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| 1 | 东天山觉罗塔格红云滩花岗岩年代学、地球化学及其构造意义显示文摘东天山觉罗塔格地区广泛发育的晚古生代岩浆岩及相关的矿产一直是东天山大地构造研究的焦点。觉罗塔格南缘红云滩花岗质岩体的岩石、矿物组合显示典型的钙碱性火山弧花岗岩特征。岩石地球化学研究表明,该花岗质岩石富集大离子亲石元素而亏损高场强元素,是洋壳俯冲所导致的下地壳物质部分熔融、岩浆分离结晶和上地壳同化混染作用的产物。LAM-ICP/MS锆石定年结果表明,红云滩花岗岩侵位于早-中石炭世(328.5±9.3Ma)。结合觉罗塔格地区由南至北,晚古生代矿产分布由火山沉积-热液改造型铁矿向斑岩型铜钼矿过渡的特征、火山-沉积岩分布和该区晚古生代的大地构造演化历史,作者推测:早古生代觉罗塔格洋向塔里木板块俯冲并形成中天山岛弧之后,该洋盆并未完全消亡,并于晚古生代时极性反转,向北俯冲于准-吐-哈地块之下。红云滩花岗岩正是形成于晚古生代觉罗塔格俯冲洋壳之上的火山弧环境。觉罗塔格地区晚古生代的岩浆岩,火山-沉积岩和矿产分布均不同程度受控于这一大地构造背景。 | 吴昌志 张遵忠 Khin Zaw Fernando Della-Pasque 唐俊华 郑远川 汪传胜 三金柱 | 2006 | 岩石学报2006，22，5： | 93 |
| 2 | 澳大利亚造山型金矿和侵入岩有关金矿系统流体包裹体资料和矿化过程的比较显示文摘We have examined the fluid inclusion data and fluid chemistry of Australian orogenic and intrusion-related gold deposits to determine if similar mineralization processes apply to both styles of deposits.The fluid inclusion data from the Yilgarn craton,the western subprovince of the Lachlan orogen,the Tanami,Tennant Creek and Pine Creek regions,and the Telfer gold mine show that mineralization involved fluids with broadly similar major chemical components(i.e.H_2O+NaCl+CO_2±CH_4±N_2).These deposits formed over a wide range of temperature-pressure conditions(<200 to>500℃,<100~400MPa).Low salinity, CO_2-bearing inclusions and low salinity aqueous inclusions occur in both systems but the main difference between these two types of deposits is that most intrusion-related gold deposits also contain at least one population of high-salinity aqueous brine.Oxygen and hydrogen isotope data for both styles of deposit usually cannot distinguish between a magmatic or metamorphic source for the ore-bearing fluids.However,sulfur and lead isotope data for the intrusion-related gold deposits generally indicate either a magmatic source or mixing between magmatic and sedimentary sources of fluid.The metamorphic geothermal gradients associated with intrusion-related gold deposits are characterized by low pressure,high temperature metamorphism and high crustal geothermal gradients of>30/km.Where amphibole breakdown occurs in a granite source region,the spatially related deposits are more commonly associated with Cu-Au deposits rather than Au-only deposits that are associated with lower temperature granites.The dominant processes thought to cause gold precipitation in both types of deposits are fluid-rock interaction(e.g.desulfidation)or phase separation.Consideration of the physical and chemical properties of the H_2O-NaCl-CO_2 system on the nature of gold precipitation mechanisms at different crustal levels infers different roles of chemical(fluid-rock interaction)versus rheological(phase separation and/or fluid mixing)host-rock controls on gold deposition.This also implies that at the site of deposition,similar precipitation mechanisms operate at similar crustal levels for both orogenic and intrusion-related gold deposits. | Terry P.Memagh E.N.Bastrakov Khin Zaw A.S.Wygmlak L.A.I.Wybom | 2007 | 岩石学报2007，23，1： | 41 |
