | Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity显示文摘Dear Editor,Next-generation sequencing revealed that the majority of the human genome is transcribed but has no coding function.It is estimated that.30000 long noncoding RNAs(lncRNAs)are expressed in humans,but their functions are largely unknown(Suckau et al.,2009;Rinn and Chang,2012;Poller et al.,2013).Consideration of noncoding genomic elements in pathogenetic studies is warranted and enabled by technological advances allowing comprehensive transcriptome mapping of protein-coding genes as well as small and long ncRNAs. | Martina Gast Blanche Schroen Antje Voigt Jan Haas Uwe Kuehl Dirk Lassner Carsten Skurk Felicitas Escher Xiaomin Wang Adelheid Kratzer Katharina Michalik Anna Papageorgiou Tim Peters Madlen Loebel Sabrina Wilk Nadine Althof Kannanganattu VPrasanth Hugo Katus Benjamin Meder Shinichi Nakagawa Carmen Scheibenbogen Heinz-Peter Schultheiss Ulf Landmesser Stefanie Dimmeler Stephane Heymans Wolfgang Poller | 2016 | Journal of Molecular Cell Biology2016，8，2： | 2 |
| 7 | Second Order Nonlinear Evolution Inclusions Ⅱ: Structure of the Solution Set显示文摘我们继续开始在的工作[1 ]( 第二订非线性的进化包括我:存在和松驰结果。Acta 数学科学,英语系列, 21 (5 ) , 977-966 (2005 )) 并且学习在进化三元组的分析框架被定义的第二顺序进化包括的答案集合的结构的性质。为凸的问题,我们证明答案集合是紧缩的 R 未,当为 nonconvex 问题我们证明它是连接的路径时。仅当 multivalued 非线性是凸的,另外,我们证明答案集合被关上珍视。最后,我们由与断绝考虑一个非线性的夸张问题说明结果。关键词进化三元组 - 紧缩的嵌入 - 第二顺序进化 - 紧缩的 R 未 - Pathconnected - 连接 - 连续统 - 夸张问题先生(2000 ) 题目分类 34G20 - | Nikolaos S. PAPAGEORGIOU Nikolaos YANNAKAKIS | 2006 | Acta Mathematica Sinica,English Series2006，22，1： | 2 |
| 8 | Dynamic modeling,assignment,and route guidance in traffic networks显示文摘 | Papageorgiou M | 1990 | Transportation Research Part B1990，24，6： | 1 |
| 9 | Freeway ramp metering: an overview显示文摘 | PAPAGEORGIOU M MESSMER A | 2002 | IEEE Transactions on Intelligent Transportation Systems2002，3，4： | 1 |
| 10 | Absence of Transplacental Passage of the Low Molecular Weight Heparin in Enoxaparin显示文摘 | Dimitrakakis C Papageorgiou P Papageorgiou L | 2000 | Haemostasis2000，30，2： | 1 |
| 11 | Advances in articular cartilage repair 显示文摘 | Beris AE Lykissas MG Papageorgiou CD | 2005 | Injury2005，36，14： | 1 |
| 12 | Simulation studies of integrated corridors control in Glasgow 显示文摘 | DIAKAKI C PAPAGEORGIOU M | 1997 | Transportation Research (Part C)1997，5，3： | 1 |
| 13 | Multiple nontrivial solutions for semilinear elliptic problems显示文摘 | Barletta G Papageorgiou N S | 2009 | Nonlinear Analysis2009，71，10： | 1 |
| 14 | The non-genomic crosstalk between PPAR-gamma ligands and ERK1/2 in cancer cell lines显示文摘 | PAPAGEORGIOU E PITULIS N MSAOUEL P | 2007 | Expert Opin Ther Targets2007，11，8： | 1 |
| 15 | 显示文摘 | Papageorgiou N | 2004 | Coord ChemRev2004，248，： | 1 |
| 16 | Hydrophobic, highly conductive ambient-temperature molten salts显示文摘 | Bomhote P Dias A P Papageorgiou N | 1996 | Inorg Chem1996，35，： | 1 |
| 17 | On the Existence of Periodic Solutions for a Class of Nonlinear Evolution Inclusions 显示文摘 | HU Shou-chuan Papageorgiou Nikolaos S | 1993 | Bollettno U M I1993，7，： | 1 |
| 18 | Periodic solution for nonconvex differential inclusiongs 显示文摘 | HU S PAPAGEORGIOU N S | 1999 | Proc Amer Math Soc1999，127，： | 1 |
| 19 | Effect of synovial fluid,phosphate-buffered saline solution,and water on the dissolution and corrosion properties of CoCrMo alloys as used in orthopedic implants显示文摘 | LEWIS AC KILBURN MR PAPAGEORGIOU I | 2005 | d Biomed Mater Res A2005，73，4： | 1 |
| 20 | Efficiency and equity properties of freeway network-wide ramp metering with AMOC 显示文摘 | Ioannis Markos Papageorgiou | 2004 | Transportation Research Part C2004，12，： | 1 |
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