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| 1 | Orbit determination and time synchronization for a GEO/IGSO satellite navigation constellation with regional tracking network显示文摘Aiming at regional services,the space segment of COMPASS (Phase I) satellite navigation system is a constellation of Geostationary Earth Orbit (GEO),Inclined Geostationary Earth Orbit (IGSO) and Medium Earth Orbit (MEO) satellites.Precise orbit determination (POD) for the satellites is limited by the geographic distribution of regional tracking stations.Independent time synchronization (TS) system is developed to supplement the regional tracking network,and satellite clock errors and orbit data may be obtained by simultaneously processing both tracking data and TS data.Consequently,inconsistency between tracking system and TS system caused by remaining instrumental errors not calibrated may decrease navigation accuracy.On the other hand,POD for the mixed constellation of GEO/IGSO/MEO with the regional tracking network leads to parameter estimations that are highly correlated.Notorious example of correlation is found between GEO's orbital elements and its clock errors.We estimate orbital elements and clock errors for a 3GEO+2IGSO constellation in this study using a multi-satellite precise orbit determination (MPOD) strategy,with which clock error elimination algorithm is applied to separate orbital and clock estimates to improve numerical efficiency.Satellite Laser Ranging (SLR) data are used to evaluate User Ranging Error (URE),which is the orbital error projected on a receiver's line-of-sight direction.Two-way radio-wave time transfer measurements are used to evaluate clock errors.Experimenting with data from the regional tracking network,we conclude that the fitting of code data is better than 1 m in terms of Root-Mean-Square (RMS),and fitting of carrier phase is better than 1 cm.For orbital evaluation,difference between computed receiver-satellite ranging based on estimated orbits and SLR measurements is better than 1 m (RMS).For clock estimates evaluation,2-hour linear-fitting shows that the satellite clock rates are about 1.E-10 s/s,while receiver clock rates are about 1×10 13-1×10 12 s/s.For the 72-hour POD experiment,the average differences between POD satellite clock rates estimates and clock measurements based on TS system are about 1×10 13 s/s,and for receiver clock rates,the differences are about 1×10 15 s/s. | ZHOU ShanShi HU XiaoGong WU Bin LIU Li QU WeiJing GUO Rui HE Feng CAO YueLing Wu XiaoLi ZHU LingFeng SHI Xin TAN HongLi | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,6: | 44 |
| 2 | Management of cytokine release syndrome related to CAR-T cell therapy显示文摘Chimeric antigen receptor T (CAR-T) cell therapy is a novel cellular immunotherapy that is widely used to treat hematological malignancies, including acute leukemia, lymphoma, and multiple myeloma. Despite its remarkable clinical effects, this therapy has side effects that cannot be underestimated. Cytokine release syndrome (CRS) is one of the most clinically important and potentially life-threatening toxicities. This syndrome is a systemic immune storm that involves the mass cytokines releasing by activated immune cells. This phenomenon causes multisystem damages and sometimes even death. In this study, we reported the management of a patient with recurrent and refractory multiple myeloma and three patients with acute lymphocytic leukemia who suffered CRS during CAR-T treatment. The early application of tocilizumab, an anti-IL-6 receptor antibody, according to toxicity grading and clinical manifestation is recommended especially for patients who suffer continuous hyperpyrexia, hypotensive shock, acute respiratory failure, and whose CRS toxicities deteriorated rapidly. Moreover, low doses of dexamethasone (5-10 mg/day) were used for refractory CRS not responding to tocilizumab. The effective management of the toxicities associated with CRS will bring additional survival opportunities and improve the quality of life for patients with cancer. | Hongli Chen Fangxia Wang Pengyu Zhang Yilin Zhang Yinxia Chen Xiaohu Fan Xingmei Cao Jie Liu Yun Yang Baiyan Wang Bo Lei Liufang Gu Ju Bai Lili Wei Ruili Zhang Qiuchuan Zhuang Wanggang Zhang Wanhong Zhao Aili He | 2019 | Frontiers of Medicine2019,13,5: | 21 |
