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| 1 | 高光谱遥感在农作物长势监测中的应用显示文摘该研究是加拿大Saskatchewan Scott农作物轮作系统(ACS)研究的一部分。研究始于1994年,历时18a,评价9个可耕种农作物产量系统的可靠性。由3种处理水平(organic,reduced,high)和3种作物多样性水平(low,diversified annual grains,diversified annual perennials)结合而产生的9个农作物产量系统,被用于监测和评价加拿大牧场不同处理和不同作物种植轮作下可耕种农作物的产量。在2003年生长季共收集了3次叶面积指数和光谱反射率的数据:生长季前期(6月)、生长季旺盛期(7月)、生长季后期(8月)。叶面积指数是由LAI-2000植物冠层分析仪监测的,光谱测量是由覆盖了350-2500 nm波长范围共2215个波段的ADS便携式高光谱仪完成的。结果显示,光学测量可以用于监测农作物生长状况的差异。从生长季的早期到中期,光谱和叶面积指数在不同处理下有显著差异。7月中期是用遥感资料监测农作物长势的最佳季节;红光波段与近红外波段反射率的比值和基于这两个波段构造的归一化植被指数,是检测农作物长势的最佳植被指数。 | 郑有飞 Guo X Olfert O Brandt S Thomas G Weiss R Sproule L | 2007 | 气象与环境科学2007，30，1： | 22 |
| 2 | Mechanisms of hepatocellular carcinoma progression显示文摘Hepatocellular carcinoma(HCC) is the most common primary malignancy of the liver. It is the second leading cause of cancer-related deaths worldwide, with a very poor prognosis. In the United States, there has been only minimal improvement in the prognosis for HCC patients over the past 15 years. Details of the molecular mechanisms and other mechanisms of HCC progression remain unclear. Consequently, there is an urgent need for better understanding of these mechanisms. HCC is often diagnosed at advanced stages, and most patients will therefore need systemic therapy, with sorafenib being the most common at the present time. However, sorafenib therapy only minimally enhances patient survival. This review provides a summary of some of the known mechanisms that either cause HCC or contribute to its progression. Included in this review are the roles of viral hepatitis, non-viral hepatitis, chronic alcohol intake, genetic predisposition and congenital abnormalities, toxic exposures, and autoimmune diseases of the liver. Well-established molecular mechanisms of HCC progression such as epithelial-mesenchymal transition, tumor-stromal interactions and the tumor microenvironment, cancer stem cells, and senescence bypass are also discussed. Additionally, we discuss the roles of circulating tumor cells,immunomodulation, and neural regulation as potential new mechanisms of HCC progression. A better understanding of these mechanisms could have implications for the development of novel and more effective therapeutic and prognostic strategies, which are critically needed. | Olorunseun O Ogunwobi Trisheena Harricharran Jeannette Huaman Anna Galuza Oluwatoyin Odumuwagun Yin Tan Grace X Ma Minhhuyen T Nguyen | 2019 | World Journal of Gastroenterology2019，25，19： | 21 |
| 3 | 高血压患者脑小血管病变化对认知功能的影响显示文摘高血压是脑小血管病进展与认知功能障碍的主要危险因素之一。该研究旨在探讨高血压患者脑小血管病损伤变化与认知功能减退及轻度认知功能障碍的关系。该研究的数据从ISSYS队列(探讨高血压无症状性脑卒中:一个磁共振成像研究)中获得,其是一项纵向人群研究,纳入基线无痴呆及脑卒中,年龄50~70岁的高血压患者。 | Jiménez-Balado J Riba-Llena I Abril O Garde E Penalba A Ostos E Maisterra O Montaner J Noviembre M Mundet X Ventura O Pizarro J Delgado P 赵狄 练桂丽 | 2019 | 中华高血压杂志2019，27，2： | 15 |
| 4 | 肾管状囊性癌临床病理和分子特征显示文摘 | Yang X J Zhou M Hes O 张仁亚(摘译) | 2008 | 临床与实验病理学杂志2008，24，1： | 13 |
