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32篇 您的检索式：作者名="Iriya"

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	题名	作者	年代	出处	被引量
1	Protective effect of ascorbic acid in experimental gastric cancer: reduction of oxidative stress显示文摘AIM: Oxidative stress participates in the cell carcinogenesis by inducing DNA mutations. Our aim was to assess whether ascorbic acid, an antioxidant, could have a role in preventing ROS (Reactive Oxygen Species) generation in experimental gastric carcinoma in a rat model.METHODS: Experimental gastric cancer was induced in twelve Wistar male rats (weighting 250-350 g) by profound duodeno-gastric reflux throught split gastrojenunostomy. The rats were allocated to the following groups: Group Ⅰ (n=6)was the control; Group Ⅱ (n=6) which was mantained with daily intake of tape water with Vitamin C (30 mg/Kg). After 6 or 12 months, samples of gastric tumor or non tumor mucosa were taken from the anastomosis of both groups.Oxidative stress was measured by superoxide quantification through lucigenin-amplified chemiluminescence base and by staining with Nitrobluetetrazolium. The histopathologic confirmation of adenocarcinoma was made by eosinhemathoxilin method.RESULTS: The intestinal type of gastric adenocarcinoma was microscopically identified in all animals of group Ⅰwhereas only 3 rats of group Ⅱ showed an adenocarcinoma without macroscopic evidence of them. The cancers were located in the anastomosis in all cases. Basal luminescence from tumor gastric tissue generated 38.4±6.8 count per minute/mg/x106 (mean±SD) and 14.9±4.0 count per minute/mg/×106, respectively, in group Ⅰ and Ⅱ animals (P<0.05). The Nitrobluetetrazolium method showed intense staining in tumor tissues but not in non neoplasic mucosa.CONCLUSION: Experimental gastric tumors seem to produce more reactive oxygen species than non neoplasic gastric tissue. The reduction of oxidative stress and gastric tumor incidence in rats were induced by the intake of ascorbic acid. Therefore, it may have a role in the prevention of gastric carcinoma.	Claudia P.M.S.Oliveira Paulo Kassab Fabio P.Lopasso Heraldo P.Souza Mariano Janiszewski Francisco R.M.Laurindo Kioshi Iriya Antonio A.Laudanna	2003	World Journal of Gastroenterology2003，9，3：	2
2	Ki-67 as a prognostic marker in colorectal cancer but not in gastric cancer显示文摘	Oshima CT Iriya K Forones NM	2005	Neoplasma2005，52，5：	1
3	C-erbB-2oncoproteinin gastric carcinoma:correlation with clinical stage and progno-sis显示文摘	Oshima CT Lanzoni VP Iriya K	2001	Int J Biol Markers2001，16，4：	1
4	C-erbB-2 oncoprotein in gastric carcinoma: correlation with clinical stage and prognosis显示文摘	Oshima CT Lanzoni VP Iriya K	2001	Int J Biol Markers2001，16，4：	1
5	Ki-67 as a prognostic marker in colorectal cancer but not in gastric cancer显示文摘	Oshima C Iriya A Forones NM	2005	Neoplasma2005，52，5：	1
6	Study on the tensile creep for early age concrete显示文摘	IRIYA K NEGI T HATTORI T		Proc JSCE0，620，：	1
7	Causes of death in patients with Systemic lupus erthematosus in Sao Paulo,Brazil:a study of 113 autopsie显示文摘	Iriya SM Capelozzi VC Ca Cich I	2005	Arch inter Med2005，161，：	1
8	Ki - 67 as a prognostic marker in colorectal cancer but not in gastric cancer 显示文摘	Oshima CT Iriya K Forones NM	2005	Neoplasma2005，52，5：	1
9	Ki-67 as a prognostic marker in colorectal cancer but not in gastric cancer显示文摘	Oshima CT Iriya K Forones NM	2005	Neoplasma2005，52，5：	1
10	Laboratory simulations with twin-disc machine on head check显示文摘	TAKIKAWA M IRIYA Y		0，，9：	1
11	Ki-67 as a prognostic marker in colorectal cancer but not in gastric cancer显示文摘	OSHIMA C T IRIYA K FORONES N M	2005	Neoplasma2005，52，5：	1
12	Effects of sex hormones on development of urinary bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine显示文摘	Okajima E Hiramatsu T Iriya K	1975	Urol Res1975，3，2：	1
13	Lugol's dye spray chromoendoscopy establishes early diagnosis of esophageal cancer in patients with primary head and neck cancer显示文摘	Hashimoto CL Iriya K Baba ER	2005	Am J Gastroenterol2005，100，2：	1
14	Lugol's dye spray chromoendoscopy establishes early diagnosis of esophageal cancer in patients with primary head and neck cancer 显示文摘	Hashimoto C L Iriya K Baba E R	2005	Am J Gastroenterol2005，100，2：	1
15	Lugol dye endoscopy for analysis of esophageal mueosa in aehalasia 显示文摘	Yamamuro EM Cecconello I Iriya K	1999	Hepatogastroenterology1999，46，27：	1
16	Causes of death in patients with systemic lupus erythematosus in Sao Paulo, Brazil: a study of 113 autopsies显示文摘	Iriya SM Capelozzi VL Calich I	2001	Arch InternMed2001，161，15：	1
17	Ki67 as a prognostic marker in colorectal cancer but not in gastric cancer显示文摘	Oshima CT Iriya K Forones NM	2005	Neoplasma2005，52，5：	1
18	Dietary habits, ethanol and tobacco consumption as predictive factors in the development of esophageal carcinoma in patients with head and neck neoplasms 显示文摘	Rossini-AR Hashimoto CL Iriya K	2008	Diseases of the Esophagus2008，21，4：	1
19	Origin of adenocarcin- oma in Barrett's esophagus: p53 and Ki67 expression and his- topathologie background 显示文摘	Szachnowicz S Cecconello I Iriya K	2005	Clinics2005，60，2：	1
20	C-erbB-2 oncoprotein in gastric carcinoma:correlation with clinical stage and prognosis 显示文摘	Oshima CT Lanzoni VP Iriya K	2001	Int J Biol Markers2001，16，：	1

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