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| 1 | Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy显示文摘Mesenchymal stem cells(MSCs) are a pleiotropic population of cells that are self-renewing and capable of differentiating into canonical cells of the mesenchyme, including adipocytes, chondrocytes, and osteocytes. They employ multi-faceted approaches to maintain bone marrow niche homeostasis and promote wound healing during injury. Biomedical research has long sought to exploit their pleiotropic properties as a basis for cell therapy for a variety of diseases and to facilitate hematopoietic stem cell establishment and stromal reconstruction in bone marrow transplantation. Early results demonstrated their usage as safe, and there was little host response to these cells. The discovery of their immunosuppressive functions ushered in a new interest in MSCs as a promising therapeutic tool to suppress inflammation and down-regulate pathogenic immune responses in graft-versus-host and autoimmune diseases such as multiple sclerosis, autoimmune diabetes, and rheumatoid arthritis. MSCs produce a large number of soluble and membrane-bound factors, some of which inhibit immune responses. However, the full range of MSC-mediated immune-modulation remains incompletely understood, as emerging reports also reveal that MSCs can adopt an immunogenic phenotype, stimulate immune cells, and yield seemingly contradictory results in experimental animal models of inflammatory disease. The present review describes the large body of literature that has been accumulated on the fascinating biology of MSCs and their complex effects on immune responses. | Justin D Glenn Katharine A Whartenby | 2014 | World Journal of Stem Cells2014，6，5： | 55 |
| 2 | Insular biogeography of mammals in Ca-nadian parks显示文摘 | Glenn S M Nudds T D | 1989 | Journal of Biogeography1989，16，3： | 1 |
| 3 | Accuracy of sleep perceptions among insomnia sufferers and normal sleepers 显示文摘 | MEANS M K EDINGER J D GLENN D M | 2003 | Sleep Med2003，4，4： | 1 |
| 4 | Molecular biology of the natriuretic peptide system: implications for physiology and hypertension 显示文摘 | Gardner D G Chen S Glenn D J | 2007 | Hypertension2007，49，3： | 1 |
| 5 | Methods for the Detection of Polyether Ionophore Residues in Poultry显示文摘 | Christopher T Elliott D Glenn Kennedy W John McCaughey | 1998 | Analyst1998，123，： | 1 |
| 6 | Acousto-Optic Tunable Flters: Fundamentals and Applications as Applied to Chemical Analysis Techniques显示文摘 | Ling B Glenn I D Heather M M | 2004 | Progress in Quantum Electronics2004，，28： | 1 |
| 7 | Fast, free breathing,in vivo fetal imaging using time-resolved 3D MRI technique: preliminary results显示文摘 | Liu J Glenn OA Xu D | 2014 | Quant Imaging Med Surg2014，4，2： | 1 |
| 8 | Daytime testing after laboratory of home-base polysomnograply comparisons of middle-aged insomnia sufferers and normal sleepers显示文摘 | Edinger J O Glenn D M Bastian L A | 2003 | J sleep Res2003，12，1： | 1 |
| 9 | Classification and regression trees: A powerful yet simple technique for ecological data analysis 显示文摘 | Glenn D Katharina E | 2000 | Ecology2000，81，11： | 1 |
| 10 | Changes in the risk of fine-root mortality with age:a case study in peach,Prunus persica(Rosaceae)显示文摘 | Wells C E Glenn D M Eissenstat D M | 2002 | American Journal of Botany2002，89，1： | 1 |
| 11 | Encapsulation of plant oils in porous starch microspheres显示文摘 | Glenn G M Klamczynski A P Woods D F | 2010 | Journal of Agricultural and Food Chemistry2010，58，7： | 1 |
| 12 | Reactivity of vapor-deposited metal atoms with nitrogen-containing poly- mers and organic surfaces studied by in situ XPS显示文摘 | Anthony J W Glenn M W Fairbrother D H | 2003 | Applied Surface Science2003，219，34： | 1 |
| 13 | Molecular biolo- gy of the natriuretic peptide system : implications for physiology and hypertension 显示文摘 | GARDNER D G CHEN S GLENN D J | 2007 | Hypertension2007，49，： | 1 |
| 14 | Observer design of critical states for air path flow regulation in a variable geometry turbocharger exhaust gas recirculation diesel engine 显示文摘 | Glenn B C Upadhyay D Utkin V L | 2011 | International Journal of Vehicle Design2011，12，6： | 1 |
| 15 | The FED' s exit strategy for monetary policy 显示文摘 | GLENN D R | 2010 | Frbsf Economic Letter2010，，6： | 1 |
| 16 | Determination of the furazolidone metabolite, 3 -amino -2 -oxazonamone,in porcine tissues liquid chromatographythermospray mass spectrometry and the occurrence of residues in pigs produced in Northern Ireland 显示文摘 | ROBERT J MCCRACKEN D GLENN KENNEDY | 1997 | Joumal of Chromatography B1997，，691： | 1 |
| 17 | Early tracheotumy in elderly patients results in less ventilator- associated pneumonia显示文摘 | Glenn TS Nathan MD Timothy D | 2009 | Otolaryngol- Head Neck Surg2009，140，2： | 1 |
| 18 | SeaSonde is integral to coastal flow model development显示文摘 | KOHUT J GLENN S BARRICK D E | 1999 | Hydro Int1999，3，： | 1 |
| 19 | A reflective, processed-kaolin particle film affects fruit tempera- ture, radiation reflection, and solar in-jury in apple 显示文摘 | Glenn D M Prado E Erez A | 2002 | Journal of the American Society for Horticultur- al Science2002，127，： | 1 |
| 20 | New acetyls techonologies from BP chemicals显示文摘 | Mark J Howard Glenn J Sunley Andrew D Poole Robert J Watt Bhushan K Sharma | 1999 | Studies in Surface Science and Catalysis1999，，： | 1 |
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