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732篇 您的检索式：作者名="Hamilton D J"

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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	Antisense gene that inhibits synthesis of the hormone ethylene in transgenic plant 显示文摘	Hamilton A J Yycett G W Grierson D	1990	Nature1990，346，：	2
3	The elastic compensation method for limit and shakedown analysis:a review显示文摘	D Mackenzie J T Boyle R Hamilton	2000	Journal of Strain Analysis2000，35，3：	1
4	Antisense gene that inhibit synthesis of hormone ethylene in transgenic plants 显示文摘	Hamilton A J Lyett G W Grierson D	1990	Nature1990，346，6281：	1
5	C-2 neurec-tomy during atlantoaxial instrumented fusion in the elderly: patient satisfaction and surgical outcome 显示文摘	Hamilton D K Smith J S Sansur C A	2011	J Neurosurg Spine2011，15，1：	1
6	Oil and the Macroeconomy since World War II显示文摘	Hamilton J D	1983	Journal of Political Economy1983，，2：	1
7	Evidence for a male-produced sex pheromone in the western flower thrips Frankliniella occidentals显示文摘	Kirk W D J Hamilton J G C		0，，01：	1
8	Optical propertiesof cubic SiC:luminescence of nitrogen-exciton complexes,and interband absorption显示文摘	Choyke W J Hamilton D R Patrick L	1964	Physical Review1964，133，4：	1
9	A species of small antisense RNA in post transcriptional gene silencing in plants显示文摘	HAMILTON A J BAULCOMBE D C	1999	Science1999，286，5441：	1
10	An investigation of the route and progression of encephalitozoon cuniculi infection in adult rabbits显示文摘	Cox J C Hamilton R C Attwood H D	1979	J Protozool1979，26，1：	1
11	Simplified lower bound limit analysis of pressurized cylinder/cylinder intersections using generalized yield criteria显示文摘	R Hamilton D Mackenzie J Shi J T Boyle	1996	Int J Pres Ves and Piping1996，67，2：	1
12	Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘	Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R	2009	Journal of Bacteriology2009，191，16：	1
13	A new approach to the economic analysis of nonstationary time series and the business cycle 显示文摘	Hamilton J D	1989	Econometrica1989，57，：	1
14	A new approach to the economic anal- ysis of nonstationary time series and the business cycle 显示文摘	HAMILTON J D	1989	Econometrica1989，57，：	1
15	An eoclassical model of unemployment and the business cycle显示文摘	Hamilton J D	1988	Journal of Political Economy1988，96，3：	1
16	A species of small antisens RNA in post transcriptional gene silencing in plants显示文摘	Hamilton A J Baulcombe D C	1999	Science1999，286，5441：	1
17	Feline ilial fractures:assessment of screw loosening and pelvic canal narrowingafter lateral plating显示文摘	Hamilton M H Evans D A Langley-Hobbs S J	2009	Vet Surg2009，38，：	1
18	A theory of lubrication by microirregulafities显示文摘	Hamilton D Walowit J Allen C	1966	Journal of Fluids Engineering1966，88，1：	1
19	A species of small antisense RNA in posttranscriptional gene silencing in plants显示文摘	BAULCOMBE D C	1999	Science1999，286，：	1
20	A theory of lubrication by micro-irregularities显示文摘	Hamilton D B Walawit J A Allen C M	1966	ASME Journal of Basie Engineering1966，88，1：	1

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