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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Erythropoietins: a common mechanism of action显示文摘 | Elliott S Pham E Macdougall IC | 2008 | Exp Hematol2008，36，12： | 1 |
| 3 | Role of HERV-W syneytin-1 in placentation and maintenance of human pregnancy 显示文摘 | NOORALI S ROTAR IC LEWIS C | 2009 | Appl Immunohistochem Mol Morphol2009，17，4： | 1 |
| 4 | Steriod-regulated molecular markers of implantation 显示文摘 | Bagchi IC Kumar S | 1999 | Semin Reprod Endocrinol1999，17，3： | 1 |
| 5 | Maintenance therapy with certolizumab pegol for Crohn's disease 显示文摘 | Schreiber S Khaliq-Kareemi M Lawrance IC | 2007 | N Engl J Med2007，357，： | 1 |
| 6 | Omenn syndrome with mutation in RAG1 gene显示文摘 | Jaouad IC Ouldim K Ali Ou Alla S | 2008 | Indian J Pediatr2008，75，9： | 1 |
| 7 | A High Index of Suspicion: The Key to an Early Diagnosis of Wilson’s Disease in Childhood显示文摘 | Icíar Sánchez-Albisua Teresa Garde Loreto Hierro Carmen Camarena Esteban Frauca Angela de la Vega María Carmen Díaz Javier Larrauri Paloma Jara | 1999 | Journal of Pediatric Gastroenterology & Nutrition1999，，2： | 1 |
| 8 | Metaanalysis of regional brain volumes in schizophrenia显示文摘 | WRIGHT IC RABE-HESKETH S WOODRUFF PW | 2000 | Am J Psychiatry2000，157，1： | 1 |
| 9 | Global fibrinolytic capacity is decreased in polycystic ovary syndrome,suggesting a prothrombotic state显示文摘 | Yildiz BO Haznedaroglu IC Kirazli S | 2002 | J Clin Endocrinol Metab2002，87，8： | 1 |
| 10 | Antiinflammatory effects of genistein,a tyrosine kinase inhibitor,on a guinea pig model of asthma显示文摘 | Duan W Kuo IC Selvarajan S | 2003 | American journal of respiratory and critical care medicine2003，167，1： | 1 |
| 11 | Consumer Perceptions of Interact retail service quality 显示文摘 | JNADA S TROCCHIA P Y GWINNER IC | 2002 | International Journalof Service Industry Management2002，13，5： | 1 |
| 12 | Oral clefts,consanguinity,parental tobacco and alcohol use:a case-control study in Rio de Janeiro,Brazil显示文摘 | Leite IC Koifman S | 2009 | Braz Oral Res2009，23，1： | 1 |
| 13 | Bone morphogenetie protein 1 is an extraeellular processing enzyme of the laminin 5 gamma 2 chain显示文摘 | Amano S Scott IC Takahara K | 2000 | J Biol Chem2000，275，22： | 1 |
| 14 | Analytical Models for Conerete Confined with FRP Tubes显示文摘 | BEEQUE J PATNSIK A IC RIZKALLA S H | 2003 | Journal of Composites for Construction2003，7，1： | 1 |
| 15 | Primary phacoemulsification for uncontrolled angle- closure glaucoma显示文摘 | Robert TV Francis IC Lertusumitkul S Kappagoda MB Coro- neo MT | 2000 | J Cataract Refract Surg2000，26，7： | 1 |
| 16 | Developmen t and optimization of mat rix table t for controlled delivery of nicorandih An in vitro study Journal of Molecu larand C ellularCardiology显示文摘 | Agrawal S Deepankar S Dipanka r IC | 2001 | 33(6) :A22001，33，6： | 1 |
| 17 | Primary phacoemulsification for uncontrolled angle-closure glaucoma显示文摘 | Roberts TV Francis IC Lertusumitkul S | | 0，，07： | 1 |
| 18 | Advances in the management of congenital and infantile cataract显示文摘 | Lloyd IC Ashworth J Biswas S Abadi RV | 2007 | Eye2007，21，10： | 1 |
| 19 | Direct writing of copper conductive patterns by ink-iet printing 显示文摘 | PARK B IC KIM D JEONG S | 2007 | Thin Solid Films2007，515，19： | 1 |
| 20 | The transverse myocutaneous gracilis muscle flap:A fast and reliable method for breast reconstruction显示文摘 | Fansa H Schirmer S Wamecke IC | 2008 | Plast Reconstr Surg2008，122，5： | 1 |
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