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    题名 作者 年代 出处 被引量
1Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease显示文摘BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)refers to any fatty liver disease that is not due to excessive use of alcohol.NAFLD probably results from abnormal hepatic lipid metabolism and insulin resistance.Aerobic exercise is shown to improve NAFLD.This review aimed to evaluate the molecular mechanisms involved in the beneficial effects of aerobic exercise on NAFLD.DATA SOURCE:We searched articles in English on the role of aerobic exercise in NAFLD therapy in Pub Med.Rui Guo Emily C Liong Kwok Fai So Man-Lung Fung George L Tipoe 2015Hepatobiliary & Pancreatic Diseases International2015,14,2:16
2Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges显示文摘BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver injury and mortality in Western countries and China. However, as to date, there is no direct and effective therapy for this disease. The aim of this review is to analyze the key progress and challenges of main current therapeutic approaches in NAFLD. DATA SOURCE: We carried out a PubMed search of English-language articles relevant to NAFLD therapy. RESULTS: There are two major therapeutic strategies for NAFLD treatment: (1) lifestyle interventions (including weight reduction, dietary modification and physical exercise) and (2) pharmaceutical therapies. Lifestyle interventions, particularly chronic and moderate intensity exercise, are the most effective and recognized clinical therapies for NAFLD. For pharmaceutical therapies, although their effects and mechanisms have been extensively investigated in laboratory studies, they still need further tests and investigations in clinical human trials. CONCLUSION: Future advancement of NAFLD therapy should focus on the mechanistic studies on cell based and animal models and human clinical trials of exercise, as well as the combination of lifestyle intervention and pharmaceutical therapy specifically targeting main signaling pathways related to lipid metabolism, oxidative stress and inflammation.Jia Xiao Rui Guo Man Lung Fung Emily C Liong George L Tipoe 2013Hepatobiliary & Pancreatic Diseases International2013,12,2:14
3Optimization of an impact drive mechanism based on real-coded genetic algorithm 显示文摘Ha J L Fung R F Han C F 2005Sensors and Actuators2005,121,2:1
4Non-structural Fuzzy Decision Support System for Evaluation of Construction Safety Management System显示文摘Tam C M Tong Thomas K L Chiu Gerald C W Fung Ivan W H 2002International Journal of Project Management2002,,20:1
5Optimization of an impact drive mechanism based on real-coded genetic algorithm显示文摘Ha J L Fung R F Han C F 0,,02:1
6Psychometric properties of the Chinese version of the mini-mental adjustment to cancer (MINI-MAC) scale显示文摘Ho S M Y Kam Fung W Chan C L W 2003Psycho Oncol2003,12,6:1
7Fascin expression predicts survival after potentially curative resection of node-positive colon cancer显示文摘Chan C Jankova L Fung CL 0,,:1
8Analysis of residual stresses and distortion in T-joint filler welds显示文摘Teng T L Fung C P Chang P H 2001Intemational Journal of Pressure Vessel and Piping2001,78,:1
9Modeling of cavity stability and sand production in heavy oil reservoir显示文摘Fung L S K Wong R C K 1996JCPT1996,35,2:1
10Early-stage bilateral breast cancer reated with breast conserving surgery and definitive irradiation: the University of Pennsylvania experience显示文摘Fung M C Scthultz D J Solin L J 1997Radiat Oncol Biol Phys1997,38,5:1
11Diameter-defined Strahler system and connectivity matrix of the pulmonary arterial tree显示文摘Jiang Z L Kassab G S Fung Y C 1994J Appl Physiol1994,76,2:1
12Improving the wind environment in high-density cities by understanding urban morphology and surface roughness : A study in Hong Kong显示文摘Ng E Yuan C Chert L Ren C Fung J C H 2011Landscape Urban Plan2011,101,1:1
13Decreased CD4^+ CD25 ^+ T Cells in peripheral blood of patients with systemic lupus erythematosus显示文摘LIU M F WANG C R FUNG L I 2004Scand J Immunol2004,59,:1
14Partial hydatidiform mole: ultrasonographic features显示文摘WOO J S K HSU C FUNG L L Y 1983Aust NZJ Obstet Gynecol1983,23,:1
15Dynamic modeling and vibration analysis of a flexible cable-stayed beam structure 显示文摘Fung R F Lu L Y Huang S C 2002Journal of Sound and Vibration2002,254,:1
16L lymphoma of the ocular adnexa:A study of 353 cases显示文摘Ferry J A Fung C Y Zukerberg L 2007Am J Surg Pathol2007,31,2:1
17An assessment indicator for air ventilation and pollutant dispersion potential in an urban canopy with complex natural terrain and significant wind variations显示文摘S H L Yim J C H Fung E Y Y Ng 2014Atmospheric Environment2014,,94:1
18Synthesis of acyclic dinucleating phenanthroline-pyridine and phenanthroline-phosphine ligands显示文摘 KAISHING C BANGJI L 1995Tetrahedron Letters1995,36,35:1
19Modeling of cavity stability and sand production in heavy oil reservoirs显示文摘Fung L S K Wong R C K 1996Journal of Canadian Petroleum Technology1996,35,2:1
20Augmentation of hypoxia-induced nitric oxide generation in the rat carotid body adapted to chronic hypoxia:an involvement of constitutive and inducible nitric oxide synthases显示文摘 Tipoe G L Fung P C 2002Pflugers Arch2002,444,85:1
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