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| 1 | Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome显示文摘BackgroundThere 是在质子泵禁止者(PPI ) 和 clopidogrel 之间的可能的不利相互作用上的大争论。另外, PPI 的使用是否少些影响 ticagrelor 遗体的临床的功效,知道。在经皮的冠的干预(一种总线标准) .MethodsWe 回顾地从 “ 分析了数据以后,我们试图与急性冠的症候群(交流)在病人在临床的结果上决定 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响;真实 world” ;,国际,在 2003 和 2014 之间的多中心登记( n = 15,401 )并且在1年的合成主要端点上估计了 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响(所有原因死亡收到 PPI 的病人更老,更经常女性,并且是更可能的有 comorbidities。没有协会为收到 clopidogrel 的病人在 PPI 使用和主要端点之间被观察(调整 HR:1.036;95% CI:0.903-1.189 ) 或 ticagrelor (调整 HR:2.320;95% CI:0.875-6.151 )(P 相互作用 = 0.2004 ) 。同样, PPI 的使用没与所有原因死亡,重新梗塞,或与交流后面的一种总线标准的为与任何一个 clopidogrel 对待的病人或 ticagrelor.ConclusionsIn 病人的严重流血的减少的风险的增加的风险被联系, PPI 的伴随物使用没在收到 clopidogrel 或 ticagrelor 的病人与不利结果的增加的风险被联系。我们的调查结果显示与 clopidogrel 或 ticagrelor 在联合使用 PPI 是合理的,特别在有胃肠的流血的更高的风险的病人。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzfilez-Juanatey Stephen B Wilton Wouter J Kikkert Ivlin Nufiez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiril Sasko Kedev | 2016 | Journal of Geriatric Cardiology2016，13，3： | 12 |
| 2 | P2Y12受体抑制剂联合质子泵抑制剂对急性冠脉综合征患者缺血事件影响的临床分析显示文摘目的本研究旨在分析P2Y12受体抑制剂联合质子泵抑制剂(PPI)治疗对经皮冠状动脉介入(PCI)术后的急性冠脉综合征患者缺血事件的影响。方法基于国际多中心回顾性注册登记研究,纳入2003至2014年因急性冠脉综合征人院行PCI术的患者,分为PPI组及非PPI组并随访1年,主要临床终点为全因死亡/再发心肌梗死的复合终点。根据P2Y12受体抑制剂种类,将入组患者分为氯吡格雷组及替格瑞洛组,并比较不同药物与PPI联用发生临床终点事件的风险。结果研究入选9429例患者,PPI组占54.8%,具有更多高危因素。Cox回归结果提示PPI组较非PPI组全因死亡/再发心肌梗死复合事件的发生差异无统计学意义(HR1.00,95%CI 0.86—1.18)。根据P2Y12抑制剂种类不同分为氯吡格雷组和替格瑞洛组,不同P2Y12受体抑制剂联用PPI较未联用PPI患者的临床终点无差异,联用PPI的氯吡格雷组与替格瑞洛组的临床终点差异也无统计学意义。结论急性冠脉综合征患者PPI与P2Y12受体抑制剂联用不增加全因死亡和再发心肌梗死风险,尤其PPI联用氯吡格雷在患者的缺血事件上与替格瑞洛比较差异无统计学意义。 | 冯斯婷 严妍 范婧尧 王晓 郑文 聂绍平 Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D' Ascenzo Jorge Saucedo Jose R Conzalez-Juanatey Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiri Sasko Kedev | 2016 | 中华医学杂志2016，96，33： | 6 |
| 3 | Anatomic hepatectomy as a definitive treatment for hepatolithiasis: a cohort study显示文摘 | Nicolás Jarufe Eduardo Figueroa César Mu?oz Fabrizio Moisan Julian Varas José R. Valbuena Claudia Bambs Jorge Martínez Fernando Pimentel | 2012 | HPB2012，，9： | 2 |
| 4 | Direct anterior approach hip arthroplasty:How to reduce complications-A 10-years single center experience and literature review显示文摘BACKGROUND The direct anterior approach for total hip arthroplasty(DAA-THA)is increasing in popularity due to some advantages such as less surgical trauma,minimal dissection of soft tissues,shorter rehabilitation times,faster return to daily activities,lower incidence of dislocation.On the other hand,the literature reports a high rate of intraoperative complications,with many different rates and complication types in the published papers.AIM To analyze our complications comparing results with the literature;to report measures that we have taken to reduce complications rate.METHODS All DAA-THA patients with one year minimum follow up who were operated at a single high-volume centre,between January 2010 and December 2019 were included in this retrospective study.All surgeries were performed using cementless short anatomical or straight stems and press fit cups.Patients’followup was performed,at 6 wk,3 mo,then annually post-surgery with clinical and radiological evaluation.Primary outcomes were stem revision for aseptic loosening and all-cause stem revision.Second outcome was intra-operative and post-operative complications identification.RESULTS A total of 394 patients underwent DDA-THA from January 2010 and December 2019,for a total of 412 hips;twelve patients lost to follow-up and one patient who died from causes not related to surgery were excluded from the study.The average age at the time of surgery was 61 years(range from 28 to 78 years).Mean follow-up time was 64.8 mo(range 12-120 mo).Seven stems were revised.One cortical perforation,one