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| 1 | Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is the fifth most com-mon cancer and the second cause of cancer-related death worldwide. The incidence of HCC is constantly increasing in correlation with the rise in diabetes and obesity, arguing for an urgent need for new developments in the treatment of this lethal cancer. Exosomes are small double-membrane vesicles loaded with distinct cargos, particularly small non-coding RNAs called microRNAs, representative of each donor cell and secreted to affect the features of neighboring cells or recipient cells located further away, like in the case of metastasis. A better understanding of the role of exosomes with a microRNA signature in cancer pathogenesis gave rise to the concept of their use as a noninvasive diagnostic biomarker and in the treatment of cancer, including HCC. In this communication, we review recent works that demonstrate that hepatic stellate cells establish an epigenetic communication with liver cancer cells, which affects their pro-malignant features. If naturally secreted patient-derived exosomes show major limitations concerning their clinical use, bio-engineered exosome mimetics that incorporate controlled components and exhibit no protumoral properties could be promising carriers for the treatment of liver cancers, which is the organ preferentially targeted by systemic injection of exosomes. | Angélique Gougelet | 2018 | World Journal of Hepatology2018，10，11： | 6 |
| 2 | Expression of Tissue Factor in High-Grade Carotid Artery Stenosis: Association With Plaque Destabilization显示文摘 | Sebastian Jander Matthias Sitzer Angélique Wendt Michael Schroeter Martin Buchkremer Mario Siebler Wolfram Müller Wilhelm Sandmann Guido Stoll | 2001 | Stroke: Journal of the American Heart Association2001，，4： | 3 |
| 3 | Estimate of Hydrofluorocarbon Emissions for 2012–16 in the Yangtze River Delta, China显示文摘Hydrofluorocarbons(HFCs)have been widely used in China as substitutes for ozone-depleting substances,the production and use of which are being phased out under the Montreal Protocol.China is a major consumer of HFCs around the world,with its HFC emissions in CO2-equivalent contributing to about 18%of the global emissions for the period2012-16.Three methods are widely used to estimate the emissions of HFCs-namely,the bottom-up method,top-down method and tracer ratio method.In this study,the tracer ratio method was adopted to estimate HFC emissions in the Yangtze River Delta(YRD),using CO as a tracer.The YRD region might make a significant contribution to Chinese totals owing to its rapid economic growth.Weekly flask measurements for ten HFCs(HFC-23,HFC-32,HFC-125,HFC-134 a,HFC-143 a,HFC-152 a,HFC-227 ea,HFC-236 fa,HFC-245 fa and HFC-365 mfc)were conducted at Lin’an Regional Background Station in the YRD over the period 2012-16,and the HFC emissions were 2.4±1.4 Gg yr-1 for HFC-23,2.8±1.2 Gg yr-1 for HFC-32,2.2±1.2 Gg yr-1 for HFC-125,4.8±4.8 Gg yr-1 for HFC-134 a,0.9±0.6 Gg yr-1 for HFC-152 a,0.3±0.3 Gg yr-1 for HFC-227 ea and 0.3±0.2 Gg yr-1 for HFC-245 fa.The YRD total HFC emissions reached 53 Gg CO2-e yr-1,contributing 34%of the national total.The per capita HFC CO2-equivalent emissions rate was 240 kg yr-1,while the values of per unit area emissions and per million GDP emissions reached 150 Mg km-2yr-1 and 3500 kg yr-1(million CNY GDP)-1,which were much higher than national or global levels. | Jingjiao PU Honghui XU Bo YAO Yan YU Yujun JIANG Qianli MA Liqu CHEN | 2020 | Advances in Atmospheric Sciences2020，37，6： | 2 |
