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| 1 | 睾丸活检:临床操作及其诠释显示文摘睾丸活检许多年来被认为是不明病因男性不育和无精症诊断的基础。近来,男性不育指南都限定诊断性睾丸活检只能用于梗阻性无精子症(睾丸体积正常,生殖激素正常)的鉴别诊断。现今,睾丸活检取精技术与胞浆内单精子显微注射(ICSI)联用于非梗阻性无精子症患者的取精过程中。此外,睾丸活检还可以应用于有睾丸恶性肿瘤风险的患者的取精治疗中。研究一些不育男性后发现,不育患者患原位睾丸癌的风险越来越高,尤其是曾有隐睾症、睾丸恶性肿瘤病史,或患睾丸萎缩的患者。睾丸超声异常,比如睾丸微石症,实质内呈弥散分布,软细胞组织不均、睾丸组织损伤等,进一步增加了这些患者原位癌的发病率。准确的组织学分类,正确的组织处理和固定,样品准备和评估是必须的。同时,推荐使用标准的睾丸活检方法。另外,通过免疫组织化学法检测睾丸组织的肿瘤恶化程度是不可缺少的技术支持。本综述主要描述了睾丸活检用于男性不育临床诊断和治疗措施的最新进展。 | Gert R Dohle Saad Elzanaty Niels J van Casteren | 2012 | Asian Journal of Andrology2012,14,1: | 13 |
| 2 | 中国的低碳转型与生态现代化显示文摘生态现代化理论探讨了国家在社会体制、经济发展和社会思想意识形态等方面的生态化转向,为政府、企业以及非政府团体和个人在面对环境问题时应该如何做出调整提供了一种新的思路。本文综述了生态现代化理论的核心思想和基本要素,并探讨了该理论发展过程中的主要争论。考虑目前国内经济的发展动态和发展低碳经济的迫切需求,这一理论对推动我国经济的低碳转型有着重要的借鉴意义。尤其是该理论发展过程中关于生产与消费的讨论,更为探讨发展低碳经济的核心定位等问题提供了参考。结合生态现代化观点和争论,本文提出我国经济的低碳转型,需要从尤其强调生产端导向的碳减排向同时兼顾上下游并重视消费者作用的战略思路转变;经济变革同时强调制度变革,转变行政命令控制为主的规制格局,促进多角色的参与;作为生产的微观主体,企业需强调以保护生态为己任的机构和管理改革,长远的发展更需要构建一种生产者与消费者之间有效衔接的消费导向战略。这些转变都将有利地推动中国经济的低碳现代化。 | 刘文玲 王灿 Spaargaren Gert Mol Arthur P J | 2012 | 中国人口·资源与环境2012,22,9: | 8 |
| 3 | Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn’s disease: an open randomised trial显示文摘 | Geert D’Haens Filip Baert Gert van Assche Philip Caenepeel Philippe Vergauwe Hans Tuynman Martine De Vos Sander van Deventer Larry Stitt Allan Donner Severine Vermeire Frank J Van De Mierop Jean-Charles R Coche Janneke van der Woude Thomas Ochsenkühn Ad A | 2008 | The Lancet2008,,9613: | 5 |
| 4 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis: Special situations显示文摘 | Gert Van Assche Axel Dignass Bernd Bokemeyer Silvio Danese Paolo Gionchetti Gabriele Moser Laurent Beaugerie Fernando Gomollón Winfried H?user Klaus Herrlinger Bas Oldenburg Julian Panes Francisco Portela Gerhard Rogler Jürgen Stein Herbert Tilg Simon Tra | 2012 | Journal of Crohn’s and Colitis2012,,: | 4 |
| 5 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006,12,28: | 2 |
| 6 | Potential therapeutic benefits stemming from the thermal nature of irreversible electropora tion of solid cancers显示文摘To the Editor:Irreversible electroporation(IRE)is a CE-and FDAapproved treatment modality for pancreatic and liver tumors that is based on the site-confined destruction of tumor tissue by multiple short,high-intensity electrical pulses.^([1])Currently there is a heated debate about whether the therapy is thermal or non-thermal.The'non-thermal proponents'advocate | Michal Heger Allard C van der Wal Gert Storm Martin J van Gemert | 2015 | Hepatobiliary & Pancreatic Diseases International2015,14,3: | 2 |
| 7 | Levels of C-reactive Protein Are Associated With Response to Infliximab Therapy in Patients With Crohn’s Disease显示文摘 | Matthias Jürgens Jestinah M. Mahachie John Isabelle Cleynen Fabian Schnitzler Herma Fidder Wouter van Moerkercke Vera Ballet Maja Noman Ilse Hoffman Gert van Assche Paul J. Rutgeerts Kristel van Steen Severine Vermeire | 2011 | Clinical Gastroenterology and Hepatology2011,,5: | 2 |