| 3 | Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers显示文摘Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide,due to late detection and high recurrence rates.Today,these cancers have a heavy socioeconomic burden,for which a full understanding of their pathophysiological features is warranted to search for promising biomarkers and therapeutic targets.Osteopontin (OPN) is overexpressed in most patients with gastric and liver cancers.Over the past decade,emerging evidence has revealed a correlation of OPN level and clinicopathological features and prognosis in gastric and liver cancers,indicating its potential as an independent prognostic indicator in such patients.Functional studies have verified the potential of OPN knockdown as a therapeutic approach in vitro and in vivo .Furthermore,OPN mediates multifaceted roles in the interaction between cancer cells and the tumor microenvironment,in which many details need further exploration.OPN signaling results in various functions,including prevention of apoptosis,modulation of angiogenesis,malfunction of tumor-associated macrophages,degradation of extracellular matrix,activation of phosphoinositide 3-kinase-Akt and nuclear factor-κB pathways,which lead to tumor formation and progression,particularly in gastric and liver cancers.This editorial aims to review recent findings on alteration in OPN expression and its clinicopathological associations with tumor progression,its potential as a therapeutic target,and putative mechanisms in gastric and liver cancers.Better understanding of the implications of OPN in tumorigenesis might facilitate development of therapeutic regimens to benefit patients with these deadly malignancies. | Dong-Xing Cao Zhi-Jie Li Xiao-Ou Jiang Yick Liang Lum Ester Khin Nikki P Lee Guo-Hao Wu John M Luk | 2012 | World Journal of Gastroenterology2012，18，30： | 29 |
| 4 | 2019年缅甸草地贪夜蛾发生情况考察报告显示文摘缅甸是我国草地贪夜蛾的重要境外虫源区,为了掌握草地贪夜蛾在缅甸的发生与防控情况,2019年5月19-25日,云南省农业科学院与缅甸农业研究司专家联合对缅甸南部、中部、中北部和东部草地贪夜蛾开展了实地调查。结果表明:缅甸全境均有草地贪夜蛾发生,为害严重,田间多种虫态并存。其中,南部玉米大部分已经收获,虫株率62.50%~97.50%;中部区域种植少量的商品甜玉米,防治到位,虫株率6.00%~7.50%;中北部曼德勒敏建玉米种植面积最大,达8000hm^2,80%的地块已成熟收获,处于吐丝-乳熟期的田块虫株率达100%,受害严重;东部掸邦虫株率59%,虫口密度2.60头/株。玉米是缅甸第二大种植作物,全年玉米种植面积达47万~52万hm^2,其中与我国云南接壤的东部掸邦是主要种植区。到5月前因无有效降雨,全境玉米尚未大面积种植,仅有零星种植,随着雨季的来临,玉米种植面积将全面增加,草地贪夜蛾种群数量也将随之增加。因此,加强与缅甸相关部门合作,密切掌握缅甸玉米种植及草地贪夜蛾的发生与防控情况,对我国草地贪夜蛾的监测预警及防控有重要的参考价值。 | 李向永 尹艳琼 吴阔 Khin Thein Nyunt Khin Nyein Chan 赵雪晴 谌爱东 | 2019 | 植物保护2019，45，4： | 15 |
| 5 | Helicobacter pylori acquisition of metronidazole resistance by natural transformation in vitro显示文摘INTRODUCTIONGenetictransformationisaprocesbywhichaceltakesupnakedDNAfromthesurroundingmediumandincorporatesitintoitsowngenomi... | HUA Jiesong 1, ZHENG Peng Yuan 1, Teo Keng Fong 1, Khin Mar Mar 2 and HO Bow 1 | 1998 | World Journal of Gastroenterology1998，4，5： | 8 |
| 6 | 亚贡叶化学成分的分离与鉴定显示文摘目的:对亚贡叶的化学成分进行研究。方法:采用硅胶、ODS和LH-20等柱色谱以及半制备HPLC对亚贡叶的乙醇提取物进行分离纯化。结果:分离得到4个化合物,经谱学数据鉴定为亚麻酸甲酯[(9Z,12Z,15Z)-methyloctadeca-9,12,15-trienoate,1),邻苯二甲酸二丁酯(dibutylphthalate,2),沼菊素(Enhydrin,3)和Polymatin B(4)。结论:化合物1和2为首次从亚贡叶中分离得到。 | 王晓彤 冉小库 徐煜彬 Khin Khin Win Aung 薛凡亲 窦德强 董锋 | 2016 | 中国现代中药2016，18，9： | 7 |
| 7 | 基于mtCOI基因序列的我国云南省和缅甸、柬埔寨草地贪夜蛾种群遗传多样性分析显示文摘为制定有效的草地贪夜蛾防控措施,分别自缅甸、柬埔寨和我国云南省采集4、2和8个种群共542个草地贪夜蛾样品,基于mtCOI基因序列分析这14个种群的遗传多样性指数、遗传分化系数及基因流。结果表明,缅甸草地贪夜蛾种群的单倍型多样性指数和平均核苷酸差异数分别介于0.273~0.396和4.643~6.727之间,高于我国云南省的草地贪夜蛾种群,分别介于0.047~0.214和0.791~3.636之间;除ZT种群、LS种群和TO种群外,其它11个种群的Fu’s F均为显著正值,表明缅甸、柬埔寨和我国云南省的草地贪夜蛾种群未经历种群扩张事件;在14个种群中,LS种群与其它种群分化较明显,TK种群、MY种群、CP种群、MS种群和KY种群有效迁入个数和有效迁出个数之和较高,分别为699.41、682.50、855.76、684.56和701.31,推测这5个种群在草地贪夜蛾基因交流中起着类似'中转站'的作用。 | 李向永 尹艳琼 KHIN Thein Nyunt KHAY Sathya 刘莹 谌爱东 | 2020 | 植物保护学报2020，47，4： | 5 |
