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| 1 | TT virus infection in patients with chronic hepatitis B and response of TTV to lamivudine显示文摘AIM: To investigate the responses of TT virus (TTV) and hepatitis B virus (HBV) to a long-term lamivudine therapy.METHODS: Sixteen patients infected with both TTV and HBV were treated with lamivudine 100 mg daily for 30 months. Blood samples were drawn at the beginning of the therapy and subsequently at month 3, 6, 9, 12 and 30.Serum TTV was quantified by real time PCR and serum HBV was detected by hybridization assay and nested polymerase chain reaction.RESULTS: TTV infection was detected in 100 % of HBV-infected patients. Loss of serum TTV DNA after one year of treatment occurred in 1/16 (6 %) patients. At the end of therapy, TTV DNA was positive in 94 % of them. The decline of HBV viremia was evident at 3 months after therapy and the response rate was 31%, 44 %, 63 %, 50 % and 50 %at month 3, 6, 9, 12 and 30, respectively.CONCLUSION: TTV replication is not sensitive to lamivudine and is highly prevalent in HBV-infected patients. | Javier Moreno Garcia Rafael Barcena Marugan Gloria Moraleda Garcia M Luisa Mateos Lindeman Jesus Fortun Abete Santos del Campo Terron | 2003 | World Journal of Gastroenterology2003，9，6： | 9 |
| 2 | CXCR4表达可增强弥漫大B细胞淋巴瘤的播散能力并降低患者生存期显示文摘在一些血液系统恶性肿瘤中,趋化因子受体CXCR4与恶性B细胞的迁徙和转移有关。 CXCR4在血液系统肿瘤中过表达已经得到证实,但对弥漫大B细胞淋巴瘤( DLBCL)的作用尚不清楚。为此,作者采用DLBCL细胞系着重对体外细胞迁移和体内播散过程中CXCR4的作用进行研究,并评估94例DLBCL患者活检标本CXCR4表达的预后意义。 | Moreno M J Bosch R Dieguez-Gonzalez R 胡舜 余英豪 | 2015 | 临床与实验病理学杂志2015，31，10： | 3 |
| 3 | Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord显示文摘The aim of this work was to study effects of ketotifen fumarate(KF)on prevention of tissue damage in testes of rats with experimental autoimmune orchitis(EAO)and on the contralateral testis in a model of prolonged testicular cord torsion(TCT).Rats with EAO or TCT were injected intraperitoneally once daily with KF or saline solution(vehicle group).Incidence and severity of testicular damage were evaluated by histopathology using an EAO score or a Johnsen score.Mast cells(MC)were identified by histochemistry and quantified.In EAO model,KF significantly reduced severity of histopathological testicular damage compared to rats in the vehicle group.KF also reduced the number of testicular MC compared to vehicle group.Similarly,in TCT model,multifocal damage of the contralateral testis was observed 30 days after testicular torsion characterized by sloughing of the germinal epithelium,seminiferous tubule atrophy,and interstitial edema.Focal signs of inflammation and fibrosis of seminiferous tubular walls were also observed.In contrast,sections of contralateral testis of rats injected with KF and killed 30 days after surgery showed normal histological features.A significant decrease in the number of MC was observed in rats treated with KF compared to untreated animals.In conclusion,we demonstrated that treatment with KF reduced testicular inflammatory process and MC infiltrates in both EAO and TCT models.The results suggest a promising treatment for infertile male patients with testicular pathologies associated with inflammation and germ cell loss. | Diego Moreno Cristian M Sobarzo Livia Lustig Marcelo G Rodriguez Pena Vanesa Anabella Guazzone | 2020 | Asian Journal of Andrology2020，22，1： | 3 |
| 4 | CXCR4表达促进弥漫大B细胞淋巴瘤播散并降低患者生存显示文摘Moreno M J, Bosch R, Dieguez-Gonzalez R, et al. CXCRg ex- pression enhances diffuse large B cell lymphoma dissemination and decreases patient survival. J Pathol, 2015,235 (3) :445 - 55.在一些血液系统恶性肿瘤中,趋化因子受体CXCR4涉及恶性B细胞的迁移和播散。尽管研究发现CXCR4在血液系统肿瘤过表达,但该受体在弥漫大B细胞淋巴瘤(DL—BCL)中的作用仍未可知。CXCR4在多种肿瘤中是预后不良的标记,与肿瘤转移及患者生存降低相关。 | Moreno M J Bosch R Dieguez-Gonzalez R 魏建国 许春伟 邰艳红 | 2015 | 临床与实验病理学杂志2015，31，8： | 3 |
| 5 | The role of transthoracic echocardiography in the diagnosis and management of acute type A aortic syndrome显示文摘 | Moreno Cecconi Fabio Chirillo Carlo Costantini Gianfranco Iacobone Ercole Lopez Raffaele Zanoli Alberto Gili Stefano Moretti Marcello Manfrin Christopher Münch Lucia Torracca Gian Piero Perna | 2012 | American Heart Journal2012，，1： | 2 |
