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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
| 3 | Flower pollination algorithm applied for different economic load dispatch problems显示文摘 | PRATHIBA R MOSES M B SAKTHIVEL S | 2014 | International Journal of Engineering and Technology2014，6，2： | 1 |
| 4 | Advancing the field of drug delivery: taking aim at cancer 显示文摘 | Moses M A Brem H Langer R | 2003 | Cancer Cell2003，4，5： | 1 |
| 5 | X-ray photoelectron spectroscopy of alkylamine-silanes bound to metal oxide electrodes显示文摘 | Moses P R Wier L M Lennox J C | 1978 | Anal Chem1978，50，： | 1 |
| 6 | Risk of using platelet rich plasma gel显示文摘 | Moses M Karpathin M | 1998 | J oral maxillofac Surg1998，56，3： | 1 |
| 7 | Mrdiagnosis of tears of anterior cruciate ligament of the knee:importance of ancillary findings显示文摘 | Mccauley TR Moses M Kier R | 1994 | AJR1994，162，1： | 1 |
| 8 | Heparinase inhibits neovascularization显示文摘 | Moses M Nugent M | 1994 | Proceedings of the National Academy of Sciences of the United States of America1994，91，： | 1 |
| 9 | Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer 显示文摘 | Roy R Yang J Moses M A | 2009 | J Clin Oncol2009，27，31： | 1 |
| 10 | Risks of using platelet rich plasma gel显示文摘 | Landesberg R Moses M Karpatkin M | | 0，，09： | 1 |
| 11 | Two-dimensional Prony Modeling and Parameter Estimation显示文摘 | J J Sacchini W M Steedly R L Moses | 1993 | IEEE Trans on Signal Processing1993，41，11： | 1 |
| 12 | The combination of insulin-like growth factor 1and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1diabetes:evidence for in vivo biological activity显示文摘 | CLEMMONS D R MOSES A C MCKAY M J et el | 2000 | J Clin Endocrinol Metab2000，85，： | 1 |
| 13 | Critical analysis of the theory of the double cantilever method of measuring fracture-surface energies 显示文摘 | Wiederhorm S M Shorb A M Moses R L | 1968 | Journal of Applied Physics1968，39，3： | 1 |
| 14 | High resolution exponential modeling of fully polarizod radar remms显示文摘 | W M Steadly R L Moses | 1991 | IEEE Trans on AES1991，27，3： | 1 |
| 15 | Genomic surveillance elucidates Ebola virus origin and transmission during the 2014outbreak显示文摘 | Gire S K Goba A Andersen K G Sealfon R S Park D J Kanneh L Jalloh S Momoh M Fullah M Dudas G Wohl S Moses L M Yozwiak N L Winnicki S Matranga C B Malboeuf C M Qu J Gladden A D Schaffner S F Yang X Jiang P P Nekoui M Colubri A Coomber M R Fonnie M Moigboi A Gbakie M Kamara F K Tucker V Konuwa E Saffa S Sellu J Jalloh A A Kovoma A Koninga J Mustapha I Kargbo K Foday M Yillah M Kanneh F Robert W Massally J L Chapman S B Bochicchio J Murphy C Nusbaum C Young S Birren B W Grant D S Scheiffelin J S Lander E S Happi C Gevao S M Gnirke A Rambaut A Garry R F Khan S H Sabeti P C | 2014 | Science2014，345，6202： | 1 |
| 16 | The combination of insulin-like growth factor I and insulin like growth factor binding protein-3 reduces insulin requirements in insulin-dependent type I diabetes: evidence for in vivo biological activity显示文摘 | Clemmons D R Moses A C Mckay M J | | J Clin0，，： | 1 |
| 17 | Increased incidence of matrix matalloproteinases in urine of cancer patients显示文摘 | Wiederschain D Loughlin K R | 1998 | Cancer Research1998，58，： | 1 |
| 18 | MR diagnosis of tears ofanteriorcruciate ligament of the knee:importance of ancillary findings显示文摘 | McCauley TR Mose M Kier R | 1994 | AJR1994，162，1： | 1 |
| 19 | Squamous cell carcinoma of the esophagus associated with peptic duodenal ulcer显示文摘 | Wong R K H Peura D A | 1983 | Am J Gastroenterol1983，78，11： | 1 |
| 20 | Matrix metalloprotemases as novel biomarkers and potential therapeutic targets in human cancer 显示文摘 | Roy R Yang J Moses M A | 2009 | J Clin Oncol2009，27，： | 1 |
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