| 4 | MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation显示文摘A recent work of Iliopoulos et al published in Cell highlighted a circuit orchestrated by microRNAs (miRNAs) that results in liver tumorigenesis and inflammation. This feedback loop, governed by miR-24 and miR-629, promotes a hepatocyte nuclear factor-4α transient inhibition resulting in miR-124 induction and signal transducer and activator of transcription 3 activation. These promising data support the use of miRNA mimics or inhibitors as potent therapeutic approaches in liver cancer. | Angélique Gougelet Sabine Colnot | 2013 | World Journal of Gastroenterology2013，19，4： | 2 |
| 5 | Modulation of the cutoff wavelength in the spectra for solar selective absorbing coating based on high-entropy films显示文摘This paper demonstrates an intrinsic modulation of the cutoff wavelength in the spectra for solar selective absorbing coating based on high-entropy films.The(NiCuCrFeSi)N((NCCFS)N)films were deposited by a magnetron sputtering system.Rutherford backscattering spectroscopy analysis confirms the uniform composition and good homogeneity of these high-entropy films.The real and imaginary parts of the permittivity for the(NCCFS)N material are calculated on the basis of the reflectance spectral fitting results.A redshift cutoff wavelength of the reflectance spectrum with increasing nitrogen gas flow rate exists because of the different levels of dispersion when changing nitrogen content.To realize significant solar absorption,the film surface was reconstituted to match its impedance with air by designing a pyramid nanostructure metasurface.Compared with the absorptance of the as-deposited films,the designed metasurface obtains a significant improvement in solar absorption with the absorptance increasing from 0.74 to 0.99.The metasurfaces also show low mid-infrared emissions with thermal emittance that can be as low as 0.06.These results demonstrate a new idea in the design of solar selective absorbing surface with controllable absorptance and low infrared emission for high-efficiency photo-thermal conversion. | Ping Song Cong Wang Jie Ren Ying Sun Yong Zhang Angélique Bousquet Thierry Sauvage Eric Tomasella | 2020 | International Journal of Minerals,Metallurgy and Materials2020，27，10： | 2 |
| 6 | Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model显示文摘 | Yoanne Mousseau Séverine Mollard Karine Faucher-Durand Laurence Richard Angélique Nizou Jeanne Cook-Moreau Yasser Baaj Hao Qiu Xavier Plainard Laurent Fourcade Benoit Funalot Franck G. Sturtz | 2012 | Breast Cancer Research and Treatment2012，，1： | 1 |
| 7 | MIWI2 Is Essential for Spermatogenesis and Repression of Transposons in the Mouse Male Germline显示文摘 | Michelle A. Carmell Angélique Girard Henk J.G. van de Kant Deborah Bourc’his Timothy H. Bestor Dirk G. de Rooij Gregory J. Hannon | 2007 | Developmental Cell2007，，4： | 1 |
| 8 | Deeper in the human cornea proteome using nanoLC–Orbitrap MS/MS: An improvement for future studies on cornea homeostasis and pathophysiology显示文摘 | Stéphane D. Galiacy Carine Froment Emmanuelle Mouton-Barbosa Angélique Erraud Karima Chaoui Laurence Desjardins Bernard Monsarrat Fran?ois Malecaze Odile Burlet-Schiltz | 2011 | Journal of Proteomics2011，，1： | 1 |