| 3 | ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer显示文摘 | Shunrong Ji Yi Qin Si Shi Xiangyuan Liu Hongli HU Hu Zhou Jing Gao Bo Zhang Wenyan Xu Jiang Liu Dingkong Liang Liang Liu Chen Liu Jiang Long Haijun Zhou Paul J Chiao Jin Xu Quanxing Ni Daming Gao Xianjun Yu | 2015 | Cell Research2015,25,5: | 19 |
| 4 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015,27,1: | 14 |
| 5 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016,7,2: | 11 |
| 6 | NASICON-structured Na3.1Zr1.95Mg0.05Si2PO12 solid electrolyte for solid-state sodium batteries显示文摘Using stable inorganic solid electrolyte to replace organic liquid electrolyte could significantly reduce potential safety risks of rechargeable batteries. Na-superionic conductor(NASICON)-structured solid electrolyte is one of the most promising sodium solid electrolytes and can be employed in solid-state sodium batteries. In this work, a NASICONstructured solid electrolyte Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) was synthesized through a facile solid-state reaction, yielding high sodium-ionic conductivity of 1.33×10^(-3) S·cm^(-1) at room temperature. The results indicate that Mg^(2+)is a suitable and economical substitution ion to replace Zr^(4+), and this synthesis route can be scaled up for powder preparation with low cost. In addition to electrolyte material preparation, solid-state batteries with Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) as electrolyte were assembled. A specific capacity of 57.9 mAh·g^(-1) is maintained after 100 cycles under a current density of 0.5 C rate at room temperature. The favorable cycling performance of the solid-state battery suggests that Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) is an ideal electrolyte candidate for solid-state sodium batteries. | Jing Yang HongLi Wan ZhiHua Zhang GaoZhan Liu XiaoXiong Xu YongSheng Hu Xia-Yin Yao | 2018 | Rare Metals2018,37,6: | 10 |
| 7 | Progress in ENSO prediction and predictability study显示文摘ENSO is the strongest interannual signal in the global climate system with worldwide climatic, ecological and societal impacts. Over the past decades, the research about ENSO prediction and predictability has attracted broad attention. With the development of coupled models, the improvement in initialization schemes and the progress in theoretical studies, ENSO has become the most predictable climate mode at the time scales from months to seasons. This paper reviews in detail the progress in ENSO predictions and predictability studies achieved in recent years. An emphasis is placed on two fundamental issues: the improvement in practical prediction skills and progress in the theoretical study of the intrinsic predictability limit. The former includes progress in the couple models, data assimilations, ensemble predictions and so on, and the latter focuses on efforts in the study of the optimal error growth and in the estimate of the intrinsic predictability limit. | Youmin Tang Rong-Hua Zhang Ting Liu Wansuo Duan Dejian Yang Fei Zheng Hongli Ren Tao Lian Chuan Gao Dake Chen Mu Mu | 2018 | National Science Review2018,5,6: | 8 |
| 8 | Application of a novel backwashing process in upflow biological aerated filter显示文摘To improve the efficiency of backwashing in upflow biological aerated filter (BAF), a novel backwashing process named air-water siphon backwashing (AWSB) was proposed and applied on laboratory scale. The effects of backwashing on turbidity and suspended solid (SS) in backwashing efluent using this new backwashing process were compared with those of traditional backwashing process, namely air-water backwashing (AWB). In AWB, the turbidity of backwashing efluent maintained 100 NUT when consumed 60 min and 10.5 L water. However, in AWSB, it declined to 44 NUT, consumed 40 min, and 7 L water. The COD removal of BAF after backwashing was also analyzed. The average removal rate of COD in the reactor backwashed by AWB and AWSB was 89.34% and 90.91%, respectively. Compared with AWB, the backwashing interval had been prolonged 35%. The volume of backwashing water in that AWSB was only 66.7% of that in AWB. The results demonstrated that AWSB required less water and took shorter backwashing time relative to AWB to achieve the same turbidity of backwashing efluent, and AWSB was more effective in removing fouling than that of AWB. More significant advantage of AWSB was that the backwashing interval was effectively prolonged. | Jinshui Yang Weijie Liu Baozhen Li Hongli Yuana Meiping Tong Jinsong Gao | 2010 | Journal of Environmental Sciences2010,22,3: | 7 |
