|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Accelerated restructuring in rural China fueled by ‘increasing vs. decreasing balance’ land-use policy for dealing with hollowed villages显示文摘 | Hualou Long Yurui Li Yansui Liu Michael Woods Jian Zou | 2011 | Land Use Policy2011，，1： | 4 |
| 2 | Cardiovascular Function and Treatment in β-Thalassemia Major: A Consensus Statement From the American Heart Association显示文摘 | Dudley J. Pennell James E. Udelson Andrew E. Arai Biykem Bozkurt Alan R. Cohen Renzo Galanello Timothy M. Hoffman Michael S. Kiernan Stamatios Lerakis Antonio Piga John B. Porter John Malcolm Walker John Wood | 2013 | Circulation2013，，3： | 3 |
| 3 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011，21，4： | 3 |
| 4 | Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells显示文摘免疫球蛋白 E (IgE ) 在过敏气喘起一个关键作用并且是为 monoclonal 抗体的一个临床上验证的目标。治疗学的 anti-IgE 抗体块在 IgE 和 Fc epsilon 之间的相互作用(Fcε) 受体,它消除或最小化,但是做过敏显型不典型地由 B 房间削减 IgE 的进行中的生产。我们产生了有潜力抵销可溶的 IgE 并且通过抗体依赖者消除表示 IgE B 房间的高亲密关系的 anti-IgE 抗体(MEDI4212 ) 调停房间的 cytotoxicity。MEDI4212 变体被产生在 fucosylation 在抗体或改变的 Fc 区域包含变化以便为 Fcγ 提高抗体亲密关系; RIIIa。所有 MEDI4212 变体与比得上的亲密关系跳了到人的 IgE 野类型(WT ) 抗体。每变体被显示禁止在 IgE 和 Fcε 之间的相互作用; RI,它翻译了成 Fcγ 的有势力抑制;调停 RI 的功能回答。重要地,所有变体在表示房间的膜 IgE 的表面同样跳了到 IgE。然而, MEDI4212 变体为 Fcγ 表明了提高的亲密关系;包括在位置 158 点的多态的变体的 RIIIa。在 Fcγ 的改进;导致的 RIIIa 绑定在用两个都设计的房间线和类的基于的试金交换了的房间增加了受动器功能人的 IgE B 房间。通过它 IgE 的优异抑制,我们预计那受动器功能提高了 MEDI4212 也许能抵销可溶的 IgE 的高水平并且在他们区分并且变得 IgE secreting 血浆房间以前,由消除表示 B 房间的 IgE 提供增加的长期的利益。 | Andrew C. Nyborg Anna Zacco Rachel Ettinger M. Jack Borrok Jie Zhu Tom Martini Rob Woods Christine Kiefer Michael A. Bowen E. Suzanne Cohenz Ronald Herbst Herren Wu Steven Coats | 2016 | Cellular & Molecular Immunology2016，13，3： | 3 |
| 5 | Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features显示文摘 | Walter F Stewart Joshua N Liberman Robert S Sandler Michael S Woods Annette Stemhagen Elsbeth Chee Richard B Lipton Christina E Farup | 1999 | The American Journal of Gastroenterology1999，，12： | 2 |
| 6 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 7 | Does Complete Resection of Melanoma Metastatic to Solid Intra-Abdominal Organs Improve Survival?显示文摘 | Thomas F. Wood MD L. Andrew DiFronzo MD D. Michael Rose MD Philip I. Haigh MD FRCSC Stacey L. Stern MS Leslie Wanek DrPH Richard Essner MD FACS Donald L. Morton MD FACS | 2001 | Annals of Surgical Oncology2001，，8： | 2 |
| 8 | The Tryptophan Hydroxylase Inhibitor LX1031 Shows Clinical Benefit in Patients With Nonconstipating Irritable Bowel Syndrome显示文摘 | Philip M. Brown Douglas A. Drossman Alastair J.J. Wood Gary A. Cline Kenny S. Frazier Jessica I. Jackson Johanna Bronner Joel Freiman Brian Zambrowicz Arthur Sands Michael D. Gershon | 2011 | Gastroenterology2011，，2： | 2 |
| 9 | Accelerated restructuring in rural China fueled by ‘increasing vs. decreasing balance’ land-use policy for dealing with hollowed villages显示文摘 | Hualou Long Yurui Li Yansui Liu Michael Woods Jian Zou | 2011 | Land Use Policy2011，，1： | 2 |
