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| 1 | Systematic analysis of the safety and benefits of transvaginal hybrid-NOTES cholecystectomy显示文摘AIM: To evaluate transvaginal hybrid-NOTES cholecystectomy(TVC) during its clinical establishment and compare it with the traditional laparoscopic technique(LC).METHODS: The specific problems and benefits of TVC were reviewed using a registry analysis,a comparative cohort study and a randomized clinical trial. At first,feasibility,safety and specific complications of the TVC were analyzed based on the first 488 data sets of the German NOTES Registry(GNR). Hereafter,we compared the early postoperative results of our first 50 TVC-patients with those of 50 female LCpatients matched by age,BMI and ASA classification. The same cohort was contacted an average of two years later to evaluate long-term results concerning pain and satisfaction with the aesthetic results and the overall postoperative results as well as sexual intercourse by means of two domains of the German version of the Female Sexual Function Index(FSFI-d). Consequently,we performed a randomized clinical trial comparing 20 TVC-patients with 20 needlescopic/3-trocar cholecystectomies(NC) also concerning the early postoperative results as well as pain,satisfaction and quality of life by means of the Eypasch Gastrointestinal Quality of Life Index(GIQLI) in the later course. Finally,we discussed the results in accordance with other published studies.RESULTS: The complication(3.5%) and conversion rates(4.1%) for TVC were low in the GNR and comparable to those of the LC. Access related intraoperative complications included injuries to the bladder(n = 4; 0.8%) and bowel(n = 3; 0.6%). The study cohort revealed less postoperative pain after TVC comparing to the LC-patients on the day of surgery(NRS,1.5/10 vs 3.1/10,P = 0.003),in the morning(NRS,1.9/10 vs 2.8/10,P = 0.047) and in the evening(NRS,1.1/10 vs 1.8/10,P = 0.025) of postoperative day(POD) one. The randomized clinical trial consistently found less cumulative pain until POD 2(NRS,8/40 vs 14/40,P = 0.043),as well as until POD 10(NRS,22/190 vs 41/190,P = 0.010). Furthermore,the TVC-patients had a better quality of life on POD 10 than did the LC-patients(GIQLI,124/144 vs 107/144,P = 0.028). The complication rates were comparable and no specific problems were detected in the long-term follow-up for sexual intercourse for either group. The TVC-patients were more satisfied with the aesthetic result in the long-term course in the matched cohort analysis(1.00 vs 1.88,P < 0.001) as well as in the randomized clinical trial(1.00 vs 1.70,P < 0.001) when compared with the LC-patients.CONCLUSION: TVC is a feasible procedure with a high safety profile and has advantages in regard to postoperative pain and aesthetic results when compared with LC or NC. | Dirk R Bulian Jurgen Knuth Kai S Lehmann Axel Sauerwald Markus M Heiss | 2015 | World Journal of Gastroenterology2015,21,38: | 3 |
| 2 | Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury显示文摘 | Caudrillier Axelle Kessenbrock Kai Gilliss Brian M Nguyen John X Marques Marisa B Monestier Marc Toy Pearl Werb Zena Looney Mark R | 2012 | EN2012,,7: | 2 |
| 3 | Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct 显示文摘 | Necula M Kayed R Milton S | 2007 | J Biol Chem2007,282,10: | 1 |
| 4 | Source and tectonic implications of tonalite-trondhjemite magmatism in the Klarnath Mountains 显示文摘 | Barnes C G Petersen S W Kistler R W Murray R Kays M A | 1996 | Contrib Mineral Petrol1996,123,1: | 1 |
| 5 | Periodic waves and their limits for the Camassa-Holm equation显示文摘 | LIU Z R KAYED A M CHEN C | 2006 | International Journal of Bifurcation and Chaos2006,16,8: | 1 |
| 6 | Full-coverage film cooling part 1:Comparison of heat transfer data for three injection angles 显示文摘 | CRAWFORD M E KAYS W M MOFFAT R J | 1980 | ASME Journal of Engineering for Power1980,102,: | 1 |
| 7 | Burst strength analysis of casing withgeometrical imperfections 显示文摘 | Huang Xiaoguang Chen Yanyun Lin Kai Mihsein M Kibble K Hall R | 2007 | Journal of Pressure VesselTechnology?2007,129,4: | 1 |
| 8 | A survey of Web i nforma tion extraction systems显示文摘 | Kayed M Girgis R Shaalan K F | 2006 | IEEE Transactions on Knowl edge and Data Engineering2006,18,10: | 1 |
| 9 | A Survey of Web Information Extraction Systems显示文摘 | Chang M Kayed R Girgis F | 2006 | IEEE Transactions on Knowledge and Data Engineering2006,18,10: | 1 |
| 10 | Cryopreservation of human embryos and its contribution to in vitro fertilization success rates显示文摘 | Kai MW Sebastiaan M Sjoerd R | 2014 | Fertil Steril2014,102,: | 1 |
| 11 | Extracting Ontological Concepts for Tendering Conceptual Structures 显示文摘 | R M Colomb | 2002 | Data and Knowledge Engineering2002,,40: | 1 |
| 12 | Predictor of Asthma Three Years after Hospital Admission for Wheezing in Infancy显示文摘 | Tian M R Annek S Kai K | 2000 | J Pediatr2000,106,6: | 1 |
| 13 | n-Hexane neuropathy caused by addictive inhalation: clinical and electrophysiological features显示文摘 | KUWABARA S KAI M R NAGASE H | 1999 | Eur Neurol1999,41,3: | 1 |
| 14 | Measurement of health-related quality of life in patients with chronic kidneydisease in Japan with EuroQol (EQ-5D) 显示文摘 | Tajima R Kondo M Kai H | 2010 | Clin ExpNephrol2010,14,: | 1 |
| 15 | Oasis effect observed at the Zhangye oasis in Hexi Corridor显示文摘 | Kai K M Matsuda R Sato | 1997 | J Meteor Soc Japan1997,61,75: | 1 |
| 16 | Small molecular inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct显示文摘 | Necula M Kayed R Milton S | 2007 | J Biol Chem2007,282,10: | 1 |
| 17 | Regulation of conidiation and adenylyl cyclase levels by the Get protein GNA-3 in Neurospora erassa显示文摘 | Kays A M Rowley P S Baasiri R A | 2000 | Molecular and Cellular Biology2000,20,: | 1 |
| 18 | Structural and dynamic features of Alzheim-er's Aβpeptide in amyloid fibrils studied by site-directed spin labeling显示文摘 | Tbrbk M Milton S Kayed R | 2002 | J Biol Chem2002,277,40: | 1 |
| 19 | Tracking animal location and activity with an automated radio telemetry system in a tropical rainforest 显示文摘 | KAYS R TILAK S CROFOOT M | 2011 | Computer Journal2011,54,12: | 1 |
| 20 | Feature-subspace aggregating: Ensembles for stable and unstable learners 显示文摘 | KAI M T JONATHAN R W SWEE C T | 2011 | Machine Learning2011,82,3: | 1 |