trochanteric and lateral cortical wall intraoperative fracture,one diaphyseal fracture,three clinically symptomatic early subsidence and one late aseptic loosening.We also observed 3 periprosthetic fractures B1 according to the Vancouver Classification.Other minor complications not requiring stem revision were 5 un-displaced fractures of the calcar region treated with preventive cerclage,one early infection,one case of late posterior dislocation,18 case of asymptomatic stem subsidence,6 cases of lateral cutaneous femoral nerve dysesthesia.CONCLUSION DAA is associated to good outcomes and lower incidence of dislocation.Complication rate can be reduced by mindful patient selection,thorough preoperative planning,sufficient learning curve and use of intraoperative imaging. | Fabrizio Rivera Luca C Comba Alessandro Bardelli | 2022 | World Journal of Orthopedics2022，13，4： | 2 |
| 5 | Damage detection in beam structures based on frequency measurements 显示文摘 | Fabrizio V Danilo C | 2000 | Journal of Engineering Mechanics2000，126，7： | 1 |
| 6 | The S100B protein in biological fluids:more than a lifelong biomarker of brain distress显示文摘 | Fabrizio M Valentina C | 2012 | Journal of Neurochemistry2012，120，6： | 1 |
| 7 | Diversity of mitochondrial DNA of the endangered white-clawed crayfish (Austropotamobius italicus ) in the Po River catchments 显示文摘 | Serena Z Fabrizio S Giuseppe C | 2005 | Freshwater Biol2005，50，7： | 1 |
| 8 | Arthroscopic treatment of cal- cifying tendonitis of the shoulder: clinical and uhrasonographic follow -up findings at two to five years 显示文摘 | Giuseppe P Paolo P Fabrizio C | 2004 | J Shoulder Elbow Surg2004，5，： | 1 |
| 9 | Long-term results of induction chemo therapy followed by concurrent chemotherapy and thoracic irradiation in limited small cell lung cancer显示文摘 | Ernesto M Lucio C Fabrizio P | 2002 | Lung Cancer2002，37，1： | 1 |
| 10 | Evidence for a biphasic apoptotic pathway induced by melatonin in MCF-7 breast cancer cells显示文摘 | Alessandra C Sara P Fabrizio D A | 2009 | J Pineal Res2009，46，3： | 1 |
| 11 | Effect of substrate grain size and surface treatments on the cutting properties of diamond coated co-cemented tungsten carbide tools显示文摘 | Riccardo P Fabio B Fabrizio C | 2002 | Diamond and Related Materials2002，11，： | 1 |
| 12 | Magnetite nanoparticles anchored to crystalline silicon surfaces显示文摘 | Fabrizio C Dino F Alberto F | 2005 | Chem Mater2005，17，12： | 1 |
| 13 | Spin density of ordered FeCo: a failure of the local-density approximation显示文摘 | Fabrizio E Di Mazzone G Petrillo C | 1989 | Phys Rev B1989，40，： | 1 |
| 14 | Comparison of electrolyzed oxidizing water with other antimicrobial interventions to reduce pathogens on fresh pork显示文摘 | FABRIZIO K A CUTTER C N | 2004 | Meat Science2004，68，3： | 1 |
| 15 | Sir2 blocks extreme life-span extension显示文摘 | Fabrizio P Gattazzo C Battistella L | 2005 | Cell2005，123，4： | 1 |
| 16 | Tight-binding potentials for transition metals and alloys显示文摘 | Fabrizio C Vittorio R | 1993 | Physical Review B1993，48，1： | 1 |
| 17 | Application of electrolyzed oxidizing water to reduce Listeria mon1ocytogenes on ready-to-eat meats显示文摘 | FABRIZIO K A CUTTER C N | | 0，，02： | 1 |
| 18 | Comparison of electrolyzed oxidizing water with other antimicrobial interventions to reduce pathogens on fresh pork显示文摘 | FABRIZIO K A CUTTER C N | | 0，，03： | 1 |
| 19 | Resistance to glycopeptide antibiotics in the teicoplanin producer is mediated by van gene homologue expression directing the synthesis of a modified cell wall peptidoglycan显示文摘 | Fabrizio B Arianna C | 2007 | Antimicrob Agent Chemother2007，51，4： | 1 |
| 20 | Stability of electrolyzed oxidizing water and its efficacy against cell suspensions of Salmonella TypHimurium and Listeria monocytogenes显示文摘 | Fabrizio K A Cutter C N | 2003 | Journal of Food Protection2003，66，8： | 1 |
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