| 8 | Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei(Blyth, 1847) and description of a new species显示文摘Trachypithecus,which currently contains 20 species divided into four groups,is the most speciose and geographically dispersed genus among Asian colobines.Despite several morphological and molecular studies,however,its evolutionary history and phylogeography remain poorly understood.Phayre’s langur(Trachypithecus phayrei) is one of the most widespread members of the genus,but details on its actual distribution and intraspecific taxonomy are limited and controversial.Thus,to elucidate the evolutionary history of Trachypithecus and to clarify the intraspecific taxonomy and distribution of T.phayrei,we sequenced 41 mitochondrial genomes from georeferenced fecal samples and museum specimens,including two holotypes.Phylogenetic analyses revealed a robustly supported phylogeny of Trachypithecus,suggesting that the T.pileatus group branched first,followed by the T.francoisi group,and the T.cristatus and T.obscurus groups most recently.The four species groups diverged from each other 4.5-3.1 million years ago(Ma),while speciation events within these groups occurred much more recently(1.6-0.3 Ma).Within T.phayrei,we found three clades that diverged 1.0-0.9 Ma,indicating the existence of three rather than two taxa.Following the phylogenetic species concept and based on genetic,morphological,and ecological differences,we elevate the T.phayrei subspecies to species level,describe a new species from central Myanmar,and refine the distribution of the three taxa.Overall,our study highlights the importance of museum specimens and provides new insights not only into the evolutionary history of T.phayrei but the entire Trachypithecus genus as well. | Christian Roos Kristofer MHelgen Roberto Portela Miguez Naw May Lay Thant Ngwe Lwin Aung Ko Lin Aung Lin Khin Mar Yi Paing Soe Zin Mar Hein Margaret Nyein Nyein Myint Tanvir Ahmed Dilip Chetry Melina Urh EGrace Veatch Neil Duncan Pepijn Kamminga Marcus AHChua Lu Yao Christian Matauschek Dirk Meyer Zhi-Jin Liu Ming Li Tilo Nadler Peng-Fei Fan Le Khac Quyet Michael Hofreiter Dietmar Zinner Frank Momberg | 2020 | Zoological Research2020，41，6： | 5 |
| 9 | Indicators of fatal outcome in severe Plasmodium falciparum malaria:a study in a tertiary-care hospital in Thailand显示文摘Objective:To illustrate the clinical features and investigate the indicators associated with a fatal outcome in adult patients with severe Plasmodium falciparum malaria admitted to the Hospital for Tropical Diseases,Bangkok,Thailand.Methods:We studied 202 adult malaria patients admitted to the Intensive Care Unit.A total of 43 clinical variables were identified by univariate and logistic regression analyses,to eliminate confounding factors.Results:Regarding the statistical methods,only 6 variables-jaundice,cerebral malaria,metabolic acidosis,body mass index,initial respiratory rate,and white blood cell count-were significant indicators of death, with adjusted odds ratios(95%CI) of 15.2(2.1-32.3).4.3(2.3-12.6),3.3(2.3-5.7),2.4(1.9-3.5),2.2 (1.5-2.6),and 1.7(1.2-3.1),respectively.Conclusions:Our study found that jaundice,cerebral malaria,metabolic acidosis,body mass index,initial