| 8 | Rapid determination of particle velocity from space-time images using the Radon transform 显示文摘 | Drew P J Pablo B Gert C | 2010 | Journal of Computational Neuro- science2010,29,1: | 1 |
| 9 | Leptin impairs metabolic action of insulin in isolated rat adipocytes 显示文摘 | Ertl J Gert M | 1997 | J Biol Chem1997,272,10: | 1 |
| 10 | Efficacy and dietary inplications for the use of plant sterol-enriched foods to lower total and low-density lipoprotein cholesterol levels 显示文摘 | Sachiko T Ernst J Gert W | 2000 | Top Clinical Nutrition2000,15,4: | 1 |
| 11 | Improvement in caecal intubation rate and pain reduction by using 3-dimensional magnetic imaging for unsedated colonoscopy: A randomized trial of patients referred for colonoscopy显示文摘 | Geir Hoff Michael Bretthauer Stein Dahler Gert Huppertz-Hauss Jostein Sauar J?rn Paulsen Birgitte Seip Volker Moritz | 2007 | Scandinavian Journal of Gastroenterology2007,,7: | 1 |
| 12 | Molecular characterization of a Galactomyces geotrichum lipase,another member of the cholinesterase/lipase family显示文摘 | Pretorius Gert H J Van Rensburg H G | 1995 | Biochimica et Biophysica Acta1995,,1252: | 1 |
| 13 | Liquid crystalline perylene-3, 4-dicarboximide derivatives with high thermal and photochemical stability显示文摘 | CHRISTIAN M VOLKER E | 1998 | Materials Science1998,81,1: | 1 |
| 14 | Push-off force in speed skating 显示文摘 | Koning J J de R W de Boer Gert de Groot and G J van Ingen Schenau | 1987 | Sport Biomech1987,,3: | 1 |
| 15 | Adaptations of a comparison technique for terrain navigation ☆ ☆ This article was presented at the German Aerospace Congress 2004.显示文摘 | Jürgen Metzger Oliver Meister Gert F. Trommer Franz Tumbr?gel Bernd Taddiken | 2005 | Aerospace Science and Technology2005,,6: | 1 |
| 16 | Food safety and transparency in food chains and networks显示文摘 | Adrie J M Beulens Douwe-Frits Broens Peter Folstar Gert Jan Hofst- ede | 2005 | Food Control2005,,16: | 1 |
| 17 | Coor- dination of leg muscles during speed skating显示文摘 | Jos J de Koning Gert de Groot Gerrit Jan van Ingen Schenau | 1991 | Biomechanics1991,,24: | 1 |
| 18 | Oncogene alterations in carcinomas of the uterine cervix:overexpression of the epidermal growth factor receptor is associated with poor prognosis显示文摘 | Anne-Marie F K Gert J F | 1999 | Clinical Cancer Reserch1999,5,: | 1 |
| 19 | Tribological Properties of Nanocomposite CrC x /a-C:H Thin Films显示文摘 | Gert Gassner J?rg Patscheider Paul H. Mayrhofer Saso ?turm Christina Scheu Christian Mitterer | 2007 | Tribology Letters2007,,1: | 1 |
| 20 | Bridge-Output-To-Frequency Converter for Smart Thermal Air-Flow Sensors显示文摘 | Gert J A van Dijk Johan H Huijsing | 1995 | IEEE Transactions on Instrumentation and Measurement1995,44,4: | 1 |