| 6 | Predicted Effects of Treatment for HCV Infection Vary Among European Countries显示文摘 | Sylvie Deuffic–Burban Pierre Deltenre Maria Buti Tommaso Stroffolini Julie Parkes Nikolai Mühlberger Uwe Siebert Christophe Moreno Angelos Hatzakis William Rosenberg Stefan Zeuzem Philippe Mathurin | 2012 | Gastroenterology2012，，4： | 2 |
| 7 | Avian Escherichia coli virulence factors associated with coli septicemia in broiler chickens显示文摘 | Ramirez Santoyo R M Moreno Sala A Almanza Marquez Y | 2001 | Rev Argent Mecrobiol2001，33，1： | 2 |
| 8 | Impact of Capsule Endoscopy Findings in the Management of Crohn’s Disease显示文摘 | Vicente Lorenzo-Zú?iga Vicente Moreno Vega Eugeni Domènech Eduard Cabré Míriam Ma?osa Jaume Boix | 2010 | Digestive Diseases and Sciences2010，，2： | 2 |
| 9 | E6 molecular variants of human papillomavirus (HPV) type 16: An updated and unified criterion for clustering and nomenclature显示文摘 | Antonio Huertas-Salgado Diana C. Martín-Gámez Pablo Moreno Raúl Murillo María Mercedes Bravo Luisa Villa Mónica Molano | 2010 | Virology2010，，： | 2 |
| 10 | Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers显示文摘瞄准:分析在肝的 anti-HBs 的存在是否移植接受者在阻止 HBV 感染是有效的。方法:23 个病人收到 anti-HBc 积极的肝被学习。九个接受者是由于以前的 HBV 感染积极的 anti-HBc。他们,一个人也收到了在肝前移植时期期间疫苗的 HBV。十四个接受者是由于在预先移植经期期间管理的 HBV 疫苗积极的 anti-HBs。肝活体检视在 10/14 anti-HBc negative/anti-HBs 被获得积极接受者并且在 4/9 anti-HBc 积极接受者。结果:在 46 个月的一个吝啬的后续时期以后,有保护的浆液 anti-HBs 层次的 1 个接受者作为有免疫力的逃跑 HBV 异种的后果得了 de novo HBV 感染。在 14 之中种牛痘的 anti-HBc negative/anti-HBs 积极接受者,有可得到的肝活体检视(10%) 的 1/10 病人在 13 瞬间有肝 HBV-DNA 没有浆液的肝以后的移植病毒的标记并且没得 de novo HBV 感染。种牛痘的 anti-HBc 没有 HBV 疫苗的反应的积极接受者是在浆液和肝积极的 HBV-DNA,病毒的 DNA 在下列测试是连续地否定的,自发的 seroconversion 因此被诊断。结论:由于 HBV 疫苗或过去的 HBV 感染的 anti-HBs 的存在似乎在保护从 anti-HBc 收到肝的病人有效积极施主。然而,有免疫力的逃跑 HBV 异种的出现,能躲避 anti-HBs 保护,应该被看作 HBV 感染的风险。 | Rafael Barcena Gloria Moraleda Javier Moreno M Dolores Martín Emilio de Vicente Jesús Nuo M Luisa Mateos Santos del Campo | 2006 | World Journal of Gastroenterology2006，12，13： | 2 |
| 11 | Inter-simple sequence repeats PCR for characterization of closely related grapevine germplasm 显示文摘 | Moreno S Martin J P Ortiz M | 1998 | Euphytica1998，101，： | 1 |
| 12 | Mechanism of reduced susceptibility to amoxicillin -clavulanic acid in Escherichia coli strains from the health region of Tortosa ( Catalonia, Spain) 显示文摘 | Perez M O Perez -Moreno M Carulla M | 2004 | Clin Microbiol Infect2004，10，： | 1 |
| 13 | Expression profiles of Dax1,Dmrt1,and Sox9 during temperature sex determination in gonads of the sea turtle Lepidochelys olivacea显示文摘 | Landa P A Moreno M N | 2002 | Genaral & Comparative Endocrinology2002，129，1： | 1 |
| 14 | Acute toxicity of LAS homologues in marine microalgae : esterase activity and inhibition growth as endpoints of toxicity 显示文摘 | HAMPEL M MORENO G I SOBRINO C | 2001 | Ecotoxicol Environ Safety2001，48，： | 1 |
| 15 | The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability显示文摘 | Conrad M Moreno SG Sinowatz F | 2005 | Mol Cell Biol2005，25，17： | 1 |
| 16 | On the characterization of acidic and basic surface sites on carbons by various techniques显示文摘 | M V Lopez - ramon F Stoeckli C Moreno - castilla F C | 1999 | Carbon1999，37，： | 1 |
| 17 | Expression and regulation of scavenger receptor class B type I ( SR - BI) in gall bladder epithelium 显示文摘 | MIQUEL JF MORENO M AMIGO L | 2003 | Gut2003，52，7： | 1 |
| 18 | Diaphragmmatil hernia after transshiatal esophagectomy 显示文摘 | Tapia DJ Sanchez R Moreno M | 2000 | Rec Esp Anestesiol Reamin2000，7，2： | 1 |
| 19 | Snaking2, an antimicrobiaI peptide from potato whose gene is locally in- duced by wounding and responds to pathogen infection 显示文摘 | Bcrrocal-Lobo M Segura A Moreno M | 2002 | Plant Physiology2002，128，3： | 1 |
| 20 | in vitro glycation and antigenicity of soy proteins显示文摘 | van de LAGMAT J SILVAN J M MORENO J | 2007 | Food Research International2007，40，1： | 1 |
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