respiratory rate and white blood cell count were indicators of fatal outcome in severe Plasmodium falciparum malaria.Further studies on the fatal indicators in severe malaria need to be compared with data from different geographical areas,to construct practical measures to address potentially fatal indicators in different settings. | Noppadon Tangpukdee Khin Myat Wai Sant Muangnoicharoen Shigeyuki Kano Nanthaporn Phophak Janram Tiemprasert Srivicha Krudsood Polrat Wilairatana | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 4 |
| 10 | Dermatofibrosarcoma protuberans: from translocation to targeted therapy显示文摘Dermatofibrosarcoma protuberans(DFSP), the most common dermal sarcoma, is a low-grade, slow growing fibroblastic malignant neoplasm that most frequently affects middle aged adults and is characterized by a high local recurrence rate and a low propensity for metastasis. Wide surgical resection or Mohs micrographic surgery(MMS) are the preferred approaches for localized disease, while radiation therapy is warranted for inoperable disease or for cases with positive margins where re-excision is not possible. DFSP is generally regarded as refractory to conventional chemotherapy. Treatment options for systemic disease were limited until the discovery of a unique translocation, t(17;22)(q22;q13)(COL1A1;PDGFB) found in a majority of cases. In recent years, imatinib, a PDGFβR, ABL and KIT inhibitor, has revolutionized systemic therapy in DFSP. In this review, we summarize the epidemiological, clinical, histological and genetic characteristics of DFSP and update the readers on its current management. | Jonathan Noujaim Khin Thway Cyril Fisher Robin L.Jones | 2015 | Cancer Biology & Medicine2015，12，4： | 4 |
| 11 | The evolution of Epstein-Barr virus detection in nasopharyngeal carcinoma显示文摘The detection of Epstein-Barr virus(EBV)in nasopharyngeal carcinoma(NPC)has evolved over the last40 years,transitioning from simple serological tests of latent viral infection to extremely sensitive measurements of | You Quan Li Ni Sann Khin Melvin L.K.Chua | 2018 | Cancer Biology & Medicine2018，15，1： | 3 |
| 12 | The performance of superhydrophobic and superoleophilic carbon nanotube meshes in water–oil filtration显示文摘 | Chee Huei Lee Nick Johnson Jaroslaw Drelich Yoke Khin Yap | 2010 | Carbon2010，，2： | 2 |
| 13 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 14 | 噪声在医疗环境中的污染与治理措施显示文摘针对噪声在医疗环境中带来的危害,在综合考虑建筑声学中相关标准规范的情况下,从建筑布局、室内吸声降噪、隔声、管理制度等方面提出了相应的的治理措施,目的是要引起人们对医疗声环境的重视,并打造人性化的医疗环境。本文对医院声环境的改善具有实用性参考价值。 | 唐凤台 CHEN Khin Fai | 2019 | 电声技术2019，43，7： | 2 |
| 15 | 缅-中女大学生性健康相关知信行的对比性研究显示文摘目的了解缅甸和中国女大学生性健康相关知识、态度和行为状况,为开展性健康教育和干预措施提供科学依据。方法采用整群抽样方法,选择缅甸247名和中国267名女大学生,进行面对面问卷调查,运用统计软件SPSS 16.0进行统计分析。结果缅、中女生性健康相关知识平均得分分别为6.5和9.5分,认知水平高所占比例均极低。缅甸女生的认知水平以低为主(占88.7%),中国女生的认知水平以中等为主(占67.8%),差异有统计学意义(P<0.001)。两国女生对婚前医学检查的看法比较一致,其他与性相关的态度则差别较大。缅中女生发生婚前性行为情况接近,'未发生过'分别占96.8%和97.0%。手淫方面以'没有过'为主,但两国女生在'有过手淫'和'不清楚'的回答上差异有统计学意义(均为P<0.001)。两国女生均主要在中学阶段接触过性健康知识,来源均以学校教育、书刊杂志和同学朋友为主,两国来源的比例差异有统计学意义(P<0.05)。对于大学开设性健康教育课的时间,缅中女生均以大学一年级为主(分别占59.5%和85.8%)、开课方式均以讲座为主(分别占75.7%和46.8%),差异均无统计学意义(P>0.05)。结论缅中两国女生在性健康相关态度和行为方面有一定的相似性,但缅甸女生的性相关知识水平明显低于中国女生,中国的性健康教育模式值得缅甸借鉴。 | 金丽花 KHIN WIN SHWE 蔡秋玲 李春灵 | 2017 | 应用预防医学2017，23，2： | 2 |