| 9 | Two-dimensional ultrathin MoS2-modified black Ti^3+-TiO2 nanotubes for enhanced photocatalytic water splitting hydrogen production显示文摘Two-dimensional (2D) ultrathin MoS2-modified black Ti^3+-TiO2 nanotubes were fabricated using an electrospinning-hydrothermal treatment-reduction method.Bare TiO2 nanotubes were fabricated via electrospinning.Then,2D MoS2 lamellae were grown on the surface of the nanotubes and Ti^3+/Ov ions were introduced by reduction.The photocatalytic performance of the 2D MoS2/Ti^3+-TiO2 nanotubes was^15 times better than that of TiO2.The HER enhancement of the MoS2/Ti^3+-TiO2 nanotubes can be attributed to the Pt-like behavior of 2D MoS2 and the presence of Ti^3+-ions,which facilitated the quick diffusion of the photogenerated electrons to water,reducing the H2 activation barrier.The presence of Ov ions in the nanotubes and their hollow structure increased their solar utilization. | Wei Ou Jiaqi Pan Yanyan Liu Shi Li Hongli Li Weijie Zhao Jingjing Wang Changsheng Song Yingying Zheng Chaorong Li | 2020 | Journal of Energy Chemistry2020,29,4: | 7 |
| 10 | Smart CU1.75S nanocapsules with high and stable photothermal efficiency for NIR photo-triggered drug release显示文摘Thermosensitive 药交货系统(DDS ) 面对主要挑战,例如遥远、可重复的控制在 vivo 温度,尽管这些能增加药的治疗学的功效。处理这个问题,我们涂在红外线附近(NIR ) photothermal Cu 1.75 有 pH/thermos-sensitive 聚合物由的 S nanocrystals 在 situ 聚合。装载内容的 doxorubicine (纪录影片) 直到 40 wt.% ,与纪录影片在正常生理的条件下面正在被漏的不到 8.2 wt.%(pH = 7.4, 37 吗? | Sheng Huang Jing Liu Qian He Hongli Chen Jiabin Cui Suying Xu Yuliang Zhao Chunying Chen Leyu Wang | 2015 | Nano Research2015,8,12: | 7 |
| 11 | Formation control with obstacle avoidance of second-order multi-agent systems under directed communication topology显示文摘This paper addresses the obstacle avoidance problem of formation control for the multi-agent systems modeled by double integrator dynamics under a directed interconnection topology. The control task is finished by a leader-follower formation scheme combined with an artificial potential field(APF) method.The leader-follower scheme is carried out by taking the desired trajectory with the desired velocity as virtual leader, while the APF method is carried out by dealing with the obstacles as the high potential points. When the obstacle avoidance tasks are finished, the artificial potential forces degrade the formation performance, so their undesired effects are treated as disturbances, which is analyzed by the robust H∞performance. Based on Lyapunov stability theory, it is proved that the proposed formation approach can realize the control objective. The result is also extended to the switching multi-agent formation. The effectiveness of the proposed formation scheme is further confirmed by simulation studies. | Guoxing WEN CLPhilip CHEN Hui DOU Hongli YANG Chunfang LIU | 2019 | Science China(Information Sciences)2019,62,9: | 7 |
| 12 | Simulated analysis of summer climate on centennial time scale in eastern China during the last millennium显示文摘Using Lanczos filtered simulation results from the ECHO-G coupled ocean-atmosphere model,this study analyzes the spatiotemporal structure of temperature and precipitation on centennial time scale to examine how climate change in eastern China responded to external forcing during the last millennium.The conclusions are (1) eastern China experienced a warm-cold-warm climate transition,and the transition from the warm period to the cold period was slower than the cold to warm transition which followed it.There was more rainfall in the warm periods,and the transitional peak and valley of precipitation lag those of temperature.The effective solar radiation and solar irradiance have significant impacts on the temporal variation of both temperature and precipitation.Volcanic activity plays an important role in the sudden drop of temperature before the Present Warm Period (PWP).There is a positive correlation between precipitation and volcanic activity before 1400 A.D.,and a negative relationship between the two thereafter.The concentration of greenhouse gases increases in the PWP,and the temperature and precipitation increase accordingly.