| 9 | Perineal retraining improves conservative treatment for faecal incontinence: A multicentre randomized study显示文摘 | Henri Damon Laurent Siproudhis Jean-Luc Faucheron Thierry Piche Laurent Abramowitz Marianne Eléouet Isabelle Etienney Philippe Godeberge Guy Valancogne Angélique Denis Fran?ois Mion Anne-Marie Schott | 2013 | Digestive and Liver Disease2013，，： | 1 |
| 10 | Expression of Tissue Factor in High-Grade Carotid Artery Stenosis: Association With Plaque Destabilization显示文摘 | Sebastian Jander Matthias Sitzer Angélique Wendt Michael Schroeter Martin Buchkremer Mario Siebler Wolfram Müller Wilhelm Sandmann Guido Stoll | 2001 | Stroke: Journal of the American Heart Association2001，，4： | 1 |
| 11 | CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling显示文摘 | Angélique Levoye Karl Balabanian | 2009 | Blood2009，113，： | 1 |
| 12 | Bru 1 gene and potential alternative sources of resistance to sugarcane brown rust disease显示文摘 | Josefina Racedo María F. Perera Romina Bertani Claudia Funes Victoria González María I. Cuenya Angélique D′Hont Bj?rn Welin Atilio P. Castagnaro | 2013 | Euphytica2013，，3： | 1 |
| 13 | Utilization of a major brown rust resistance gene in sugarcane breeding显示文摘 | Neil C. Glynn Chris Laborde R. Wayne Davidson Mike S. Irey Barry Glaz Angélique D’Hont Jack C. Comstock | 2013 | Molecular Breeding2013，，2： | 1 |
| 14 | An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands显示文摘 | A. Dick Vethaak Joost Lahr S. Marca Schrap Angélique C. Belfroid Gerard B.J. Rijs Anton Gerritsen Jacob de Boer Astrid S. Bulder Guy C.M. Grinwis Raoul V. Kuiper Juliette Legler Tinka A.J. Murk Willie Peijnenburg Henk J.M. Verhaar Pim de Voogt | 2005 | Chemosphere2005，，4： | 1 |
| 15 | Diploid/Polyploid Syntenic Shuttle Mapping and Haplotype-Specific Chromosome Walking Toward a Rust Resistance Gene (Bru1) in Highly Polyploid Sugarcane (2n ~ 12x ~ 115)显示文摘 | Le Cunff Lo?c Garsmeur Olivier Raboin Louis Marie Pauquet Jérome Telismart Hugues Selvi Athiappan Grivet Laurent Philippe Romain Begum Dilara Deu Monique Costet Laurent Wing Rod Glaszmann Jean Christophe D’Hont Angélique | 2008 | Genetics2008，，1： | 1 |
| 16 | Induction of Transglutaminase 2 by a Liver X Receptor/Retinoic Acid Receptor α Pathway Increases the Clearance of Apoptotic Cells by Human Macrophages显示文摘 | Cédric Rébé Magalie Raveneau Angélique Chevriaux Daniela Lakomy Anne-Laure Sberna Annie Costa Ginette Bessède Anne Athias Eric Steinmetz Jean Marc A. Lobaccaro Georges Alves Alexandre Menicacci Sébastien Vachenc Eric Solary Philippe Gambert David Masson | 2009 | Circulation Research2009，，4： | 1 |
| 17 | mTORC1 Targets the Translational Repressor 4E-BP2, but Not S6 Kinase 1/2, to Regulate Neural Stem Cell Self-Renewal In Vivo显示文摘 | Nathaniel W. Hartman Tiffany V. Lin Longbo Zhang Grace E. Paquelet David M. Feliciano Angélique Bordey | 2013 | Cell Reports2013，，： | 1 |
| 18 | Expression of Tissue Factor in High-Grade Carotid Artery Stenosis: Association With Plaque Destabilization显示文摘 | Sebastian Jander Matthias Sitzer Angélique Wendt Michael Schroeter Martin Buchkremer Mario Siebler Wolfram Müller Wilhelm Sandmann Guido Stoll | 2001 | Stroke: Journal of the American Heart Association2001，，4： | 1 |
| 19 | A new ab initio potential energy surface for the Ne-H2 interaction显示文摘 | Lique F | 2009 | Chem Phys Lett2009，471，： | 1 |
| 20 | Fat globule membrane composition on water holding capacity and water mobility in casein rennet gel: A nuclear mag- netic resonance self-diffusion and relaxation study 显示文摘 | ANGI~LIQUE M MIREILLE C ALAIN R | 2006 | International Dairy Journal2006，16，4： | 1 |
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