| 16 | Eco-bio-social determinants of dengue vector breeding: a multicountry study in urban and periurban Asia显示文摘 | Arunachalam Natarajan Tana Susilowati Espino Fe Kittayapong Pattamaporn Abeyewickreme Wimal Wai Khin Thet Tyagi Brij Kishore Kroeger Axel Sommerfeld Johannes Petzold Max | 2010 | World Health Organization Bulletin of the World Health Organization2010，，3： | 2 |
| 17 | 西双版纳布龙自然保护区勐宋片区附生维管植物多样性与分布特征(英文)显示文摘利用地面观测和单绳上树法初次对布龙自然保护区勐宋片区开展的附生维管植物调查表明:1)在6个样地77株宿主上(共调查96株乔木,占地约0.2ha),共有1756株、丛个体,隶属14科47属103种;相比世界其他区域,物种丰富度处于旧世界热带水平区间,高于温带,但明显低于新世界热带水平;2)兰科植物为最丰富的类群(60%),其次为蕨类植物(24%),其他类群占16%;3)垂直分布特征研究表明,距地面10~15m的中等高度带为物种最丰富的区间,约有51%的物种;0~5m高度带为个体数量最多的区间,共有约24%个体,揭示了除中等高度带以外的另一个重要附生生境;4)常见的绞杀型榕属植物未见,而半附生植物密脉鹅掌柴(Schefflera elliptica)和多蕊木(Tupidanthus calrlgtratus)数量较多。 | 赵明旭 Geekiyanage Nalaka Harrison Rhett Daniel 许建初 Khin Myo Myo Ridwan Nurdiana Dian Paudel Ekananda | 2015 | 植物分类与资源学报2015，37，3： | 2 |
| 18 | Malaria profiles and challenges in artemisinin resistance containment in Myanmar显示文摘Background:This study examined evolving malaria profiles from January,2010 to December,2014 to evaluate achievements and challenges of implementing measures to prevent and control spread of artemisinin resistance in Myanmar.Methods:Using National Malaria Control Programme(NMCP)data,a cross-sectional descriptive study of 52 townships in artemisinin-resistant containment areas in Myanmar was conducted.Annual program data were analysed,and trends over time are graphically presented.Results:In the 52 study townships populated by 8.7 million inhabitants,malaria incidence showed a decreasing trend from 10.54 per 1000 population in 2010 to 2.53 in 2014,and malaria mortalities also decreased from 1.83 per 100000 population in 2010 to 0.17 in 2014.The proportion of confirmed to total tested malaria cases also decreased from 6 to 1%,while identification of cases improved.All cases from all parasites species,including Plasmodium falciparum,decreased.Coverage of LLIN(long-lasting insecticidal net)/ITN(insecticide-treated mosquito nets)and indoor residual spraying(IRS)was high in targeted areas with at-risk persons,even though the total population was not covered.In addition to passive case detection(PCD),active case detection(ACD)was conducted in hard-to-reach areas and worksites where mobile migrant populations were present.ACD improved in most areas from 2012 to 2014,but continues to need to be strengthened.Conclusions:The findings provide useful data on the malaria situation in artemisinin-resistant initiative areas,which may be useful for the NMCP to meet its elimination goal.These profiles could contribute to better planning,implementation,and evaluation of intervention activities. | Thet Wai Nwe Tin Oo Khin Thet Wai Shuisen Zhou Johan van Griensven Palanivel Chinnakali Safieh Shah Aung Thi | 2017 | Infectious Diseases of Poverty2017，6，1： | 2 |
| 19 | Impact of process conditions and coatings on the dehydration efficiency and cellular structure of apple tissue during osmotic dehydration显示文摘 | KHIN M M ZHOU W PERERA C O | 2007 | Journal of Food Engineering2007，79，： | 1 |
| 20 | The Himalayan Yulong porphyry copper belt; product of large-scale strike-slip faulting in eastern Tibet 显示文摘 | Hou Zengqian Ma Hongwen Khin Zaw | 2003 | Economie Geology2003，98，1： | 1 |
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