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| 1 | Gut bless you:The microbiota-gut-brain axis in irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS)is a common clinical label for medically unexplained gastrointestinal symptoms,recently described as a disturbance of the microbiota-gut-brain axis.Despite decades of research,the pathophysiology of this highly heterogeneous disorder remains elusive.However,a dramatic change in the understanding of the underlying pathophysiological mechanisms surfaced when the importance of gut microbiota protruded the scientific picture.Are we getting any closer to understanding IBS’etiology,or are we drowning in unspecific,conflicting data because we possess limited tools to unravel the cluster of secrets our gut microbiota is concealing?In this comprehensive review we are discussing some of the major important features of IBS and their interaction with gut microbiota,clinical microbiota-altering treatment such as the low FODMAP diet and fecal microbiota transplantation,neuroimaging and methods in microbiota analyses,and current and future challenges with big data analysis in IBS. | Eline Margrete Randulff Hillestad Aina van der Meeren Bharat Halandur Nagaraja Ben RenéBjørsvik Noman Haleem Alfonso Benitez-Paez Yolanda Sanz Trygve Hausken Gülen Arslan Lied Arvid Lundervold Birgitte Berentsen | 2022 | World Journal of Gastroenterology2022，28，4： | 15 |
| 2 | Sonography of the small intestine显示文摘In the last two decades, there has been substantial development in the diagnostic possibilities for examining the small intestine. Compared with computerized tomography, magnetic resonance imaging, capsule endoscopy and double-balloon endoscopy, ultrasonography has the advantage of being cheap, portable, flexible and user-and patient-friendly, while at the same time providing the clinician with image data of high temporal and spatial resolution. The method has limitations with penetration in obesity and with intestinal air impairing image quality. The flexibility ultrasonography offers the examiner also implies that a systematic approach during scanning is needed. This paper reviews the basic scanning techniques and new modalities such as contrast-enhanced ultrasound, elastography, strain rate imaging, hydrosonography, allergosonography, endoscopic sonography and nutritional imaging, and the literature on disease-specific findings in the small intestine. Some of these methods have shown clinical benefit, while others are under research and development to establish their role in the diagnostic repertoire. However, along with improved overall image quality of new ultrasound scanners, these methodshave enabled more anatomical and physiological changes in the small intestine to be observed. Accordingly, ultrasound of the small intestine is an attractive clinical tool to study patients with a range of diseases. | Kim Nylund Svein Фdegaard Trygve Hausken Geir Folvik Gülen Arslan Lied Ivan Viola Helwig Hauser Odd-Helge Gilja | 2009 | World Journal of Gastroenterology2009，15，11： | 9 |
| 3 | Strategies of heavy metal uptake by three plant species growing near a metal smelter显示文摘 | H Dahmani-Muller F van Oort B Gélie M Balabane | 2000 | Environmental Pollution2000，，2： | 2 |
| 4 | The Adult Substantia Nigra Contains Progenitor Cells with Neurogenic Potential 显示文摘 | Lie DC Dziewczapolski G Willhoite AR | 2002 | J Neurosci2002，22，： | 1 |
| 5 | In vitro uptake and interaction between arginine and lysine in the intestine of Atlantic salmon ( Salmo salar) 显示文摘 | BERGE G E BAKKE-MCKELLEP A M LIED E | 1999 | Aquaculture1999，179，14： | 1 |
| 6 | A feature-based classification technique for blindimage steganalysis显示文摘 | Lie W N Lin G S | 2005 | IEEE Transactions on Multimedia2005，7，6： | 1 |
| 7 | Expression of p27,p21and p16 protein in early squamous cervical cancer and its relation to prognosis显示文摘 | Van de Putte G Holm R Lie AK | 2003 | Gynecol Oncol2003，89，1： | 1 |
| 8 | Pharmaco-kinetics of deferiprone in patients with 茁-thalassaemia显示文摘 | LIE M G L TOTSAPOL J PIYADA J | 2011 | Clin Phamracokinet2011，50，1： | 1 |
| 9 | A feature-based Classification Technique for Blind Image Steganalysis显示文摘 | Lie W N Lin G S | 2005 | IEEE Transactions on Multimedia2005，7，6： | 1 |
| 10 | High wear rates and extensive osteolysis in 3 types of uncemented total hip arthroplasty:a review of the PCA,the Harris Galante and the Profile/Tri-Lock Plus arthroplasties with a minimum of 12 years median follow-up in 96 hips显示文摘 | Hallan G Lie SA Havelin LI | | 0，，04： | 1 |
| 11 | Coexpression of PMP22 gene with MBP and P0 during de novo myelination and nerve repair显示文摘 | Kuhn G Lie A Wilms S | | 0，，： | 1 |
| 12 | On fatigue damage accumulation from in-line and cross-flow vortex-induced vibration on riser显示文摘 | Baarholm G S Larsen C M Lie H | 2006 | Journal of Fluids and Structures2006，22，： | 1 |
| 13 | Quantificatian of PoIyma BK Vimria in hemorrhagic cystitis complieaing bone marrow transplantation显示文摘 | Leun g A Y Suan CK Lie A K | 2001 | Blood2001，98，6： | 1 |
| 14 | UGT1A6genotype-related pharmacokinetics of deferiprone ( L1) inhealthy volunteers显示文摘 | LIE M G L TOTSAPOL J JEERANUT T | 2008 | Br J Clin Pharmacol2008，65，6： | 1 |
| 15 | Clinicopathological featur--es and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantationJ bone显示文摘 | Leun g A Y Mak R Lie AK | 2002 | Marrow Transplant2002，29，6： | 1 |
| 16 | Gastrointestinal food hypersensitiyity: symptoms, di- agnosis and provocation tests显示文摘 | Arslan Lied G | 2007 | Turk J Gastroenterol2007，18，1： | 1 |
| 17 | VSC transmission system using flyingcapacitor multilevel converters and hybrid PWM control显示文摘 | LIE X VASSILIOS G A | 2007 | IEEE Transactions on Power Delivery2007，22，1： | 1 |
| 18 | Dietary carbohydrateutilization in cod ( Gadus morhua ) : metabolicresponses to feeding and fasting显示文摘 | Hemre G I Lie 0 Sundby A | 1993 | Fish Physiologyand Biochemistry1993，10，6： | 1 |
| 19 | 257 ankle arthroplasties performed in Norway between 1994 and 2005显示文摘 | Bj?rg-Tilde S Fevang Stein A Lie Leif I Havelin Johan G Brun Arne Skredderstuen Ove Furnes | 2007 | Acta Orthopaedica2007，，5： | 1 |
| 20 | On fa- tigue damage accumulation from in-line and cross flow vortex-induced vibrations on risers显示文摘 | BAARHOLM G S LARSEN C M LIE H | 2006 | J Fluids and Structures2006，22，1： | 1 |
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