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| 1 | Hepatocellular carcinoma staging systems: Hong Kong liver cancer vs Barcelona clinic liver cancer in a Western population显示文摘BACKGROUND Despite being the world’s most widely used system for staging and therapeutic guidance in hepatocellular carcinoma(HCC)treatment,the Barcelona clinic liver cancer(BCLC)system has limitations,especially regarding intermediate-grade(BCLC-B)tumors.The recently proposed Hong Kong liver cancer(HKLC)staging system appears useful but requires validation in Western populations.AIM To evaluate the agreement between BCLC and HKLC staging on the management of HCC in a Western population,estimating the overall patient survival.METHODS This was a retrospective study of HCC patients treated at a university hospital in southern Brazil between 2011 and 2016.Demographic,clinical,and laboratory data were collected.HCC staging was carried out according to the HKLC and BCLC systems to assess treatment agreement.Overall survival was estimated based on the treatment proposed in each system.RESULTS A total of 519 HCC patients were assessed.Of these,178(34.3%)were HKLC-I;95(18.3%)HKLC-IIA;47(9.1%)HKLC-IIB;29(5.6%)HKLC-IIIA;30(5.8%)HKLCIIIB;75(14.4%)HKLC-IV;and 65(12.5%)HKLC-V.According to the BCLC,25(4.9%)were BCLC-0;246(47.4%)BCLC-A;107(20.6%)BCLC-B;76(14.6%)BCLCC;and 65(12.5%)BCLC-D.The general agreement between the two systems was 80.0%-BCLC-0 and HKLC-I(100%);BCLC-A and HKLC-I/HKLC-II(96.7%);BCLC-B and HKLC-III(46.7%);BCLC-C and HKLC-IV(98.7%);BCLC-D and HKLC-V(41.5%).When sub-classifying BCLC-A,HKLC-IIB,HKLC-IIIA and HKLC-IIIB stages according to the up-to-7 in/out criterion,13.4,66.0,100 and 36.7%,respectively,of the cases were classified as up-to-7 out.CONCLUSION In a Western population,the general agreement between the two systems was 80.0%,although in BCLC-B cases the agreement was low,suggesting that some individuals could be candidates for the curative treatment recommended by the HKLC.The authors suggest that the BCLC system should be routinely employed,although for BCLC-B cases it should be associated with the HKLC system. | Laura Bainy Rodrigues de Freitas Larisse Longo Deivid Santos Ivana Grivicich Mário Reis Alvares-da-Silva | 2019 | World Journal of Hepatology2019，11，9： | 3 |
| 2 | Detecting moving shadows:Algorithms and evaluation显示文摘 | Prati Andrea Mikic Ivana Trivedi Mohan M | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligence2003，25，7： | 1 |
| 3 | CD4+ CD25+ Foxp3 PD1 - reg- ulatory T ceils in acute and stable relapsing-remitting multiple scle- rosis and their modulation by therapy 显示文摘 | Marina S Ivana M Renato L | 2008 | FASEB J2008，22，10： | 1 |
| 4 | Drosophila nemo is an essential gene involved in the regulation of programmed cell death显示文摘 | Ivana Mirkovic Kristi Charish Sharon M Gorski Kristen McKnight Esther M Verheyen | 2002 | Mechanisms of Development2002，，1： | 1 |
| 5 | Platelet responsiveness to aspirin in patients with hyperlipidemia显示文摘 | IVANA V MICHEAL M | 2003 | BM J2003，326，： | 1 |
| 6 | Self-organized porphyrinic materials显示文摘 | CHARLES M D ALESSANDRO V IVANA R | 2009 | Chem Rev2009，109，5： | 1 |
| 7 | Detection moving shadows: algorithms and evaluation显示文摘 | Andrea Prati Ivana Mikic Mohan M Trivedi | 2003 | IEEE Transac- tion on Pattern Analysis And Machine Intelligence2003，25，7： | 1 |
| 8 | Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function显示文摘 | Christian M Ivana M Bartholomaus I | 2007 | Biochem Biophys Res Commun2007，354，1： | 1 |
| 9 | Modulation of poly(ADP-ribosylation) in apoptotic cells 显示文摘 | Ivana Scovassi A Diederich M | 2004 | BiochemPharmacol2004，68，6： | 1 |
| 10 | Influence of the emission trading scheme on generation scheduling显示文摘 | Ivana K Conejo A J James R M | 2009 | Inter- national Journal of Electrical Power and Energy Systems2009，31，9： | 1 |
| 11 | N-acetylcysteine and contrast- induced nephropathy in primary angioplasty显示文摘 | Giancarlo M Emilio A Ivana M | 2006 | N Engl J Med2006，354，29： | 1 |
| 12 | Detecting moving shadows:Algorithms and evaluation 显示文摘 | Prati Andrea Mikic Ivana Trivedi Mohan M | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligeace2003，25，7： | 1 |
| 13 | pH Optical sensors based on sol-gels: Chemical doping versus covalent immobilization显示文摘 | Aleksandra L Ines O Ivana M | 1998 | Analytica1998，367，13： | 1 |
| 14 | A review of concentrating solar power plants in the world and their potential use in Serbia显示文摘 | Tomislav M Pavlovic Ivana S Radonjic Dragana D Milosavl- jevic | 2012 | Renewable and Sus- tainable Energy Reviews2012，16，6： | 1 |
| 15 | Investigation of Tungsten Carbide Supported Pd or Pt as AnodeCatalysts for PEM Fuel Cells 显示文摘 | Nikolic Vladimir M Zugic Dragana L Perovic Ivana M | 2013 | International Journal of Hydro-gen Energy2013，38，11： | 1 |
| 16 | Thermal development of microstructure and precipitation effects in Mg-10%wtGd alloy显示文摘 | JAKUB C IVAN P BOHUMIL A IVANA S RADOMIR K ZDENEK M J VIKTOR C | 2006 | Phys Star A2006，203，： | 1 |
| 17 | Hypertension induces brainβ-Amyloid accumulation,cognitive impairment,and memory deterioration through activation of receptor for advanced glycation end Products in Brain显示文摘 | Daniela C Giada M ivana D | 2012 | Hypertension2012，60，1： | 1 |
| 18 | Chaperone activity of recombinant maize chloroplast protein synthesis elongation factor, EF-Tu Eur显示文摘 | Damodara R Ivana M Satoru K | 2004 | Biochem2004，271，： | 1 |
| 19 | Apical leaking of five rot canal sealers after one year of storage显示文摘 | Ivana M Sonja-Pezelj R Zoran K | 2002 | J Endo2002，28，6： | 1 |
| 20 | The prevention of radiocontrast-agent-induced nephropathy by hemofiltration显示文摘 | Giancarlo Marenzi M D Ivana Marana M D Gianfranco Lauri | 2003 | N Engl J Med2003，349，： | 1 |
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