| 10 | Frequency of Extrapancreatic Neoplasms in Intraductal Papillary Mucinous Neoplasm of the Pancreas: Implications for Management显示文摘 | Kaye M. Reid-Lombardo Kellie L. Mathis Christina M. Wood William S. Harmsen Michael G. Sarr | 2010 | Annals of Surgery2010，，1： | 2 |
| 11 | A New Classification of Thoracolumbar Injuries: The Importance of Injury Morphology, the Integrity of the Posterior Ligamentous Complex, and Neurologic Status显示文摘 | Alexander R. Vaccaro Ronald A. Lehman R John Hurlbert Paul A. Anderson Mitchel Harris Rune Hedlund James Harrop Marcel Dvorak Kirkham Wood Michael G. Fehlings Charles Fisher Steven C. Zeiller D Greg Anderson Christopher M. Bono Gordon H. Stock Andrew K. B | 2005 | Spine2005，，20： | 1 |
| 12 | Organizational designs and innovation streams 显示文摘 | Michael Tushman Wendy K Smith Robert Chapman Wood George Westerman Charles 0 Reilly | 2010 | Industrial and Corporate Change2010，19，5： | 1 |
| 13 | Outcomes of systemic to pulmonary artery shunts in patients weighing less than 3 kg: Analysis of shunt type, size, and surgical approach显示文摘 | John W. Myers Nancy S. Ghanayem Yumei Cao Pippa Simpson Katie Trapp Michael E. Mitchell James S. Tweddell Ronald K. Woods | 2013 | The Journal of Thoracic and Cardiovascular Surgery2013，，： | 1 |
| 14 | Diversity Programs in Chain Restaurant 显示文摘 | Woods Robert H Sciarini Michael P | 1995 | Cornell Hotel and Restau- rant Administration Quarterly1995，1，36： | 1 |
| 15 | Angular measurements of light scattered by turbid chairal media using linear Stokes polarimeter 显示文摘 | Guo Xinxin Michael F G Wood I A Vitkin | 2006 | J Biomed Opt2006，11，04： | 1 |
| 16 | Deconstructing rural protest: the emergence of a new social movement 显示文摘 | Michael Woods | 2003 | Journal of Rural Studies2003，19，3： | 1 |
| 17 | Driving high voltage piezoelectric actuators in microrobotic applications 显示文摘 | Michael Karpelson Gu-Yeon Wei Robert J Wood | 2012 | Sensors and Actuators2012，，： | 1 |
| 18 | Ovarian 11β-Hydroxysteroid Dehydrogenase (11βHSD) Activity Is Suppressed in Women With Anovulatory Polycystic Ovary Syndrome (PCOS): Apparent Role for Ovarian Androgens显示文摘 | Anthony E. Michael Christine Glenn Peter J. Wood Rachel J. Webb Laura Pellatt Helen D. Mason | 2013 | The Journal of Clinical Endocrinology & Metabolism2013，，8： | 1 |
| 19 | Desensitization of vascular response in vivo: contribution of genetic variation in the α2B-adrenergic receptor subtype显示文摘 | Mordechai Muszkat Daniel Kurnik Gbenga G Sofowora Joseph Solus Hong-Guang Xie Paul A Harris Scott M Williams Alastair JJ Wood C Michael Stein | 2010 | Journal of Hypertension2010，，2： | 1 |
| 20 | Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression显示文摘 | Michael J. Wargovich Arnaldo Jimenez Kathy McKee Vernon E. Steele Marco Velasco Johnnie Woods Roger Price Kenneth Gray | 2000 | Carcinogenesis2000，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员