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| 1 | Surgical management of necrotizing pancreatitis:An overview显示文摘Necrotizing pancreatitis is an uncommon yet serious complication of acute pancreatitis with mortality rates reported up to 15%that reach 30%in case of infection.Traditionally open surgical debridement was the only tool in our disposal to manage this serious clinical entity.This approach is however associated with poor outcomes.Management has now shifted away from open surgical debridement to a more conservative management and minimally invasive approaches.Contemporary approach to patients with necrotizing pancreatitis and/or infectious pancreatitis is summarized in the 3Ds:Delay,Drain and Debride.Patients can be managed in the intensive care unit and any intervention should be delayed.Percutaneous drainage can be utilized first and early in the course of the disease,followed by endoscopic drainage or video assisted retroperitoneoscopic drainage if necrosectomy is deemed necessary.Open surgery is now less frequently performed and should be reserved for cases refractory to any other approach.The management of necrotizing pancreatitis therefore requires a multidisciplinary dynamic model of approach rather than being a surgical disease. | George Kokosis Alexander Perez Theodore N Pappas | 2014 | World Journal of Gastroenterology2014,20,43: | 16 |
| 2 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019,7,17: | 4 |
| 3 | Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high - fat - fed rats : Role of apoptosis, adiponectin and tumour necrosis factor - alpha 显示文摘 | Perez - Matute P Perez - Echarfi N Martinez JA | 2007 | Br J Nutr2007,97,2: | 1 |
| 4 | Ontology specification languages for the semantic Web显示文摘 | Asunción Gomez Perez Oscar Corcho | 2002 | IEEE Intelligent Systems2002,17,1: | 1 |
| 5 | Abacavir dose not influence the rate of sustained virological response in HIV-HCV co- infected patients treated with pegylated interferon and weight adjusted ribavirin显示文摘 | Laufer N Laguno M Perez I | 2008 | Antivir Ther2008,13,7: | 1 |
| 6 | The ex- pression of VvPHYA and VvPHYB transcripts is differently regulat- ed by photoperiod in leaves and buds of grapevines显示文摘 | PEREZ F J KUHN N ORMENO-NUNEZ J RUBIO S | 2009 | Plant Signal- ing & Behavior2009,4,: | 1 |
| 7 | Photoperiod modi es the diurnal expression proele of VvPHYA and VvPHYB transcripts in eld-grown grapevine leaves显示文摘 | KUHN N ORMENO-NUNEZ J JAQUE-ZAMORA G PEREZ F J | 2009 | Journal of Plant Physiology2009,166,: | 1 |
| 8 | Development of a real-time RT-PCR assay for the detection of Potato spindle tuber viroid显示文摘 | Boonham N Gonzalez Perez L Mendez M S | 2004 | Journal of Virological Methods2004,116,: | 1 |
| 9 | The influence of employee motivation on knowledge transfer 显示文摘 | Cruz N M Perez V M Gantero C T | 2009 | Journal of Knowledge Management2009,13,6: | 1 |
| 10 | The many roles of the eukaryotic elongation factor 1 complex显示文摘 | Sasikumar A N Perez W B Kinzy T G | | 0,,04: | 1 |
| 11 | Could targeting bone delay cancer progression? Potential mechanisms of action of bisphosphonates显示文摘 | Aft R Perez JR Raje N | | 0,,2: | 1 |
| 12 | Laser nitriding of an intermetallic TiA1 alloy with a diode laser 显示文摘 | Perez M G Harlan N R Zapirain F | 2006 | Surface and Coatings Technology2006,200,17: | 1 |
| 13 | Diffuse emission of carbon dioxide from Cerro Negro volcano, Nicaragua, central America 显示文摘 | Salazar J M L Hernfindez P A Perez N M | 2001 | Geophysical Research Letters2001,28,22: | 1 |
| 14 | Non- Frankla actinomycetes isolated from surface-sterilized roots of Casuarina equisetifolia fix nitrogen显示文摘 | Valdes M Perez N O Estrada-de Los Santos P | 2005 | App! Environ Microbiol2005,71,1: | 1 |
| 15 | Does the presence of hepatitis virus B and C influence the evolution of diffuse large B-cell lymphoma?显示文摘 | Judit Rubio Fernando Franco Antonio Sá nchez Blanca Cantos Miriam Mé ndez Virginia Calvo Constanza Maximiano David Perez Isabel Millá n Margarita Sá nchez-Beato Mariano Provencio | 2015 | Leukemia & Lymphoma2015,,6: | 1 |
| 16 | Elecrochemical corrosion of an Al-Mg-Cr-Mn alloy containing Fe and Si inhibited alkaline solutions显示文摘 | ADAM A M M M BORRAS N PEREZ E | 1996 | Journal of Power Sources1996,58,: | 1 |
| 17 | A better cell cycle target for gene therapy of eolorectal cancer: eyelin G显示文摘 | Perez R Wu N Klipfel AA | 2003 | J Gastrointest Surg2003,7,7: | 1 |
| 18 | T- cell regulation in chronic paranasal sinus disease显示文摘 | VAN BRUAENE N PEREZ NOVO C A BASINS KIT M | 2008 | J Allergy Clin Immunol2008,121,6: | 1 |
| 19 | Detection of fracture orientation using azimuthal AVO responses显示文摘 | Perez M A Gibson R L Toksoz N | 1999 | Geophysics1999,64,4: | 1 |
| 20 | Damping behavior of 6061 Al/Cr metal matrix composites显示文摘 | Perez R J Zhang J Gungor M N | 1993 | Metall Trans1993,24,: | 1 |