| 5 | Gastroesophageal reflux: the features in elderlypatients显示文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients. | Huang X Zhu HM Deng CZ Porro GB Sangaletti O Pace F | 1999 | World Journal of Gastroenterology1999，5，5： | 12 |
| 6 | 肾脏的小管状囊性癌:临床病理和分子学特征显示文摘 | Yang X J Zhou M Hes O 黄文斌(摘译) | 2008 | 临床与实验病理学杂志2008，24，3： | 9 |
| 7 | 胰腺肝样癌显示文摘 | Hammeed O Haodong X Saddeghi S 刘飞飞(摘译) 张仁亚(审校) | 2007 | 临床与实验病理学杂志2007，23，1： | 7 |
| 8 | 镁铁-超镁铁质层状岩体锆石原位Hf-O同位素研究新进展显示文摘锆石是一种高温、难熔的稳定矿物。它不易受后期高温热事件的改造,且能够保留有效的Hf同位素初始比值,同时锆石O同位素可用物识别地幔交代的物质组成和过程。因此,镁铁质岩石中的锆石原位U/Pb-Hf-O同位素常可用来限定岩浆事件时代、地幔源区性质及演化过程。该理论应用的前提是锆石Hf同位素体系未受扰动,与其母岩浆达到同位素平衡。 | 袁超 Wang M X Nebel O Wang C Y | 2016 | 矿物岩石地球化学通报2016，0，3： | 7 |
| 9 | The experimental study of genetic engineering human neural stem cells mediated by lentivirus to express multigene显示文摘 | Cai PQ Tang X Lin YQ Martin O Sun GY Xu L Yang YK Zhou TH | 2006 | 中国生物学文摘2006，20，5： | 6 |
| 10 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 11 | Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension显示文摘 | Sitbon O Humbert M Jais X | | 0，，： | 2 |
| 12 | Pathogenetic factors affecting gastroesophageal refluxin patients with esophagitis and concomitant duodenal ulcer:a multivariate analysis显示文摘Pathogeneticfactorsafectinggastroesophagealrefluxinpatientswithesophagitisandconcomitantduodenalulcer:amultivariateanalysisZH... | Zhu, HM Huang, X Deng, CZ Porro, GP Pace, F Sangaletti, O | 1998 | World Journal of Gastroenterology1998，4，2： | 2 |
| 13 | RNA编辑介导了COPA的功能转换显示文摘【据Journal of Hepatology 2021年1月报道】RNA编辑介导了COPA的功能转换--最新发现的肝细胞癌发生机制(作者Song Y等)RNA编辑与RNA序列中的核苷酸变化相关。近期有研究报道了异常腺苷和肌苷的RNA编辑与癌症相关。目前为止,很少发现具有重要功能的蛋白质编辑靶点与肝癌相关。来自新加坡国立大学的Song等研究了蛋白质的编辑靶点COPA(coatomer亚基α)在肝细胞癌(HCC)中的作用。 | SONG Y AN O REN X 张海玲 胡玉琳 | 2021 | 临床肝胆病杂志2021，37，2： | 2 |
| 14 | The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue 显示文摘 | XIE X CLAUSEN O P DE ANGELIS P | 1999 | Cancer1999，86，6： | 1 |
| 15 | Anoikis and metastatic potential of cloudman S91 melanoma cells显示文摘 | Sanchez-Sweatman O Huang X | 2001 | Cancer Res2001，61，4： | 1 |
| 16 | A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 显示文摘 | Park H Li Z Yang X O | 2005 | Nat Immunol2005，6，11： | 1 |
| 17 | Age-dependent reductions in the level of glial fibrillary acidic protein in the prefrontal cortex in major depression显示文摘 | Si X Miguel-Hidalgo J J O′Dwyer G | 2004 | Neuropsychopharmacology2004，29，： | 1 |
| 18 | Tyndallometry with the laser flare cell meter in intraocular in flammation 显示文摘 | Kuchle M Nguyen N X Naumann G O | 1994 | Ophthalmologe1994，91，2： | 1 |
| 19 | Recent Developments in the Research of Shape Memory Alloys显示文摘 | Kazuhiro O Ren X | 1999 | Intermetallics1999，7，： | 1 |
| 20 | A population-based case-control study of the Arg399Gln polymorphism in DNA repair gene XRCC 1 and risk of breast cancer显示文摘 | SHU X O CAI Q GAO Y T | 2003 | Cancer Epidemiol Biomarkers Prey2003，12，12： | 1 |
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