(2) The spatial pattern of the first leading empirical orthogonal function (EOF) mode of temperature on centennial time scale is consistent with that on the inter-annual/inter-decadal (IA-ID) time scales;namely,the entirety of eastern China is of the same sign.This pattern has good coherence with effective solar radiation and the concentrations of greenhouse gases.The first leading EOF mode of precipitation on centennial time scale is totally different from that on the IA-ID time scales.The first leading mode of centennial time scale changes consistently over the entirety of eastern China,while the middle and lower reaches of the Yangtze and Yellow Rivers are the opposite to the rest of eastern China is the leading spatial pattern on IA-ID time scale.The distribution of precipitation on centennial time scale is affected by solar irradiance and greenhouse gas concentrations. | WANG HongLi LIU Jian WANG ZhiYuan WANG SuMin KUANG XueYuan | 2011 | Chinese Science Bulletin2011,56,21: | 6 |
| 13 | Caveolin proteins: a molecular insight into disease显示文摘 | Hongli Yin Tianyi Liu Ying Zhang Baofeng Yang | 2016 | Frontiers of Medicine2016,10,4: | 6 |
| 14 | Multichannel radar adaptive signal detection in interference and structure nonhomogeneity显示文摘In this paper, we consider the problem of multichannel radar signal detection in interference and structure nonhomogeneity. The interference is often caused by electromagnetic countermeasure(ECM) systems or industrial activity, while the nonhomogeneity usually arises because of rapid variations in terrain or radar antenna structure. We propose three adaptive detectors according to three common criteria of detector design, namely, the generalized likelihood ratio test(GLRT), Rao test, and Wald test. Extensive performance comparisons are conducted under different scenarios. It is shown that when the nonhomogeneity is severe, the detector devised according to the GLRT achieves the best detection performance. In other scenarios, the detector designed according to the Wald test may be the best choice, which has the highest probability of detection. | Weijian LIU Hui HAN Jun LIU Hongli LI Kai LI Yong-Liang WANG | 2017 | Science China(Information Sciences)2017,60,11: | 6 |
| 15 | Artificial Hair-Like Sensors Inspired from Nature: A Review显示文摘 | Zhiwu Han Linpeng Liu Kejun Wang Honglie Song Daobing Chen Ze Wang Shichao Niu Junqiu Zhang Luquan Ren | 2018 | Journal of Bionic Engineering2018,15,3: | 6 |
| 16 | Multisite co-allocation scheduling algorithms for parallel jobs in computing grid environments显示文摘Cooperation of multi-domain massively parallel processor systems in com- puting grid environment provides new opportunities for multisite job scheduling. At the same time, in the area of co-allocation, heterogeneity, network adaptability and scalability raise the challenge for the international design of multisite job scheduling models and algorithms. It presents multisite job scheduling schema through the introduction of mul- tisite job scheduling model and the performance model under the grid environment. It introduces two job multisite and cooperative scheduling models and algorithms with the core of the optimal and greedy-heuristic resource selection strategies. Meanwhile, com- pared with single and multisite cooperative scheduling models and algorithms introduced by Sabin, Yahyapour and other persons, the validity and advance of the scheduling model and the performance model herein are proved. | ZHANG Weizhe FANG Binxing HU Mingzeng LIU Xinran ZHANG Hongli GAO Lei | 2006 | Science in China(Series F)2006,49,6: | 4 |
| 17 | Rolling Bearing Feature Frequency Extraction using Extreme Average Envelope Decomposition显示文摘The vibration signal contains a wealth of sensitive information which reflects the running status of the equipment. It is one of the most important steps for precise diagnosis to decompose the signal and extracts the effective information properly. The traditional classical adaptive signal decomposition method, such as EMD, exists the problems of mode mixing, low decomposition accuracy etc. Aiming at those problems, EAED(extreme average envelope decomposition) method is presented based on EMD. EAED method has three advantages. Firstly, it is completed through midpoint envelopment method rather than using maximum and minimum envelopment respectively as used in EMD. Therefore, the average variability of the signal can be described accurately. Secondly, in order to reduce the envelope errors during the signal decomposition, replacing two envelopes with one envelope strategy is presented. Thirdly, the similar triangle principle is utilized to calculate the time of extreme average points accurately. Thus, the influence of sampling frequency on the calculation results can be significantly reduced. Experimental results show that EAED could separate out single frequency components from a complex signal gradually. EAED could not only isolate three kinds of typical bearing fault characteristic of vibration frequency components but also has fewer decomposition layers. EAED replaces quadratic enveloping to an envelope which ensuring to isolate the fault characteristic frequency under the condition of less decomposition layers. Therefore, the precision of signal decomposition is improved. | SHI Kunju LIU Shulin JIANG Chao ZHANG Hongli | 2016 | Chinese Journal of Mechanical Engineering2016,29,5: | 4 |
| 18 | Uniformed model of networked control systems with long time delay显示文摘Feedback control systems wherein the control loops are closed through a real-time network are called networked control systems (NCS). The defining feature of an NCS is that information is exchanged using a network among control system components. Two new concepts including long time delay and short time delay are proposed. The sensor is almost always clock driven. The controller or the actuator is either clock driven or event driven. Four possible driving modes of networked control systems are presented. The open loop mathematic models of networked control systems with long time delay are developed when the system is driven by anyone of the four different modes. The uniformed modeling method of networked control systems with long time delay is proposed. The simulation results are given in the end. | Zhu Qixin Liu Hongli Hu Shousong | 2008 | Journal of Systems Engineering and Electronics2008,19,2: | 4 |
| 19 | A comparative investigation into floatability of bastnaesite with three di/trialkyl phosphate surfactants显示文摘Flotation separation and recovery of rare earth minerals(REM) have returned to an important position due to the growing strategy demand for rare earth elements(REE).In this paper,a comparative investigation into the floatability of bastnaesite((Ce,La)FCO3) was conducted by using three di/trialkyl phosphate collectors,di(2-ethylhexyl) phosphate(DEHPA),dibutyl phosphate(DBP) and tributyl phosphate(TBP).The density functional theory(DFT) computation recommends that the chemical activity of the three phosphate collectors is in order of DEHPA≥ DBP >> TBP,and their hydrophobization assuggested by the IgP(oil-water partition coefficient) value is in the order of DEHPA> TBP> DBP.The micro-flotation indicates that the preferable pH values for flotation of bastnaesite with the three phosphate collectors are 7.0-8.0,and DEHPA achieves much higher flotation recovery of bastnaesite,followed by DBP,and then TBP,which coincides with their reactivity and hydrophobicity,the two prerequisites for froth flotation.The contact angle,zeta potential,Fourier transform infrared spectroscopy(FTIR) and X-ray photoelectron spectroscopy(XPS) deduce that DEHPA likely reacts with the Ce(Ⅲ)atoms of bastnaesite interface through its O atom(s) of the P(=O)-O-group to generate the Ce-O-P bonds,and its two 2-ethylhexyl groups orient outside for attaching bubbles,resulting in flotation enrichment of bastnaesite.Furthermore,this investigation offers a novel strategy for developing collectors in selective beneficiation of REM. | Hongli Fan Xianglin Yang Jing Qi Guangyi Liu Jingqin Qin | 2021 | Journal of Rare Earths2021,39,11: | 3 |
| 20 | Anti-disturbance filter design for a class of stochastic systems with fading channels显示文摘Dear editor,As a significant topic in control and signal processing communities,the filtering problem has been attracting persistent research attention in the past few decades[1].In practical engineering,the parameter perturbations are unavoidable due mainly to exogenous disturbances,environmental changes and some other phenomena. | Yang LIU Zidong WANG Hongli DONG Hongjian LIU | 2020 | Science China(Information Sciences)2020,63,11: | 3 |